Advances in Genetics
- 1st Edition, Volume 107 - February 25, 2021
- Editor: Dhavendra Kumar
- Language: English
- Hardback ISBN:9 7 8 - 0 - 1 2 - 8 2 4 1 2 3 - 3
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 2 4 1 2 4 - 0
Advances in Genetics, Volume 107, provides the latest information on the rapidly evolving field of genetics, presenting new medical breakthroughs that are occurring as a result… Read more
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Request a sales quote- Critically analyzes future directions for the study of clinical genetics
- Written and edited by recognized leaders in the field
- Presents new medical breakthroughs that are occurring as a result of advances in our knowledge of genetics
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Preface
- Chapter One: Advances in asthma genetics
- Abstract
- 1: Introduction
- 2: Asthma genetics
- 3: Epigenetics in asthma
- 4: Asthma and the microbiome
- 5: Pharmacogenomics of asthma
- 6: Precision medicine in asthma
- Chapter Two: Nutritional control of postembryonic development progression and arrest in Caenorhabditis elegans
- Abstract
- 1: Nutritional control of development in C. elegans—Why do we care?
- 2: C. elegans postembryonic development
- 3: Methods to measure developmental timing in C. elegans
- 4: Nutrient sensing pathways in C. elegans
- 5: Food deprivation provokes arrest at the L1 stage
- 6: Larval arrest at other stages
- 7: Diet-induced changes in developmental speed
- Acknowledgments
- Chapter Three: Diverse role of phytic acid in plants and approaches to develop low-phytate grains to enhance bioavailability of micronutrients
- Abstract
- 1: Introduction
- 2: Phytic acid structure, biosynthesis, and accumulation
- 3: Diverse roles of phytic acid
- 4: Antinutritional properties of phytic acid
- 5: Conventional and molecular breeding for low phytic acid lines
- 6: Transgene-based approaches to produce zero phytate grains
- 7: Conclusions
- Acknowledgments
- Chapter Four: Founder variants and population genomes—Toward precision medicine
- Abstract
- 1: Introduction
- 2: Resources cataloging founder variants
- 3: Population databases of human genetic variants
- 4: Approaches for detection of founder variants
- 5: Founder variations and genetic diseases across the world
- 6: Implications of founder mutations in public health
- 7: Challenges and future directions
- 8: Conclusions
- Chapter Five: Genomic perspectives on the circadian clock hypothesis of psychiatric disorders
- Abstract
- 1: Introduction: Circadian clocks and their role in mental health and psychiatric disorders
- 2: Phenotypic evidence for connections between circadian rhythms and psychiatric disorders
- 3: Predictions of circadian clock genes as candidate genes for psychiatric disorders
- 4: GWAS analysis of circadian phenotypes and psychiatric disorders, and the search for a connection
- 5: Conclusions
- Acknowledgments
- Chapter Six: Fungal natural products galaxy: Biochemistry and molecular genetics toward blockbuster drugs discovery
- Abstract
- 1: Introduction
- 2: Chemistry of fungal SMs
- 3: Drug discovery from fungi
- 4: Genomics of fungal secondary metabolic clusters
- No. of pages: 296
- Language: English
- Edition: 1
- Volume: 107
- Published: February 25, 2021
- Imprint: Academic Press
- Hardback ISBN: 9780128241233
- eBook ISBN: 9780128241240
DK
Dhavendra Kumar
Professor Dhavendra Kumar is a Visiting Professor, Genomic Policy Unit, Faculty of Life Sciences and Education, The University of South Wales and Consultant in Clinical Genetics at the University Hospital of Wales, Institute of Medical Genetics, Cardiff University, Cardiff, United Kingdom. He is one of the Consultants for the All Wales Medical Genetics Service and the lead Clinician for Clinical Cardiovascular Genetics. After qualifying in Medicine from the King George’s Medical College, University of Lucknow, India, he completed postgraduate training in Pediatrics with an MD. Since 1980 he has pursued a career in Medical Genetics in the UK. In 1990 he became a Diplomate of the American Board of Medical Genetics. He is a Fellow of the American College of Medical Genetics (FACMG) and as well as Royal Colleges of Physicians (FRCP-London and FRCP-Ireland) and Pediatrics and Child Health (FRCPCH-UK).
In 2015, he was conferred with the higher degree of DSc by his Alma Mater, King George’s Medical University, Lucknow (UP, India) based on his life-time contributions and achievements to genetic and genomic applications in medicine and health.