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Elsevier

Books in Life sciences

  • NETosis

    Immunity, Pathogenesis and Therapeutics
    • 1st Edition
    • Geeta Rai
    • English
    NETosis: Immunity, Pathogenesis and Therapeutics takes a focused approach to the clinical aspects of NETosis and drug development, bringing critical findings. Chapters introduce NETosis, consider mechanisms and antimicrobial strategies regulating NETosis, examine NETosis in neonates, explore the role of NETosis in autoimmunity, delve into NETosis and other diseases, and present therapeutic approaches for dysregulated NETosis. Since Brinkamm, et al, discovered an unrecognized neutrophil anti-microbial mechanism responsible for the extracellular killing of invading pathogens in 2004, the novel process in which nuclear chromatin de-condenses and DNA is ejected into the extra cellular environment, trapping and inactivating tissue pathogens has rapidly evolved.

  • The Mechanics of Inhaled Pharmaceutical Aerosols

    An Introduction
    • 2nd Edition
    • Warren H. Finlay
    • English
    The Mechanics of Inhaled Pharmaceutical Aerosols: An Introduction, Second Edition provides a concise, but thorough exposition of fundamental concepts in the field of pharmaceutical aerosols. This revised edition will allow researchers in the field to gain a thorough understanding of the field from first principles, allowing them to understand, design, develop and improve inhaled pharmaceutical aerosol devices and therapies. Chapters consider mechanics and deposition, specifically in the respiratory tract, while others discuss the mechanics associated with the three existing types of pharmaceutical inhalation devices. This text will be very useful for academics and for courses taught at both undergraduate and graduate levels. Because of the interdisciplinary nature of this book, it will also serve a wide audience that includes engineers and scientists involved with inhaled aerosol therapies.

  • Nutraceutical and Functional Food Regulations in the United States and around the World

    • 3rd Edition
    • Debasis Bagchi
    • English
    Nutraceutical and Functional Food Regulations in the United States and Around the World, Third Edition addresses the latest regulatory requirements designed to ensure the safe production and delivery of these valuable classes of foods. The book is well recognized, showing how food and nutrition play a critical role in enhancing human performance, and in overall health. The book discusses the scope, importance and continuing growth opportunities in the nutraceutical and functional food industries, exploring the acceptance and demand for these products, regulatory hurdles, the intricate aspects of manufacturing procedures, quality control, global regulatory norms and guidelines.

  • Pathophysiology of Ischemia Reperfusion Injury and Use of Fingolimod in Cardioprotection

    • 1st Edition
    • Naseer Ahmed
    • English
    Pathophysiology of Ischemia-Reperfusion Injury and Use of Fingolimod in Cardioprotection is a deep examination into the mechanisms of myocardial ischemiareperfusion injury and role of fingolimod as a cardioprotective agent through its antioxidant, anti-apoptotic and anti-inflammatory effects. Dr. Ahmed explore the physiology and pathophysiology of myocardial metabolism under normal and ischemic conditions and focused on pharmacological cardioprotection. They provide a concise, yet rigorous discussion of Ischemia-Reperfusion Injury, Myocardial Ischemia during Circulatory Arrest, Myocardial Reperfusion, Myocardial Protection related to Ischemia-Reperfusion Injury and Role of Fingolimod in Cardioprotection.Pat... of Ischemia-Reperfusion Injury and Use of Fingolimod in Cardioprotection is ideal for researchers, cardiovascular scientists, and clinical pharmacologists to further work in this challenging area and apply this knowledge to clinical trials for cardioprotection.

  • Metabolism, Structure and Function of Plant Tetrapyrroles: Introduction, Microbial and Eukaryotic Chlorophyll Synthesis and Catabolism

    • 1st Edition
    • Volume 90
    • English
    Metabolism, Structure and Function of Plant Tetrapyrroles, Volume 90, the latest release in the Advances in Botanical Research series is a compilation of the current state-of-the-art on the topic. Chapters in this new release cover Tetrapyrrole Pigments of Photosynthetic Antennae and Reaction Centers of Higher Plants: Biochemistry, Biophysics, Functions, Molecular Mechanism of Antenna Regulation, Applications, Chlorophyll c: Synthesis, Occurrence, Light-Harvesting, Absorbance, Excitation Properties, Pigment Organization in Chlorophyll-Binding Proteins (FCP), Chlorophyll d and f: Synthesis, Occurrence, Light-harvesting, Absorbance, Excitation Properties, Pigment Organization in Chlorophyll-Binding Protein Complexes, Analysis of Chlorophyll, Precursors and Derivatives by New High-Performance Liquid Chromatography and Mass Spectrometry, and much more.

