Books in Pharmacology

11-20 of 813 results in All results

Acute Toxicology Testing

2nd Edition
Shayne C. Gad + 1 more
Shayne C. Gad and Christopher P. Chengelis
October 13, 1997

eBook
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Acute toxicology testing provides the first line of defense against potentially dangerous chemicals. This book is a complete and practical guide to conducting and interpreting all regulatory required and commonly used acute toxicity tests. It presents detailed protocols for all of the common test designs and reviews their development and objectives. Acute Toxicology Testing, Second Edition will interest not only workers in the pharmaceutical industry, but also researchers and students in toxicology and public health.

Adenosine Receptors and Parkinson's Disease

1st Edition
Hiroshi Kase, Peter J. Richardson + 1 more
Hiroshi Kase, Peter J. Richardson and Peter Jenner
October 15, 1999

eBook
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This book is the first definitive overview on adenosine receptor antagonists and their application to the treatment of Parkinson's Disease. The effect of these novel non-dopamine drugs on vitro and in vivo systems clearly shows their potential for the treatment of this debilitating disease. This book covers how the Parkinson's disease antagonist drug, A2A, has been researched, developed, and tested. It is an essential book for researchers interested in the basal ganglia, purine biology, and Parkinson's Disease.

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Adenosine in the Nervous System

1st Edition
Richard E. Stone
Richard E. Stone
October 28, 1991

eBook
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This volume in a series on neuroscience provides an overview of the last 20 years of research into the biochemistry, physiology,pharmacology and clinical therapeutic potential of adenosine and its analogues in the nervous system. Among the topics covered are adenosine transport in nervous systemtissues, adenosine production and metabolism and the electropharmacology of adenosine.

Advanced Drug Delivery Systems for Colonic Disorders

1st Edition
Harish Dureja, Raimar Loebenberg + 3 more
Harish Dureja, Raimar Loebenberg, Sachin Kumar Singh + 2 more
November 4, 2023

Paperback
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eBook
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Advanced Drug Delivery Systems for Colonic Disorders presents state-of-the-art methods for targeted drug delivery to the colon. These methods can prolong drug half-lives, improve bioavailability, optimize pharmacokinetics, and reduce medication dosing frequency. Chapters allow readers to not only become familiar with advancements, but also understand concepts by providing illustrations, figures, and informative tables. Contents cover an overview of colonic diseases, the cellular and molecular mechanisms involved, current and traditional therapeutic approaches, biomaterials, oral drug delivery methods, targeted drug delivery, nutraceuticals and herbal medicine approaches, prebiotics, probiotics and symbiotics, nanomedicine approaches, and the status of clinical trials.This book is the perfect resources for researchers in pharma, biomaterials, and nutrition to help familiarize them with new and upcoming therapeutic methods. Research physicians in GI can also benefit from reading this book for its clinical applications.

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Advanced Issue Resolution in Safety Pharmacology

1st Edition
Mary Jeanne Kallman + 1 more
Mary Jeanne Kallman and Michael Pugsley
September 5, 2018

Hardback
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eBook
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Advanced Issue Resolution in Safety Pharmacology not only discusses unique issues that may emerge during the development of new medicines, but also provides detailed insights on how to resolve them. The book employs a valuable strategy that integrates preclinical findings with the clinical resolution of those findings. In addition, it introduces key interdisciplinary topics in an accessible and systematic format. Edited and written by leaders in the field of safety pharmacology, this book considerably advances the discussion on issue resolution topics, thus raising them to the next level of importance by providing scientists with an indispensable resource on solving safety issues.

