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    • Epigenetics of Exercise and Sports

      • 1st Edition
      • Volume 25
      • July 13, 2021
      • Stuart M Raleigh
      • English
      • Paperback
        9 7 8 0 1 2 8 2 0 6 8 2 9
      • eBook
        9 7 8 0 1 2 8 2 0 9 3 7 0
      Epigenetics of Exercise and Sports: Concepts, Methods, and Current Research explains fundamental epigenetic processes and how these are altered by exercise and sports. After a brief review of fundamental epigenetic biology, this all-new volume in the Translational Epigenetics series offers step-by-step instruction in how epigenetic factors are investigated for their influence over exercise related traits of human physiology, disease, and injury. The current state of knowledge in the field and recent findings are discussed in-depth, illuminating how exercise and sports performance may epigenetically modify our physiology, disease and injury risks, and how this knowledge can be applied in personalized exercise approaches, diagnostics, and treatment. This book also explores the shortcomings of explaining exercise related phenomena using only genomics and traditional biochemical techniques, setting the scene for a paradigm shift in exercise biology. In addition, over a dozen international specialists contribute chapters on exercise and sports epigenetics, and their influence over metabolism, obesity, aging, immunity, and neurological disease, as well as the epigenetic impacts of concussions and sports doping. A concluding chapter discusses ongoing themes in the field and outlooks for future research.

    • iPSCs for Studying Infectious Diseases

      • 1st Edition
      • May 29, 2021
      • Alexander Birbrair
      • English
      • Paperback
        9 7 8 0 1 2 8 2 3 8 0 8 0
      • eBook
        9 7 8 0 1 2 8 2 4 1 8 9 9
      The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. iPSCs for Studying Infectious Diseases, Volume 8 addresses how important induced pluripotent stems cells are and how can they can help treat certain infectious diseases. Somatic cells can be reprogrammed into induced pluripotent stem cells by the expression of specific transcription factors. These cells have been transforming biomedical research over the last 15 years. This volume will address the advances in research of how induced pluripotent stem cells are being used for treatment of different infectious diseases, such as corona virus, coxsackievirus, salmonella infection, influenza virus and much more. The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation; and is contributed by world-renowned authors in the field.

    • Brain Tumor MRI Image Segmentation Using Deep Learning Techniques

      • 1st Edition
      • November 27, 2021
      • Jyotismita Chaki
      • English
      • Paperback
        9 7 8 0 3 2 3 9 1 1 7 1 9
      • eBook
        9 7 8 0 3 2 3 9 8 3 9 5 2
      Brain Tumor MRI Image Segmentation Using Deep Learning Techniques offers a description of deep learning approaches used for the segmentation of brain tumors. The book demonstrates core concepts of deep learning algorithms by using diagrams, data tables and examples to illustrate brain tumor segmentation. After introducing basic concepts of deep learning-based brain tumor segmentation, sections cover techniques for modeling, segmentation and properties. A focus is placed on the application of different types of convolutional neural networks, like single path, multi path, fully convolutional network, cascade convolutional neural networks, Long Short-Term Memory - Recurrent Neural Network and Gated Recurrent Units, and more. The book also highlights how the use of deep neural networks can address new questions and protocols, as well as improve upon existing challenges in brain tumor segmentation.

    • Introductory Microbiology Lab Skills and Techniques in Food Science

      • 1st Edition
      • November 2, 2021
      • Cangliang Shen + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 2 1 6 7 8 1
      • eBook
        9 7 8 0 1 2 8 2 3 2 4 3 9
      Introductory Microbiology Lab Skills and Techniques in Food Science covers topics on isolation, identification, numeration and observation of microorganisms, biochemistry tests, case studies, clinical lab tasks, and basic applied microbiology. The book is written technically with figures and photos showing details of every lab procedure. This is a resource that is skills-based focusing on lab technique training. It is introductory in nature, but encourages critical thinking based on real case studies of what happens in labs every day and includes self-evaluation learning questions after each lab section. This is an excellent guide for anyone who needs to understand how to apply microbiology to the lab in a practical setting.

