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Elsevier

Books in Life sciences

  • Trace Amines and Neurological Disorders

    Potential Mechanisms and Risk Factors
    • 1st Edition
    • Tahira Farooqui + 1 more
    • English
    Trace Amines and Neurological Disorders: Potential Mechanisms and Risk Factors explores trace amines which, under normal conditions, are present in the mammalian brain and peripheral nervous tissues at very low (nanomolar) concentrations. However, in a diverse array of human pathologies ranging from substance abuse, depression, attention deficit hyperactivity disorder, eating disorders, schizophrenia, and other neurological and neuropsychiatric diseases, the levels of trace amines are unusually high with an imbalance in their functions. Furthermore, the rapid turnover of trace amines is evidenced by their dramatic increases following treatment with monoamine oxidase inhibitors (MAOI) or deletion of the MAO genes. This suggests that the concentration of trace amines may be considerably higher at neuronal synapses than predicted by steady-state measures, implicating some pathophysiological role. Therefore, understanding molecular mechanisms and developing selective agonists and antagonists for trace amine-associated receptors (TAARs) has become a good approach for treating these diseases. Although the effects of trace amines at low physiological concentrations in mammalian species have been difficult to demonstrate, they may serve to maintain the neuronal activity of other monoamine neurotransmitters by possessing postsynaptic modulatory effects, particularly dopamine and serotonin, within defined physiological limits. Such an effect of trace amines makes them ideal candidates for the development of novel therapeutics for a wide range of human disorders. This book presents up-to-date, cutting-edge, and comprehensive information on the link between trace amines and neurological disorders.

  • Neuroimaging, Part I

    • 1st Edition
    • Volume 135
    • English
    Neuroimaging, Part One, a text from The Handbook of Clinical Neurology illustrates how neuroimaging is rapidly expanding its reach and applications in clinical neurology. It is an ideal resource for anyone interested in the study of the nervous system, and is useful to both beginners in various related fields and to specialists who want to update or refresh their knowledge base on neuroimaging. This first volume specifically covers a description of imaging techniques used in the adult brain, aiming to bring a comprehensive view of the field of neuroimaging to a varying audience. It brings broad coverage of the topic using many color images to illustrate key points. Contributions from leading global experts are collated, providing the broadest view of neuroimaging as it currently stands. For a number of neurological disorders, imaging is not only critical for diagnosis, but also for monitoring the effect of therapies, and the entire field is moving from curing diseases to preventing them. Most of the information contained in this volume reflects the newness of this approach, pointing to this new horizon in the study of neurological disorders.

  • Neuroimaging, Part II

    • 1st Edition
    • Volume 136
    • English
    Neuroimaging, Part Two, a volume in The Handbook of Clinical Neurology series, illustrates how neuroimaging is rapidly expanding its reach and applications in clinical neurology. It is an ideal resource for anyone interested in the study of the nervous system, and is useful to both beginners in various related fields and to specialists who want to update or refresh their knowledge base on neuroimaging. This second volume covers imaging of the adult spine and peripheral nervous system, as well as pediatric neuroimaging. In addition, it provides an overview of the differential diagnosis of the most common imaging findings, such as ring enhancement on MRI, and a review of the indications for imaging in the most frequent neurological syndromes. The volume concludes with a review of neuroimaging in experimental animals and how it relates to neuropathology. It brings broad coverage of the topic using many color images to illustrate key points. Contributions from leading global experts are collated, providing the broadest view of neuroimaging as it currently stands. For a number of neurological disorders, imaging is not only critical for diagnosis, but also for monitoring the effect of therapies, with the entire field moving from curing diseases to preventing them. Most of the information contained in this volume reflects the newness of this approach, pointing to the new horizon in the study of neurological disorders.

  • Aquaculture Virology

    • 1st Edition
    • Frederick S.B. Kibenge + 1 more
    • English
    To date textbooks on viruses infecting fish, crustaceans and molluscs, the three main aquatic animal farmed groups, have been on the whole “diseases-centric” and individual viral diseases selected based on “epizoo-centric” approaches with little to no coverage of the basic biology of the viruses, in contrast to textbooks on viruses infecting terrestrial – farmed, pet, and free-range (wild) – animals and humans. Despite considerable advances in animal virology in recent years coupled with an economically important global aquaculture industry, knowledge of viruses of animal aquaculture is still sparse and in some cases outdated although these viruses are closely related to well-known virus families. The last book in fish virology (Fish viruses and fish viral diseases 1988, Wolf, K.) was published in the 1980s. A lot of work has been done on fish viruses and many new aquatic animal viruses continue to be discovered. Aquaculture Virology provides the current state of knowledge of aquatic animal viruses within the current virus classification and taxonomic context thereby allowing the reader to draw on the principles of general virology. This book is a systematic and concise resource useful to anyone involved with or looking to move into aquaculture and fisheries. Clinical veterinarians, aquaculture disease practitioners, biologists, farmers, and all those in industry, government or academia who are interested in aquatic animal virology will find this book extremely useful.

  • Synthetic Biology and Metabolic Engineering in Plants and Microbes Part A: Metabolism in Microbes

    • 1st Edition
    • Volume 575
    • English
    Synthetic Biology and Metabolic Engineering in Plants and Microbes: Part A, the new volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods, synthetic biology, and metabolic engineering in plants and microbes, and includes sections on such topics as the uses of integrases in microbial engineering, biosynthesis, and engineering of tryptophan derived metabolites, regulation and discovery of fungal natural products, and elucidation and localization of plant pathways.

