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Elsevier

Books in Pharmacology

Elsevier's Pharmacology collection studies how drugs interact with biological systems to improve health and treat disease. It covers pharmacodynamics, exploring drug effects on biology, and pharmacokinetics, studying how the body affects drugs. Branches like Pharmacogenetics. Essential for pharmacologists, this collection offers invaluable insights into drug interactions, efficacy, and safety, crucial for advancing drug development and improving patient outcomes.

  • Lo esencial en farmacología. Cursos Crash

    • 6th Edition
    • Catrin Page
    • Spanish
    Con una fórmula que ha demostrado su éxito a lo largo de los últimos 25 años, cada volumen de la serie se ha actualizado por completo para facilitar el estudio. La serie está escrita por estudiantes de últimos cursos y recién graduados que acaban de superar sus exámenes, y toda la información ha sido cuidadosamente revisada por profesores universitarios. Este volumen de la serie se ha mejorado para satisfacer las necesidades de los estudiantes de Medicina actuales, y las de los estudiantes y profesionales de otras disciplinas sanitarias que requieran un acceso rápido a los aspectos esenciales de la farmacología. Cada capítulo guía de forma sucinta por todos los temas curriculares, integrando los aspectos clínicos con la ciencia básica relevante y evitando los detalles innecesarios o confusos. Los cuadros destacados a lo largo del texto ofrecen los apuntes, las sugerencias y los puntos clave esenciales. Se incluye una sección de autoevaluación totalmente revisada y adaptada a los últimos formatos de exámenes para comprobar los conocimientos y para ayudar en la preparación de las pruebas. Completamente revisada y actualizada, esta sexta edición ofrece un recurso accesible de aprendizaje y repaso que facilite la compresión de los principios y las aplicaciones de la farmacología en todas las áreas de la medicina y la cirugía. Comienza con un capítulo introductorio sobre los principios básicos de la farmacología. En el resto de los capítulos, se describen los efectos de los fármacos en los distintos sistemas orgánicos y se incluyen actualizaciones sobre los avances farmacológicos más recientes en medicina (p. ej., las nuevas terapias dirigidas en oncología y enfermedades inflamatorias, así como los nuevos tratamientos utilizados en el manejo de la diabetes y la insuficiencia cardíaca). La sección de autoevaluación se ha actualizado para reflejar el contenido y el estilo de varios exámenes de pre- y posgrado. Las preguntas de autoevaluación se centran en la farmacología clínica y su aplicación a casos reales de la práctica clínica.

  • Capsaicin, the Pungent Principle in Hot Pepper

    From Basic Pharmacology to Therapeutic Applications
    • 1st Edition
    • Arpad Szallasi
    • English
    Capsaicin, the Pungent Principle in Hot Pepper: From Basic Pharmacology to Therapeutic Applications explores capsaicin's biological and pharmacological characteristics, from its discovery and isolation to its receptor identification and antagonists. The book's structure is divided into three sections, starting with the historical development of research on capsaicin. This foundational section provides a thorough understanding of the compound's journey from a simple pungent ingredient to a significant element in pharmacological studies. The second part of the book delves into capsaicin’s biological effects and pharmacology, covering areas such as nociception, pain, salivary secretion, body temperature regulation, and blood pressure regulation.Finally, the book examines the clinical applications of capsaicin, discussing potential future developments in desensitization, pain relief, injections, effects on the tumor microenvironment, appetite control, and longevity. This book is invaluable for pharmacology researchers and clinicians in pain management and cancer, offering insights into the unique characteristics and therapeutic potential of capsaicin.

  • Fundamentals of Biologicals Regulation

    Vaccines and Biotechnology Medicines
    • 2nd Edition
    • Rebecca Sheets + 6 more
    • English
    This second edition of Fundamentals of Biologicals Regulation: Vaccines and Biotechnology Medicines serves as an introduction to the international regulatory arena in which biologicals are developed and offers an overview of the processes and insight into the scientific concepts underpinning global regulations. In this new edition the book provides more in-depth coverage of Quality by Design, Combination Products, Quality Target Product Profiles, Risk Management Plans and REMS, and switching from reliance on in vivo to in vitro analytical methods. This new edition also reflects the new developments and processes accelerated by the COVID-19 vaccine experience, including emergency use authorizations and conditional marking authorizations. New pedagogic elements and case studies have been added to improve learning outcomes for students. This book provides multiple levels of readership with guidance on basic concepts, a detailed look at regulatory challenges, and practical insight into how regulators consider regulatory science and regulatory process issues across various regions with emphasis on the European Medicines Agency and the U.S. Food and Drug Administration. Graduate students will benefit from the new pedagogic features. Regulatory professionals will have in Fundamentals of Biologicals Regulation: Vaccines and Biotechnology Medicines a complete guide to navigate through the approval process.

  • Brain Shuttle Peptides: Development and Applications

    • 1st Edition
    • Volume 105
    • English
    Advances in Pharmacology, Volume 105, a new volume in this ongoing series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Introduction to brain shuttle peptides, In silico optimization of brain shuttle properties for passive diffusion, Shuttles derived from natural proteins, Shuttles derived from phage display, Chemically enhanced brain shuttle peptides, Brain delivery of gold nanoparticles, Brain delivery of lipid nanoparticles, Brain delivery of therapeutic proteins, In vitro BBB models for the study of brain shuttle transport, Physiological strategies for delivery across the BBB, and Polymeric Nanoparticles.

