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Elsevier

Books in Life sciences

  • Lactose

    Evolutionary Role, Health Effects, and Applications
    • 1st Edition
    • Marcel Paques + 1 more
    • English
    Lactose: Evolutionary Role, Health Effects, and Applications is a professional reference that addresses the latest research from the fields of food science, nutritional science, and evolutionary biology. The book presents an overview of the qualities of lactose, beginning with the intriguing evolutionary biology advantages linked to lactose digestion in humans. In addition, the book addresses how lactose’s physiological effects differ from other saccharides and impact human health. The rationale for the application of lactose as an ingredient in products—for example, as a pharmaceutical carrier—is also discussed. Written in close collaboration by key experts with years of study and practice, Lactose: Evolutionary Role, Health Effects, and Applications is the first book to address this topic exclusively. Scientists and nutritionists in academia and the dairy and food industry, as well as health professionals, will benefit from this valuable resource.

  • Encyclopedia of Ocean Sciences

    • 3rd Edition
    • J. Kirk Cochran + 2 more
    • English
    The oceans cover 70% of the Earth’s surface, and are critical components of Earth’s climate system. This new edition of Encyclopedia of Ocean Sciences, Six Volume Set summarizes the breadth of knowledge about them, providing revised, up to date entries as well coverage of new topics in the field. New and expanded sections include microbial ecology, high latitude systems and the cryosphere, climate and climate change, hydrothermal and cold seep systems. The structure of the work provides a modern presentation of the field, reflecting the input and different perspective of chemical, physical and biological oceanography, the specialized area of expertise of each of the three Editors-in-Chief. In this framework maximum attention has been devoted to making this an organic and unified reference.

  • Amphibians of North Africa

    • 1st Edition
    • Daniel Escoriza + 1 more
    • English
    Amphibians of North Africa is a comprehensive compilation of available data on the amphibians and reptiles found in various ecosystems across North West Africa and parts of the Mediterranean region. It is essential to identifying and understanding the ecological role of regional herpetofauna and its conservational importance. It examines the biological origins and diversity of amphibians in North Africa, along with their diverse ecosystems, including deserts, grasslands and subtropical forests. The book features detailed descriptions of the adult and larvae stages of species, such as the North African fire salamander, the common painted frog, Brongersma's toad and the Mediterranean tree frog. This book is a vital resource for herpetology and ecology students and researchers, helping them identify, understand and conserve these amphibians and reptiles in their various habitats across the North African and Mediterranean regions.

  • Osseointegration of Orthopaedic Implants

    • 1st Edition
    • Amirhossein Goharian
    • English
    Osseointegration of Orthopaedic Implants helps product developers at orthopedic implant manufacturers enhance the effectiveness of orthopedic implants and reduce complications, particularly in patients with osteoporotic bones. The book's expert contributors provide cutting-edge information on the latest technologies and advances available. Biomaterial researchers can use the book for basic data in the further development of orthopedic implant materials with better osseointegration. Biomechanical researchers can review related challenges and concepts of osseointegration for use in the development of implants. The book is suitable for readers from academia and industry, bridging the knowledge gap between academic based researchers, industrial based engineers, and clinical based surgeons.

  • Curcumin for Neurological and Psychiatric Disorders

    Neurochemical and Pharmacological Properties
    • 1st Edition
    • Tahira Farooqui + 1 more
    • English
    Curcumin for Neurological and Psychiatric Disorders: Neurochemical and Pharmacological Properties focuses on the different molecular mechanisms underlying curcumin-mediated beneficial effects in neurological diseases. The book's editors discuss the neurochemical and pharmacological properties of curcumin, followed by the effect of curcumin in neurotraumatic diseases, neurodegenerative diseases, and neuropsychiatric diseases. The book also offers a perspective on future studies on the treatment of neurological disorders. The beneficial effects of curcumin have been observed both in cultured cells and in animal models, thus paving the way for ongoing present and future human clinical trials. Curcumin produces antioxidant and anti-inflammatory effects not only by blocking oxidative stress and neuroinflammation in neurotraumatic and neurodegenerative diseases, but also by restoring cellular homeostasis and rebalancing redox equilibrium.

  • Nano-Biopesticides Today and Future Perspectives

    • 1st Edition
    • Opender Koul
    • English
    Nano-Biopesticides Today and Future Perspectives is the first single-volume resource to examine the practical development, implementation and implications of combining the environmentally aware use of biopesticides with the potential power of nanotechnology. While biopesticides have been utilized for years, researchers have only recently begun exploring delivery methods that utilize nanotechnology to increase efficacy while limiting the negative impacts traditionally seen through the use of pest control means. Written by a panel of global experts, the book provides a foundation on nano-biopesticide development paths, plant health and nutrition, formulation and means of delivery. Researchers in academic and commercial settings will value this foundational reference of insights within the biopesticide realm.

