
Advances in Clinical Chemistry
- 1st Edition, Volume 120 - May 16, 2024
- Imprint: Academic Press
- Editor: Gregory S. Makowski
- Language: English
- Hardback ISBN:9 7 8 - 0 - 4 4 3 - 2 9 7 0 0 - 7
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 2 9 7 0 1 - 4
Advances in Clinical Chemistry, Volume 120, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scient… Read more

Purchase options

Institutional subscription on ScienceDirect
Request a sales quote- Provides the most up-to-date technologies in clinical chemistry and clinical laboratory science
- Authored by world renowned clinical laboratory scientists, physicians, and research scientists
- Presents the international benchmark for novel analytical approaches in the clinical laboratory
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Preface
- Chapter One: Biochemical diagnosis of congenital disorders of glycosylation
- Abstract
- Abbreviations
- 1 Introduction
- 2 Fundamentals of glycosylation and related congenital disorders
- 3 Current CDG biomarkers and related laboratory techniques
- 4 Emerging approaches as sources of new or more informative CDG biomarkers
- Summary and perspectives
- Acknowledgment
- References
- Chapter Two: Autoantibody evaluation in idiopathic inflammatory myopathies
- Abstract
- 1 Introduction
- 2 Autoantibodies and the categorization of IIM
- 3 Anti-synthetase syndrome
- 4 Dermatomyositis
- 5 Immune-mediated necrotizing myopathy
- 6 Inclusion body myositis
- 7 Overlap myositis
- 8 Laboratory evaluation of MSAs and MAAs
- 9 Challenges of myositis antibody testing
- 10 Conclusion and future directions
- References
- Chapter Three: Tear biomarkers
- Abstract
- 1 Introduction
- 2 Tear fluid composition
- 3 Tear collection
- 4 Variability factors
- 5 Biomarkers of ocular discomfort
- 6 Biomarkers of ocular diseases
- 7 Biomarkers of systemic diseases
- 8 Concluding remarks
- References
- Chapter Four: Fibrinogen: Structure, abnormalities and laboratory assays
- Abstract
- Abbreviations
- 1 Introduction
- 2 Fibrinogen structure and synthesis
- 3 Fibrinogen metabolism
- 4 Biologic activity
- 5 Fibrinogen disorders
- 6 Fibrinogen measurement
- 7 Conclusion
- References
- Further reading
- Chapter Five: Advances in periodontal biomarkers
- Abstract
- 1 Periodontium and periodontal diseases
- 2 Traditional diagnosis of healthy and diseased periodontium
- 3 Biomarker research in periodontology: background, aim and limitations
- 4 Biologic samples in detection of periodontal biomarkers
- 5 Biomarkers of periodontal health and disease: evidence from systematic reviews and meta-analyses
- 6 Future prospects
- References
- Chapter Six: Molecular tools to regulate gene expression in Trypanosoma cruzi
- Abstract
- 1 Introduction
- 2 Genetic tools applicable to Trypanosoma cruzi
- 3 Gene expression manipulation, biomarkers and new drug targets
- 4 Summary and perspectives
- Acknowledgment
- References
- Index
- Edition: 1
- Volume: 120
- Published: May 16, 2024
- No. of pages (Hardback): 208
- No. of pages (eBook): 232
- Imprint: Academic Press
- Language: English
- Hardback ISBN: 9780443297007
- eBook ISBN: 9780443297014
GM
Gregory S. Makowski
Dr Gregory S Makowski is a board-certified clinical chemist and fellow of the National Academy of Clinical Biochemistry. Following receipt of his PhD in Biochemistry from the University of Connecticut Storrs, he pursued post-doctoral studies at the University of Connecticut School of Medicine in Farmington that culminated in joint appointments in the School of Medicine and the Department of Laboratory Medicine at John Dempsey Hospital. He has numerous clinical and basic science publications and serves on various scientific and editorial boards. He is actively engaged in the training of Pathology residents and fellows in the Department of Pathology and Laboratory Medicine at Hartford Hospital. He currently serves as Vice President Clinical Laboratory Services Hartford HealthCare in Connecticut.