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Books in Toxicology

Elsevier's Toxicology collection provides essential insights for researchers and scientists into mitigating the adverse effects of contaminants on organisms, covering research, analysis, risk assessment, detection, prevention, diagnosis, and treatment of toxic exposure. Including toxicity testing, environmental toxicology it offers valuable knowledge for addressing public health and safety challenges by examining the adverse effects of contaminants on human health, animals, and the environment.

    • Diuretic Agents

      • 1st Edition
      • September 4, 1997
      • Donald W. Seldin + 1 more
      • English
      • Hardback
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      • eBook
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      The only comprehensive work to cover all aspects of diuretic agents, the book discusses the pharmacology and toxicology of diuretic agents as well as the physiological effects. Experts in the field present the principles and experimental approaches for the study of interactions between pharmacologic compounds in relation to specific target organs. Diuretic Agents contains information on the mechanisms of action and application of diuretics, and details FDA regulations and pharmaceutical industry guidelines.
    • Human Toxicology

      • 1st Edition
      • September 2, 1996
      • J. Descotes
      • English
      • eBook
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      This excellent volume was designed and edited with two major ideas in mind: firstly, the field of clinical toxicology is changing and an acknowledgement of these changes is warranted; secondly, no comprehensive compilation of recently published case reports of, and clinical studies on, human poisonings is available, which is in sharp contrast to the closely related field of drug-induced side-effects.The book focusses on issues of recent concern, or issues poorly documented in the past. It is important that clinical toxicologists gain a better knowledge of all the available techniques of toxicological analysis. A better understanding of the way a sound interpretation of results should be conducted for the benefit of the patient's management, and a comprehensive set of data on the kinetics of the most common pharmaceutical drugs and many chemicals is required.Human Toxicology is a timely reference work which will be welcomed by a broad audience of toxicology professionals.
    • In Vitro Methods in Pharmaceutical Research

      • 1st Edition
      • October 4, 1996
      • Jose V. Castell + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 1 6 3 3 9 0 5
      • eBook
        9 7 8 0 0 8 0 5 3 4 6 0 2
      In Vitro Methods in Pharmaceutical Research provides a comprehensive guide to laboratory techniques for evaluating in vitro organ toxicity using cellular models. Step-by-step practical tips on how to perform and interpret assays for drug metabolism and toxicity assessment are provided, along with a comparison of different techniques available. It is a welcome addition to the literature at a time when interest is growing in cellular in vitro models for toxicology and pharmacology studies.
    • Loomis's Essentials of Toxicology

      • 4th Edition
      • March 1, 1996
      • A. Wallace Hayes + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 3 9 9 2 4 1 3
      • Hardback
        9 7 8 0 1 2 4 5 5 6 2 5 6
      • eBook
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      Loomis's Essentials of Toxicology is an introductory text on the science of harmful biologic effects associated with exposures to chemicals of all types. The scope of this book includes a discussion of the major types of chemicals involved; the general properties of chemicals and biologic systems as they influence the occurrence of detrimental biologic effects; the methods used to demonstrate these effects; and the basis for clinical diagnosis and therapy of harmful effects of chemicals on humans. Individual examples are used to demonstrate each of the principles under discussion. This text is an invaluable resource for toxicologists as well as a comprehensive introduction to the topic for graduate and advanced undergraduate students in toxicology and public health.
    • Endocrine Methods

      • 1st Edition
      • March 11, 1996
      • Bozzano G Luisa
      • English
      • Paperback
        9 7 8 0 1 2 3 9 0 7 7 3 8
      • eBook
        9 7 8 0 0 8 0 5 3 0 8 9 5
      Endocrine Methods contains descriptions of contemporary and cutting-edge methodologies in various areas of endocrinology, including receptor theory and immunologic techniques for endocrine research. The book presents step-by-step procedures easily available to study the endocrine system and includes experts in their respective fields as contributors. The book presents step-by-step procedures for many important areas of endocrine target organs.Endocrine Methods serves as a valuable methodological resource for investigators using endocrine methods.
    • Biochemistry, Molecular Biology, and Therapeutic Implications