  • Practical Guide for Biomedical Signals Analysis Using Machine Learning Techniques

    A MATLAB Based Approach
    • 1st Edition
    • Abdulhamit Subasi
    • English
    Practical Guide for Biomedical Signals Analysis Using Machine Learning Techniques: A MATLAB Based Approach presents how machine learning and biomedical signal processing methods can be used in biomedical signal analysis. Different machine learning applications in biomedical signal analysis, including those for electrocardiogram, electroencephalogram and electromyogram are described in a practical and comprehensive way, helping readers with limited knowledge. Sections cover biomedical signals and machine learning techniques, biomedical signals, such as electroencephalogram (EEG), electromyogram (EMG) and electrocardiogram (ECG), different signal-processing techniques, signal de-noising, feature extraction and dimension reduction techniques, such as PCA, ICA, KPCA, MSPCA, entropy measures, and other statistical measures, and more. This book is a valuable source for bioinformaticians, medical doctors and other members of the biomedical field who need a cogent resource on the most recent and promising machine learning techniques for biomedical signals analysis.

  • Central Serous Chorioretinopathy

    • 1st Edition
    • Jay Chhablani
    • English
    Central Serous Chorioretinopathy discusses the mechanisms, pathogenesis and risk factors of CSCR, findings on various imaging modalities, available treatment options, and translational research into new treatment options for CSCR management. This comprehensive book is written for retina specialists and surgeons, researchers and clinical practitioners in sensory systems (vision), and ophthalmologists. Central Serous Chorioretinopathy (CSCR) is a common disorder across the world with a variable prognosis without any standard of care. Recently, advancements in imaging have led to a better understanding of the pathogenesis and mechanisms of this disease.

  • Advances in Cancer Research

    • 1st Edition
    • Volume 142
    • English
    Advances in Cancer Research, Volume 142, the latest release in this ongoing, well-regarded serial, provides invaluable information on the exciting and fast-moving field of cancer research.

  • Pharmaceutical Care in Digital Revolution

    Insights Towards Circular Innovation
    • 1st Edition
    • Claudia Rijcken + 1 more
    • English
    Pharmaceutical Care in Digital Revolution demonstrates how blending human and digital pharmaceutical care can establish optimal Apothecary Intelligence (AI). Organized into four parts, it examines digital health advances that will synergize the pharmaceutical care process and prepares stakeholders for a dynamic future, fueled with innovation. Beginning with the global picture on health care systems, patients’ expectations, and current pharmaceutical care practices, the book covers details of relevant digital technologies as well as compliance, ethical, educational, and cultural aspects to take successful steps towards digital pharmaceutical care. The text includes links to lectures and technology facts, tutorials on how to implement advances in your own working environment, and examples of stakeholders who are successful in building synergy between digital and pharma. Pharmaceutical Care in Digital Revolution is a practical resource to equip pharmaceutical care stakeholders, such as pharmacists, physicians, pharmacy technicians, and students as well as those in surrounding ecosystems like payers or regulators. It is a crucial reference to understand how technological innovation is changing the paradigm in which we provide current and future pharmaceutical care and how to keep it accessible, affordable, and sustainable.

  • Plant Signaling Molecules

    Role and Regulation under Stressful Environments
    • 1st Edition
    • M. Iqbal R. Khan + 3 more
    • English
    Plant Signaling Molecule: Role and Regulation under Stressful Environments explores tolerance mechanisms mediated by signaling molecules in plants for achieving sustainability under changing environmental conditions. Including a wide range of potential molecules, from primary to secondary metabolites, the book presents the status and future prospects of the role and regulation of signaling molecules at physiological, biochemical, molecular and structural level under abiotic stress tolerance. This book is designed to enhance the mechanistic understanding of signaling molecules and will be an important resource for plant biologists in developing stress tolerant crops to achieve sustainability under changing environmental conditions.

  • Reproducibility in Biomedical Research

    Epistemological and Statistical Problems
    • 1st Edition
    • Erwin B. Montgomery Jr.
    • English
    Reproducibility in Biomedical Research: Epistemological and Statistical Problems explores the ideas and conundrums inherent in scientific research. It explores factors of reproducibility, including logic, distinguishing productive from unproductive irreproducibility, the scientific method, and the use of statistics. In multiple examples and six detailed case studies, the book demonstrates the misuse of logic resulting in unproductive irreproducibility, allowing researchers to develop their own logic and planning abilities. Biomedical researchers, clinicians, administrators of scientific institutions and funding agencies, journal editors, philosophers of science and medicine will find the arguments and explorations a valuable addition to their libraries.

