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Books in Toxicology

Elsevier's Toxicology collection provides essential insights for researchers and scientists into mitigating the adverse effects of contaminants on organisms, covering research, analysis, risk assessment, detection, prevention, diagnosis, and treatment of toxic exposure. Including toxicity testing, environmental toxicology it offers valuable knowledge for addressing public health and safety challenges by examining the adverse effects of contaminants on human health, animals, and the environment.

BooksJournals
141-150 of 389 results in All results

Electrocardiography of Laboratory Animals

  • 1st Edition
  • November 22, 2013
  • Jeffrey W. Richig + 1 more
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 4 1 5 9 3 6 - 5
  • eBook
    9 7 8 - 0 - 1 2 - 4 1 5 9 9 9 - 0
Electrocardiography of Laboratory Animals is the only book covering electrocardiography of laboratory animals, including dogs, mini-pigs, and cynomologus monkeys. As more countries institute requirements for the care of laboratory animals in research, this publication offers an effective standard on performing and analyzing ECGs. Topics covered include safety electrocardiography, toxicology, safety pharmacology, and telemetry. Electrocardiography of Laboratory Animals will assist biological and medical researchers, veterinarians, zoologists, and students in understanding electrocardiography of various species of animals used in research.

Bacterial Endotoxins

  • 1st Edition
  • November 15, 2013
  • Solomon Kadis + 2 more
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 2 - 1 5 8 9 - 1
Microbial Toxins, Volume V: Bacterial Endotoxins covers the physiology, pathology, and immunology of bacterial endotoxins. The book discusses the relationship of lipopolysaccharide structure to bacterial virulence; the importance of blood-group and Forssman antigenic determinants in interactions between human and microbes; and the chemical modification of endotoxin and inactivation of its biological properties. The text also describes the effects of endotoxic lipopolysaccharides on the complement system; the host-dependent detoxification of bacterial endotoxin; and the metabolic effects of bacterial endotoxins. The release of vasoactive agents and the vascular effects of endotoxin are also considered. The book further tackles the febrile response to endotoxin; some major aspects and the relationship between shock and endotoxemia; as well as the effects of lipopolysaccharides (endotoxins) on the susceptibility to infections. The text also encompasses the role of hypersensitivity and tolerance in reactions to endotoxins. Pathologists, immunologists, physiologists, and microbiologists will find the book invaluable.

Chemotherapy

  • 1st Edition
  • November 13, 2013
  • M. Adolphe
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 1 - 8 8 6 0 - 7
Advances in Pharmacology and Therapeutics, Volume 10: Chemotherapy covers the proceedings of the 7th International Congress of Pharmacology. The title presents papers that detail the advancement of pharmacological research in chemotherapy. The text first covers the chemotherapy of schistosomiasis. Next, the selection presents the trends in malaria and cancer chemotherapy, along with their pharmacological research. The text also details the use of cell cultures as tools in pharmacological investigations. The book will be of great interest to pharmacologists and oncologists.

The Prostaglandins

  • 1st Edition
  • November 13, 2013
  • M. F. Cuthbert
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 1 - 9 2 8 0 - 2
The Prostaglandins: Pharmacological and Therapeutic Advances provides a concise account of the more important theoretical developments and areas in which the prostaglandins are being introduced into clinical practice or have potential clinical application. Chapters I to IV of this book deal with the chemistry and classification, distribution and metabolism, general pharmacology, and mechanism of action. The rest of the chapters discuss the relationship of the prostaglandins to the reproductive, cardiovascular, respiratory, and gastro-intestinal systems with an emphasis on the human pharmacology and potential therapeutic applications. This text also includes the speculations and suggestions of contributors regarding the possible and further use of the prostaglandins. This publication is a good reference for biochemists and medical students concerned with the potential of prostaglandins.

Drugs, Alcohol and Tobacco in Britain

  • 1st Edition
  • November 13, 2013
  • Jim Zacune + 1 more
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 1 - 9 3 0 9 - 0
Drugs, Alcohol, and Tobacco in Britain focuses on the use and misuse of drugs, alcohol, and tobacco and the British response to these substances. The manuscript first tackles alcohol production, sale, and control and production of drugs. Discussions focus on licensing laws in England and Wales, taxation, home brewing and distilling, detailed incidence of liquor duties, illicit production of alcoholic beverages, overseas trade, and tied-house system. The book then elaborates on the control of drugs, including international control, Dangerous Drugs Act, 1965, United Kingdom laws, and control of specific psycho-active drugs. The publication examines the "normal" use of alcohol in Great Britain, medical use of drugs, and a historical perspective of alcohol abuse in Great Britain. Topics include medical use of cannabis, amphetamines, and opiates, student drinking, medical use of alcohol, expenditure on alcohol, and alcohol consumption. The text then takes a look at the misuse of alcohol in Great Britain, non-medical use of cannabis, non-medical use of Lysergic Acid Diethylamide and hallucinogenic drugs, and non-medical use of hypnotics and tranquillizers. The book is a valuable source of information for readers wanting to study the use and abuse of drugs, alcohol, and tobacco in Great Britain.