      • 1st Edition
      • Volume 34
      • November 29, 1995
      • English
      • Paperback
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      Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular bases of drug action, both applied and experimental. This volume contains chapters that address diverse but interrelated areas pertaining to the chemistry, biochemistry, molecular biology, and pharmacology of nitric oxide in mammalian cells. The contents form a comprehensive treatise of factors influencing the control of nitric oxide production in various cell types.
    • Advances in Pharmacology

      • 1st Edition
      • Volume 30
      • September 27, 1994
      • English
      • Hardback
        9 7 8 0 1 2 0 3 2 9 3 1 1
      • Paperback
        9 7 8 0 1 2 3 9 9 4 1 0 3
      • eBook
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      Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular basis of drug action, both applied and experimental.
    • Biological Effects of Electric and Magnetic Fields

      • 1st Edition
      • June 15, 1994
      • David O. Carpenter + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 3 9 5 7 7 9 5
      • Hardback
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      Recent concerns over the possible hazards of electrical and magnetic fields in the home and workplace are comprehensively addressed within this book. The chapters contain detailed research on the biological effects of electric and magnetic fields, and evidence for and against any interaction of electromagnetic fields (EMFs) and biological systems.
    • Biological Effects of Electric and Magnetic Fields

      • 1st Edition
      • June 15, 1994
      • David O. Carpenter + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 1 6 0 2 6 2 8
      • Paperback
        9 7 8 0 1 2 3 9 5 7 8 0 1
      • eBook
        9 7 8 0 0 8 0 8 8 6 8 8 6
      Recent concerns over the possible hazards of electrical and magnetic fields in the home and workplace are comprehensively addressed within this book. The chapters contain detailed research on the biological effects of electric and magnetic fields, and evidence for and against any interaction of electromagnetic fields (EMFs) and the biological systems.
    • In Vitro Toxicity Indicators

      • 1st Edition
      • Volume 1B
      • April 25, 1994
      • Charles A. Tyson
      • English
      • Hardback
        9 7 8 0 1 2 4 6 1 2 0 3 7
      • eBook
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      About the Series:In the tradition of Methods in Enzymology and Methods in Neurosciences, Academic Press is pleased to announce a new serial: Methods in Toxicology. There is a pressing need among researchers involved in toxicologic investigation for a series of publications that organizes and presents information on the latest experimental methodologies. To address the needs of researchers in toxicology, toxicologic pathology, pharmacology, and clinical biochemistry, this new serial provides comprehensive descriptions of state-of-the-art methods for evaluating drug and chemical toxicity. Thematic volumes focus on mechanistic approaches to the study of toxicity both in vitro and in vivo, taking advantage of the recent advances in the biological and chemical sciences that allow closer scrutiny of the mechanisms by which agents cause damage. Each volume begins with an introductory chapter that offers a broad guide to the application of methods addressed in that volume. Subsequent chapters contain detailed descriptions of research protocols, accessible both to experts and those new to toxicologic investigation. Included in each chapter are clearly defined procedures, discussions of limitations of the method, comparative considerations (species, sex, strain), interpretations of results, and explanations of how the methods may serve as alternatives to in vivo testing. Each volume of Methods in Toxicology is available in case binding for the library and Wire-O-binding for the laboratory. About the Book:Concurrent with the development of biological systems for in vitro toxicologic investigations (Volume 1A-In Vitro Biological Systems), techniques have evolved to detect and evaluate the diverse effects produced when toxicants interact with these systems. This volume describes methods for detecting and quantifying pertubations in various cellular parameters related to cell dysfunction and death (including apoptosis) associated with adverse toxicant action. Each endpoint measurement probes one aspect of the response of the biological system to a toxicant. When several techniques are used in combination, it is possible to derive a more complete understanding of the mechanism of toxicity at the cellular, tissue, or organ level. The methods collected here are organized by major categories of toxic effects, such as membrane damage, disruption of energy metabolism, and lipid peroxidation, commonly monitored by toxicologists during a comprehensive toxicity study. Specialized techniques of interest and value in mechanistic investigations are included. As with the first volume, the goal is not to obtain an exhaustive collection of methods, but rather to assemble in a single central reference a set of valuable techniques that are used for toxicologic investigations, along with cautionary remarks on their use and limitations.