  • EEG-Based Brain-Computer Interfaces

    Cognitive Analysis and Control Applications
    • 1st Edition
    • Dipali Bansal + 1 more
    • English
    EEG-Based Brain-Computer Interface: Cognitive Analysis and Control Applications provides a technical approach to using brain signals for control applications, along with the EEG-related advances in BCI. The research and techniques in this book discuss time and frequency domain analysis on deliberate eye-blinking data as the basis for EEG-triggering control applications. In addition, the book provides experimental scenarios and features algorithms for acquiring real-time EEG signals using commercially available units that interface with MATLAB software for acquisition and control.

  • Progress in Medicinal Chemistry

    • 1st Edition
    • Volume 58
    • English
    Progress in Medicinal Chemistry, Volume 58, provides a review of eclectic developments in medicinal chemistry, with each chapter written by an international board of authors. Topics covered in this new release include Amyotrophic lateral sclerosis (ALS), Covalent-binding Drugs, Natural Product Drug Delivery – A Special Challenge?, and SMN2 gene splicing modifier, and more.

  • Highlighting Operational and Implementation Research for Control of Helminthiasis

    • 1st Edition
    • Volume 103
    • English
    Highlighting Operational and Implementation Research for Control of Helminthiasis, Volume 103 in the Advances in Parasitology series, includes medical studies of parasites of major influence, along with reviews of more traditional areas, such as zoology, taxonomy and life history, all topics which help to shape current thinking and applications. This latest release includes chapters on Helminthiasis Epidemiology and Control: Scoring Successes and Meeting the Remaining Challenges, Worms, History and Swiss TPH, Mobile Microscopy, Combination Chemotherapy, DNDi Portfolio, Pediatric Praziquantel, lessons learned, and Community and Drug Distributor Perceptions and Experiences of Mass Drug Administration for the Elimination of Lymphatic Filariasis, amongst other topics.

  • Handbook of Sleep Disorders in Medical Conditions

    • 1st Edition
    • Josee Savard + 1 more
    • English
    Handbook of Sleep Disorders in Medical Conditions reviews the current knowledge on the nature and manifestations of sleep disorders associated with a variety of common medical conditions, including epilepsy, traumatic brain injury and dementia. It also provides clinical guidelines on how to assess and treat them with pharmacological and non-pharmacological interventions. Although the general principles of sleep medicine may be applied to some extent to patients with comorbid medical conditions, this book makes the case that an adaptive approach is warranted when considering the particularities of each condition. In addition, clinicians must also be cautious when prescribing sleep medications as some pharmacological agents are known to exacerbate symptoms associated with the medical condition, such as cognitive deficits (i.e. difficulties with memory and attention) in cancer patients experiencing chemo brain, or in persons with neurologic conditions (e.g. mild cognitive impairment, dementia, stroke, brain injury). A differential approach to evaluating and treating sleep is thus warranted.

  • Genes, Brain Function, and Behavior

    What Genes Do, How They Malfunction, and Ways to Repair Damage
    • 1st Edition
    • Douglas Wahlsten
    • English
    Genes, Brain Function, and Behavior offers a concise description of the nervous system that processes sensory input and initiates motor movements. It reviews how behaviors are defined and measured, and how experts decide when a behavior is perturbed and in need of treatment. Behavioral disorders that are clearly related to a defect in a specific gene are reviewed, and the challenges of understanding complex traits such as intelligence, autism and schizophrenia that involve numerous genes and environmental factors are explored. New methods of altering genes offer hope for treating or even preventing difficulties that arise in our genes. This book explains what genes are, what they do in the nervous system, and how this impacts both brain function and behavior.

  • Ecometabolomics

    Metabolic Fluxes versus Environmental Stoichiometry
    • 1st Edition
    • Sumira Jan + 1 more
    • English
    Ecometabolomics: Metabolic Fluxes versus Environmental Stoichiometry focuses on the interaction between plants—particularly plants that have vigorous secondary metabolites—and the environment. The book offers a comprehensive overview of the responses of the metabolome of organisms to biotic and abiotic environmental changes. It includes an introduction to metabolomics, summaries of metabolomic techniques and applications, studies of stress in plants, and insights into challenges. This is a must-have reference for plant biologists, plant biochemists, plant ecologists and phytochemists researching the interface between plants and the environment using metabolomics.