  • Batters and Breadings in Food Processing

    • 2nd Edition
    • Karel Kulp
    • English
    For the first major update of this topic in 21 years, editors Kulp, Loewe, Lorenz, and Gelroth have gathered an elite group of internationally recognized experts. This new edition examines the current market trends and applications for coated food products. It updates our knowledge of ingredient utilization in battered and breaded products using corn, wheat, rice, fats and oils, and flavorings and seasonings. It applies the functionality of these ingredients across the rheology of coating systems and into the selection of specific processing equipment Each chapter explores a different facet of developing batter-based coatings and breadings for a variety of new products, and explains how new technology has turned this profitable food category into a science. New authors have contributed chapters on heat and mass transfer in foods during deep-fat frying, nutritional aspects of coated foods, and food allergens. Batters and Breadings in Food Processing, Second Edition presents essential technical and scientific information in a peer-reviewed resource. It will be valuable reference for food technologists in Research and Development, Quality Assurance, Rheology, and Bakiing. It will make an excellent text for any course with a batters and breadings processing component.

  • Steamed Breads

    Ingredients, Processing and Quality
    • 1st Edition
    • Sidi Huang + 1 more
    • English
    Steamed Breads: Ingredients, Processing, and Quality provides an overview of all aspects of steamed bread and steamed bun technology. A valuable resource for those interested in the practical, technical, scientific, and historical aspects of the subject. Topics that are covered include classification of the different types of steamed bread, flour quality requirements, ingredients, traditional and modern production methods, bread faults and solutions, storage, food safety, nutrition, and future trends. Steamed bread and filled steamed buns or mantou are the staple food in the wheat growing areas of China. Around 50% of all flour consumed in China is used to produce steamed breads. They have recently spread to other Asian countries and are now eaten around the world. The current state of relevant research knowledge about steamed bread in Asia and throughout the world is described. The first comprehensive reference on the topic, Steamed Breads provides a complete overview of this important wheat-based Asian food of value to cereal scientists and researchers, wheat marketers and breeders, and Asian food and steamed bread manufacturers.

  • The Neurobiology of Schizophrenia

    • 1st Edition
    • Ted Abel + 1 more
    • English
    The Neurobiology of Schizophrenia begins with an overview of the various facets and levels of schizophrenia pathophysiology, ranging systematically from its genetic basis over changes in neurochemistry and electrophysiology to a systemic neural circuits level. When possible, the editors point out connections between the various systems. The editors also depict methods and research strategies used in the respective field. The individual backgrounds of the two editors promote a synthesis between basic neuroscience and clinical relevance.

  • Evaluation of Novel Protein Products

    Proceedings of the International Biological Programme (IBP) and Wenner-Gren Center Symposium Held in Stockholm, September 1968
    • 1st Edition
    • A. E. Bender + 2 more
    • English
    Evaluation of Novel Protein Products is a collection of several scientific essays that resulted from a symposium held in Stockholm. The order in which the essays are arranged follows a session type format. Session 1 focuses on the world food problem and the treatment of the nutrition problems in the field of economics, and then ends with the strategy in the examination of unique protein foods. Session 2 of the book is about the unique sources of protein. Possible sources include oilseed, fish, animal husbandry, cereal varieties, and leaf proteins. Sessions 3 to 6 analyze the nutritional value and quality of the said protein sources. Session 7 contains the closing statement about the challenge of protein-calorie malnutrition. Doctors, economists, as well as academic and research students whose focus of study is on food shortage and impact of protein in the human food consumption will find this book invaluable.

  • Oats

    Chemistry and Technology
    • 2nd Edition
    • Francis Webster
    • English
    For the first major update of this topic in 21 years, editors Webster and Wood have gathered an elite group of internationally recognized experts. This new edition addresses all aspects of oat chemistry, processing, nutrition, and plant genetics. It reflects the considerable changes in the science and food uses of oats that have occurred during the last two decades. Each chapter presents an in-depth review of a specific research area complete with an extensive bibliography. The book provides an important summary of oat nutritional research and associated health claims that have been granted in recognition of the nutritional benefits associated with oat consumption. The individual chapters on component chemistry and functionality provide an excellent resource for product developers in their quest to design new, healthy, oat-based food products. The chapters on oat molecular biology and oat breeding coupled with the extensive works on oat nutrition provide direction to researchers interested in developing oats with enhanced nutrition. Oats: Chemistry and Technology, Second Edition, is the only up-to-date review of oat chemistry and technology and will be a valuable resource for food science professionals including nutritionists, cereal chemists, plant biochemists, plant breeders, molecular biologists, grain millers, and product development and research scientists. Improve Your Knowledge About This Super Grain Covers all areas of oat technology - Single source provides in-depth review of all aspects of oat technology.Provides an excellent source of oat nutritional information - Includes details of oat nutritional studies and potential health claims with a special emphasis on β-glucans.Offers authoritative descriptions of oat composition and functional properties - Provides researchers and food scientists with key chemical and application information.Highligh... oat improvement opportunities - Breeding and molecular information provides researchers direction on oat improvement opportunities.Update... our knowledge of oat-processing technology - Provides in-depth discussion of oat milling and oat fractionation.Demyst... oat phenolics - Provides a peer-reviewed, in-depth discussion of oat phenolic chemistry and functional attributes.