    • Bioinspired and Biomimetic Materials for Drug Delivery

      • 1st Edition
      • July 15, 2021
      • Md Nurunnabi
      • English
      • Paperback
        9 7 8 0 1 2 8 2 1 3 5 2 0
      • eBook
        9 7 8 0 1 2 8 2 1 9 4 9 2
      Bioinspired and Biomimetic Materials for Drug Delivery delves into the potential of bioinspired materials in drug delivery, detailing each material type and its latest developments. In the last decade, biomimetic and bioinspired materials and technology has garnered increased attention in drug delivery research. Various material types including polymer, small molecular, protein, peptide, cholesterol, polysaccharide, nano-crystal and hybrid materials are widely considered in drug delivery research. However, biomimetic and bioinspired materials and technology have shown promising results for use in therapeutics, due to their high biocompatibility and reduced immunogenicity. Such materials include dopamine, extracellular exosome, bile acids, ionic liquids, and red blood cell. This book covers each of these materials in detail, reviewing their potential and usage in drug delivery. As such, this book will be a great source of information for biomaterials scientists, biomedical engineers and those working in pharmaceutical research.

    • Monoclonal Antibodies

      • 1st Edition
      • August 3, 2021
      • Harleen Kaur + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 2 2 3 1 8 5
      • eBook
        9 7 8 0 1 2 8 2 2 3 1 9 2
      Monoclonal antibodies (mAbs) are naturally occurring complex biomolecules. New engineering methods have turned mAbs into a leading therapeutic modality for addressing immunotherapeutic challenges and led to the rise of mAbs as the dominant class of protein therapeutics. mAbs have already demonstrated a great potential in developing safe and reliable treatments for complex diseases and creating more affordable healthcare alternatives. Developing mAbs into well-characterized antibody therapeutics that meet regulatory expectations, however, is extremely challenging. Obstacles to overcome include the determination and development of physiochemical characteristics such as aggregation, fragmentation, charge variants, identity, carbohydrate structure, and higher-order structure (HOS). This book dives deep into mAbs structure and the array of physiochemical testing and characterization methods that need to be developed and validated to establish a mAb as a therapeutic molecule. The main focus of this book is on physiochemical aspects, including the importance of establishing quality attributes such as glycosylation, primary sequence, purity, and HOS and elucidating the structure of new antibody formats by mass spectrometry. Each of the aforementioned quality attributes has been discussed in detail; this will help scientists in researching and developing biopharmaceuticals and biosimilars to find practical solutions to physicochemical testing and characterization.

    • Polycystic Ovary Syndrome

      • 1st Edition
      • November 25, 2021
      • Evanthia Diamanti-Kandarakis
      • English
      • Paperback
        9 7 8 0 1 2 8 2 3 0 4 5 9
      • eBook
        9 7 8 0 1 2 8 2 3 0 4 6 6
      Women’s healthcare regarding polycystic ovarian syndrome remains challenging. Patients often go from one specialist to another trying to fully understand and management the disorder. Women often go years before a diagnosis, seeing three or more doctors before a confirmed diagnosis. Polycystic Ovarian Syndrome: Challenging Issues in the Modern Era of Individualized Medicine brings together multiple medical disciplines to improve the care of women with PCOS. Such a multidisciplinary clinical and scientific approach integrates obstetrics and gynecology, pediatric and medical endocrinology, internal medicine, genetics, psychology and laboratory medicine into relevant translational clinical and scientific discussions that update both the scientific understanding of PCOS and the diagnosis and management of all aspects of the syndrome. The impact of PCO on the onset of puberty is subdivided in sub sections to get a better understanding of this condition and the management at different stages in a woman’s life.

