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Books in Pharmacology

Elsevier's Pharmacology collection studies how drugs interact with biological systems to improve health and treat disease. It covers pharmacodynamics, exploring drug effects on biology, and pharmacokinetics, studying how the body affects drugs. Branches like Pharmacogenetics. Essential for pharmacologists, this collection offers invaluable insights into drug interactions, efficacy, and safety, crucial for advancing drug development and improving patient outcomes.

BooksJournals

    • Diagnostic Atlas of Gastroesophageal Reflux Disease

      • 1st Edition
      • July 11, 2007
      • Parakrama T. Chandrasoma
      • English
      • Paperback
        9 7 8 0 1 2 4 0 5 4 7 8 3
      • Hardback
        9 7 8 0 1 2 3 7 3 6 0 5 5
      • eBook
        9 7 8 0 0 8 0 8 7 8 0 3 4
      Gastroesophageal reflux is one of the most common maladies of mankind. Approximately 40% of the adult population of the USA suffers from significant heartburn and the numerous antacids advertised incessantly on national television represents a $8 billion per year drug market. The ability to control acid secretion with the increasingly effective acid-suppressive agents such as the H2 blockers (pepcid, zantac) and proton pump inhibitors (nexium, prevacid) has given physicians an excellent method of treating the symptoms of acid reflux.Unfortunately... this has not eradicated reflux disease. It has just changed its nature. While heartburn, ulceration and strictures have become rare, reflux-induced adenocarcinoma of the esophagus is becoming increasingly common. Adenocarcinoma of the esophagus and gastric cardia is now the most rapidly increasing cancer type in the Western world.At present, there is no histologic test that has any practical value in the diagnosis of reflux disease. The only histologic diagnostic criteria are related to changes in the squamous epithelium which are too insensitive and nonspecific for effective patient management. It is widely recognized that columnar metaplasia of the esophagus (manifest histologically as cardiac, oxyntocardiac and intestinal epithelia) is caused by reflux. However, except for intestinal metaplasia, which is diagnostic for Barrett esophagus, these columnar epithelia are not used to diagnose reflux disease in biopsies. The reason for this is that these epithelial types are indistinguishable from "normal" "gastric" cardiac mucosa. In standard histology texts, this "normal gastric cardia" is 2-3 cm long.In the mid-1990s, Dr. Chandrasoma and his team at USC produced autopsy data suggesting that cardiac and oxyntocardiac mucosa is normally absent from this region and that their presence in biopsies was histologic evidence of reflux disease. From this data, they determined that the presence of cardiac mucosa was a pathologic entity caused by reflux and could therefore be used as a highly specific and sensitive diagnostic criterion for the histologic diagnosis of reflux disease. They call this entity "reflux carditis". In addition, the length of these metaplastic columnar epithelia in the esophagus was an accurate measure of the severity of reflux disease in a given patient.At present, there is some controversy over whether cardiac mucosa is totally absent or present normally to the extent of 0-4 mm. While this should not be a deterrent to changing criteria which are dependent on there normally being 20-30 cm of cardiac mucosa, there has been little mainstream attempt to change existing endoscopic and pathologic diagnostic criteria in the mainstream of either gastroenterology or pathology. The ATLAS will be the source of easily digestible practical information for pathologists faced with biopsies from this region. It will also guide gastroenterologists as they biopsy these patients.

    • Drugs During Pregnancy and Lactation

      • 2nd Edition
      • June 8, 2007
      • Christof Schaefer + 2 more
      • English
      • eBook
        9 7 8 0 0 8 0 5 4 9 7 7 4
      The latest edition is the resource for any practicing OB/GYN, family physician, midwife, or pharmacist who prescribes medicinal products to or evaluates environmental or occupational exposures in women who are or may become pregnant. Based on the highly successful seven German editions of this reference, the up-to-date drug listings have been revised into a handy pocket guide color tabbed for quick access to important information. Easy to reference each drug is listed discussing the side effects, general impact on organ systems, potential toxicity, and risks before offering dosage recommendations. It is the only book of its kind to provide conclusive information on treatments for diseases during pregnancy and lactation and actions to be taken after (inadvertant) exposure to drugs suspected to be developmentaly toxic. Unlike other dosage guides, this edition is an affordable, compact compendium of knowledge on the very latest drugs and their effects on pregnant/lactating women.