  • The Immortal Germline

    • 1st Edition
    • Volume 135
    • English
    The Immortal Germline, Volume 135 in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Balbiani body, germ plasm and polarity, Wolbachia and the germline, Human germ line biology, Reproduction/immunit... and sperm success, Mammalian spermatogenesis, Reproduction/regener... and germ cells in planarians, Germline stem cell homeostasis, Germline soma interactions/sex determination, Reconstituting the mouse germ-cell specification pathway in vitro, Maternal Germ line inheritance of mitochondria, Transposon strategies, and more.

  • Chemical and Synthetic Biology Approaches to Understand Cellular Functions - Part B

    • 1st Edition
    • Volume 622
    • English
    Chemical and Synthetic Biology Approaches To Understand Cellular Functions - Part B, Volume 622, the latest release in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting chapters that cover the Design of optogenetic proteins, the Application of optogenetic proteins, Antibody aggregation mechanism probed by a fluorescently-labele... antibody with fluorescence correlation spectroscopy, Bimane labeling of B-arrestins to measure their interaction with GPCRs, Reversible biotinylation of proteins for investigating their interaction with partners, Chemical biology approaches to study RNA cytidine acetylation, Salt sensitive intein in robotic production of peptides, and much more.

  • Biomaterials and Bionanotechnology

    • 1st Edition
    • English
    Biomaterials and Bionanotechnology examines the current state of the field within pharmaceutical sciences and concisely explains the history of biomaterials including key developments. Written by experts in the field, this volume within the Advances in Pharmaceutical Product Development and Research series deepens understanding of biomaterials and bionanotechnology within drug discovery and drug development. Each chapter delves into a particular aspect of this fast-moving field to cover the fundamental principles, advanced methodologies and technologies employed by pharmaceutical scientists, researchers and pharmaceutical industries to transform a drug candidate or new chemical entity into a final administrable dosage form, with particular focus on biomaterials and bionanomaterials. This book provides a comprehensive examination suitable for researchers working in the pharmaceutical, cosmetics, biotechnology, food and related industries as well as advanced students in these fields.

  • Model Ecosystems in Extreme Environments

    • 1st Edition
    • Volume 2
    • English
    Model Ecosystems in Extreme Environments, Second Edition examines ecosystems at the most extreme habitats and their interaction with the environment, providing a key element in our understanding of the role and function of microorganisms in nature. The book highlights current topics in the field, such as biodiversity and the structure of microbial communities in extreme environments, the effects of extreme environmental conditions on microbial ecosystems, and ecological and evolutionary interactions in extreme environments, among other topics. It will be a valuable text for faculty and students working with extremophiles and/or microbial ecology and researchers, including astrobiologists, biologists, evolutionary scientists, astronomers, geochemists and oceanographers.

  • Food Applications of Nanotechnology

    • 1st Edition
    • Volume 88
    • English
    Food Applications of Nanotechnology, Volume 88, consolidates the literature on recent developments in nanotechnology, addressing production, safety and nutritional aspects pertaining to foods and nutraceuticals. Chapters in this new release include Assembled protein nanoparticles in food and nutrition applications, Nano-scale carbohydrate Materials in food/nutrition/agric... applications, Nanotechnology-based colloidal delivery systems in foods, Electrospinning and Electrospraying in food, Bioavailability of nanotechnology-based bioactives and nutraceuticals, and more.

  • Self-assessment Questions for Clinical Molecular Genetics

    • 1st Edition
    • Haiying Meng
    • English
    Review Questions of Clinical Molecular Genetics presents a comprehensive study guide for the board and certificate exams presented by the American College of Medical Genetics and Genomics (ACMG) and the American Board of Medical Genetics and Genomics (ABMGG). It provides residents and fellows in genetics and genomics with over 1,000 concise questions, ranging from topics in cystic fibrosis, to genetic counseling, to trinucleotide repeat expansion disorders. It puts key points in the form of questions, thus challenging the reader to retain knowledge. As board and certificate exams require knowledge of new technologies and applications, this book helps users meet that challenge.

  • Biochemistry of Collagens, Laminins and Elastin

    Structure, Function and Biomarkers
    • 2nd Edition
    • Morten Karsdal
    • English
    There are 28 different collagens, with 46 unique chains, which allows for a collagen for each time and place. Some collagens are specialized for basement membrane, whereas others are the central structural component of the interstitial matrix. There are eight collagens among the 20 most abundant proteins in the body, which makes these molecules essential building blocks of tissues. In addition, lessons learned from monogenomic mutations in these proteins result in grave pathologies, exemplifying their importance in development. These molecules, and their post-translationally modified products serve as biomarkers of diseases in a range of pathologies associated with the extracellular matrix. Biochemistry of Collagens, Laminins, and Elastin: Structure, Function, and Biomarkers, Second Edition provides researchers and students current data on key structural proteins (collagens, laminins, and elastin), reviews on how these molecules affect pathologies, and information on how selected modifications of proteins can result in altered signaling properties of the original extracellular matrix component. Further, it discusses the novel concept that an increasing number of components of the extracellular matrix harbor cryptic signaling functions that may be viewed as endocrine function, and it highlights how this knowledge can be exploited to modulate fibrotic disease.