  • Stream Ecosystems in a Changing Environment

    • 1st Edition
    • Jeremy B. Jones + 1 more
    • English
    Stream Ecosystems in a Changing Environment synthesizes the current understanding of stream ecosystem ecology, emphasizing nutrient cycling and carbon dynamics, and providing a forward-looking perspective regarding the response of stream ecosystems to environmental change. Each chapter includes a section focusing on anticipated and ongoing dynamics in stream ecosystems in a changing environment, along with hypotheses regarding controls on stream ecosystem functioning. The book, with its innovative sections, provides a bridge between papers published in peer-reviewed scientific journals and the findings of researchers in new areas of study.

  • Lactose-Derived Prebiotics

    A Process Perspective
    • 1st Edition
    • Andrés Illanes + 5 more
    • English
    Lactose-Derived Prebiotics: A Process Perspective is the first scientific reference to provide a comprehensive technological overview of the processes to derive oligosaccharides from dairy for use in functional foods. With their combined 90+ years in industry and research, the authors present the functional properties of prebiotics derived from lactose and the production technology required to make them. The book focuses on process engineering and includes an overview of green chemistry processes involving enzyme biocatalysis, providing detailed coverage of the use of whey lactose as raw material for producing oligosaccharides. The book’s focus on processes and products allows the reader to understand the constraints and impacts of technology on lactose-derived prebiotics.

  • Comprehensive Utilization of Citrus By-Products

    • 1st Edition
    • Yang Shan
    • English
    Comprehensive Utilization of Citrus By-products provides comprehensive knowledge and information on the development and utilization of citrus by-products, including the types, preparation, and determination of their main functional components. As one of the most popular fruits in the world, the processing of citrus fruits produces a great deal of citrus peel, a primary by-product. Current treatments of citrus peel pollute the environment and waste resources so eco-friendly solutions are sought. This book reflects research, trends and attitudes in the field, presenting a wide overview including extraction processes for functional components; isolation and structural identification; synthesis of new compounds; and the research and development of citrus by-products, their biodegradable transformation, and processing equipment. This valuable reference book can be used by scientists, scholars, and students working on citrus, dietitians and nutritionists, citrus processing enterprises, and farmers from cooperative organizations related to citrus processing.

  • Astrocytes and Epilepsy

    • 1st Edition
    • Jacqueline A. Hubbard + 1 more
    • English
    Epilepsy is a devastating group of neurological disorders characterized by periodic and unpredictable seizure activity in the brain. There is a critical need for new drugs and approaches given than at least one-third of all epilepsy patients are not made free of seizures by existing medications and become "medically refractory". Much of epilepsy research has focused on neuronal therapeutic targets, but current antiepileptic drugs often cause severe cognitive, developmental, and behavioral side effects. Recent findings indicate a critical contribution of astrocytes, star-shaped glial cells in the brain, to neuronal and network excitability and seizure activity. Furthermore, many important cellular and molecular changes occur in astrocytes in epileptic tissue in both humans and animal models of epilepsy. The goal of Astrocytes and Epilepsy is to comprehensively review exciting findings linking changes in astrocytes to functional changes responsible for epilepsy for the first time in book format. These insights into astrocyte contribution to seizure susceptibility indicate that astrocytes may represent an important new therapeutic target in the control of epilepsy. Astrocytes and Epilepsy includes background explanatory text on astrocyte morphology and physiology, epilepsy models and syndromes, and evidence from both human tissue studies and animal models linking functional changes in astrocytes to epilepsy. Beautifully labelled diagrams are presented and relevant figures from the literature are reproduced to elucidate key findings and concepts in this rapidly emerging field. Astrocytes and Epilepsy is written for neuroscientists, epilepsy researchers, astrocyte investigators as well as neurologists and other specialists caring for patients with epilepsy.

  • Refining of Oils and Fats for Edible Purposes

    • 2nd Edition
    • A. J. C. Andersen
    • P. N. Williams
    • English
    Refining of Oils and Fats for Edible Purposes, Second Revised Edition details the processes and treatments of crude (plant- and animal-based) oils and fats to render them fit for human consumption. The book is composed of five chapters. The first two chapters provide the methods in refining fat-insoluble and fat-soluble impurities. The third chapter presents techniques to minimize the shrinkage of crude fat and oils entering the process and increase production output. Chapter 4 considers refinery plant design based on the kinds of fats to be processed, kinds of processes to be implemented and projected output. The last chapter presents statistical data of oil and fat consumption from selected countries. Industrial engineers, production managers, chemists, plant designers, and students will find the book a good source of information.

  • Margarine

    • 2nd Edition
    • A.J.C. Andersen + 1 more
    • English
    Margarine, Second Revised Edition provides a comprehensive exposition of the chemistry, production, and nutritional aspects of margarine. The book surveys the invention of margarine and the development of the margarine industry, as well as its nutritional and statistical features. The raw materials, ingredients, and chemical nature of fats and oils needed for production are presented; the step-by-step processing and the biochemical interactions are described in detail; and the bacteriological processes during the preparation of milk and storage and preservation are discussed. This edition contains new information but still retains the general layout of the first edition. Food technologists, chemists, production engineers, and those curious about the production of margarine will find this book interesting.

  • Methods in Neurosciences

    Quantitative and Qualitative Microscopy
    • 1st Edition
    • Volume 3
    • P. Michael Conn
    • English
    Because of the significance of morphology and cellular communication unique to the functioning and interdependence of neural systems, many of the advances in the neurosciences rely on classic as well as new microscopy techniques.