    • Side Effects of Drugs Annual

      • 1st Edition
      • Volume 29
      • May 9, 2007
      • Jeffrey K. Aronson
      • English
      • Hardback
        9 7 8 0 4 4 4 5 1 9 8 6 3
      • eBook
        9 7 8 0 0 8 0 5 2 2 8 1 4
      The Side Effects of Drugs Annual was first published in 1977. It has been continually published since then, as a yearly update to the voluminous encyclopedia Meyler's Side Effects of Drugs. Each new Annual continues to provide clinicians and medical investigators with a reliable and critical yearly survey of new data and trends in the area of Adverse Drug Reactions and Interactions. An international team of specialists has contributed to the Annuals by selecting critically from each year's writing all that is truly new and informative, by critically interpreting it, and by pointing to whatever is misleading.

    • Elsevier's Dictionary of Vitamins and Pharmacochemistry

      • 1st Edition
      • December 4, 2006
      • Henry Philippsborn
      • English
      • Hardback
        9 7 8 0 4 4 4 5 1 6 6 0 2
      • eBook
        9 7 8 0 0 8 0 4 8 8 7 9 0
      The dictionary will contain terms covering the following fields and subfields: Vitamin Technology: Vitamin biochemistry / Physiology; Origin of vitamins: natural, synthetic; Fat-soluble vitamins; Water-soluble vitamins; Vitamins as antioxidants; Vitamin deficiencies / Hypervitaminosis - Enzymes/Proteins: Biotechnology as applied biological science aimed at industrial exploitation - Hormones: Biochemistry; Physiology - Pharmaceutical Chemistry / Pharmaceutical Technology / Pharmaceutical Processes: Conception of the active principles; Structural analysis; Antibiotics and their way of action; Biochemistry; The Drug / The Medicament: Definition, origin, way of action; Biochemistry - Medical Aspects in the languages English, German, French and Portuguese.

    • Pharmaceutical Manufacturing Encyclopedia

      • 3rd Edition
      • December 1, 2006
      • William Andrew William Andrew Publishing
      • English
      • eBook
        9 7 8 0 8 1 5 5 1 8 5 6 3
      • eBook
        9 7 8 0 0 8 0 9 4 7 2 6 6
      This industry standard encyclopedia on pharmaceutical manufacturing processes has been completely updated to include FDA drugs approved up to the summer of 2004. The encyclopedia gives details for the manufacture of 2226 pharmaceuticals that are being marketed as a trade-named product somewhere in the world. Each entry includes:ò Therapeutic function ò Chemical and common nameò Structural Formulaò Chemical Abstracts Registry no.ò Trade name, manufacturer, country, and year introducedò Raw Materialsò Manufacturing ProcessIn addition, references are also cited under each drug's entry to major pharmaceutical works where additional information can be obtained on synthesis and the pharmacology of the individual products.

    • GABA

      • 1st Edition
      • Volume 54
      • July 26, 2006
      • English
      • Paperback
        9 7 8 0 1 2 4 1 1 1 5 0 9
      • eBook
        9 7 8 0 0 8 0 4 6 4 7 3 2
      A great deal of progress has been made in defining GABA (gamma-aminobutyric acid) transmission in the brain. Volume 54 of the Advances in Pharmacology series has also provided new insights into fundamental features of neurotransmission in general, such as the importance of allosterism and coincident signaling in regulating receptor function and overall cellular activity. These studies have led to the design and development of new drugs and potential therapeutic agents. Given the successes achieved over the first 50 years of GABA research, it is certain the 6th decade will yield its share of surprising discoveries and new insights. Published in this volume are articles providing thoughts and perspectives on this topic, some with the benefit of hindsight, others in the context of recent findings, but all with a hint, or prediction, of what the future holds as the secrets of GABA neurotransmission continue to unfold.Advances in Pharmacology is available online on ScienceDirect — full-text online of volumes 48 onwards.