  • Neuroscience of the Nonconscious Mind

    • 1st Edition
    • Rajendra Badgaiyan
    • English
    Neuroscience of the Nonconscious Mind includes novel concepts and insights on the brain mechanisms that control nonconscious mental functions, some of which were developed in the author’s laboratory. The book describes neuroscience of conventional nonconscious mental functions, along with not so conventional functions like creativity, hypnosis and extrasensory perception, thus making it a very unique reference. This thought provoking book for students of mind, brain and consciousness will help explain concepts and introduce the science behind the nonconscious.

  • The Little Black Book of Neurology

    • 6th Edition
    • Osama O. Zaidat + 2 more
    • English
    Widely known and well-respected, The Little Black Book of Neurology has been a thorough yet portable reference in this complex field for more than 30 years, presenting definitions, classifications, and guidance on diagnosis and management for a wide range of neurological disorders. The 6th Edition offers updated and expanded coverage of neuropharmacology and neuroimaging – plus a new, more user-friendly, fast-access format that makes the book ideal for quick clinical consultation or as a refresher for the Boards.

  • Human Brainstem

    Cytoarchitecture, Chemoarchitecture, Myeloarchitecture
    • 1st Edition
    • George Paxinos + 2 more
    • English
    Human Brainstem: Cytoarchitecture, Chemoarchitecture, Myeloarchitecture explores how the human brainstem has been impeded by the unavailability of an up-to-date, comprehensive, diagrammatic and photographic atlas. Now, with the first detailed atlas on the human brainstem in more than twenty years, this book presents an accurate, comprehensive and convenient reference for students, researchers and pathologists.

  • Pregnancy and the Pharmaceutical Industry

    The Movement towards Evidence-Based Pharmacotherapy for Pregnant Women
    • 1st Edition
    • Kristine E. Shields
    • English
    Pregnancy and the Pharmaceutical Industry: The Movement towards Evidence-Based Care for Pregnant Women explores the issues surrounding the decision to undertake clinical trials with pregnant women. There is currently a lack of data on the safety and effectiveness of medications used during pregnancy as it is impossible to extrapolate that information from drug studies on men and non-pregnant women. As a majority of pregnant women confront a medical condition during their pregnancy, from simple pain, to ongoing or new medical issues, this book quantifies the current absence of pregnant women in drug studies and identifies ethical issues, barriers, litigation fears and opportunities. Those in the pharmaceutical industry, IRB members who approve or deny drug study plans, doctors, nurses and midwives working in obstetrics or involved in conducting studies at their institutions will find this book an essential resource.

  • Epigenetics and Regeneration

    • 1st Edition
    • Volume 11
    • English
    Epigenetics and Regeneration compiles the first foundational reference on epigenetic mechanisms governing tissue development, repair, homeostasis, and regeneration, as well as pathways to employ these mechanisms in clinical practice and translational science. In this book, life science researchers, clinicians, and students will discover an interdisciplinary resource bringing together common themes in the field, background overviews, research methods, recent advances, and opportunities for drug discovery. Throughout this volume, special attention is paid to pre-clinical and first clinical studies aimed at increasing the regenerative potential of damaged tissues by epigenetic drugs, as well as innovative, discipline spanning strategies to enhance cell reprogramming. As an all-inclusive, evidence-based volume, Epigenetics and Regeneration will stimulate discussion and boost new research in this fascinating and impactful area of translational epigenetics.

  • Trends in Personalized Nutrition

    • 1st Edition
    • Charis M. Galanakis
    • English
    Trends in Personalized Nutrition explores the topic of personalized nutrition from multiple angles, addressing everything from consumer acceptance, to policies and cognitive dissonance. Sections in the book cover epigenetics, nutrigenomics, predicting glycemic response, and metabolomics and the role of bacteria. In addition, the book explores diet, obesity and personalized nutrition for athletes, women, and infants and children, along with a section on the role of modern technology in the promotion of personalized nutrition. Nutritionists, food technologists, food chemists, new product developers, academics, and researchers and physicians working in the field of nutrition will find this to be a great reference.

  • Advances in Applied Microbiology

    • 1st Edition
    • Volume 107
    • Geoffrey M. Gadd + 1 more
    • English
    Advances in Applied Microbiology, Volume 107, continues the comprehensive reach of this widely read and authoritative review source in microbiology. Users will find invaluable references and information on a variety of areas, with this updated volume including chapters covering the roles and applications of siderophores, biological oxidation of iron sulphides, production of biomass and biofuel feedstocks from microalgae, advances in the microbial ecology of biohydrometallurgy, bacterial synthesis of Se nanoparticles, and siderophores in environmental research, amongst other discussions.