  • Emerging Trends in Cancer Pharmacology

    From Molecular Targets to Personalized Medicine
    • 1st Edition
    • Tapan Behl + 4 more
    • English
    Emerging Trends in Cancer Pharmacology: From Molecular Targets to Personalized Medicine gives readers a comprehensive and up-to-date resource on the latest developments and trends in the field of cancer pharmacology. It serves as a valuable reference for researchers, scientists, clinicians, and other professionals involved in cancer research, pharmacology, oncology, and personalized medicine. In recent years, there have been significant breakthroughs in understanding the molecular mechanisms of cancer and the development of targeted therapies. Additionally, personalized medicine has emerged as a promising approach to tailor treatments based on an individual's genetic profile, tumor characteristics, and other factors. These developments have the potential to revolutionize cancer treatment and improve patient outcomes. This book covers such developments.

  • Medicinal Plants

    Chemistry, Biology and Omics
    • 2nd Edition
    • Da-Cheng Hao + 1 more
    • English
    Medicinal Plants: Chemistry, Biology, and Omics, Second Edition is a reference to help researchers identify and master the patterns in the distribution of medicinal compounds on the phylogenetic tree to explore new drug resources and develop novel therapies against different diseases. The book provides a deeper understanding of how the interrelationship between phytometabolites, bioactivities and omics techniques facilitates sustainable conservation and application of phytomedicine resources. Now in 2nd edition, the contents have been updated to include topics as machine learning applications, geographic distribution of phytometabolites, comparative analysis of alkaloids, expanded coverage of selected taxa, and conditions like cardiovascular disease and cancer. The book is structured around chemotaxonomy. After an introduction and review of taxonomy, chemistry, biology and omics, the authors dive into a taxon-guided exploration of medicinal resources for Fritillaria, Chelidoniae, Dichocarpum, Aconitum, Cimicifugeae, Clematis, Potentilla, Rubus, Cannabis, and other taxa. All chapters follow a similar and consistent structure, offering detailed information on each of them. Researchers in phytopharmacology can acquire in-depth understanding of the interrelationships between chemistry, biology and omics, as well as the implications of the link between phylogeny, phytometabolites and bioactivities in medical biotechnology and sustainability. Clinicians can better understand the principles of mutual interactions between phytometabolites and drug efficacy.

  • Drug Metabolism in Diseases

    Leveraging Drug Metabolism and Disposition in Precision Medicine and Therapeutic Development
    • 2nd Edition
    • Wen Xie
    • English
    Drug Metabolism in Diseases: Leveraging Drug Metabolism and Disposition in Precision Medicine and Therapeutic Development, Second Edition provides essential knowledge for pharmaceutical scientists and biologists to understand the interplay between diseases and physiological conditions, impacting drug metabolism and its implications in personalized treatment. Expanded with six new chapters since the first edition, this updated book covers the latest scientific findings. Other important points include the book’s comprehensive reference on mutual effects between drug metabolism and diseases, implications in precision medicine, and therapeutic development. Pharmaceutical scientists, drug metabolism researchers, and research physicians will benefit from the expert insights provided.

  • Machine Learning in Drug Development: Part 2

    • 1st Edition
    • Volume 65
    • English
    Machine Learning in Drug Development: Part Two, Volume 65 in the Annual Reports on Medicinal Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Chapters in this volume explore Transforming Modern Drug Discovery with Machine Learning – Applications in Ligand-based Drug Design, Optimizing Multi-Modal Drug Design Through Computational Pocket Mapping and Data Integration, Harnessing AI for Nucleic Acid Drug Discovery: Small Molecule Targeting DNA and RNA, AI-aided Drug Development for Protein Degraders: Design, Lead Identification, and Optimization, and more.Additional section delve into Artificial Intelligence in the Development of Antiviral Drugs – Progress and Applications, Artificial Intelligence for Drug Target Identification, and Machine Learning in Proteomic Biomarker Discovery

  • Progress in Medicinal Chemistry

    • 1st Edition
    • Volume 64
    • English
    Progress in Medicinal Chemistry, Volume 64 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

  • Machine Learning in Drug Development: Part 1

    • 1st Edition
    • Volume 64
    • English
    Machine Learning in Drug Development: Part One, Volume 64 in the Annual Reports on Medicinal Chemistry series, highlights new advances in the field. Chapters in this release include Artificial Intelligence in Small Molecule and Nucleic Acid Research: A Review, AI-aided Drug Development for Protein Degraders: Design, Lead Identification, and Optimization, AI-aided Drug Development for Protein Degraders: Biology Validation, Disease-association, Drug Repurposing, Transforming Modern Drug Discovery with Machine Learning, Artificial Intelligence in the Development of Antiviral Drugs: Progress and Applications, Artificial Intelligence for Drug Target Identification, and Machine Learning in Proteomic Biomarker Discovery.

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