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Elsevier

Books in Life sciences

  • Circadian Rhythms, Sleep, and Sleep Disorders

    • 1st Edition
    • Volume 206
    • English
    Circadian rhythms, sleep, and sleep disorders covers the topic in two sections focusing on basic science and clinical application. In the basic section, new developments and research findings focusing on basic circadian rhythm and sleep physiology in animals and humans is highlighted. The chapters are written in short mini-review formats in order to concisely describe the fundamentals, and current hot topics.The basic part starts with a chapter on the fundamentals and new discoveries on oscillating circuitries in the sleeping rodent and human brain. This sets the stage for chap 2, focusing on circadian and homeostatic aspects of human sleep regulation. Chap 3 extends these aspects to human cognition. The next chapter reports on visual and non-visual effects of light on human behavior, particularly endocrine and electrophysiological correlates. Chap 5 covers chronic sleep restriction effects on functional connectivity states. The last two chapters (6 and 7) give a broad overview on sleep modeling across physiological levels, with a focus on a quantitative model of sleep-wake dynamics based on the physiology of the brainstem ascending arousal system.The clinical section of the book describes the circadian rhythm sleep-wake disorders, from epidemiology to clinical picture and treatment. Disorders covered include delayed and advanced sleep phase syndrome, Irregular sleep-wake rhythm disorder, shift work disorder, restless legs syndrome, nocturnal eating syndrome, narcolepsy, and sleep apnea. Pharmacological and non-pharmacological treatments of insomnia are explored, as well as the role of sleep-wake modulation in the pathogenesis and clinical profile of neurodegenerative disorders, such as Parkinson’s disease and Alzheimer’s disease.

  • Nuclear Proteins

    • 1st Edition
    • Volume 143
    • English
    Advances in Protein Chemistry and Structural Biology, Volume 143 in the series, covers reviews of methodology and research in all aspects of protein chemistry, including purification/express... proteomics, modeling and structural determination and design. Chapters in this new release include Therapeutic insight into the role of nuclear protein HNF4α in liver carcinogenesis, Structural mechanism of nucleoporins in cancer disease, Identification of nuclear matrix proteins (novel genes) in bladder cancer using Bioinformatic approaches, A comparative study of nuclear proteins of different cancers - A systematic review, Role of lamins in cellular physiology and cancer, and much more.Other chapters cover Nuclear Hormone Receptors as Drug Targets: Advancements and Future Prospects, Proteins binding to tandemly repeated DNA: familiar strangers, HMGB1, R-loops and genome stability, Nuclear tau accumulation in Alzheimer's Disease, and Histone deacetylase's (HDACs) regulates Tau function in Alzheimer's Disease.

  • Profiles of Drug Substances, Excipients, and Related Methodology

    • 1st Edition
    • Volume 50
    • English
    Profiles of Drug Substances, Excipients, and Related Methodology, Volume 50 includes comprehensive profiles of four drug compounds: Sofosbuvir, Nateglinide, Linagliptin, and Dronedarone, providing comprehensive knowledge on their physical and chemical properties, synthesis and degradation pathways, analytical techniques for identification and quantification, separation methods, and pharmacology of drug substances. Finally, this volume includes a review article related to the Applications of Cyclodextrins in Pharmaceutical and Related Fields, along with a chapter on Fenamates Degradation. This information is highly valuable to professionals in the field, but having it all in one place is a great benefit to readers.The Profiles series encompasses five review articles and database compilations on various topics, including the physical profiles, analytical profiles, ADME profiles, methodologies related to the characterization, and methods of chemical synthesis of drug substances and excipients.

  • Coffee

    • 1st Edition
    • Volume 114
    • English
    Coffee, Volume 112 gives the latest updates on one of the premier global traded commodities. With its annual income of approx. USD 200 billion, it supports the livelihoods of nearly 25 million smallholder farmers. In this updated edition, chapters cover The history and genetic diversity of arabica coffee, The importance of wild coffee species in a scenario of climate changes, Coffee plant architecture, Water and heat constraints to coffee ecophysiology and production, The impacts of irradiance on coffee growth and ecophysiology in a context of climate changes, Omic technologies contribution to unveil coffee resilience responses to climate changes, and much more.Additional chapters delve into Agroforestry as an alternative management system to improve coffee crop sustainability and bean quality, Could breeding of new arabica coffee varieties be a response to the climate change?, Selection, development, and management of robusta coffee genotypes under a climate change perspective, Grafting coffee for productivity and health during a changing climate, Coffee somatic embryogenesis: advances, limitations, and perspectives for mass propagation, and many other topics.

  • Applications of Biosensors in Healthcare

    Volume 3
    • 1st Edition
    • Md Saquib Hasnain + 2 more
    • English
    Applications of Biosensors in Healthcare: Volume 3 details and explores the various ways biosensors are used in healthcare, disease management, and therapeutic delivery.This is the third volume out of three volumes covering biosensors in healthcare. The volume discusses various types of biosensors and their use in diagnostics, health monitoring, disease detection, and therapeutic delivery. Combined with the Volume 1, Fundamentals of Biosensors in Healthcare, and Volume 2, Applications of Biosensors in Healthcare, the volumes provide a holistic reference source suitable for researchers, graduate students, postgraduates, and industry professionals involved in biosensing, biosensors, and biomedical applications.