  • Chemical and Synthetic Biology Approaches to Understand Cellular Functions - Part A

    • 1st Edition
    • Volume 621
    • English
    Chemical and Synthetic Biology Approaches to Understand Cellular Functions - Part A, Volume 621, the latest release in the Methods in Enzymology series, highlights new advances in the field, with this volume covering Site-directed ethylation of membrane proteins for measuring conformational transitions in lipid bilayers, the Design and synthesis of fluorescent activity probes for protein phosphatases, Stains, Utilizing split-nanoLuc fragments as luminescent probes for protein solubility in living cells, SH2-domain based sensor for intracellular recognition of sulfo-tyrosine, DNA-encoded immunoglobulins for detection of parasites, An engineered TEV protease – calmodulin fusion based sensor for neuronal calcium recording, and much more.

  • Advances in Agronomy

    • 1st Edition
    • Volume 156
    • English
    Advances in Agronomy, Volume 156, continues to be recognized as a leading reference and first-rate source for the latest research in agronomy. Each volume contains an eclectic group of reviews by leading scientists throughout the world. As always, the subjects covered are rich, varied, and exemplary of the abundant subject matter addressed by this long-running serial.

  • Advances in Microbial Physiology

    • 1st Edition
    • Volume 74
    • English
    Advances in Microbial Physiology, Volume 74, the latest release in this ongoing series, continues the long tradition of topical, important, cutting-edge reviews in microbiology. The book contains updates in the field, with comprehensive chapters covering The electrifying physiology of Geobacter bacteria 30 years on, Adaptive morphogenesis in bacteria, Bacterial energetics and respiratory metabolism, Bacteria respiration during infection, Regulation of Organohalide Respiration, Bioenergetics of Campylobacter jejuni, Formate Hydrogenlyases, Bioenergetical Aspects of the Bacterial and Archaeal Hydrogen Metabolism, and more.

  • New Developments in Nanosensors for Pharmaceutical Analysis

    • 1st Edition
    • Sibel A. Ozkan + 1 more
    • English
    New Developments for Nanosensors in Pharmaceutical Analysis presents an overview of developments in nanosensor usage in pharmaceutical analysis, thereby helping pharmaceutical companies attain reliable, precise, and accurate analysis of pharmaceuticals. This book presents very simple, precise, sensitive, selective, fast, and relatively inexpensive methods for pre-treatment, prior to analysis. These methods may be considered for further application in clinical studies and assays. The book includes the manufacturing of sensors for pharmaceutical analysis at nano- or smaller scales, and gives simple and relatable designs for the fabrication of sensors. Twelve chapters cover an introduction to the topic, immobilization techniques, mechanism effect of nanomaterials on structure, optical nanosensors for pharmaceutical detection, chemical nanosensors in pharmaceutical analysis, noble metal nanoparticles in electrochemical analysis of drugs, photo-electrochemica... nanosensors for drug analysis, molecularly imprinted polymer based nanosensors for pharmaceutical analysis, nanomaterials for drug delivery systems, nanomaterials enriched nucleic acid-based biosensors, nanosensors in biomarker detection, and nanomaterials-based enzyme biosensors for electrochemical applications.

  • Wilson Disease

    Pathogenesis, Molecular Mechanisms, Diagnosis, Treatment and Monitoring
    • 1st Edition
    • Karl Heinz Weiss + 1 more
    • English
    Wilson Disease: Pathogenesis, Molecular Mechanisms, Diagnosis, Treatment and Monitoring translates both clinical and experimental findings into a comprehensive approach for anyone involved in research and patient care. While the clinical variability of Wilson Disease poses a challenge from a diagnostic approach, the book uses the translational impact of new research findings to relate to new treatment concepts. Comprehensive chapters include common knowledge, guideline consensus statements, and discussions of clinical evidence. This is a must-have reference for researchers and clinicians in translational research.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 90
    • English
    Advances in Clinical Chemistry, Volume 90, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry, and is the benchmark for novel analytical approaches in the clinical laboratory.

  • Nanotechnology

    • 1st Edition
    • Volume 46
    • English
    Nanotechnology, Volume 46, the latest release in the Methods in Microbiology series, contains review articles on the application of nanotechnology in various fields of microbiology, including environmental microbiology, food microbiology and medical microbiology. Chapters in this new release include discussions on the Biosynthesis of Nanomaterials Utilizing Biomacromolecules, Nanotechnology in Medical Biology – Application of Nanodiagnostics in Infectious Diseases, Applications of Nanotechnology in Food Microbiology, Biosynthesis of Nanomaterials Utilizing Microorganisms, Nanotechnology in Medical Biology – Interaction of Pathogens and Nanostructured Surfaces, Biocompatible Polymers: Synthesis Methods, Surface Functionalization and its Biomedical Applications, and The Bacterial Flagellum.