    • Environmental and Health Management of Novel Coronavirus Disease (COVID-19)

      • 1st Edition
      • June 25, 2021
      • Mohammad Hadi Dehghani + 2 more
      • English
      • Paperback
        9 7 8 0 3 2 3 8 5 7 8 0 2
      • eBook
        9 7 8 0 3 2 3 9 0 9 2 4 2
      Environmental and Health Management of Novel Coronavirus Disease (COVID-19) examines mitigation measures that can be adopted at the time of a novel coronavirus outbreak to lessen environmental contamination and impacts on human health. The book discusses origin, structure and pathogenesis, epidemiology, environmental transmission and the potential spread routes of COVID-19 via surfaces, air, water, wastewater, medical waste and food products. It also covers guidelines and protocols for setting safety conditions to provide adequate health care and reduce the risk of infection in health and non-healthcare settings, along with preventative measures and disinfection technologies. In addition, the book discusses challenges, opportunities and future perspectives, the global crisis, and global consequences on the environment and health. With contributions from experts, this book presents a multidisciplinary reference resource for virologists, microbiologists, public health professionals, environmental health managers and others engaged in the study and mitigation of the environmental and health impacts of the virus.

    • Peacock Bass

      • 1st Edition
      • March 15, 2021
      • Kirk O. Winemiller + 2 more
      • English
      • Hardback
        9 7 8 0 3 2 3 8 5 1 5 7 2
      • eBook
        9 7 8 0 3 2 3 8 5 9 6 9 1
      Peacock Bass: Diversity, Ecology, and Conservation is a unique scientific reference that describes not only the diversity and natural history of the various peacock bass species (fish in the genus Cichla) but also their geographic distributions, evolutionary relationships, ecology, and economic importance. Peacock bass are the most popular sport fish pursued by recreational anglers in tropical freshwaters, and they support important fisheries in rivers and lakes in their native South America as well as other regions of the world where they have been introduced. The book is written in clear prose that allows any reader to appreciate key features of the morphology, population genetics, and reproductive biology of these colorful tropical freshwater fish. Each chapter begins with a vignette introducing an aspect of peacock bass taxonomy, ecology, or conservation based on a personal account from one of the authors. Also included are color photographs of peacock bass, their habitats, other tropical fishes, and the diverse wildlife encountered in rivers and forests of the Neotropics. Photographic guides and detailed descriptions of coloration patterns are provided for species identification, along with distribution maps and essential information related to fisheries management and the economic importance of peacock bass. Biologists interested in zoogeography and the ecological role peacock bass play as major predators in biodiverse rivers and lakes will find summaries of the latest information. Peacock bass have grown in popularity among aquarists, and the book provides basic information about captive care and environmental conditions in their natural habitats. This book is essential reading for biologists, fisheries managers, anglers, naturalists, and aquarists interested in these remarkable fish and the diverse tropical rivers they inhabit.

    • Medical Epigenetics

      • 2nd Edition
      • Volume 29
      • August 26, 2021
      • English
      • Paperback
        9 7 8 0 1 2 8 2 3 9 2 8 5
      • eBook
        9 7 8 0 1 2 8 2 4 3 2 6 8
      **Selected for Doody’s Core Titles® 2024 in Clinical Genetics**Medical Epigenetics, Second Edition provides a comprehensive analysis of epigenetics in health management, across a broad spectrum of disease categories and specialties, and with a focus on human systems, epigenetic diseases that affect these systems, and evolving modes of epigenetic-based treatment. Here, more than 40 leading researchers examine how each human system is affected by epigenetic maladies, offering an all-in-one resource on medical epigenetics not only for those directly involved with health care, but investigators in life sciences, biotech companies, graduate students, and others who are interested in applied aspects of epigenetics. Incorporating both diagnostic and prognostic epigenetic approaches, this volume also fully supports the application of epigenetics in precision medicine.This second edition of Medical Epigenetics, a volume in the Translational Epigenetics series, has been fully revised to address recent advances in disease epigenetics and role of epigenetics in precision medicine, with all-new chapters on skin cancer epigenetics, network analysis in medical epigenetics, machine learning in epigenetic diseases, and clinical trials of epigenetics drugs.

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