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Books in Life sciences

  • Stress and The Brain: Evidence from Molecular Mechanisms to Interventions and Therapies

    • 1st Edition
    • Volume 291
    • English
    Stress and The Brain: Evidence from Molecular Mechanisms to Interventions and Therapies is a comprehensive exploration of how stress affects the brain at a molecular level and its broader implications for mental and neurological health. The book delves into the mechanisms by which stress triggers changes in brain function, including the activation of the hypothalamic-pituita... (HPA) axis, synaptic plasticity alterations, oxidative stress, neuroinflammation, and mitochondrial dysfunction. It examines how these molecular processes contribute to conditions such as neurodegeneration, anxiety, depression, and other stress-related disorders. Furthermore, the book provides an in-depth analysis of current therapeutic interventions, both pharmacological and behavioral, as well as natural antidotes that aim to mitigate the adverse effects of stress on the brain. By synthesizing evidence from cutting-edge research, this book offers valuable insights for scientists, clinicians, and mental health professionals seeking to understand and address the complex interplay between stress and brain health.

  • Tumor-Targeting with Stimuli-Responsive Vesicular Nanocarriers

    Basics to Emerging Applications
    • 1st Edition
    • Ankit Jain + 2 more
    • English
    Tumour-Targeting with Stimuli Responsive Vesicular Nanocarriers: Basics to Emerging Applications not only acquaints scientists and science interns with the fundamental knowledge of the experimental aspects and state-of-the-art technology for vesicular carriers to equip their rational application in tumor targeting, but also provides a holistic understanding of regulatory concerns, patents, and clinical trials. In 15 chapters. this book provides basics and advances in stimuli-responsive vesicular carriers for tumor targeting based on findings outlined in highly organized tables, illustrative figures, and flow charts.With a focus on the extrapolation of bioengineering tools in the domain of vesicular carriers, stimuli-responsive features concerning tumors, drug delivery approaches, and associated challenges, it helps readers to define the major gaps in knowledge that can lead to significant scientific discoveries in therapy, diagnosis, and theragnosis of cancer.

  • The Potential of Cancer Biomarkers

    From Discovery to Clinical Application
    • 1st Edition
    • Pranav Kumar Prabhakar
    • English
    The Potential of Biomarkers: From Discovery to Clinical Application addresses the challenges related to knowledge dissemination, interdisciplinary understanding, diagnostic complexity, quality assurance, patient care, research advancement, education, and professional development within the field of clinical biochemistry. The book provides a holistic solution by offering comprehensive insights and practical guidance to a diverse audience, contributing to the enhancement of healthcare and biomedical research. Each chapter explores the multifaceted landscape of biomarker research, offering a wealth of insights and expertise in genomics, proteomics, metabolomics, and more.Cancer biomarkers, the molecular signatures of cancer, hold immense promise in revolutionizing how we diagnose, treat, and personalize therapies for cancer patients. In this curated reference, esteemed contributors explore the multifaceted landscape of biomarker research, offering a wealth of insights and expertise in genomics, proteomics, metabolomics, and more.

  • Terrestrial Biomes

    Global Biome Conservation and Global Warming Impacts on Ecology and Biodiversity
    • 1st Edition
    • Germano Leão Demolin-Leite
    • English
    Terrestrial Biomes: Global Biome Conservation and Global Warming Impacts on Ecology and Biodiversity explores the effects of anthropogenic activities on Earth’s terrestrial biomes, species, and climate. The book summarizes operational and potential monitoring tools to conserve or recover terrestrial biomes at a global scale. Written by international experts in ecology and biodiversity conservation, this book identifies the challenges and threats to terrestrial organisms and connects them to real cases of conservation.This is an important resource for students, professors, researchers, and governmental and non-governmental organizations active in biodiversity conservation and climate change mitigation.

  • The Science of the Brain

    Function, Dysfunction and Disease
    • 1st Edition
    • Ari Rappoport
    • English
    The Science of the Brain: Function, Dysfunction and Disease delves into the intricate workings of the human brain, offering a groundbreaking examination of its complexities and the disorders that can arise when it malfunctions. This book, authored by a distinguished neuroscientist, unravels the mysteries of cognition, memory, and emotion while exploring how neurodegenerative diseases, mental health conditions, and brain injuries disrupt these processes. Designed to be accessible yet deeply informative, it bridges the gap between cutting-edge scientific research and real-world clinical applications, making it an invaluable resource for both professionals and curious readers.In addition to its comprehensive analysis of brain function, the book introduces readers to the latest innovations in neuroscience, including technological advancements in brain imaging and treatments. It also examines the ethical dilemmas posed by emerging technologies and their implications for society. With its blend of readability and scientific rigor, this work sheds light on the possibilities for future research and intervention, inspiring a deeper understanding of one of the most complex organs in the human body.