  • International Review of Cell and Molecular Biology

    • 1st Edition
    • Volume 346
    • English
    International Review of Cell and Molecular Biology, Volume 346, reviews and details current advances in cell and molecular biology. The IRCMB series has a worldwide readership, maintaining a high standard by publishing invited articles on important and timely topics that are authored by prominent cell and molecular biologists. Sections in this new release include the karyosphere (karyosome) and its peculiar structure of the oocyte nucleus, organoids as models of disease, lipid droplets as organelles, the dark side of apoptosis, interconnections between autophagy and secretion, and the regulation and function of intracellular pressure in cell biology.

  • Advances in Insect Physiology

    • 1st Edition
    • Volume 56
    • English
    Advances in Insect Physiology, Volume 56, provides readers with the latest interdisciplinary reviews on the topic. It is an essential reference source for invertebrate physiologists, neurobiologists, entomologists, zoologists, and insect chemists, with this new release focusing on the Effects of resource limitation on the strengths of tradeoffs in insect lifecycles, The circadian system in insects: cellular, molecular, and functional organization, Molecular Physiology of the Insect Midgut, The Cryptonephridic system in Lepidoptera, Subsocial insects and the physiology of parental care, Mechanisms regulating phenotypically plastic traits in wing polymorphic insects, and more.

  • Paxinos and Franklin's the Mouse Brain in Stereotaxic Coordinates, Compact

    The Coronal Plates and Diagrams
    • 5th Edition
    • Keith B.J. Franklin + 1 more
    • English
    Paxinos and Franklin's The Mouse Brain in Stereotaxic Coordinates, Compact Fifth Edition, is the compact version of the most widely used and cited atlas of the mouse brain in print. It emulates in design and accuracy Paxinos and Watson’s The Rat Brain in Stereotaxic Coordinates, the most cited publication in neuroscience. The compact edition provides the coronal plates and diagrams of the full mouse atlas in a smaller, more convenient spiral format and at a student friendly price. High resolution digital photographs of the coronal plane of section from the full 5th edition complement the coronal drawings. Unique to the compact, it includes an introduction to the use of the atlas in stereotaxic surgery.

  • Transgenerational Epigenetics

    • 2nd Edition
    • Volume 13
    • English
    Transgenerational Epigenetics, Second Edition, offers the only up-to-date, comprehensive analysis of the inheritance of epigenetic phenomena between generations with an emphasis on human disease relevance, drug discovery, and next steps in clinical translation. International experts discuss mechanisms of epigenetic inheritance, its expression in animal and plant models, and how human ailments, such as metabolic disorders and cardiovascular disease are influenced by transgenerational epigenetic inheritance. Where evidence is sufficient, epigenetic clinical interventions are proposed that may help prevent or reduce the severity of disease before offspring are born. This edition has been thoroughly revised in each disease area, featuring newly researched actors in epigenetic regulation, including long noncoding RNA in addition to histone modifications and DNA methylation. Therapeutic pathways in treating cancer and extending human longevity are also considered, as are current debates and future directions for research.

  • Protein Modificomics

    From Modifications to Clinical Perspectives
    • 1st Edition
    • Tanveer Ali Dar + 1 more
    • English
    Protein Modificomics: From Modifications to Clinical Perspectives comprehensively deals with all of the most recent aspects of post-translational modification (PTM) of proteins, including discussions on diseases involving PTMs, such as Alzheimer’s, Huntington’s, X-linked spinal muscular atrophy-2, aneurysmal bone cyst, angelman syndrome and OFC10. The book also discusses the role PTMs play in plant physiology and the production of medicinally important primary and secondary metabolites. The understanding of PTMs in plants helps us enhance the production of these metabolites without greatly altering the genome, providing robust eukaryotic systems for the production and isolation of desired products without considerable downstream and isolation processes.

  • Sweet Potato

    Chemistry, Processing and Nutrition
    • 1st Edition
    • Taihua Mu + 1 more
    • English
    Sweet Potato: Chemistry, Processing, and Nutrition presents foundational information, including identification, analysis, and use of chemical components from sweet potato in a variety of food and nonfood uses. Sweet potatoes can be easily propagated, are rich source of carbohydrates and functional components, and are highly productive, which makes them most suitable for production of staple and functional foods. With the increasing population and the challenges of providing healthy food to the world, there is an increasing consumer demand for new and better sweet potato products, particularly for those in developing countries. Providing a brief description of the specific sweet potato components, their role during processing and strategies for quality optimization, this book also explores novel methods of sweet potato starch, protein, and pectin modification providing students, researchers, and technologists working in the area of food science and others with the most recent information and state-of-the-art technology for developing new and beneficial uses of sweet potato.

