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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

BooksJournals

    • Advances in Cancer Research

      • 1st Edition
      • Volume 84
      • February 22, 2002
      • English
      • Hardback
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      • eBook
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      The Advances in Cancer Research series provides invaluable information on the exciting and fast-moving field of cancer research. This volume presents outstanding and original reviews on a variety of topics, including gene expression in inherited breast cancer, multiparameter analyses of cell cycle regulation in tumorigenesis, Rho GTPases in transformation and metastasis, the myc oncogene, genetic requirements for the episomal maintenance of oncogenic herpesvirus genomes, treatment of Epstein-Barr virus-associated malignancies with specific T cells, the role of glycogen synthase kinase-3 in cancer, chronic immune activation and inflammation in the pathogenesis of AIDS and cancer, and molecular biology of Hodgkin's lymphoma.

    • Gene Therapy Methods

      • 1st Edition
      • Volume 346
      • February 22, 2002
      • English
      • Hardback
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      • eBook
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      This volume in the prestigious Methods in Enzymology series discusses methods currently used in preclinical and clinical gene therapy. Subjects covered in this book, such as the use of adeno-associated virus delivery for treatment of Parkinson's disease, are topical and are presented in the methods-oriented style popularized by this series.

    • Protein Sensors and Reactive Oxygen Species, Part B: Thiol Enzymes and Proteins

      • 1st Edition
      • Volume 348
      • February 22, 2002
      • English
      • Paperback
        9 7 8 0 1 2 3 9 1 7 9 7 3
      • Hardback
        9 7 8 0 1 2 1 8 2 2 5 1 4
      • eBook
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      This volume of Methods in Enzymology is a companion to Volume 347 and addresses direct sensing of reactive oxygen species and related free radicals by thiol enzymes and proteins.

    • Cellular and Molecular Toxicology

      • 1st Edition
      • February 14, 2002
      • J.P. Vanden Heuvel + 3 more
      • English
      • Hardback
        9 7 8 0 4 4 4 5 0 8 6 8 3
      Volume 14 in the series Comprehensive Toxicology extends and complements the previously published 13-volume set. This volume will be available separately.Toxicolog... is the study of the nature and actions of chemicals on biological systems. In more primitive times, it really was the study of poisons. However, in the early 1500s, it was apparent to Paracelsus that "the dose differentiates a poison and a remedy". Clearly, the two most important tenets of toxicology were established during that time. The level of exposure (dose) and the duration of exposure (time) will determine the degree and nature of a toxicological response.Since that time the discipline of toxicology has made major advances in identifying and characterizing toxicants. The growth of toxicology as a scientific discipline has been driven to a large extent by the use of extremely powerful molecular and cell biology techniques. The overall aim of this volume is to demonstrate how these advances are being used to elucidate causal pathways (or linkages) for potential adverse health consequences of human exposure to environmental chemicals or radiation.A unique feature of this volume is its illustration of how carefully-designed studies of the molecular mechanisms of chemical action provide not only understanding of the potential toxicity of the chemical under investigation, but also new insights into the functioning of the biological system used as an experimental model. Each chapter contains a listing of major peer-reviewed articles and reviews and useful web-sites. In addition, each chapter contains a broad introductory section that outlines the subsequent sections. These Introductory and Overview sections are designed to be stand alone chapters, and may be packaged as a textbook in graduate level courses.

    • Protein Folding in the Cell

      • 1st Edition
      • Volume 59
      • February 14, 2002
      • English
      • eBook
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      This volume of Advances in Protein Chemistry provides a broad, yet deep look at the cellular components that assist protein folding in the cell. This area of research is relatively new--10 years ago these components were barely recognized, so this book is a particularly timely compilation of current information. Topics covered include a review of the structure and mechanism of the major chaperone components, prion formation in yeast, and the use of microarrays in studying stress response. Outlines preceding each chapter allow the reader to quickly access the subjects of greatest interest. The information presented in this book should appeal to biochemists, cell biologists, and structural biologists.

    • Stem Cells and Cell Signalling in Skeletal Myogenesis

      • 1st Edition
      • Volume 11
      • February 8, 2002
      • D.A. Sassoon
      • English
      • Paperback
        9 7 8 0 4 4 4 5 5 4 2 4 6
      • eBook
        9 7 8 0 0 8 0 5 6 9 7 3 4
      Skeletal muscle development is perhaps one of the best understood processes at the molecular, cellular and organismal level due in large part to the fact that primary myogenic cells (myoblasts) will grow and subsequently differentiate into myotubes in culture. With the advent of reverse mouse genetics, many of the observations gained through the study of myogenic cells in vitro have been directly tested in vivo. What has emerged is a complex but cohesive story of how myogenic cells are initially specified in the vertebrate embryo and how muscle fibers ultimately achieve their respective identities (i.e. fast versus slow) to perform their function. This collection of chapters is focused on these developments. The book discusses old and new directions for the skeletal muscle field and points out directions where the field may eventually progress.

    • International Review of Cytology

      • 1st Edition
      • Volume 213
      • January 29, 2002
      • English
      • Hardback
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      • eBook
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      International Review of Cytology presents current advances and comprehensive reviews in cell biology--both plant and animal. Articles in this volume address topics such as GABA and GABA receptors in CNS and other organs, neuroendocrine control of pheromone biosynthesis in moths, gene transfer to salivary glands, cell type-specificexpress... of secretory TFF-peptides in the brain, molecular patterning along the sea urchin animal-vegetal axis, and cell and molecular cell biology of melanin-concentratin... hormone. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research.

    • Principles and Practice of Clinical Research

      • 1st Edition
      • January 24, 2002
      • John I. Gallin
      • English
      • eBook
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      Principles and Practice of Clinical Research is a comprehensive text which addresses the theoretical and practical issues involved in conducting clinical research. This book is divided into three parts: ethical, regulatory, and legal issues; biostatistics and epidemiology; technology transfer, protocol development and funding. It is designed to fill a void in clinical research education and provides the necessary fundamentals for clinical investigators. It should be of particular benefit to all individuals engaged in clinical research, whether as physician or dental investigators, Ph.D. basic scientists, or members of the allied health professions, as well as both students and those actively participating in clinical research.

    • Trends in High Pressure Bioscience and Biotechnology

      • 1st Edition
      • Volume 19
      • January 21, 2002
      • R. Hayashi
      • English
      • eBook
        9 7 8 0 0 8 0 5 4 3 2 2 2
      A world wide interest in the various aspects of high pressure in the field of biological science led to the First International Conference on High Pressure Bioscience and Biotechnology in Kyoto, Japan. High pressure bioscience encompasses the fields of food sciences, pharmacy and medical fields and some high pressure techniques are used in the production of industrial products. Moreover, high pressure is a valuable tool for the study of natural macromolecules including biomembranes which are composed, primarily, of lipid and protein. Many intermediate processes in the pressure-induced protein unfolding have been discovered, as a result. This book covers the entire range of current high pressure bioscience and its possible applications.

    • Principles of Bone Biology

      • 2nd Edition
      • January 19, 2002
      • John P. Bilezikian + 2 more
      • English
      • eBook
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      Principles of Bone Biology is the essential resource for anyone involved in the study of bones. It is the most comprehensive, complete, up-to-date source of information on all aspects of bones and bone biology in one convenient source. Written and published in less than one year, it will become an indispensable resource for any scientific or medical library. This, second edition, details countless advances over the past five years, both by updating old chapters and providing additional material. It takes the reader from the basic elements of fundamental research to the most sophisticated concepts in therapeutics.

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