  • Emerging Fuzzy Intelligent Systems for Smart Healthcare Management

    Applications of Disc q-Rung Orthopair Fuzzy Sets
    • 1st Edition
    • Shahzaib Ashraf + 3 more
    • English
    Emerging Fuzzy Intelligent Systems for Smart Healthcare Management: Applications of Disc q-Rung Orthopair Fuzzy Sets presents comprehensive methodological frameworks and the latest empirical research findings concerning disc q-rung orthopair fuzzy operators, with a specific focus on their applications in smart technologies for healthcare management. The book solves a crucial problem by offering readers an invaluable opportunity to conduct a comparative analysis, contrasting the proposed methods with their existing knowledge base. Disc q-Rung Orthopair sets, being the generalization of q-Rung Orthopair fuzzy sets, which are, in turn, the generalization of Pythagorean fuzzy sets, extend the capabilities of handling uncertainty beyond conventional fuzzy sets.The authors strive to narrow the knowledge gap by clarifying the practical applications of disc q-rung orthopair fuzzy logic. In addition, it explores an enhanced version of q-Rung Orthopair Fuzzy Sets, specifically focusing on Disc q-Rung Orthopair Fuzzy Sets, introducing various types of operators. These operators play a crucial role in solving decision-making and optimization problems. A notable contribution is the development of a hybrid operator, termed as the Disc q-Rung Orthopair Fuzzy Hybrid Weighted Averaging/Geometric (D-qROFHWA/G) operator.

  • Imaging of Neurofluids, An Issue of Neuroimaging Clinics of North America

    • 1st Edition
    • Volume 35-2
    • Nivedita Agarwal + 1 more
    • English
    In this issue of Neuroimaging Clinics, guest editors Drs. Nivedita Agarwal and Anja van der Kolk bring their considerable expertise to the topic of Imaging of Neurofluids. Top experts discuss key topics in this burgeoning field to create a primer ideal for neuroradiologists and radiologists. Topics include the basics of neurofluids, animal models, gadolinium-based imaging, perfusion-based imaging, diffusion tensor imaging, PET imaging, and specific articles on perivascular spaces, parasagittal dura mater and meningeal lymphatics, amyloid-related imaging abnormalities, and Alzheimer’s disease.

  • Adenoviral Vectors for Gene Therapy

    • 3rd Edition
    • David T. Curiel + 1 more
    • English
    Adenoviral Vectors for Gene Therapy, Third Edition, provides detailed, comprehensive coverage of gene delivery vehicles based on the adenovirus that is emerging as an important tool in gene therapy. These exciting new therapeutic agents have great potential for the treatment of disease, as platforms for gene therapy and gene editing, as well as for oncology approaches, making them class leading agents in the gene-advanced therapies arena.The fully updated and expanded third edition covers the basic biology of adenoviruses and highlights the potential use of adenoviral vectors for the treatment of disease, including their construction, propagation, and purification, cutting-edge vectorology, and the use of adenoviral vectors in preclinical animal models. The book also considers the regulatory issues surrounding human clinical gene therapy trials. New chapters include adenoviral vaccines for veterinary applications, adenoviruses for gene editing, nonhuman primate adenoviruses, COVID-19 vaccines, vaccine applications, and oncolytic adenoviruses for antitumor immunization. This broad scope of information provides a solid overview of the field, allowing the reader to gain a complete understanding of the development and use of adenoviral vectors.

  • Innovative Conservation Techniques and Perspectives

    Global Biome Conservation and Global Warming Impacts on Ecology and Biodiversity
    • 1st Edition
    • Germano Leão Demolin-Leite
    • English
    Innovative Conservation Techniques and Perspectives: Global Biome Conservation and Global Warming Impacts on Ecology and Biodiversity explores operational and potential monitoring tools to conserve and/or recover biomes at a global scale. Written by international experts in ecology and biodiversity conservation, this book identifies operational, emerging, and proposed methods for land monitoring and management across the world’s biomes. This important resource on biodiversity is an ideal resource for students, professors, researchers, and both governmental and non-governmental organizations active in biodiversity conservation.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 126
    • English
    Advances in Clinical Chemistry, Volume 126, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians, and research scientists. Chapters in this new release include Internalization of Extracellular Tau Oligomers in Alzheimer’s Disease, Advances in Neurofilament Light Chain Analysis, Biomarkers of Endometriosis, Lupus Nephritis II: Treatment and Monitoring, and Emerging Biomarkers in Type 2 Diabetes Mellitus, Coagulopathy Prediction in Traumatic Brain Injury.

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