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Books in Life sciences

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    • Developmental Human Behavioral Epigenetics

      • 1st Edition
      • Volume 23
      • November 12, 2020
      • Livio Provenzi + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 9 2 6 2 7
      • eBook
        9 7 8 0 1 2 8 1 9 2 6 3 4
      Developmental Human Behavioral Epigenetics: Principles, Methods, Evidence, and Future Directions, Volume 23, a new volume in the Translational Epigenetics series, offers the first systematic account of theoretical G79 frameworks, methodological approaches, findings, and future directions in the field of human behavioral epigenetics. Featuring contributions from leading scientists and international researchers, this book provides a comprehensive overview of human behavioral epigenetics, with a close examination of evidence gathered to-date from animal models, challenges of human-based research and clinical translation, pathways towards drug discovery, and next steps in research. Areas of focus include prenatal stress exposures, preterm behavioral epigenetics, intergenerational exposures, trauma and neglect, socio-economic conditions, maternal caregiving and attachment, study design, and epigenetics and psychotherapy.

    • Tumor Immunology and Immunotherapy - Integrated Methods Part B

      • 1st Edition
      • Volume 636
      • March 15, 2020
      • English
      • Hardback
        9 7 8 0 1 2 8 2 0 6 6 7 6
      • eBook
        9 7 8 0 1 2 8 2 0 6 6 8 3
      Tumor Immunology and Immunotherapy - Integrated Methods Part B, Volume 636 in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Chapters in this update include Quantification methods of Transforming Growth Factor beta (TGF˗β) activity in the setting of cancer immunotherapy, Decoding cancer cell death-driven immune cell recruitment: An in vivo method for site-of-vaccination analyses, Tracking and interrogating tissue-resident and recruited microglia in brain tumors, Metabolomics and lipidomics of the tumor microenvironment, Monitoring abscopal responses to radiation in mice, and much more.

    • Medical Device Technologies

      • 2nd Edition
      • November 24, 2020
      • Gail Baura
      • English
      • Hardback
        9 7 8 0 1 2 8 1 1 9 8 4 6
      • eBook
        9 7 8 0 1 2 8 1 1 9 8 5 3
      Medical Device Technologies: A Systems Based Overview Using Engineering Standards, Second Edition, is a comprehensive overview of medical device technology, with a unified approach to each device area covering technical operation, clinical need, regulatory issues and standards and historical devices. It takes a systems-based view, balancing breadth with depth to give an accessible introduction to this field. Close ties are drawn between the design, the product and the patient. Exercises at the end of each chapter include traditional homework problems, analysis exercises and four questions from assigned primary literature. Eight laboratory experiments in both electrical and mechanical medical devices are explored. Each medical device chapter begins with an exposition of appropriate physiology, mathematical modeling or biocompatibility issues and clinical need. A device system description and system diagram provide details on technology function and administration of diagnosis and/or therapy. This systems approach enables the reader to quickly identify the relationships between devices.

    • Molecular Nutrition

      • 1st Edition
      • October 15, 2020
      • Manlio Vinciguerra + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 3 8 6 2 5
      • eBook
        9 7 8 0 1 2 8 1 3 8 6 3 2
      Molecular Nutrition: Mother and Infant presents the impact of diet in early life stages, from pre-conception, throughout pregnancy, and to the infant. The book covers the molecular biology of the cell, genetic machinery and its function, general coverage on diet and nutrition, pregnancy, placenta, weight gain, breast milk, feeding practices, gestational disease, glucose metabolism, immunity, vitamins and minerals. Other topics discusses include fetal programming, bioactive compounds, amino acids, intrauterine growth, one carbon metabolism, overnutrition, genetic risk factors, polymorphisms, folic acid genes, DNA methylation, genes involved in lipid metabolism, microRNAs, epigenetics, transcriptomics and micro RNA. This book will be a welcomed reference for research scientists and practitioners, including nutritionists and dieticians.

    • Gene Environment Interactions

      • 1st Edition
      • January 14, 2020
      • Moyra Smith
      • English
      • Paperback
        9 7 8 0 1 2 8 1 9 6 1 3 7
      • eBook
        9 7 8 0 1 2 8 1 9 7 9 7 4
      Gene Environment Interactions: Nature and Nurture in the Twenty-first Century offers a rare, synergistic view of ongoing revelations in gene environment interaction studies, drawing together key themes from epigenetics, microbiomics, disease etiology, and toxicology to illuminate pathways for clinical translation and the paradigm shift towards precision medicine. Across eleven chapters, Dr. Smith discusses interactions with the environment, human adaptations to environmental stimuli, pathogen encounters across the centuries, epigenetic modulation of gene expression, transgenerational inheritance, the microbiome’s intrinsic effects on human health, and the gene-environment etiology of cardiovascular, metabolic, psychiatric, behavioral and monogenic disorders. Later chapters illuminate how our new understanding of gene environment interactions are driving advances in precision medicine and novel treatments. In addition, the book's author shares strategies to support clinical translation of these scientific findings to improve heath literacy among the general population.