  • Electrophysiology and Microinjection

    • 1st Edition
    • Volume 4
    • P. Michael Conn
    • English
    Electrical activity is central to the functioning and nature of neural cells. Every effort has been made in this volume to provide representative examples of useful techniques that have made this area a productive component of the neurosciences.

  • L'enfant dyspraxique et les apprentissages

    Coordonner les actions thérapeutiques et scolaires
    • 2nd Edition
    • Michèle Mazeau + 2 more
    • French
    Au sein des « dys- », les dyspraxies sont des troubles du développement gestuel et/ou visuo-spatial dont les répercussions sociales et scolaires peuvent être sévères, envahissant le quotidien et compromettant l’avenir. Ces pathologies ont en effet de graves conséquences sur l’ensemble des apprentissages.L’ouv... par des cliniciennes dont la pratique auprès de jeunes dyspraxiques s’inscrit dans l’indispensable interaction quotidienne entre rééducation et école, cet ouvrage vise à fournir des clés pour comprendre les ressorts cachés de ces échecs scolaires, afin de mieux les prévenir ou tout au moins les pallier. C’est pourquoi sont abordés ici à la fois les stratégies de remédiation (dévolues aux rééducateurs) et les aménagements qui, dans le même temps, doivent prendre place en classe, en partenariat avec les enseignants. Comportant de nombreux exemples qui illustrent les difficultés rencontrées tous les jours par ces enfants, ce livre constitue un ensemble cohérent de propositions pratiques et concrètes visant à rétablir les chances de réussite scolaire et d’épanouissement du jeune dyspraxique.Cet ouvrage permet non seulement de comprendre la spécificité des processus en jeu dans les apprentissages du jeune dyspraxique (gestuels, scolaires ou rééducatifs), mais il constitue un outil de terrain précieux pour assurer la réussite scolaire et l’épanouissement du jeune dyspraxique. Les auteures précisent les conditions d’un véritable projet thérapeutique global, avant d’aborder les différents aspects des accompagnements dans les apprentissages : écrire, e-écrire, compter, lire. Puis un chapitre de synthèse offre une méthode générale d’analyse des supports scolaires, spécifiquement dans les aspects qui croisent et sollicitent le handicap de l’élève. Enfin, sont abordées les difficultés liées à la vie quotidienne (repas, habillage, sports et loisirs) et leurs répercussions sur l’estime de soi. Cette nouvelle édition propose une révision de l’ensemble des données et une refonte complète des chapitres dédiés aux supports pédagogiques et à l’informatique qui ont considérablement évolué.

  • Innovative Food Processing Technologies

    Extraction, Separation, Component Modification and Process Intensification
    • 1st Edition
    • Kai Knoerzer + 2 more
    • English
    Innovative Food Processing Technologies: Extraction, Separation, Component Modification and Process Intensification focuses on advances in new and novel non-thermal processing technologies which allow food producers to modify and process food with minimal damage to the foodstuffs. The book is highly focused on the application of new and novel technologies, beginning with an introductory chapter, and then detailing technologies which can be used to extract food components. Further sections on the use of technologies to modify the structure of food and the separation of food components are also included, with a final section focusing on process intensification and enhancement.

  • Statistical Aspects of the Microbiological Examination of Foods

    • 3rd Edition
    • Basil Jarvis
    • English
    Statistical Aspects of the Microbiological Examination of Foods, Third Edition, updates some important statistical procedures following intensive collaborative work by many experts in microbiology and statistics, and corrects typographic and other errors present in the previous edition. Following a brief introduction to the subject, basic statistical concepts and procedures are described including both theoretical and actual frequency distributions that are associated with the occurrence of microorganisms in foods. This leads into a discussion of the methods for examination of foods and the sources of statistical and practical errors associated with the methods. Such errors are important in understanding the principles of measurement uncertainty as applied to microbiological data and the approaches to determination of uncertainty. The ways in which the concept of statistical process control developed many years ago to improve commercial manufacturing processes can be applied to microbiological examination in the laboratory. This is important in ensuring that laboratory results reflect, as precisely as possible, the microbiological status of manufactured products through the concept and practice of laboratory accreditation and proficiency testing. The use of properly validated standard methods of testing and the verification of ‘in house’ methods against internationally validated methods is of increasing importance in ensuring that laboratory results are meaningful in relation to development of and compliance with established microbiological criteria for foods. The final chapter of the book reviews the uses of such criteria in relation to the development of and compliance with food safety objectives. Throughout the book the theoretical concepts are illustrated in worked examples using real data obtained in the examination of foods and in research studies concerned with food safety.

  • Ubiquitination and Transmembrane Signaling

    • 1st Edition
    • Volume 141
    • English
    Progress in Molecular Biology and Translational Science provides a forum for discussion of new discoveries, approaches, and ideas in molecular biology. It contains contributions from leaders in their fields and abundant references.