  • Platelets

    • 4th Edition
    • Alan D. Michelson + 3 more
    • English
    Platelets, Fourth Edition, integrates the entire field of platelet biology, pathophysiology, and clinical medicine with contributions from 142 world experts from 18 countries. This award-winning reference provides clear presentations by basic scientists on the cellular, molecular, and genetic mechanisms of platelets and the role of platelets in thrombosis, hemorrhage, inflammation, antimicrobial host defense, wound healing, angiogenesis and cancer. It also provides start-of-the-art presentations by hematologists, cardiologists, stroke physicians, blood bankers, pathologists and other clinicians on platelet function testing, disorders of platelet numbers and function, antiplatelet therapy and therapy to increase platelet numbers and/or function. Since the publication of the Third Edition of Platelets, there has been a rapid expansion of knowledge in both basic biology of platelets and the clinical approach to platelet-related diseases. This Fourth Edition of Platelets draws all this information into a single, comprehensive and authoritative resource.

  • Anorectal Disorders

    Diagnosis and Non-Surgical Treatments
    • 1st Edition
    • Enrique Coss-Adame + 1 more
    • English
    Anorectal Disorders: Diagnosis and Nonsurgical Treatments incorporates the most recent major advances in the understanding of anal and rectal anatomy to provide clinical evidence of care for those suffering from anorectal disorders. By condensing basic and practical aspects in the knowledge of anorectal disorders, this book provides a comprehensive review of the anatomy and physiology of the anorectal region. It includes new technology that expands and modifies current perceptions about the functional anatomy of the anorectal region and ultimately impacts how we conceive muscle and nerve structures functioning together to maintain fecal continence and properly execute the process of defecation. Perfect for medical researchers, gastroenterologists, general practitioners, internal medicine doctors and general surgeons, this title will provide diagnosis and treatment options for all patients suffering from anorectal disorders.

  • Ubiquitin and Ubiquitin-like Protein Modifiers

    • 1st Edition
    • Volume 618
    • English
    Ubiquitination and Protein Stability - Part A Volume 618, the latest release in the Methods in Enzymology series, highlights new advances in the field, with this updated volume presenting interesting chapter written by an international board of authors. Topics of note in this new release include the Preparation of ubiquitinated nucleosomes with native and non-hydrolyzable linkages, Methods to measure ubiquitin chain length and linkage, Genetic approaches to study the yeast ubiquitin system, Enzymatic preparation of monoubiquitinated proteins, Methods to distinguish the function of ubiquitin in autophagy and the proteasome pathway, the Purification and characterization of enzyme activity of USPs, and much more.

  • Non-alcoholic Beverages

    Volume 6. The Science of Beverages
    • 1st Edition
    • Alexandru Grumezescu + 1 more
    • English
    Nonalcoholic Beverages, Volume Six in The Science of Beverages series, offers a wide-range of knowledge and expertise from research professionals around the world. The book focuses on the research and development of innovative products and new growing trends based on consumer demand for natural drinks that have health benefits. The book discusses the properties and benefits of developing nonalcoholic beverages, their production particularities, associated properties, physiochemical characteristics, and methods to help researchers and students learn about utilized nonalcoholic beverages.

  • Fermented Beverages

    Volume 5. The Science of Beverages
    • 1st Edition
    • Alexandru Grumezescu + 1 more
    • English
    Fermented Beverages, Volume Five, the latest release in The Science of Beverages series, examines emerging trends and applications of different fermented beverages, including alcoholic and non-alcoholic drinks. The book discusses processing techniques and microbiological methods for each classification, their potential health benefits, and overall functional properties. The book provides an excellent resource to broaden the reader’s understanding of different fermented beverages. It is ideal for research and development professionals who are working in the area of new products.

  • Molecular Biology Techniques

    A Classroom Laboratory Manual
    • 4th Edition
    • Sue Carson + 3 more
    • English
    Molecular Biology Techniques: A Classroom Laboratory Manual, Fourth Edition is a must-have collection of methods and procedures on how to create a single, continuous, comprehensive project that teaches students basic molecular techniques. It is an indispensable tool for introducing advanced undergraduates and beginning graduate students to the techniques of recombinant DNA technology—or gene cloning and expression. The techniques used in basic research and biotechnology laboratories are covered in detail. Students will gain hands-on experience on subcloning a gene into an expression vector straight through to the purification of the recombinant protein.

  • Pharmacoepidemiology and Pharmacovigilance

    • 1st Edition
    • Pascale Tubert-Bitter + 2 more
    • English
    Pharmacoepidemiology and Pharmacovigilance provides understanding of up-to-date statistical methods applied to drug safety assessment from observational data. Postmarketing drug safety raises challenging methodological issues.

  • Neural Stem Cells and Adult Neurogenesis

    • 1st Edition
    • Arie S. Mobley
    • English
    Neural Stem Cells and Adult Neurogenesis provides graduate students and neuroscientists with a basic understanding of what neural stem cells are and the cell types they produce. This early graduate level reference describes their physiology and potential for medicine and provides students with fundamental stem cell information. An overview of stem cell sources in the human body and a brief mention of relevant diseases provide context for the value of this knowledge. The book also includes chapters on induced pluripotent stem cells (iPSCs), the methods used to obtain them, and a review of the ethical challenges associated with stem cell research. For each region, the book provides a description of its neurogenic niche, cellular and molecular biology, and information on the neurons’ contribution to normal and diseased brain function. The level of information is appropriate for early graduate students, introducing technology and molecular biology in an accessible format.