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Advanced Scientific Computing in BASIC with Applications in Chemistry, Biology and Pharmacology

1st Edition
P Valko + 1 more
P Valko and S. Vajda
January 1, 1989

eBook
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This book gives a practical introduction to numerical methods and presents BASIC subroutines for real-life computations in the areas of chemistry, biology, and pharmacology. The choice of BASIC as the programming language is motivated by its simplicity, its availability on all personal computers and by its power in data acquisition. While most of the scientific packages currently available in BASIC date back to the period of limited memory and speed, the subroutines presented here can handle a broad range of realistic problems with the power and sophistication needed by professionals and with simple, step-by-step instructions for students and beginners.Please note that a diskette containing the 37 program modules and 39 sample programs listed in the book is no longer available.The main task considered in the book is that of extracting useful information from measurements via modelling, simulation, and statistical data evaluations. Efficient and robust numerical methods have been chosen to solve related problems in numerical algebra, nonlinear equations and optimization, parameter estimation, signal processing, and differential equations. For each class of routines an introduction to the relevant theory and techniques is given, so that the reader will recognise and use the appropriate method for solving his or her particular problem. Simple examples illustrate the use and applicability of each method.

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Advancement of Phenolic Acids in Drug Discovery

1st Edition
Naresh Kumar, Nidhi Goel + 1 more
Naresh Kumar, Nidhi Goel and Jesus Simal Gandara
April 1, 2024

Paperback
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eBook
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Advancement of Phenolic Acids in Drug Discovery: Fundamental and Applications offers comprehensive coverage of the ADMET profiles of phenolic acids, their extraction method and prospects for drug design and development. Chapters overview phenolic acids and their characterization, discuss the role of phenolic acids in plant systems, present sources and detailed extraction methods of phenolic acids, and cover phenolic acid mechanisms of action as it relates to several key diseases and health conditions, including their role as antioxidant agents, anti-inflammatory and analgesic drugs, anti-microbial drugs, anti-viral drugs, anti-cancer drugs, diabetes and metabolic dysfunctions, neurological disorders, cardiovascular diseases. The book’s final chapters cover nanoscience aspects of phenolic acids, biomedical applications, and concludes with challenges and opportunities presented by phenolic acids. This is the ideal reference for researchers in the fields of drug development, both in academia and corporate settings. Researchers of related areas like food science and medicinal chemistry will also benefit from this in-depth profiling of therapeutical properties of phenolic acids.

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Advances in Cancer Research

1st Edition
George F. Vande Woude + 1 more
George F. Vande Woude and George Klein
October 20, 1997

Hardback
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eBook
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Academic Press proudly presents this Cumulative Subject Index covering Volumes 50-72 of Advances in Cancer Research. In one comprehensive source, the interested reader can find references to specific articles on topics such as breast cancer, prostate cancer, Kaposi's sarcoma, Burkitt's lymphoma, leukemias, oncogenes, transcription factors, tumor genetics, p53, T-cell receptors, and drug resistance. This cumulative index will serve not only as a complete overview of the major topics published in Advances in Cancer Research, but also as an indicator of the progress made in cancer research over the last ten years.

Advances in Cancer Research

1st Edition
George F. Vande Woude + 1 more
George F. Vande Woude and George Klein
March 31, 1998

Hardback
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eBook
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This volume of Advances in Cancer Research begins with a review by M. Roussel of the key effectors of cytokine and growth factor signaling to the cell cycle block. P 53 and how it controls the cell cycle, genomic stability, and apoptosis are reviewed by M.R.A. Mowat. The third chapter, by T.S. Lewis and colleagues, discusses the effect of MAP kinase cascades as examples of signal transduction mechanisms in signaling pathways. In Chapter 4, Sozi et al. Review the frequent abnormalities found in the FHIT gene in a variety of cancer-derived cell lines. Volume 74 concludes with an overview by J.J. Hsuan and co-workers of the cellular functions of PtdlnsP2 and the regulation of its biosynthesis.

Advances in Cancer Research

1st Edition
Kenneth D. Tew + 1 more
Kenneth D. Tew and Paul B. Fisher
June 18, 2015

Hardback
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eBook
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Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics, including taxane-anti-androgens cross-resistance in advanced prostate cancer and proteasome inhibitors in the treatment of multiple myeloma.