  • Enzymes of Epigenetics

    • 1st Edition
    • Volume 573
    • English
    Enzymes of Epigenetics, one of two new volumes in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods that are employed to study epigenetic regulation and includes structural, biochemical, molecular, biological, cellular, computational, and systems approaches. Topics include chromatin structure and histones, posttranslational histone modification enzymes and complexes, histone modification binders, DNA modifications and nucleic acid regulators, epigenetic technologies and small molecule epigenetic regulators, and biological connections

  • Percutaneous Surgery of the Upper Urinary Tract

    Handbook of Endourology
    • 1st Edition
    • Petrisor Aurelian Geavlete
    • English
    Percutaneous Surgery of the Upper Urinary Tract: Handbook of Endourology contains five focused, review-oriented volumes that are ideal for students and clinicians looking for a comprehensive review rather than a whole course. Each volume is easily accessible through eBook format. Topics covered review both the endourological diagnosis and treatment of prostate, urethral, urinary bladder, upper urinary tract, and renal pathology. All chapters describe the most recent techniques, review the latest results, and analyze the most modern technologies. In the past ten years, the field of endourology has expanded beyond the urinary tract to include all urologic minimally invasive surgical procedures. Recent advancements in robotic and laparoscopic bladder surgery make this one of the fastest moving fields in medicine. As current textbooks are too time-consuming for busy urologists or trainees who also need to learn other areas of urology, this collection provides quick references and over 4000 images that are appropriate for fellows as well as those teaching in the field.

  • Insects as Sustainable Food Ingredients

    Production, Processing and Food Applications
    • 1st Edition
    • Aaron T. Dossey + 2 more
    • English
    Insects as Sustainable Food Ingredients: Production, Processing and Food Applications describes how insects can be mass produced and incorporated into our food supply at an industrial and cost-effective scale, providing valuable guidance on how to build the insect-based agriculture and the food and biomaterial industry. Editor Aaron Dossey, a pioneer in the processing of insects for human consumption, brings together a team of international experts who effectively summarize the current state-of-the-art, providing helpful recommendations on which readers can build companies, products, and research programs. Researchers, entrepreneurs, farmers, policymakers, and anyone interested in insect mass production and the industrial use of insects will benefit from the content in this comprehensive reference. The book contains all the information a basic practitioner in the field needs, making this a useful resource for those writing a grant, a research or review article, a press article, or news clip, or for those deciding how to enter the world of insect based food ingredients.

  • The Vaccine Book

    • 2nd Edition
    • Barry R. Bloom + 1 more
    • English
    The Vaccine Book, Second Edition provides comprehensive information on the current and future state of vaccines. It reveals the scientific opportunities and potential impact of vaccines, including economic and ethical challenges, problems encountered when producing vaccines, how clinical vaccine trials are designed, and how to introduce vaccines into widespread use. Although vaccines are now available for many diseases, there are still challenges ahead for major diseases, such as AIDS, tuberculosis, and malaria. This book is designed for students, researchers, public health officials, and all others interested in increasing their understanding of vaccines. It answers common questions regarding the use of vaccines in the context of a rapidly expanding anti-vaccine environment. This new edition is completely updated and revised with new and unique topics, including new vaccines, problems of declining immunization rates, trust in vaccines, the vaccine hesitancy, and the social value of vaccines for the community vs. the individual child’s risk.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 75
    • English
    Advances in Clinical Chemistry, Volume 75, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians, and research scientists. This serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry and is the benchmark for novel analytical approaches in the clinical laboratory.

  • Science of Gluten-Free Foods and Beverages

    • 1st Edition
    • Elke Arendt + 1 more
    • English
    In genetically susceptible individuals, the ingestion of gluten and related proteins triggers an immune-mediated enteropathy known as celiac disease (CD). Recent epidemiological studies have shown that 1 in 100 people worldwide suffers from CD—a rate that establishes CD as one of the most common food intolerances. CD patients that eat wheat or related proteins, such as hordeins (barley) and secalins (rye), undergo an immunological response, localized in the small intestine, that destroys mature absorptive epithelial cells on the surface of the small intestine. Currently, the only way to treat CD is the total life-long avoidance of gluten ingestion. Therefore, people that have CD must follow a very strict diet and avoid products that contain wheat, rye, and barley. Avoiding cereals leads to a recovery from the disease and significant improvement of the intestinal mucosa and its absorptive functions. Celiac patients are not in the position to eat some of the most common foods, such as breads, pizzas, and biscuits, or to drink beer and whiskey. Because of the unique properties of gluten, producing good-quality gluten-free products is a big challenge for scientists. Science of Gluten-Free Foods and Beverages covers the work presented at the First International Conference on Gluten-Free Cereal Products and Beverages. The area of gluten-free foods and beverages is becoming more and more important, since the number of people with CD and gluten allergies is rising. In the United Kingdom, 10% of the population claims to have food allergies. This book will be extensively referenced. It is meant to give an overview of the work being carried out in the area of gluten-free science.

  • Smart Bandage Technologies

    Design and Application
    • 1st Edition
    • James Davis
    • English
    Smart Bandage Technology: Design and Application is a guide to the integration of sensors and electronic systems into bandages for the application of wound management. Davis provides a comprehensive guide to the design and development of functional material for wound management for engineers of all levels possessing core knowledge in chemistry, biochemistry, and materials science. Includes an introduction to the design of advanced wound care technologies for undergraduate engineers, as well as a coherent exploration of competing technologies suitable for postgraduate and postdoctoral researchers. Each section provides a high level overview of the concepts and techniques involved in developing smart bandages, including their manufacturing, operation, and implementation, and also exposes and explores the most recent approaches to wound care in more detail. This book incorporates contextual boxes to provide a greater degree of detail to examples given and also includes an extensive bibliography for those seeking to research further on the various topics discussed.

