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Books in Life sciences

    • Handbook of Basic and Clinical Ocular Pharmacology and Therapeutics

      • 1st Edition
      • July 25, 2022
      • Sunny Ohia + 1 more
      • English
      • Paperback
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      • eBook
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      Handbook of Basic and Clinical Ocular Pharmacology and Therapeutics provides a review of the basic anatomy, physiology, biochemistry and pathology of the eye with a focus drug therapy, drug delivery and use of therapeutic medical miniature devices. An understanding of the pharmacological actions of drugs acting on the eye requires the student and health care practitioner to learn additional principles in basic and clinical sciences that are unique to this organ. As a sensory organ, the eye is relatively inaccessible to the systemic circulation due to the blood-vitreous, blood-aqueous and blood-retinal barriers. Consequently, the administration of drugs for therapeutic effects in the eye necessitates an understanding of physico-chemical properties of the molecules and pharmacokinetic principles involved in the access to its site of action via topical, intracameral and intravitreal administration. This book includes information on the general principles of pharmacokinetics and pharmacodynamics of drugs as it pertains to the eye and in combating ocular disorders and diseases. Using a disease-themed approach, the book discusses basic and clinical pharmacological principles involved in the therapy of these diseases including the ocular side effect of systemically-adminis... drugs, drugs used in ophthalmic surgery and miscellaneous agents, the therapeutic utility of biologics, drug conjugates, combination products, gene and cellular therapy are also covered. Handbook of Basic and Clinical Ocular Pharmacology and Therapeutics is useful as a primary and secondary source of reference for up-to-date information about the pharmacological mechanisms of action, pharmacokinetics, side effects, drug-drug interactions and therapeutic indications of drugs for pharmacologists, pharmaceutical scientists, students in the health care disciplines (nursing, pharmacy, optometry, medical), and practitioners in optometry and ophthalmology.
    • Perinatal and Developmental Epigenetics

      • 1st Edition
      • Volume 35
      • December 2, 2022
      • Garima Singh
      • English
      • Paperback
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      • eBook
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      Perinatal and Developmental Epigenetics, Volume 32, a new volume in the Translational Epigenetics series, provides a thorough overview of epigenetics in the early developmental and perinatal stages, illuminating pathways for drug discovery and clinical advances. Here, over 25 international researchers examine recent steps forward in our understanding of epigenetic programming during perinatal and early development. The book opens with an in-depth introduction to known and newly discovered epigenetic marks and how they regulate various cellular processes. Later sections examine various prenatal and perinatal environmental experiences and their ability to derail the normal developmental trajectory via epigenetic reprogramming. Insights and suggestions for future research illuminate approaches for identifying individual disease susceptibility. Concluding chapters highlight preventative and targeted therapeutic pathways to improve quality of life into adulthood.
    • Mass Production of Beneficial Organisms

      • 2nd Edition
      • September 20, 2022
      • Juan A. Morales-Ramos + 2 more
      • English
      • Hardback
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      • eBook
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      Mass Production of Beneficial Organisms: Invertebrates and Entomopathogens, Second Edition explores the latest advancements and technologies for large-scale rearing and manipulation of natural enemies while presenting ways of improving success rate, predictability of biological control procedures, and demonstrating their safe and effective use. Organized into three sections, Parasitoids and Predators, Pathogens, and Invertebrates for Other Applications, this second edition contains important new information on production technology of predatory mites and hymenopteran parasitoids for biological control, application of insects in the food industry and production methods of insects for feed and food, and production of bumble bees for pollination.Benefici... organisms include not only insect predators and parasitoids, but also mite predators, nematodes, fungi, bacteria and viruses. In the past two decades, tremendous advances have been achieved in developing technology for producing these organisms. Despite that and the globally growing research and interest in biological control and biotechnology applications, commercialization of these technologies is still in progress. This is an essential reference and teaching tool for researchers in developed and developing countries working to produce “natural enemies” in biological control and integrated pest management programs.
    • Physicochemical Interactions of Engineered Nanoparticles and Plants

      • 1st Edition
      • October 12, 2022
      • Guadalupe De La Rosa + 1 more
      • English
      • Paperback
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      • eBook
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      Physicochemical Interactions of Engineered Nanoparticles and Plants: A Systemic Approach, Volume Four in the Nanomaterial-Plant Interactions series, presents foundational information on how ENMs interact with the surrounding environment. Key themes include source, fate and transport of ENMs in the environment, biophysicochemical transformations of ENMs, and chemical reactions and mechanisms of ENMs transport in plants. This book is an essential read for any scientist or researcher looking to understand the molecular interactions between ENMs and Plants. Engineered nanomaterials (ENMs) reach plant ecosystems through intentional or unintentional pathways. In any case, after release, these materials may be transformed in the environment by physical, chemical and biochemical processes. Once in contact with plant systems, biotransformation may still occur, affecting or stimulating plant metabolism. Since plants are the producers to the food chain, it is of paramount importance to understand these mechanisms at the molecular level.
    • Obesity and Esophageal Disorders

