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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

    • Protein Phosphorylation in Aging and Age-Related Disease

      • 1st Edition
      • Volume 16
      • February 17, 2004
      • Paul Mark Mattson
      • English
      • Hardback
        9 7 8 0 4 4 4 5 1 5 8 3 4
      It can be argued that ATP is the most important molecule in cells. Not only is ATP the key energy source for cells, but it is also the source of phosphate groups that are transferred to a variety of substrate proteins via the action of elaborate families of protein kinases. An equally elaborate array of protein phosphatases can remove phosphate groups from proteins. It is now well established that protein phosphorylation is a widely used mechanism for cells to selectively modulate the function of a variety of proteins including enzymes, ion channels and pumps and structural proteins. In this volume of ACAG leading experts describe the evidence that protein phosphorylation is altered in aging and age-related disease. Protein phosphorylation controls fundamental processes such as transcription and translation, regulation of the cell cycle, signalling within and between cells, cell motility, synaptic function and so on. Recent findings are revealing how phosphorylation dependent signalling cascades may control lifespan with a prime example being the insulin-signalling pathway first described in c-elegans and now emerging as an important regulator of lifespan of mammals also. Many of the functional changes that occur during aging such as impaired learning and memory and altered energy metabolism are controlled by protein phosphorylation and it is, therefore, important to understand how mechanisms of protein phosphorylation may either mediate aging or provide adaptive responses that allow successful disease-free aging. The authors in addition to considering the roles of protein phosphorylation in aging describe the evidence that abnormalities in protein phosphorylation contribute to the pathogenesis of major age-related diseases including diabetes, atherosclerosis and neurodegenerative disorders such as Alzheimer's and Parkinson's diseases.
    • Chromatin and Chromatin Remodeling Enzymes, Part B

      • 1st Edition
      • Volume 376
      • February 11, 2004
      • Carl Wu + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 1 8 2 7 8 0 9
      • eBook
        9 7 8 0 0 8 0 4 9 7 1 4 3
      DNA in the nucleus of plant and animal cells is stored in the form of chromatin. Chromatin and the Chromatin remodelling enzymes play an important role in gene transcription.
    • Molecular Endocrinology

      • 3rd Edition
      • February 10, 2004
      • Franklyn F. Bolander
      • English
      • Paperback
        9 7 8 0 1 2 3 9 9 2 0 2 4
      • Hardback
        9 7 8 0 1 2 1 1 1 2 3 2 5
      • eBook
        9 7 8 0 0 8 0 4 9 7 3 3 4
      Molecular Endocrinology, Third Edition summarizes the area and provides an in-depth discussion of the molecular aspects of hormone action, including hormone-receptor interactions, second messenger generation, gene induction, and post-transcriptional control. Thoroughly revised and updated, the Third Edition includes new information on growth factors hematopoietic-immune factors, nonclassical hormones, receptors, transduction, transcriptional regulation, as well as other relevant topics. Incorporating an abundance of new information, this text retains the self-contained, focused, and easily readable style of the Second Edition.
    • Chromatin and Chromatin Remodeling Enzymes Part C

      • 1st Edition
      • Volume 377
      • January 30, 2004
      • Carl Wu + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 1 8 2 7 8 1 6
      • eBook
        9 7 8 0 0 8 0 4 9 7 1 5 0
      DNA in the nucleus of plant and animal cells is stored in the form of chromatin. Chromatin and the chromatin remodelling enzymes play an important role in gene transcription.
    • Chromatin and Chromatin Remodeling Enzymes, Part A

      • 1st Edition
      • Volume 375
      • January 23, 2004
      • Carl Wu + 1 more
      • English
      • eBook
        9 7 8 0 0 8 0 4 9 7 1 3 6
      DNA in the nucleus of plant and animal cells is stored in the form of chromatin. Chromatin and the Chromatin remodellng enzymes play an important role in gene transcription.
    • Elsevier's Dictionary of Abbreviations, Acronyms, Synonyms and Symbols used in Medicine