  • Comprehensive Overview of Modern Surgical Approaches to Intrinsic Brain Tumors

    • 1st Edition
    • Kaisorn Chaichana + 1 more
    • English
    Comprehensive Overview of Modern Surgical Approaches to Intrinsic Brain Tumors addresses limitations in the scientific literature by focusing primarily on surgical approaches to various intrinsic neoplasms using diagrams and step-by-step instructions. It provides the advantages and disadvantages of these approaches, controversies, and technical considerations and discusses topics such as anatomy, pathology and animal models, imaging, open brain tumor approaches and minimally invasive approaches. Additionally, it discusses controversial treatments and the pros and cons of each. This book is a valuable source for medical students, neurosurgeons and any healthcare provider who has an interest in brain tumors and techniques to treat them.

  • Flour and Breads and Their Fortification in Health and Disease Prevention

    • 2nd Edition
    • Victor R. Preedy + 1 more
    • English
    Flour and Breads and Their Fortification in Health and Disease Prevention, Second Edition, presents the healthful benefits of flours and flour products and guides the reader on how to identify opportunities for improving health through the use of flour and fortified flour products. The book examines flour and bread related agents that affect metabolism and other health-related conditions, explores the impact of compositional differences between flours, including differences based on country of origin and processing technique, and includes methods for the analysis of flours and bread-related compounds in other foods. This revised, updated edition contains new research on diverse flours with an emphasis on nutrients and nutraceuticals as supplements, thus making this content a timely reference for both nutritionists and food scientists.

  • Nucleic Acid Nanotheranostics

    Biomedical Applications
    • 1st Edition
    • Marco Filice + 1 more
    • English
    Nucleic Acid Nanotheranostics: Biomedical Applications offers a comprehensive overview of improvements and new trends in fabrication of nanostructures as theranostic multifunctional carriers in gene therapy. With a strong focus on medical applications (comprising diagnosis, therapy and imaging), the book also examines gene therapy in an individual patient’s cells or tissues to treat genetic diseases. Sections cover Biomedical and Diagnostic applications of Nucleic Acids, Biologic and Synthetic Advanced Nanostructures for nucleic acid delivery, and important considerations of nanomedicine. This book is a valuable guide for materials scientists, physicians, chemists and engineers, but is also ideal for clinicians wishing to expand their knowledge.

  • Breaking Tolerance to Pancreatic Cancer Unresponsiveness to Chemotherapy

    • 1st Edition
    • Volume 5
    • English
    Breaking Tolerance to Pancreatic Cancer Unresponsiveness to Chemotherapy edited by Dr. Nagaraju, PhD., DSc. focuses on overriding the resistance from chemotherapeutic drugs with a broader range of treatment options. It particularly focuses on stroma, tumor microenvironment, stem cells, stellate cells, transcription factors, growth factors, and important signaling pathways. This volume discusses topics such as pancreatic cancer biology, current therapeutic options, EMT, chemotherapy resistance mechanisms, and genetic manipulations and natural products to enhance the sensitivity of pancreatic cancer to chemotherapy. Additionally, it discusses small targeted molecules and pancreatic cancer trials, and nanotechnology-based drug delivery.Breaking Tolerance to Pancreatic Cancer Unresponsiveness to Chemotherapy is a valuable source for researchers and advanced students in cancer and oncology as well as clinicians and medical students who are interested in learning more about ways to break pancreatic cancer resistance to chemotherapy.

  • Genetic Breeding and Molecular Marker-Assisted Selective Breeding of Largemouth Bass

    • 1st Edition
    • Bai Junjie + 1 more
    • English
    Genetic Breeding and Molecular Marker-Assisted Selective Breeding of Largemouth Bass provides evidenced-based research that summarizes the theory and practice of genetic breeding. It provides a theoretical basis and technical support for the genetic improvement of largemouth bass varieties, but is also a good reference on the genetic breeding of other farmed fish. As knowledge of systematic studies, including germplasm resources, biology, quantitative genetics, selection breeding, variety hybridization and molecular marker assisted breeding is needed to increase growth performance, this book provides comprehensive information that is suitable for aquatic genetic breeding researchers and undergraduate and graduate students in aquatic genetics and breeding.