  • Protein Physics

    A Course of Lectures
    • 2nd Edition
    • Alexei V. Finkelstein + 1 more
    • English
    Protein Physics: A Course of Lectures covers the most general problems of protein structure, folding and function. It describes key experimental facts and introduces concepts and theories, dealing with fibrous, membrane, and water-soluble globular proteins, in both their native and denatured states. The book systematically summarizes and presents the results of several decades of worldwide fundamental research on protein physics, structure, and folding, describing many physical models that help readers make estimates and predictions of physical processes that occur in proteins. New to this revised edition is the inclusion of novel information on amyloid aggregation, natively disordered proteins, protein folding in vivo, protein motors, misfolding, chameleon proteins, advances in protein engineering & design, and advances in the modeling of protein folding. Further, the book provides problems with solutions, many new and updated references, and physical and mathematical appendices. In addition, new figures (including stereo drawings, with a special appendix showing how to use them) are added, making this an ideal resource for graduate and advanced undergraduate students and researchers in academia in the fields of biophysics, physics, biochemistry, biologists, biotechnology, and chemistry.

  • Mathematical Biology

    A Conference on Theoretical Aspects of Molecular Science
    • 1st Edition
    • T. A. Burton
    • English
    Mathematical Biology: A Conference on Theoretical Aspects of Molecular Science is a collection of papers that covers various investigations in mathematical biology. The text tackles a wide range of topics, from biological equation models up to electrical phenomena in biological systems. The coverage of the text includes existence of a periodic solution for a two predator-one prey ecosystem modeled on a chemostat; mathematical treatment of nerve conduction and cardiac purkinje fibers; and models of positional information. The book will be of great interest to students, researchers, and practitioners of biological sciences.

  • Kiwifruit

    The Genus ACTINIDIA
    • 1st Edition
    • Hongwen Huang
    • English
    Kiwifruit: The Genus ACTINIDIA includes extensive and full coverage of scientific and applied information, ranging from basic taxonomy, population genetics, and natural resources/distributi... to domestication history and breeding/cultivars, also including further information on culture and international production and commercialization. The book gathers information not previously available in the English language, providing an authoritative reference for professionals, including taxonomists, horticulturist, breeders, conservationists, kiwifruit technicians, college teachers, policymakers in the industry, and governments. In addition to those in the academic and professional sectors, horticultural and botanical enthusiasts will find the information presented highly accessible.

  • The Microbiology of Respiratory System Infections

    • 1st Edition
    • Volume 1
    • Kateryna Kon + 1 more
    • English
    The Microbiology of Respiratory System Infections reviews modern approaches in the diagnosis, treatment, and prophylaxis of respiratory system infections. The book is very useful for researchers, scientists, academics, medical practitioners, graduate and postgraduate students, and specialists from pharmaceutical and laboratory diagnostic companies. The book has been divided into three sections according to the types of respiratory pathogens. The first section contains reviews on the most common and epidemiologically important respiratory viruses, such as influenza virus, severe acute respiratory system coronavirus, and recently discovered Middle East respiratory syndrome coronavirus. The second section is devoted to bacterial and fungal pathogens, which discusses etiology and pathogenesis including infections in patients with compromised immune system, and infections caused by fungal pathogens, such as Aspergillus and Pneumocystis. The third section incorporates treatment approaches against different types of bacterial infections of the lower respiratory tract. This section reviews classical antimicrobial and phytomedical approaches as well as the application of nanotechnology against respiratory pathogens.

  • The Mathematical Brain Across the Lifespan

    • 1st Edition
    • Volume 227
    • English
    The Mathematical Brain Across the Lifespan is the latest volume in the Progress in Brain Research series that focuses on new trends and developments. This established international series examines major areas of basic and clinical research within the neurosciences, as well as popular and emerging subfields.

  • Advances in Food Traceability Techniques and Technologies

    Improving Quality Throughout the Food Chain
    • 1st Edition
    • Montserrat Espiñeira + 1 more
    • English
    Advances in Food Traceability Techniques and Technologies: Improving Quality Throughout the Food Chain covers in detail a topic of great importance to both the food industry which is obliged to provide clear and accurate labeling of their products and the government and other organizations which are tasked with verification of claims of food quality and safety. The traceability of food products is becoming ever more important as globalization continues to increase the complexity of food chains. Coverage in the book includes the wide range of technologies and techniques which have been utilized in the tracing of food products. In addition, the ways in which the misuse of food traceability will affect the quality of food is also covered throughout. The first part of the book introduces the concept of traceability in the food industry, highlighting advantages of a robust traceability and the difficulties involved in implementing them. The second part looks at the technologies used to trace products, and the third section reviews the legal requirements for food traceability in the EU, the US, and the rest of the world. The final section contains a number of case studies which evaluate how food traceability has been successfully implemented in various foods focusing on the quality of the food.

  • Antiphospholipid Syndrome in Systemic Autoimmune Diseases

    • 2nd Edition
    • Volume 12
    • R. Cervera + 3 more
    • English
    Antiphospholipid Syndrome in Systemic Autoimmune Diseases, Second Edition provides an overview of our current understanding of this major disease. It includes the latest information on the new pathogenetic mechanisms involved, along with clinical manifestations in both the thrombotic and non-thrombotic manifestations of this important disease. Antiphospholipid syndrome is an autoimmune disease that causes abnormal blood clots. It is now recognized as a major cause of common conditions, including stroke, heart attack, miscarriage, epilepsy, and memory loss, and as such is gaining recognition in all branches of medicine, from obstetrics to cardiology, and from psychiatry to orthopedics.