  • Mitochondrial Medicine

    A Primer for Health Care Providers and Translational Researchers
    • 1st Edition
    • Pankaj Prasun
    • English
    Mitochondrial Medicine: A Primer for Health Care Providers and Translational Researchers is an applied, holistic resource that addresses the evolving and multidisciplinary area of mitochondrial disease. The book discusses the fundamentals of mitochondrial medicine in humans, as well as the pathophysiology, diagnosis and treatment of mitochondrial diseases. Three all-inclusive sections examine the role of mitochondria in common medical conditions, such as diabetes, heart failure and the full range of inherited mitochondrial diseases. Sections cover the genetic and biochemical basis of both mitochondrial DNA deletion syndromes and point mutation syndromes, their clinical presentation, treatment plans, genetic counseling, prenatal testing, and ongoing research. While providing a solid foundation in its topic area, each chapter in the book is written in an accessible format with illustrative case studies, thus making it a quick bedside or clinical laboratory reference.

  • Neural Network Modeling and Identification of Dynamical Systems

    • 1st Edition
    • Yury Tiumentsev + 1 more
    • English
    Neural Network Modeling and Identification of Dynamical Systems presents a new approach on how to obtain the adaptive neural network models for complex systems that are typically found in real-world applications. The book introduces the theoretical knowledge available for the modeled system into the purely empirical black box model, thereby converting the model to the gray box category. This approach significantly reduces the dimension of the resulting model and the required size of the training set. This book offers solutions for identifying controlled dynamical systems, as well as identifying characteristics of such systems, in particular, the aerodynamic characteristics of aircraft.

  • EEG-Based Experiment Design for Major Depressive Disorder

    Machine Learning and Psychiatric Diagnosis
    • 1st Edition
    • Aamir Saeed Malik + 1 more
    • English
    EEG-Based Experiment Design for Major Depressive Disorder: Machine Learning and Psychiatric Diagnosis introduces EEG-based machine learning solutions for diagnosis and assessment of treatment efficacy for a variety of conditions. With a unique combination of background and practical perspectives for the use of automated EEG methods for mental illness, it details for readers how to design a successful experiment, providing experiment designs for both clinical and behavioral applications. This book details the EEG-based functional connectivity correlates for several conditions, including depression, anxiety, and epilepsy, along with pathophysiology of depression, underlying neural circuits and detailed options for diagnosis. It is a necessary read for those interested in developing EEG methods for addressing challenges for mental illness and researchers exploring automated methods for diagnosis and objective treatment assessment.

  • Sports and Energy Drinks

    Volume 10: The Science of Beverages
    • 1st Edition
    • Alexandru Grumezescu + 1 more
    • English
    Sports and Energy Drinks, Volume 10 in The Science of Beverages series, is the first single-volume resource to focus on the science behind these beverages-for-purpos... products. As consumers seek ways to effectively replenish key nutrients after strenuous activity—while also balancing calories and vitamin intake—sports and energy drinks is one of the fastest growing markets in the industry. From protein to fruit, athlete to adolescent consumption, this book explores the key issues and challenges in developing products that meet consumer demand in a safe-and-effective manner. This series takes a multidisciplinary approach to help research and development professionals understand the scientific complexities of these unique beverages. As demand for sports and energy drinks is growing and with a more competitive market, this timely and useful resource will equip industry professionals with the tools they need to create new and innovative health-promoting products.

  • Netter's Neurology

    • 3rd Edition
    • Jayashri Srinivasan + 3 more
    • English
    Perfect for residents, medical students, generalists, nurses, and other healthcare professionals who need a practical, working knowledge of neurology, Netter's Neurology, 3rd Edition, provides a concise overview highlighted by unique, memorable Netter illustrations. This award-winning visual resource showcases the well-known work of Frank H. Netter, MD, and his successor, Carlos Machado, MD, a physician who has created clear, full-color illustrations in the Netter tradition.

  • New Approaches for Flavin Catalysis

    • 1st Edition
    • Volume 620
    • English
    New Approaches for Flavin Catalysis, Volume 620, a new volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Topics covered in this update include Anaerobiosis and Methods for Reduction, Reduction Potentials, Anaerobic Stopped-Flow, No Glove-Box, Anaerobic Stopped-Flow, in a Glove-Box, Chemical Quenching, Oxygen Reactions, Double-mixing Stopped-Flow, Kinetic Isotope Effects and Viscosity Effects, Heavy Enzymes Synthetic Flavins & Linear Free Energy Relationships, Vibrational Spectroscopy, Stark Spectroscopy, EPR and Related Methods, Molecular Dynamics, Phylogenetic Relationships/Superf... O2 and Superoxide Analogs, and more.

  • Sleep Deprivation and Cognition

    • 1st Edition
    • Volume 246
    • English
    Sleep Deprivation and Cognition, Volume 247, the latest release in the Progress in Brain Research series, covers the effects of sleep deprivation, with this new release featuring sections on the Impact of sleep deprivation on long-term memory, Adolescent sleep restriction effects on cognition and mood, Self- regulation and social behavior during sleep deprivation, Experiential decision-making and the effects of sleep loss, Sleep deprivation and dynamic attentional control, a Pharmacogenetic approach to understanding sleep deprivation and cognition, Neuroimaging of functional connectivity in the sleep-deprived brain: what does it tell us?, and more.