  • Iron Metabolism: Hepcidin

    • 1st Edition
    • Volume 110
    • Gerald Litwack
    • English
    Iron Metabolism, Volume 110, the latest release in the Vitamins and Hormones series first published in 1943, covers the field of hormone action, vitamin action, X-ray crystal structure, physiology and enzyme mechanisms, with this release focusing on topics relating to hepcidin, bacterial infection, and iron overload, the role of heparan sulfates in hepcidin regulation, hepcidin CDNA and human gene sex hormones, growth factors and hepcidin, HFE gene polymorphisms and hereditary hemochromatosis, hepcidin and il-1beta, hepcidin-ferroportin axis, cardiomyocyte hepcidin, adipocyte iron, leptin and hepcidin, regulators of hepcidin expression, and much more.

  • Advances in Applied Microbiology

    • 1st Edition
    • Volume 106
    • Geoffrey M. Gadd + 1 more
    • English
    Advances in Applied Microbiology, Volume 106, continues the comprehensive reach of this widely read and authoritative review source in microbiology. Users will find invaluable references and information on a variety of areas, with this updated volume including chapters covering The role and regulation of the stress activated sigma factor SigB in the saprophytic and host-associated life stages of the pathogen Listeria monocytogenes, Bacterial synthesis of Se nanoparticles, Siderophores in environmental research, Methods to reduce spoilage and microbial contamination of plant produce, Nitrogen cycling during wastewater treatment, Oxalic acid, a molecule at crossroads of bacterial-fungal interactions, and Bacterial spores, from ecology to biotechnology.

  • Nucleic Acid Sensing and Immunity, Part A

    • 1st Edition
    • Volume 344
    • English
    Nucleic Acid Sensing and Immunity - PART A, Volume 344, provides a comprehensive overview of the nucleic acid machinery, from plants to mammalians, as well as their regulation. Specific chapters in this updated release include Molecular bases of discrimination between self from non-self nucleic acids, Intracellular RNA sensing in mammalian cells, Nuclear DNA damage and nucleic acid sensing, Negative regulation of nucleic acid sensing, Dendritic cell responses to exogenous nucleic acids, Activating the nucleic acid-sensing machinery for anticancer immunity, and Nucleic acid sensing and inflammasomes, amongst other topics.

  • Malignant Pleural Mesothelioma

    A Guide for Clinicians
    • 1st Edition
    • Antonio Giordano + 1 more
    • English
    Malignant Pleural Mesothelioma: A Guide for Clinicians is a practical book developed to assist clinicians, pathologist and molecular biologist in the management of malignant pleural mesothelioma (MPM). MPM represents a challenge in terms of diagnosis, staging and treatment, and to date, the optimal management of MPM patients has not yet been clearly defined – and this book is intended to be an efficient tool for these cases. The book encompasses topics such as epidemiology and surveillance evidence, multimodality imaging assessment of MPM, pathology, molecular mechanisms and treatment of such disease. Additionally, it discusses the standard operative procedures and the future directions for the management of MPM from experts’ experiences. Malignant Pleural Mesothelioma: A Guide for Clinicians is a valuable source for oncologists, pathologist, cancer researchers, thoracic specialists and several members of biomedical field who needs to learn more from experts about the diagnosis, operative procedures and treatment of malignant pleural mesothelioma.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 89
    • Gregory S. Makowski
    • English
    Advances in Clinical Chemistry, Volume 89, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry, and is the benchmark for novel analytical approaches in the clinical laboratory.

  • Organ Development

    • 1st Edition
    • Volume 132
    • English
    Organ Development, Volume 132, the latest release in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapter written by an international board of authors. This volume highlights cogent reviews of the development, maintenance and regeneration/repair of several organ systems, from eye to kidney, to the musculoskeletal system. Many reviews highlight new techniques or technologies that are currently pushing the field. The role of both embryonic and adult stem cells are highlighted and senior authors are all women scientists.

  • Basic and Applied Bone Biology

    • 2nd Edition
    • David B. Burr + 1 more
    • English
    Basic and Applied Bone Biology, Second Edition, provides an overview of skeletal biology, from the molecular level, to the organ level, including cellular control, interaction and response, adaptive responses to various external stimuli, and the interaction of the skeletal system with other metabolic processes in the body. The book includes chapters that address how the skeleton can be evaluated through the use of various imaging technologies, biomechanical testing, histomorphometric analysis, and the use of genetically-modified animal models. Each chapter delves deep into the important details of topics covered to provide a solid understanding of the basics of bone biology. Bone biology researchers who also train undergraduate and graduate students in the lab will use this book constantly to orient new students on the basics of the field and as a background reference for many of the technical aspects of qualification in bone biology (e.g., mechanics, histomorphometry, genetic modification, biochemistry, etc.).

