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Elsevier

Books in Life sciences

  • Movement Disorders in Childhood

    • 3rd Edition
    • Harvey S. Singer + 3 more
    • English
    Movement Disorders in Childhood, Third Edition provides the most up-to-date information on the diseases and disorders that affect motor control, an important area of specialization within child neurology. In this new edition, each chapter has been fully revised to include all of the latest scientific and therapeutic advances. Updates include new insights in motor development, control, goal-directed and habitual behaviors, classifications of movements and their complex and integrated circuitry. The authors also discuss developments in pathophysiologic mechanisms, immunology and metabolic disorders. New chapters include coverage of genetics of movement disorders and movement disorders in psychiatric conditions.Appendice... include an updated and revised drug index and genetic search strategy. An updated Companion website hosts selected educational videos to help diagnose movement disorders.

  • Nuclear Medicine and Molecular Imaging

    • 1st Edition
    • Alberto Signore
    • English
    Nuclear Medicine and Molecular Imaging offers complete coverage of this exciting and key area of biomedicine, seamlessly fusing the science behind nuclear medicine with the clinical aspects of diagnostic imaging. Beginning with sections on the physics related to nuclear medicine, radiation biology/safety, and instrumentation/qual... control, it then covers radiochemistry and the development of new radionuclide therapy/tracers, and basic techniques such as positron emission tomography (PET) and single photon emission computed tomography (SPECT). The focus then shifts to the clinical aspects, with sections on clinical/preclinical nuclear imaging (structured via organ system such as gastrointestinal, cardiovascular, pulmonary, etc.), as well as other in vivo molecular imaging techniques such as optical imaging, digital image analysis (radiomics), as well as the increasing use of artificial intelligence (AI) in diagnostics. No other publication provides such a complete overview of the field, with most choosing to focus either on physics or imaging. In most cases, preclinical/experime... imaging is treated separately from clinical imaging. Nuclear Medicine and Molecular Imaging brings it all together into a complete, 4-volume, foundational resource for researchers and medical professionals specializing in this exciting area.

  • Human-Gut Microbiome

    Establishment and Interactions
    • 1st Edition
    • Gunjan Goel + 2 more
    • English
    Human-Gut Microbiome: Establishment and Interactions gives an overview of microbiome establishments in humans and basic technologies used to decipher the structure and function of gut microbiome. Other sections focus on the application of microbiomics in different disease manifestations, such as obesity, diabetes, and more. The book provides the basics, as well as mechanistic knowledge underpinning the structural and functional understanding of the microbiome. With the advancement in omics technologies, as well as the development of bioinformatic tools, much research has been undertaken to decipher the microbiomes of different hosts. This research is generating valuable insights into micro-ecological niches and their impact on humans, hence this new release covers these new insights. The book will be a valuable resource for scientists, researchers, postgraduate and graduate students who are interested in understanding the impact and importance of the omics approach to humans and their microbiomes.

  • Spine Phenotypes

    • 1st Edition
    • Dino Samartzis + 2 more
    • English
    The era of big data and personalized spine care has arrived. Within that, imaging and clinical phenotypes are key in establishing personalized algorithms for patient care. This is particularly important in developing novel diagnostics and therapeutics as well as predicting outcomes and establishing preventative measures for various spinal disorders. Spine Phenotypes is a comprehensive resource that outlines phenotype descriptions, their imaging measurements and classifications, and provides an in-depth discussion regarding spine pathology and its clinical relevance. Multiauthored, with multidisciplinary contributions from world leaders in the field of imaging, spine research, and clinical practice, each chapter is rich in visual depiction of imaging phenotypes, providing examples of some established phenotypic measurements with a range of normal and pathologic images and their clinical implications. Spine Phenotypes will be a first of its kind reference for spine researchers, clinicians, and industry.

  • Methods in Stem Cell Biology - Part A

    • 1st Edition
    • Volume 170
    • English
    Methods in Cancer Stem Cell Biology: Part A, Volume 170 in the Methods in Cell Biology series highlights advances in the field, with this new volume presenting interesting chapters on timely topics, including Orthotopic brain tumor models derived from glioblastoma stem-like cells, RNA sequencing in hematopoietic stem cells, Generation of inducible pluripotent stem cells from human dermal fibroblasts, In vitro preparation of dental pulp stem cell grafts combined with biocompatible scaffolds for tissue engineering, Gene expression knockdown in chronic myeloid leukemia stem cells, Identification and isolation of slow-cycling GSCs, Assessment of CD133, EpCAM, and much more.