  • Neurobiology of Epilepsy

    From Genes to Networks
    • 1st Edition
    • Volume 226
    • English
    Neurobiology of Epilepsy: From Genes to Networks is the latest volume in the Progress in Brain Research series that focuses on new trends and developments. This established international series examines major areas of basic and clinical research within the neurosciences, as well as popular and emerging subfields.

  • Sport and Exercise Psychology Research

    From Theory to Practice
    • 1st Edition
    • Markus Raab + 4 more
    • English
    Sport and Exercise Psychology Research: From Theory to Practice provides a comprehensive summary of new research in sport and exercise psychology from worldwide researchers. Encompassing theory, research, and applications, the book is split into several themed sections. Section 1 discusses basic antecedents to performance including fitness, practice, emotion, team dynamics, and more. Section 2 identifies factors influencing individual performance. Section 3 discusses applied sport psychology for athletes and coaches, and section 4 includes approaches from exercise psychology on motivation and well-being. The book includes a mix of award winning researchers from the European Sport Psychology Association, along with top researchers from the U.S. to bring an international overview to sport psychology.

  • Informed and Healthy

    Theoretical and Applied Perspectives on the Value of Information to Health Care
    • 1st Edition
    • Maria G. N. Musoke
    • English
    Informed and Healthy: Theoretical and Applied Perspectives on the Value of Information to Health Care focuses on two major issues: the value attributed to information by users and its effect on health care; and, a new model of information behavior in which the value of information drives various information activities (unlike many information models which tend to give prominence to information needs). The inductive development of the model is explained, with associated implications for theory and transferability or applicability elsewhere. The book uses a case study of the health information system in Uganda and expands the analysis by comparing it to other systems utilized by different countries in diverse levels of development. Topics such as access and use of information; value attribution and effect on health outcomes; and modelling information behavior and its implications on health informatics are discussed in detail. This book is a valuable resource for health professionals, planners, and policy makers, as well as researchers interested in health information systems and their applicability in different environments.

  • Fungal Toxins

    A Comprehensive Treatise
    • 1st Edition
    • Alex Ciegler + 2 more
    • English
    Microbial Toxins, Volume VI: Fungal Toxins covers information on the evaluation of the chemical, biological, and biomedical aspects of the fungal toxins. The book discusses the historical structure chemistry, production, analysis, detoxification, biosynthesis, pharmacology, toxicology, and molecular biochemistry of aflatoxins and related compounds. The text also describes the isolation, analysis, production, chemistry, biological effects, and biogenesis of the ochratoxins, as well as the bioproduction, biosynthesis, and chemical properties of misclellaneous Aspergillus toxins. Various species of storage fungi, including yellowed rice toxins, luteoskyrin and related compounds, chlorine-containing compounds, citrinin, and citreoviridin are also considered. The book further tackles the physical and chemical properties and the biological activity of the rubratoxins; the biosynthesis and biochemical effects of patulin, penicillic acid, and other carcinogenic lactones; as well as the structure, production, biosynthesis, and biological effects of cyclopiazonic acid and related toxins. The text also encompasses bioproduction, properties, chemical structure, and biological activity of miscellaneous Penicillium toxins. Microbiologists, biochemists, epidemiologists, pharmacologists, toxicologists, medical students and people involved in other related fields will find the book useful.

  • Dynemicin A, Uncialamycin and Analogues

    • 1st Edition
    • Daniel Best + 2 more
    • English
    Enediynes are natural products with highly active cytotoxicity and antibacterial activity, and thus have significant potential in the development of anti-cancer treatments. However, they are not readily available and can degrade rapidly during isolation; one solution is to produce them using total synthesis.Dynemicin A and uncialamycin are two such enediynes, with similar structures, for which total synthesis has been achieved. This book presents the isolation and preparation of these two compounds and their analogues through various synthesis strategies. Details of the structural elements essential to their anti-cancer activity are presented, with the objective of explaining and optimizing their biological activities and potential development as drugs.

  • Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging

    Volume 10
    • 1st Edition
    • M. A. Hayat
    • English
    Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging, Volume 10 offer a valuable guide to both cellular processes, while encouraging researchers to explore their potentially important connections. Autophagy serves to maintain healthy cells, tissues, and organs, but also promotes cancer survival and growth of established tumors. Impaired or deregulated autophagy can also contribute to disease pathogenesis. This is the tenth volume of the multivolume series that discusses, in detail, almost all aspects of the autophagy machinery in the context of health, cancer, and other pathologies. Autophagy maintains homeostasis during starvation or stress conditions by balancing the synthesis of cellular components and their deregulation by autophagy. Volume 10 of the Autophagy series discusses the role of a novel binuclear palladacycle complex that inhibits melanoma growth through apoptosis and autophagy.

  • Antibiotic Resistance

    Mechanisms and New Antimicrobial Approaches
    • 1st Edition
    • Kateryna Kon + 1 more
    • English
    Antibiotic Resistance: Mechanisms and New Antimicrobial Approaches discusses up-to-date knowledge in mechanisms of antibiotic resistance and all recent advances in fighting microbial resistance such as the applications of nanotechnology, plant products, bacteriophages, marine products, algae, insect-derived products, and other alternative methods that can be applied to fight bacterial infections. Understanding fundamental mechanisms of antibiotic resistance is a key step in the discovery of effective methods to cope with resistance. This book also discusses methods used to fight antibiotic-resistant infection based on a deep understanding of the mechanisms involved in the development of the resistance.