  • Carbon Nanotubes in Agriculture

    Specifications and Applications
    • 1st Edition
    • Manzer H. Siddiqui + 2 more
    • English
    Carbon Nanotubes in Agriculture: Specifications and Applications presents overviews the beneficial roles of carbon nano-tubes (CNT) in regulation of seed germination, plant metabolism and their applications in plant stress management. In light of current climate change trends, CNT-assisted crop yield is likely to play a significant role in improving plant health, enhancing root growth, and improved tolerance in plants to a number of abiotic and biotic stresses. Primarily targeted towards scientists and researchers in nanotechnology, nano-agriculture, nanomaterial-assiste... crop improvement, as well as plant stress tolerance, plant biotechnology and crop yield, this book is the first to focus on this important topic.

  • Trichomonas vaginalis

    Pathogenesis, Diagnosis, and Treatment
    • 1st Edition
    • Prashant Khare + 1 more
    • English
    Trichomonas Vaginalis: Pathogenesis, Diagnosis, and Treatment provides up-to-date knowledge about Trichomoniasis, the most prevalent and neglected non-viral sexually transmitted infection that can result in compromised reproductive health. The book discusses its epidemiology, the pathogenesis of disease, the mechanisms involved in the host immune response, clinical manifestations, and its impact on reproductive health. In addition, it also describes the new insights and challenges involved in the identification of promising drug targets and examines current diagnostic tools and therapies against Trichomonas vaginalis infection.In summary, the book provides comprehensive coverage of this neglected protozoan parasite and the sexually transmitted infection it causes. It is a valuable resource to researchers and scientists who are working on male and female reproductive disorders caused by Trichomonas vaginalis.

  • Microbiota-Gut-Brain Axis and CNS Disorders

    Recent Progress and Perspectives
    • 1st Edition
    • Neeraj Mishra + 1 more
    • English
    Microbiota-Gut-Brain Axis and CNS Disorders: Recent Progress and Perspectives on Human Disease summarizes the main findings on gut-brain axis in different types of CNS disorders, providing a complete overview of the field. The content helps unravel the complex interactions of the microbiota-gut-brain... in CNS disorders to pave a better understanding of microbiota-mediated pathogenesis, avenues for noninvasive prognosis, and therapeutic possibilities leveraging microbiota-gut-brain... modulations. Coverage includes the role of the microbiota-gut-brain axis and gut virome on human diseases including Alzheimer’s Disease, Parkinson’s Disease, Huntington’s Disease, Depression and Anxiety, Autism Spectrum Disorder, Multiple Sclerosis, Stroke, and others.This book will satisfy the urgent need for a broader view of the current associations between gut microbiota alterations and development of CNS disorders, including the use of novel therapeutic approaches for restoring the correct intestinal bacteria content. It is the perfect reference for translational and clinical gut and microbiome researchers tackling the challenges of delivering genes and drugs in a more targeted and efficient manner for the treatment of CNS disorders.

  • Biotechnology Applications in Forestry

    Forest Microbiology Volume 4
    • 1st Edition
    • Fred O Asiegbu + 1 more
    • English
    Biotechnology Applications in Forestry: Forest Microbiology, Volume Four in the Forest Microbiology series, is a comprehensive exploration of harnessing the unique attributes of the microbes in the forest biome and their tree hosts. The book introduces the basics of genomics, applied bioinformatics and next generation sequencing, providing a firm foundation before moving to specific approach, application and use chapters. Further sections explore opportunities through the use of genetics to expand or improve on many of these positive attributes of forest trees and associated organisms, including adaptation to climate change as well as resilience to biotic and abiotic stressors.Novel techniques and current advances in the application of modern biotechniques in tree health protection, mushroom technology, biological control, biochar, bioenergy, Isolate & strain selection, metabolic engineering and commercial application relevant for forest ecosystem are also addressed.

  • Brewing Microbiology

    Managing Microbes, Ensuring Quality and Valorising Waste
    • 2nd Edition
    • Annie Hill
    • English
    Brewing Microbiology: Managing Microbes, Ensuring Quality and Valorising Waste, Second Edition covers micro-organisms of significance to the brewing industry, including the most recent threats to beer quality and stability that have emerged. Reflecting the significant surge in production of no- and low-alcohol (NOLO) beers and Hard Seltzers since the publication of the 1st edition, and the lack of information available on the increased microbiological risk associated with these beverages – and how to control them, a new chapter "Maintaining microbiological quality control in Hard Seltzers and NOLO beverages" provides best practices in ensuring safe and effective management in production and stability. Sustainability and the environment have been at the forefront of brewers strategic thinking for many years. The first edition of Brewing Microbiology included coverage of anaerobic treatments of brewery waste and waste-water treatment. This section has been expanded to cover recent innovations in the valorization of brewery waste streams, such as biotransformation of brewers spent grains.

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