  • Coronavirus Drug Discovery

    Volume 2: Antiviral Agents from Natural Products and Nanotechnological Applications
    • 1st Edition
    • Chukwuebuka Egbuna
    • English
    Coronavirus Drug Discovery, Volume Two: Antiviral Agents from Natural Products and Nanotechnological Applications presents detailed information on drug discovery against COVID-19. Sections in this volume present chapters that focus on the various antiviral agents from natural products that have the propensity to be used as chemical scaffolds for the development of drugs against COVID-19. Also captured are the dietary sources of antioxidant bioactives that may help boost the immune system for the management of COVID-19. Other chapters describe the application of nanotechnology for efficient and effective delivery of drugs against COVID-19. Written by global team of experts, this book is an excellent resource for drug developers, medicinal chemists, pharmaceutical companies in R&D and research institutes in both academia and industry.

  • Allgemeine und spezielle Pharmakologie und Toxikologie

    • 13th Edition
    • Klaus Aktories + 3 more
    • German
    Wer mit „Aktories" lernt, versteht Das Standardwerk der Pharmakologie und Toxikologie in überarbeiteter 13. Auflage: das gesamte Wissen auf über 1.000 Seiten. Bewährt als erstklassiges Lehrbuch für Medizin- und Pharmaziestudierende... begehrt als Nachschlagewerk für Medizinier*innen und Pharmakolog*innen. Das gesamte Wissen der Pharmakologie und Toxikologie wird Ihnen hier verständlich und anschaulich erklärt und bringt Ihnen Sichherheit beim Lernen: Arzneimittelwirkunge... im Gesamtzusammenhang begreifen: Wirkmechanismen und pathophysiologische Bezüge in jedem Kapitel Zusammenhänge verstehen: Ausführliches Kapitel zur allgemeinen Pharmakologie und Toxikologie erleichtert Ihnen das Verständnis der speziellen pharmakologischen Zusammenhänge Praktische Relevanz: Empfehlungen zu Therapie und Dosierungen finden Sie in farbig hervorgehobenen Kästen Neu in der 13. Auflage: Hoch aktuelle Darstellung der Biologika (= das Gebiet der Pharmakologie, das am schnellsten wächst): signifikante Neuentwicklungen für die Tumortherapie, der Therapie rheumatischer Erkrankungen und anderer Autoimmunerkrankunge... der Therapie allergischer Erkrankungen und der Therapie der Psoriasis (Schuppenflechte) Bemerkenswerte Erkenntnisse bei der Einführung der SGLT-2-Inhibitoren (Sodium-Glucose-Like... 2) in der Diabetes-Typ2-Therap... Darstellung der vielfältigen Zusammenhänge von molekular-pharmakolo... Wirkungen der Arzneimittel und ihrer therapeutischen Anwendung (inklusive der mRNA-Technologie) Neue Arzneimittelentwickl... Ergänzung der IMPP-Arzneistofflist... (Markierung im Fließtext + eigenes Register)

  • Essential Neuromodulation

    • 2nd Edition
    • Jeffrey Arle + 1 more
    • English
    Essential Neuromodulation, Second Edition is a concise reference covering all of the basic principles of neuromodulation in a single affordable volume for neuroscientists, residents, fellows, bioengineers and basic clinical practitioners. This second edition expands on developments in the field since 2011, emphasizing essential observations from all of the important clinical phases involved in any neuromodulation: targeting, intraoperative assessment, programming, complications and complication avoidance. As neuromodulation remains an exciting and rapidly advancing field, this information is critical for neurosurgeons, neurophysiologists, bioengineers and other proceduralists.

  • Protein Interaction Networks

    • 1st Edition
    • Volume 131
    • Rossen Donev
    • English
    Protein Interaction Networks, Volume 131 in the Advances in Protein Chemistry and Structural Biology series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

  • Coronavirus Drug Discovery

    Volume 3: Druggable Targets and In Silico Update
    • 1st Edition
    • Chukwuebuka Egbuna
    • English
    Coronavirus Drug Discovery, Volume Three: Druggable Targets and In Silico Update presents comprehensive information on drug discovery against COVID-19. Chapters in Part One of this volume describe the various druggable targets and associated signaling pathways for effective targeting of SARS-CoV-2. In Part Two, chapters discuss the various computational approaches and in silico studies against SARS-CoV-2. Written by global team of experts, this book is an excellent resource that will be extremely useful to drug developers, medicinal chemists, pharmaceutical companies in R&D, research institutes in both academia and industry, and the National Library of Medicines and Health. In addition, agencies such as the National Institutes of Health, Centers for Disease Control and Prevention, World Health Organization, European Medicines Agency, the US Food and Drug Administration, and all others involved in drug discovery against COVID-19 will find this book useful.

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