      • 1st Edition
      • January 20, 2004
      • S.A. Tsur
      • English
      • Hardback
        9 7 8 0 4 4 4 5 1 2 6 5 9
      • eBook
        9 7 8 0 0 8 0 9 3 0 2 4 4
      Over 10,000 abbreviations are added to this second edition of the dictionary, the first edition of which was published in 1999. The new edition contains over 30,000 abbreviations of terms used in the field of anatomy, bacteriology, biology, chemistry, medicine (human and veterinary), pathology, pharmacology, etc., with especially detailed itemization of the chemical elements, hormones, insulins, kidney function tests, pulmonary function tests, serological tests for syphilis, symbols used in various disciplines, such as biology, calculation, chemistry, Greek alphabet, medicine and pharmacy, numeration and signs of the zodiac, the vitamins.
    • The EGF Receptor Family

      • 1st Edition
      • December 19, 2003
      • Graham Carpenter
      • English
      • Paperback
        9 7 8 0 1 2 3 8 8 5 7 1 5
      • eBook
        9 7 8 0 0 8 0 4 7 2 5 8 4
      The enormity of the literature on growth factors, plus the breadth of the biological disciplines and technical expertise required prohibits a comprehensive review by even a multi-disciplinary panel of authors. To provide an alternative that is feasible for authors and digestible by readers, this review compendium consists of a collection of articles, each covering an aspect of teh ErbB/EGF field. This compilation features articles on growth factor ligands, neuregulins, and individual receptors. The second part of the book concentrates on the biological context of the ErbB receptors, particularly in mammary development and in cancer. It concludes with a discussion of the genetic systems that have enabled significant advances in research in this area.
    • International Review of Cytology

      • 1st Edition
      • Volume 232
      • December 18, 2003
      • Kwang W. Jeon
      • English
      • Hardback
        9 7 8 0 1 2 3 6 4 6 3 6 1
      • Paperback
        9 7 8 0 1 2 4 1 1 2 1 7 9
      • eBook
        9 7 8 0 0 8 0 4 9 5 6 1 3
      The acclaimed International Review of Cytology series presents current advances and reviews in cell biology, both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research.
    • The Ovary

      • 2nd Edition
      • December 18, 2003
      • Peter C.K. Leung + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 4 4 4 5 6 2 8
      • eBook
        9 7 8 0 0 8 0 5 4 2 5 8 4
      This second edition of The Ovary incorporates the dramatic research developments regarding the ovarian life cycle within the past decade. It looks at ovarian function from a detailed molecular and cellular level. The updated chapters, along with the new material, represent an unparalleled compilation of chapters relevant to contemporary ovarian physiology. The book is divided into 8 sections: The Ovarian Follicular Apparatus: Operational Characteristics; Oocyte Maturation and Ovulation; The Corpus Luteum; Putative Intraovarian Regulators; Cyclic Ovarian Cell Death; Novel Experimental Models; Human Ovarian Pathophysiology: Select Aspects; and Human Ovarian Surface Epithelium and Neoplasia.
    • Energy Coupling and Molecular Motors

      • 3rd Edition
      • Volume 23
      • December 18, 2003
      • Fuyuhiko Tamanoi + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 4 1 1 1 7 6 9
      • eBook
        9 7 8 0 0 8 0 5 2 1 5 1 0
      This volume examines a number of different molecular motors that utilize ATP. The molecular machines to be discussed include ATP synthase, myosin, kinesin, DNA helicases, DNA topoisomerases, chaperones and bacterial rotory motors. The discussion of these various molecular motors is rarely undertaken in one volume and will serve as a great resource for scientists studying structure and function of multiprotein complexes as well as those working on energy coupling mechanisms. The areas of research presented in this volume do not normally overlap, and yet they share common mechanisms.