Fungal Toxins

  • 1st Edition
  • October 30, 2013
  • Alex Ciegler + 2 more
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 2 - 1 5 9 0 - 7
Microbial Toxins, Volume VI: Fungal Toxins covers information on the evaluation of the chemical, biological, and biomedical aspects of the fungal toxins. The book discusses the historical structure chemistry, production, analysis, detoxification, biosynthesis, pharmacology, toxicology, and molecular biochemistry of aflatoxins and related compounds. The text also describes the isolation, analysis, production, chemistry, biological effects, and biogenesis of the ochratoxins, as well as the bioproduction, biosynthesis, and chemical properties of misclellaneous Aspergillus toxins. Various species of storage fungi, including yellowed rice toxins, luteoskyrin and related compounds, chlorine-containing compounds, citrinin, and citreoviridin are also considered. The book further tackles the physical and chemical properties and the biological activity of the rubratoxins; the biosynthesis and biochemical effects of patulin, penicillic acid, and other carcinogenic lactones; as well as the structure, production, biosynthesis, and biological effects of cyclopiazonic acid and related toxins. The text also encompasses bioproduction, properties, chemical structure, and biological activity of miscellaneous Penicillium toxins. Microbiologists, biochemists, epidemiologists, pharmacologists, toxicologists, medical students and people involved in other related fields will find the book useful.

Mechanisms of Drug Toxicity

  • 1st Edition
  • October 22, 2013
  • H. RaÅ¡ková
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 1 - 5 7 2 0 - 7
Mechanisms of Drug Toxicity, Volume 4 presents the proceedings of the 3rd International Pharmacological Meeting held in Sao Paulo, Brazil in 1966. The book discusses the drug-induced pathobiotic effects; the mechanisms of adverse reactions; and enzyme induction in the mechanism of chronic toxicity. The text also describes the influence of inducing substances on the growth of liver and microsomal electron transport systems; the quantitative aspects of chronic toxicity; and the facts and fallacies in predicting drug effects in human.

Pharmacology of the Coronary Circulation

  • 1st Edition
  • October 22, 2013
  • Natalia V. Kaverina
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 1 - 8 5 3 5 - 4
Pharmacology of the Coronary Circulation focuses on the effects of pharmacological substances on the circulation of the heart, physiology of coronary circulation, effects of adrenomimetic, cholinergic, and ganglion-blocking agents, phenothiazine derivatives, analgesics, nitrites, and nitrates on cardiac vessels and results of clinical trials on Chloracizine. The publication first offers information on the physiology of the coronary circulation and the effects of pharmacological substances on the coronary circulation, including myotropic and neutropic substances and other substances. The book then examines the effects of adrenomimetic substances and cholinergic substances on the coronary circulation. The manuscript evaluates the effects of ganglion-blocking substances and analgesic substances on the coronary circulation. Topics include nicotine, etraethylammonium, hexamethonium, pentamine, and mecamine. The publication then takes a look at the effects of phenothiazine derivatives on the coronary circulation; importance of reflex reactions in connection with the development of acute coronary insufficiency; and effects of pharmacological substances on reflex reactions in the coronary vessels. The book is a dependable reference for readers interested in the pharmacology of the coronary circulation.

Biochemical and Neurophysiological Correlation of Centrally Acting Drugs

  • 1st Edition
  • October 22, 2013
  • E. Trabucchi + 2 more
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 1 - 8 5 3 8 - 5
Section on Pharmacology of the International Union of Physiological Sciences (SEPHAR), Proceedings of the Second International Pharmacological Meeting, August 20-23, 1963, Volume 2: Biochemical and Neurophysiological Correlation of Centrally Acting Drugs focuses on the composition, reactions, and applications of centrally acting drugs. The selection first offers information on the physiology of striopallidum in relation to extrapyramidal function and disorders and actions of dopa and dopamine in relation to function of the central nervous system. Discussions focus on correlation of behavioral and clinical states with metabolism of dopamine, functions of dopamine in the brain, and the central pharmacology of dopamine. The text then examines the role of brain dopamine (3-hydroxytyramine) in Parkinsonism, including behavior of dopamine in the extrapyramidal centers in patients with Parkinson's disease; brain dopamine and the extrapyramidal symptomatology of Parkinson's disease; and parallelism between Parkinson's disease and the Parkinson-like state induced by reserpine in man. The publication ponders on pharmacological studies on tremorine and metabolism of tremorine. The manuscript also takes a look at the contribution on the pathophysiology of intentional tremor; failure of Antiparkinson drugs to antagonize hypothermia in tremorine-treated rats; and significance of dopamine in psychomotor stimulant action. The selection is a dependable source of data for readers interested in centrally acting drugs.

Recent Advances in the Pharmacology of Toxins

  • 1st Edition
  • October 22, 2013
  • H. W. Raudonat
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 1 - 5 6 6 3 - 7
Recent Advances in the Pharmacology of Toxins brings together the proceedings of the Second International Pharmacological Meeting of the International Union of Physiological Sciences, held in Prague, Czechoslovakia, on August 20-23, 1963. The meeting provided a forum for discussing advances in the understanding of the pharmacology of toxins and addressed topics ranging from antagonists of bradykinin to the mode of the spread of tetanus toxin in experimental animals. This volume is comprised of 28 chapters and begins with an analysis of the effects of toxins from microorganisms on mammalian cellular metabolism and structure, followed by a review of SRS-A, a slow-reacting substance of anaphylaxis, as a potential factor in the symptoms produced by venoms and toxins. Subsequent chapters explore the release of pharmacologically active lipids by enzymes contained in toxins; the structure and function of some enzymes in snake venoms, with reference to disulfide linkages; biochemistry and pharmacology of small-molecular compounds of cobra venom; and the role of ganglioside in the mode of action of tetanus toxin. This book will be of particular value to pharmacologists and physiologists.

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