    • Pharmacy Law and Practice

      • 4th Edition
      • July 10, 2006
      • Jon Merrills + 1 more
      • English
      • Paperback
        9 7 8 0 4 4 4 5 2 2 0 1 6
      • eBook
        9 7 8 0 0 8 0 4 7 9 9 6 5
      Suitable for both students and practicing pharmacists, the latest edition of this classic textbook provides comprehensive coverage of an essential component of the U.K. pharmacy curriculum: pharmacy law and ethics. Completely rewritten since the last edition to reflect the rapid pace at which this field moves, it offers a clear, readable and non-technical guide on balancing the needs of patients with the letter of the law. It explains what happens and why in a reader-friendly format, taking a problem solving approach, and even provides an introduction to pharmacy issues for solicitors and legal personnel. Any pharmacist, student, or regulatory authority will find it appropriate for either a serious study or for answering questions which occur in practice.

    • Chondroitin Sulfate

      • 1st Edition
      • Volume 53
      • June 28, 2006
      • English
      • eBook
        9 7 8 0 0 8 0 4 7 1 9 5 2
      CS is an unbranched, polydisperse, complex glycosaminoglycan extracted and purified from various tissues. This polyanion is interacting with both plasma and cells, it is able to modulate many biochemical and physiologic processes. Due to the presence of sulfate groups in different amounts and located in various positions, CS represents a very heterogeneous family of polysaccharides. therefore, the preparative approach and the analytical techniques are of paramount importance to produce CS with specific structure and properties and of pharmaceutical grade.

    • Physiology of the Gastrointestinal Tract

      • 4th Edition
      • May 10, 2006
      • Leonard R. Johnson + 5 more
      • English
      • eBook
        9 7 8 0 0 8 0 4 5 6 1 5 7
      FROM THE PREFACE:The original purpose of the First Edition of Physiology of the Gastrointestinal Tract—to collect in one set of volumes the most current and comprehensive knowledge in our field—was also the driving force for the Fourth Edition. The explosion of information at the cellular level, made possible in part by the continued emergence of powerful molecular and cellular techniques, has resulted in a greater degree of revision than that of any other edition. The first section, now titled "Basic Cell Physiology and Growth of the Gl Tract" contains numerous new chapters on topics such as transcriptional regulation, signaling networks in development, apoptosis, and mechanisms in malignancies. Most of the chapters in this section were edited by Juanita L. Merchant. Section II has been renamed "Neural Gastroenterology and Motility" and has been expanded from seven chapters with rather classic titles to more than twenty chapters encompassing not only the movement of the various parts of the digestive tract but also cell physiology, neural regulation, stress, and the regulation of food intake. Almost all of the chapters were recruited and edited by Jackie D. Wood. The third section is entirely new and contains chapters on "Immunology and Inflammation" which were edited by Kim E. Barrett. The fourth section on the "Physiology of Secretion" consists of chapters with familiar titles, but with completely updated information to reflect the advances in our understanding of the cellular processes involved in secretion. The last section on "Digestion and Absorption" contains new chapters on the intestinal barrier, protein sorting and ion channels along with those focusing on the uptake of specific nutrients. These chapters were recruited and edited by Hamid M. Said and Fayez K. Ghishan.

    • Annual Reports in Medicinal Chemistry

      • 1st Edition
      • Volume 40
      • December 19, 2005
      • Annette M. Doherty
      • English
      • Paperback
        9 7 8 0 1 2 0 4 0 5 4 0 4
      • eBook
        9 7 8 0 0 8 0 4 5 8 1 7 5
      Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies. Sections I-IV are disease orientated and generally report on specific medicinal agents. Sections V and VI continue to emphasize important topics in medicinal chemistry, biology, and drug design. Section VII looks at Trends and Perspectives in the pharmaceuticals market.

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