  • Bacterial Endotoxins

    A Comprehensive Treatise
    • 1st Edition
    • Solomon Kadis + 2 more
    • English
    Microbial Toxins, Volume V: Bacterial Endotoxins covers the physiology, pathology, and immunology of bacterial endotoxins. The book discusses the relationship of lipopolysaccharide structure to bacterial virulence; the importance of blood-group and Forssman antigenic determinants in interactions between human and microbes; and the chemical modification of endotoxin and inactivation of its biological properties. The text also describes the effects of endotoxic lipopolysaccharides on the complement system; the host-dependent detoxification of bacterial endotoxin; and the metabolic effects of bacterial endotoxins. The release of vasoactive agents and the vascular effects of endotoxin are also considered. The book further tackles the febrile response to endotoxin; some major aspects and the relationship between shock and endotoxemia; as well as the effects of lipopolysaccharides (endotoxins) on the susceptibility to infections. The text also encompasses the role of hypersensitivity and tolerance in reactions to endotoxins. Pathologists, immunologists, physiologists, and microbiologists will find the book invaluable.

  • Introduction to the Principles of Drug Design

    • 1st Edition
    • H. J. Smith + 1 more
    • English
    Introduction to the Principles of Drug Design provides a framework of fundamental drug design and principles into which drugs following on developments may be fitted. This book presents the rationales behind the design of drugs. Organized into nine chapters, this book begins with an overview of how the body handles a drug in terms of absorption, metabolism, distribution, and excretion. This text then examines the critical drug activity at the receptor site, which is usually related to blood and other distribution fluid levels. Other chapters consider the factors involved in binding a drug, metabolite, or substrate to a receptor. The final chapter deals with the design of chemotherapeutic agent for clinical use in the treatment of human infections. This book is intended for use in undergraduate pharmacy courses in medicinal chemistry and as an aid in similar courses in biochemistry and pharmacology. Graduates in chemistry just entering the pharmaceutical industry will also find this book useful.

  • Emulsions

    • 1st Edition
    • Volume 3
    • Alexandru Grumezescu
    • English
    Emulsions, the third volume of the Nanotechnology in the Food Industry series, is an invaluable resource for anyone in the food industry who needs the most recent information about scientific advances in nanotechnology on this topic. This volume focuses on basic and advanced knowledge about nanoemulsion, and presents an overview of the production methods, materials (solvents, emulsifiers, and functional ingredients), and current analytical techniques that can be used for the identification and characterization of nanoemulsions. The book also discusses the applications of nanoemulsion with special emphasis on systems suitable for utilization within the food industry. This book is useful to a wide audience of food science research professionals and students who are doing research in this field, as well as others interested in recent nanotechnological progress worldwide.

  • Artificial Photosynthesis

    • 1st Edition
    • Volume 79
    • English
    Artificial Photosynthesis, the latest edition in the Advances in Botanical Research series, which publishes in-depth and up-to-date reviews on a wide range of topics in the plant sciences features several reviews by recognized experts on all aspects of plant genetics, biochemistry, cell biology, molecular biology, physiology, and ecology.

  • The Zebrafish: Cellular and Developmental Biology, Part B Developmental Biology

    • 4th Edition
    • Volume 134
    • English
    The Zebrafish: Cellular and Developmental Biology, Part B Developmental Biology, the second volume on the topic in the Methods in Cell Biology series, looks at methods for analyzing cellular and developmental biology of zebrafish. Chapters cover such topics as cell biology and developmental and neural biology.

  • Pesticides in the Soil Environment

    • 1st Edition
    • Shahamat U. Khan
    • R. J. Wakeman
    • English
    Fundamental Aspects of Pollution Control and Environmental Science, 5: Pesticides in the Soil Environment focuses on the effects of pesticide use on the quality of soil. The manuscript first offers information on the classification of pesticides and physicochemical processes affecting pesticides in soil. Topics include herbicides, fungicides, movement in soil, chemical conversion and degradation, and photodecomposition. The text then elaborates on microbial processes affecting pesticides in soil, including fumigants, fungicides, and insecticides. The text examines the occurrence and persistence of pesticide residues in soil and minimizing pesticide residues in soil. Discussions focus on persistence, bound residues, plant uptake, short residual residues, and eliminating pesticide residues. The text is a dependable reference for readers interested in the effects of pesticide use on the quality of soil.

  • Bubbles in Food 2

    Novelty, Health and Luxury
    • 1st Edition
    • Grant Campbell
    • English
    Bubbles give novelty and distinctiveness to many food and drink products including the most important and interesting ones such as bread, beer, ice cream, whipped cream, soufflés and champagne. Understanding the creation and control of bubbles in food products is key to the success of the domestic chef or the industrial food manufacturer. This new volume presents the proceedings of the conference Bubbles in Food 2: Novelty, Health and Luxury. This book is fully updated and expanded from the original Bubbles in Food book published in 1999. This new title brings together up-to-date information on the latest developments in this fast moving area. Bubbles in Food 2 includes novel experimental techniques for measuring and quantifying the aerated structure of foods (e.g. ultrasonics, MRI imaging, X-ray tomography, microscopy, rheology, image analysis), and novel analytical approaches for interpreting aerated food properties and behavior. These techniques and approaches provide stimulus for new product development or for enhancing the understanding of the manufacture of existing products, leading to enhanced quality and greater product differentiation. Bubbles in Food 2: Novelty, Health and Luxury aims to enhance the appreciation of aerated foods and to provide stimulation and cross fertilisation of ideas for the exploitation of bubbles as a novel and versatile food ingredient.

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