    • Strategies for Curative Fluorescence-Guided Surgery of Cancer

      • 1st Edition
      • May 27, 2020
      • Robert Hoffman + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 2 5 7 6 2
      • eBook
        9 7 8 0 1 2 8 1 2 6 7 7 6
      Strategies for Curative Fluorescence-Guided Surgery of Cancer is the first book to discuss how fluorescence-guided surgery can be successfully used during surgeries with several tumor types. FGS is one of the most exciting emerging modalities of surgery, especially cancer surgery, as it potentially allows the surgeon to visualize the actual margin of the tumor, thus greatly increasing the possibility of curative resection. The book discusses the applicability of FGS for several types of cancer, such as pancreatic cancer, liver metastasis, soft-tissue sarcoma, glioma, melanoma, and breast and lung cancer. This book is a valuable resource for cancer surgeons, cancer researchers and members of several other areas in the biomedical field who are interested in understanding this powerful technique.

    • Peyronie's Disease: Pathophysiology and Treatment

      • 1st Edition
      • May 13, 2020
      • Giorgio Ivan Russo + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 9 4 6 8 3
      • eBook
        9 7 8 0 1 2 8 2 0 5 7 5 4
      Peyronie's Disease: Pathophysiology and Treatment combines the basic research of Peyronie’s Disease with an overview of the clinical and practical management of the disease, providing the most comprehensive approach. Coverage includes etiology and psychological aspects of the disease, management according to European and US guidelines for both surgical and non-surgical treatments, and oral therapies and on-going research including stem cells. This book is perfect for urologists—particula... those who specialize in sexual medicine and/or infertility—and for Andrologists and Endocrinologists.

    • Storing Digital Binary Data in Cellular DNA

      • 1st Edition
      • August 18, 2020
      • Rocky Termanini
      • English
      • Hardback
        9 7 8 0 3 2 3 8 5 2 2 2 7
      • eBook
        9 7 8 0 1 2 8 2 3 4 5 8 7
      Storing Digital Binary Data into Cellular DNA demonstrates how current digital information storage systems have short longevity and limited capacity, also pointing out that their production and consumption of data exceeds supply. Author Rocky Termanini explains the DNA system and how it encodes vast amounts of data, then presents information on the emergence of DNA as a storage technology for the ever-growing stream of data being produced and consumed. The book will be of interest to a range of readers looking to understand this game-changing technology, including researchers in computer science, biomedical engineers, geneticists, physicians, clinicians, law enforcement and cybersecurity experts.

    • Treatment of Movement Disorders, An Issue of Neurologic Clinics

      • 1st Edition
      • Volume 38-2
      • April 27, 2020
      • Joseph Jankovic
      • English
      • Hardback
        9 7 8 0 3 2 3 7 0 9 9 1 0
      • eBook
        9 7 8 0 3 2 3 7 0 9 9 2 7
      In collaboration with Consulting Editor, Randolph W. Evans, Dr. Joseph Jankovic has put together an issue of Neurologic Clinics devoted to Treatment of Movement Disorders. Topics include, but are not limited to, Clinical Rating Scales and Quantitative Assessments of Movement Disorders, Pharmacologic Treatment of Motor Symptoms Associated with Parkinson’s Disease, Treatment of Non-Motor Symptoms Associated with Parkinson’s Disease, Surgical Treatment of Parkinson’s Disease, Emerging Medical and Surgical Treatments of Essential Tremor, Medical and Surgical Treatments of Dystonia, Medical and Surgical Treatments of Tourette Syndrome, Medical, Genetic and Surgical Treatments of Huntington Disease, Treatment of Tardive Dyskinesia, Medical and Surgical Treatments of Cerebral Palsy, Treatment of Wilson Disease, Treatment of Paroxysmal Dyskinesias, Treatment of Ataxia, and Treatment of Functional (Psychogenic) Movement Disorders.

    • Practical Paediatric Prescribing

      • 1st Edition
      • April 24, 2020
      • Will Carroll + 4 more
      • English
      • Paperback
        9 7 8 0 7 0 2 0 7 6 1 2 1
      Prescribing for children is problematic. Children are not small adults in terms of their physiology, and they cannot be subjects in clinical trials. This makes prescribing for them something of an art and a daunting one at that for trainees. Will Carroll (co-editor of the Illustrated Textbook of Paediatrics amongst other titles for paediatrics trainees) with a team of fellow paediatricians and a hospital pharmacist have sought to demystify prescribing for children. The team has identified what from their experience are the most common drugs prescribed to children and have addressed each one, adding detail about how each medicine works. Each chapter follows the ABCDE structure covering Absorption, Biological effects, Clearance, Dosing and side Effects in children. This book is a succinct, portable reference, modelled closely on Hitchings et al.: The Top 100 Drugs.

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