  • Telemedicine Technologies

    Big Data, Deep Learning, Robotics, Mobile and Remote Applications for Global Healthcare
    • 1st Edition
    • D. Jude Hemanth + 1 more
    • English
    Telemedicine Technologies: Big Data, Deep Learning, Robotics, Mobile and Remote Applications for Global Healthcare illustrates the innovative concepts, methodologies and frameworks that will increase the feasibility of the existing telemedicine system. The book also focuses on showcasing prototypes of remote healthcare systems, thus emphasizing the data processing side that is often recognized as the backbone of any telemedicine system.

  • 250 examens de laboratoire

    en pratique médicale courante
    • 13th Edition
    • René Caquet
    • French
    Les examens de laboratoire, parfois qualifiés d’examens «complémentaires» alors qu’ils sont indispensables, recherchent bactéries et virus, reconnaissent les cellules anormales, détectent les anticorps, évaluent le fonctionnement des organes, scrutent le milieu intérieur, examinent les gènes.Comment s’en passer ?Ce livre, élaboré par un clinicien, offre aux professionnels de santé un instrument de pratique quotidienne. Ouvrage de référence, il expose tout ce qu’il faut savoir pour prescrire des analyses médicales et interpréter les résultats.Les examens de laboratoire sont présentés sous forme de fiches, classées par ordre alphabétique, qui suivent un plan récurrent : mode et précautions de prélèvement, valeurs normales et cliniques (valeurs pathologiques), objectifs de l’examen et interprétation.Cet ouvrage décrit le raisonnement qui permet de déduire d’un résultat biologique les meilleures conclusions diagnostiques ou thérapeutiques possibles, en interprétant les résultats à la lumière de la clinique, de la littérature scientifique et des données de santé publique.Cette 13e édition est entièrement actualisée, notamment en fonction des publications récentes, des recommandations des sociétés savantes (VIH, allergies, auto-immunité...) et en accord avec la nomenclature de la Sécurité sociale.De nouveaux examens liés à l’actualité médicale (caryotype onco-hématologique, hématocrite, hépatite E…) sont ajoutés.L’ouvrage s’accorde volontairement à la pratique des généralistes, spécialistes et biologistes. Les examens plus rares (biologie moléculaire…) sont traités en accord avec la demande.

  • Inspiring Conversations with Women Professors

    The Many Routes to Career Success
    • 1st Edition
    • Anna Garry
    • English
    Inspiring Conversations with Women Professors: The Many Routes to Career Success provides stories behind the many paths to professorship taken by these featured women. It includes information on their diverse life stories and how they navigated the beginning, middle stages, and other parts of their careers, including unexpected paths, support and how they got hooked by science/their field. In addition, they discuss why they chose this career, the obstacles they encountered, and how they found a way forward. Each interview encapsulates the advice and practical solutions they give.

  • Sherpath for Nutrition (Grodner Version)

    • 7th Edition
    • Elsevier Inc
    • English
    For today’s healthcare students, Sherpath is the learning tool that takes primary course content and gives you what you need to know now, in the time you have available, to achieve success tomorrow. It then adapts based on your personal interactions and responds by building on the topics and concepts where you need help. Sherpath brings content to life by integrating the core content to a digital environment and complementing it with videos, images, case studies, and micro simulations on a single platform. This version of Sherpath fully incorporates ebook content.

  • Les troubles du sommeil

    • 3rd Edition
    • Yves Dauvilliers
    • French
    La médecine du sommeil est une discipline récente et les manuels qui lui sont consacrés sont peu nombreux. Les troubles du sommeil et de l’éveil touchent pourtant une part importante de la population et ont de graves répercussions sur la santé physique et mentale, ainsi que sur la qualité de vie.La 3e édition de cet ouvrage de référence, entièrement mis à jour et agrémenté de questionnaires, d’échelles et d’un glossaire étendu :• fait le point sur le sommeil normal (aspects neurobiologiques et physiologiques chez l’enfant, l’adulte et le sujet âgé),• présente les différentes méthodes d’exploration,• propose une synthèse sur les multiples troubles (insomnie, hypersomnie, troubles du rythme circadien, parasomnie…),• établie le lien entre les troubles du sommeil et les spécialités médicales : neurologie, cardiologie, pneumologie, endocrinologie, pédiatrie, psychiatrie, ORL….Cet ouvrage s’adresse aux médecins généralistes et spécialistes. Ils y trouveront des réponses à leurs questions, ainsi que de nombreuses indications pour la prise en charge des patients et la prescription de traitements. Il s’adresse également à tous les professionnels de santé, chercheurs et étudiants désireux de s’ouvrir à un domaine encore peu enseigné dans les facultés et écoles.