      • 1st Edition
      • June 25, 2022
      • Dhyanesh Patel + 3 more
      • English
      • Paperback
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      • eBook
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      Obesity and Esophageal Disorders is a comprehensive review on the impact of obesity on esophageal disorders and how to approach, recognize and treat those disorders. Covering the critical gap in awareness on the impact of obesity on esophageal disorders, this reference presents the newest diagnostic technologies, including high resolution manometry, EndoFLIP, wireless pH monitoring, and mucosal integrity devices. The book shows treatment options like bariatric surgery and endo-bariatrics that decrease the latency period for diagnosis and management of patients. Finally, the understanding of the potential effects of different bariatric surgeries on esophageal motility is explored. This importance reference serves researchers looking to determine future projects by providing novel pathophysiologic mechanisms about how obesity affects GERD and esophageal motility. It serves clinicians, surgeons and trainees with guidance on diagnostic approaches, management options, and how to recognize/treat post-surgical esophageal complications of patients with obesity.
    • Biotechnology in Healthcare, Volume 1

      • 1st Edition
      • March 30, 2022
      • Debmalya Barh
      • English
      • Paperback
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      • eBook
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      Biotechnology in Healthcare, Technologies and Innovations, Volume One presents up-to-date knowledge on the emerging field of biotechnology as applied to the healthcare industry. Sections cover 3D printing, tissue engineering, synthetic biology, nano-biotechnology, omics, precision medicine, gene therapy, vaccine development, predictive healthcare, entrepreneurship, financing, business models, product development and marketing in the sector. This is a valuable source for biotechnologists, bioinformaticians, clinicians and members of biomedical and healthcare fields who need to understand more about the promising developments of the emerging field of biotechnology in healthcare.
    • Digital Agritechnology

      • 1st Edition
      • August 24, 2022
      • Toby Mottram
      • English
      • Paperback
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      • eBook
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      Digital Agritechnology: Robotics and Systems for Agriculture and Livestock Production describes how systems acquire and use data in livestock production and agricultural systems, and how researchers can extract and aggregate efficiencies. The origins of digital agritechnology are decades old, with robotic milkers available for over 20 years and GPS-based tractor controls existing for nearly 30. However, only a few capabilities of these sensing and control systems are used. This book addresses the need to educate agriculturists on the full usage scale of these arable and livestock systems.
    • Recent Advances and Future Perspectives of Microbial Metabolites

      • 1st Edition
      • October 23, 2022
      • Surajit de Mandal + 4 more
      • English
      • Paperback
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      • eBook
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      Recent Advances and Future Perspectives of Microbial Metabolites: Applications in Biomedicine sheds new light on various applications of microbial metabolites in the biomedical sector. The purpose of this book is to integrate the latest research advancements on the application of microbial metabolites in the medical industry into a single platform. In 10 chapters, the significance of biomedical applications and future therapeutic applications of microbial metabolites in human health are highlighted. Several chapters are dedicated to the role of microbial metabolites in precision medicine like the impact of the activities of microbial metabolites in antitumor and antidiabetic agents and immunosuppressive activities. It also provides a roadmap for drugs discovery based on antimicrobial products and the effect of microbial metabolites on humans’ health and the immune system. The book finalizes with a chapter on the use of microbial metabolites in OMICS technology. Recent Advances and Future Perspectives of Microbial Metabolites: Applications in Biomedicine targets researchers from both academia and industry, professors, and graduate students from microbiology, molecular biology, biotechnology, and immunology.
    • Genomic and Precision Medicine

      • 3rd Edition
      • April 9, 2022
      • Geoffrey S. Ginsburg + 3 more
      • English
      • Hardback
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      • eBook
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      Genomic and Precision Medicine: Oncology, Third Edition focuses on the applications of genome discovery as research points to personalized cancer therapies. Each chapter is organized to cover the application of genomics and personalized medicine tools and technologies to a) Risk Assessment and Susceptibility, b) Diagnosis and Prognosis, c) Pharmacogenomics and Precision Therapeutics, and d) Emerging and Future Opportunities in the field.
    • Computational Models in Biomedical Engineering

      • 1st Edition
      • September 11, 2022
      • Milos Kojic + 2 more
      • English
      • Paperback
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      • eBook
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      Computational Models in Biomedical Engineering: Finite Element Models Based on Smeared Physical Fields: Theory, Solutions, and Software discusses novel computational methodologies developed by the authors that address a variety of topics in biomedicine, with concepts that rely on the so-called smeared physical field built into the finite element method. A new and straightforward methodology is represented by their Kojic Transport Model (KTM), where a composite smeared finite element (CSFE) as a FE formulation contains different fields (e.g., drug concentration, electrical potential) in a composite medium, such as tissue, which includes the capillary and lymphatic system, different cell groups and organelles. The continuum domains participate in the overall model according to their volumetric fractions. The governing laws and material parameters are assigned to each of the domains. Furthermore, the continuum fields are coupled at each FE node by connectivity elements which take into account biological barriers such as vessel walls and cells.