  • DNA Repair

    • 1st Edition
    • Volume 115
    • English
    DNA Repair, Volume 115, the latest release in the Advances in Protein Chemistry and Structural Biology series, provides an overview of current developments in mechanisms underlying DNA repair, their involvement in maintaining chromatin repair, the balance between chromosome breaks repair pathways, tumorigenesis, immune signaling and infection-induced inflammation. Specific chapters cover the Structure and function of the multi-subunit TFIIH with insights into nucleotide excision repair, Chromatin repair: how DNA packaging controls double-strand break repair, Controlling the balance between chromosome breaks repair pathways, The targeting of DNA repair pathways in the era of precision oncology, and much more.

  • Metabolons and Supramolecular Enzyme Assemblies

    • 1st Edition
    • Volume 617
    • English
    Metabolons and Supramolecular Enzyme Assemblies, Volume 617 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Dynamic plant metabolons, TCA cycle metabolons, the Chemotactic assembly of metabolons, Repurposing peroxisomes for metabolic engineering, Repurposing yeast mitochondria for metabolic engineering, Repurposing plant compartments for metabolic engineering, Protein scaffolds for pathway co-localization on lipid droplets, Engineered enzyme assemblies for metabolic engineering, NRPS assembly lines and P450 interactions, and much more.

  • Bioarchaeology of Marginalized People

    • 1st Edition
    • Madeleine L. Mant + 1 more
    • English
    Bioarchaeology of Marginalized People amplifies the voices of marginalized or powerless individuals. Following previous work done by physical anthropologists on the biology of poverty, this volume focuses on the voices of past actors who would normally be subsumed within a cohort or whose stories represent those of the minority. The physical effects of marginalization – manifest as skeletal markers of stress and disease – are read in their historical contexts to better understand vulnerability and the social determinants of health in the past. Bioarchaeological, archaeological, and historical datasets are integrated to explore the varied ways in which individuals may be marginalized both during and after their lifespan. By focusing on previously excluded voices this volume enriches our understanding of the lived experience of individuals in the past. This volume queries the diverse meanings of marginalization, from physical or social peripheralization, to identity loss within a majority population, to a collective forgetting that excludes specific groups. Contributors to the volume highlight the histories of individuals who did not record their own stories, including two disparate Ancient Egyptian women and individuals from a high-status Indigenous cemetery in British Columbia. Additional chapters examine the marginalized individuals whose bodies comprise the Robert J. Terry anatomical collection and investigate inequalities in health status in individuals from Canada, the United States, and the United Kingdom. Modern clinical population health research is examined through a historical lens, bringing a new perspective to the critical public health interventions occurring today. Together, these papers highlight the role that biological anthropologists play both in contributing to and challenging the marginalization of past populations.

  • Gap Junction Structure and Chemical Regulation

    Direct Calmodulin Role in Cell-to-Cell Channel Gating
    • 1st Edition
    • Camillo Peracchia
    • English
    Gap Junction Structure and Chemical Regulation: Direct Calmodulin Role in Cell-to-Cell Channel Gating describes and discusses the findings of major studies conducted during the past century on the structure and chemical regulation of direct cell-to-cell communication via gap junction channels. Chapters bring together important findings on direct cell communication, from its history, to its structure and regulation. These channels are essential for normal organ function, and mutations in their protein (connexin) cause various diseases. The book is useful for established investigators who need a review on the field and young investigators who need a thorough resource for study and comprehension.

  • Echinoderms

    • 1st Edition
    • Volume 150
    • English
    Echinoderms, Volume 150 in the Methods in Cell Biology series, highlights new advances in the field, with this update presenting interesting chapters on procuring animals and culturing of eggs and embryos, cryopreservation of sea urchin gametes, emerging echinoderm models, culturing of sand dollars, cidaroids and heart urchins, culturing echinoderm larvae through metamorphosis, microinjection methods, injection of exogenous messages and protein overexpression, blastomere transplantation, visualization of embryonic polarity, larval immune cell approaches, methods for analysis of sea urchin primordial germ cells, and protocols and best practices for toxicology and pH studies using echinoderms and　several new chapters outlining the use of sea urchins in the classroom.

  • Bottled and Packaged Water

    Volume 4: The Science of Beverages
    • 1st Edition
    • Alexandru Grumezescu + 1 more
    • English
    Bottled and Packaged Water, Volume Four in The Science of Beverages series, offers great perspectives on current trends in drinking water research, quality control techniques, packaging strategies, and current concerns in the field, thus revealing the most novel standards in the industry. As consumer demand for bottled and packaged water has increased, the need for scientists and researchers to understand how to analyze water quality, safety, and control are essential. This all-encompassing resource for research and development in this flourishing field covers everything from sensory and chemical composition, to materials and manufacturing.