  • Progress in Molecular Biology and Translational Science

    Glycans and Glycosaminoglycans as Clinical Biomarkers and Therapeutics - Part B
    • 1st Edition
    • Volume 163
    • English
    Glycans and Glycosaminoglycans as Clinical Biomarkers and Therapeutics - Part B, Volume 163 in the Progress in Molecular Biology and Translational Science series, provides informative monographs on a variety of research topics related to Glycans and glycosaminoglycans as clinical biomarkers and therapeutics. Topics in this update include an Overview of Fugal Glycan-based Therapeutics, Heparin: An Essential Drug for Modern Medicine, Low Molecular Weight Heparins and Their Clinical Applications, The Clinical Use of Fondaparinux: A Synthetic Heparin Pentasaccharid, Heparinoids as Clinically Used Drugs, Marine Glycan-Derived Therapeutics in China, Efficacy of Heparinoid PSS in Treating Cardiovascular and other Diseases—30 Years Clinical Applications in China, and more.

  • Intracellular Signalling Proteins

    • 1st Edition
    • Volume 116
    • English
    Intracellular Signalling Proteins, Volume 116, presents an overview of the current developments in mechanisms of intracellular signaling and involvement of these mechanisms in the development of a number of disorders and diseases. Opportunities for targeting the intracellular signaling cascades for benefiting patients are also discussed, along with chapters that focus on Voices from the Dead: The Complex Language of Dead Cells, Nucleobindins and Encoded Peptides: From Cell Signalling to Physiology, Estrogen Receptor Signaling Mechanisms, Intracellular Signaling of the AMP-Activating Protein Kinase, the Relationship between Mitofusin 2 and Cancer, Molecular Signaling in Bone Cells: Regulation Cell Differentiation and Survival, and more.

  • Evolution's Clinical Guidebook

    Translating Ancient Genes into Precision Medicine
    • 1st Edition
    • Jules J. Berman
    • English
    Evolution's Clinical Guidebook: Translating Ancient Genes into Precision Medicine demonstrates, through well-documented examples, how an understanding of the phylogenetic ancestry of humans allows us to make sense out of the flood of genetic data streaming from modern laboratories and how it can lead us to new ways to prevent, diagnose and treat diseases. Topics cover evolution and human genome, meiosis and other recombinants events, embryology, speciation, phylogeny, rare and common diseases, and the evolution of aging. This book is a valuable source for bioinformaticians and those in the biomedical field who need knowledge, down to gene level, to fully comprehend currently available data.

  • Advances in Parasitology

    • 1st Edition
    • Volume 104
    • David Rollinson + 1 more
    • English
    Advances in Parasitology, Volume 104, the latest in a series first published in 1963, contains comprehensive reviews on all areas of interest in contemporary parasitology. The series includes medical studies of parasites of major influence, along with reviews of more traditional areas, such as zoology, taxonomy, and life history, which help to shape current thinking and applications. This new release includes sections on Leishmania Tropica, Extracellular Vesicles in Host-Parasite Interaction, Cathepsins and Vaccines for Fascioliosis, Echinococcosis Transmission on the Tibetan Plateau, A Review of Diagnostics for STH from a Public Health Perspective, and Zoonotic Transmission of Intestinal Parasites: Implications for Control and Elimination.

  • The Comorbidities of Epilepsy

    • 1st Edition
    • Marco Mula
    • English
    Epilepsy is one of most frequent neurological disorders affecting about 50 million people worldwide and 50% of them have at least another medical problem in comorbidity; sometimes this is a the cause of the epilepsy itself or it is due to shared neurobiological links between epilepsy and other medical conditions; other times it is a long-term consequence of the antiepileptic drug treatment. The Comorbidities of Epilepsy offers an up-to-date, comprehensive overview of all comorbidities of epilepsy (somatic, neurological and behavioral), by international authorities in the field of clinical epileptology, with an emphasis on epidemiology, pathophysiology, diagnosis and management. This book includes also a critical appraisal of the methodological aspects and limitations of current research on this field. Pharmacological issues in the management of comorbidities are discussed, providing information on drug dosages, side effects and interactions, in order to enable the reader to manage these patients safely. The Comorbidities of Epilepsy is aimed at all health professionals dealing with people with epilepsy including neurologists, epileptologists, psychiatrists, clinical psychologists, epilepsy specialist nurses and clinical researchers.

  • Advances in Agronomy

    • 1st Edition
    • Volume 155
    • Donald L. Sparks
    • English
    Advances in Agronomy, Volume 155, the newest release in this valuable serial, continues to be recognized as a leading reference and first-rate source for the latest research in agronomy. Each volume contains an eclectic group of reviews by leading scientists throughout the world. As always, the subjects covered are rich, varied and exemplary of the abundant subject matter addressed by this long-running serial.

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