  • Modeling and Control of Infectious Diseases in the Host

    With MATLAB and R
    • 1st Edition
    • Esteban A. Hernandez-Vargas
    • English
    Modeling and Control of Infectious Diseases in the Host: With MATLAB and R provides a holistic understanding of health and disease by presenting topics on quantitative decision-making that influence the development of drugs. The book presents modeling advances in different viral infections, dissecting detailed contributions of key players, along with their respective interactions. By combining tailored in vivo experiments and mathematical modeling approaches, the book clarifies the relative contributions of different underlying mechanisms within hosts of the most lethal viral infections, including HIV, influenza and Ebola. Illustrative examples for parameter fitting, modeling and control applications are explained using MATLAB and R.

  • Biomarkers in Toxicology

    • 2nd Edition
    • Ramesh C. Gupta
    • English
    Biomarkers in Toxicology, Second Edition, is a timely and comprehensive reference dedicated to all aspects of biomarkers that relate to chemical exposure and their effects on biological systems. This revised and completely updated edition includes both vertebrate and non-vertebrate species models for toxicological testing and the development of biomarkers. Divided into several key sections, this reference volume contains new chapters devoted to topics in microplastics, neuroimmunotoxicity and nutraceuticals, along with a look at the latest cutting-edge technologies used to detect biomarkers. Each chapter contains several references to current literature and important resources for further reading. Given this comprehensive treatment, this book is an essential reference for anyone interested in biomarkers across the scientific and biomedical fields.

  • In Silico Drug Design

    Repurposing Techniques and Methodologies
    • 1st Edition
    • Kunal Roy
    • English
    In Silico Drug Design: Repurposing Techniques and Methodologies explores the application of computational tools that can be utilized for this approach. The book covers theoretical background and methodologies of chem-bioinformatic techniques and network modeling and discusses the various applied strategies to systematically retrieve, integrate and analyze datasets from diverse sources. Other topics include in silico drug design methods, computational workflows for drug repurposing, and network-based in silico screening for drug efficacy. With contributions from experts in the field and the inclusion of practical case studies, this book gives scientists, researchers and R&D professionals in the pharmaceutical industry valuable insights into drug design.

  • EEG Brain Signal Classification for Epileptic Seizure Disorder Detection

    • 1st Edition
    • Sandeep Kumar Satapathy + 3 more
    • English
    EEG Brain Signal Classification for Epileptic Seizure Disorder Detection provides the knowledge necessary to classify EEG brain signals to detect epileptic seizures using machine learning techniques. Chapters present an overview of machine learning techniques and the tools available, discuss previous studies, present empirical studies on the performance of the NN and SVM classifiers, discuss RBF neural networks trained with an improved PSO algorithm for epilepsy identification, and cover ABC algorithm optimized RBFNN for classification of EEG signal. Final chapter present future developments in the field. This book is a valuable source for bioinformaticians, medical doctors and other members of the biomedical field who need the most recent and promising automated techniques for EEG classification.

  • Therapeutic Application of Nitric Oxide in Cancer and Inflammatory Disorders

    • 1st Edition
    • Lucia Morbidelli + 1 more
    • English
    Therapeutic Application of Nitric Oxide in Cancer and Inflammatory Disorders presents updated reviews on the chemistry, signaling, pre-clinical and clinical activities on the role of nitric oxide donors/inhibitors used alone and in combination with other therapeutic agents for the treatment of a variety of diseases. This book examines various studies related to the application of novel therapeutic NO (donors/inhibitors) compounds in the treatment of various cancers. These studies have been shown to exert significant therapeutic activities against various cancers and various inflammatory diseases such as rheumatoid arthritis, Crohn’s disease, allergies, and asthma, where no current effective therapies exist. Pathologies based on functional and structural vascular alterations are also taken into consideration. Edited and written by internationally renowned experts in the field of novel therapeutics for cancer, this book is a valuable source for cancer researchers, medical scientists, clinicians, clinical pharmacologists, and graduate students.

  • Key Productivity and Performance Strategies to Advance Your Career

    • 1st Edition
    • Lesia L. Crumpton-Young
    • English
    Key Productivity and Performance Strategies to Advance Your STEM Career shares valuable knowledge and insights on best practices used by high performing individuals in the STEM fields to enhance their professional endeavors. The strategies contained in this book are based on Lesia L. Crumpton-Young's experience and expertise as a STEM professional and a certified Life and Career Coach. The book includes real-life examples from STEM professionals of career hurdles and efficient solutions to reaching your career goals. It covers effective goal setting, decision-making, and how best to overcome doubt and criticism, as well as practical advice on critical path analysis. Finally, the book includes a five-year career planning tool, along with additional problem statements and exercises, making it a valuable resource those involved in the STEM fields.

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