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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

    • Liposomes, Part E

      • 1st Edition
      • Volume 391
      • February 10, 2005
      • English
      • Hardback
        9 7 8 0 1 2 1 8 2 7 9 6 0
      • eBook
        9 7 8 0 0 8 0 4 5 7 4 3 7
      Liposomes are cellular structures made up of lipid molecules. Important as a cellular model in the study of basic biology, liposomes are also used in clinical applications such as drug delivery and virus studies. Liposomes Part E is a continuation of previous Methods in Enzymology Liposome volumes A, B, C and D.
    • RNA Interference

      • 1st Edition
      • Volume 392
      • February 10, 2005
      • David R. Engelke + 1 more
      • English
      • eBook
        9 7 8 0 0 8 0 4 5 5 3 9 6
      The critically acclaimed laboratory standard, Methods in Enzymology, is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. The series contains much material still relevant today - truly an essential publication for researchers in all fields of life sciences.RNA Interference will cover RNAi in non-vertebrates (plants, C. elegans, drosophila, and S. pombe), and Mammalian systems (human and non-human cells). This volume discusses extensive methodology related to delivery methods high throughput strategies and prospects as a human therapy agent.
    • Lipid Oxidation

      • 2nd Edition
      • February 1, 2005
      • Edwin N. Frankel
      • English
      • Hardback
        9 7 8 0 9 5 3 1 9 4 9 8 8
      • eBook
        9 7 8 0 8 5 7 0 9 7 9 2 7
      In this second edition, Edwin Frankel has updated and extended his now well-known book Lipid oxidation which has come to be regarded as the standard work on the subject since the publication of the first edition seven years previously. His main objective is to develop the background necessary for a better understanding of what factors should be considered, and what methods and lipid systems should be employed, to achieve suitable evaluation and control of lipid oxidation in complex foods and biological systems. The oxidation of unsaturated fatty acids is one of the most fundamental reactions in lipid chemistry. When unsaturated lipids are exposed to air, the complex, volatile oxidation compounds that are formed cause rancidity. This decreases the quality of foods that contain natural lipid components as well as foods in which oils are used as ingredients. Furthermore, products of lipid oxidation have been implicated in many vital biological reactions, and evidence has accumulated to show that free radicals and reactive oxygen species participate in tissue injuries and in degenerative disease. Although there have been many significant advances in this challenging field, many important problems remain unsolved. This second edition of Lipid oxidation follows the example of the first edition in offering a summary of the many unsolved problems that need further research. The need to understand lipid oxidation is greater than ever with the increased interest in long-chain polyunsaturated fatty acids, the reformulation of oils to avoid hydrogenation and trans fatty acids, and the enormous attention given to natural phenolic antioxidants, including flavonoids and other phytochemicals.
    • Advances in Enzyme Regulation

      • 1st Edition
      • Volume 44
      • January 30, 2005
      • George Weber
      • English
      • Hardback
        9 7 8 0 0 8 0 4 4 4 1 4 7
      • eBook
        9 7 8 0 0 8 0 9 1 3 8 6 5
      A direct spinoff of the Advances in Enzyme Regulation journal this internationally acclaimed series reports progress at the cutting edge in the strategic area of regulation at the molecular level. In an integrated presentation of original papers, leading scientists, Nobel Prize winners and other outstanding experts from many countries review the best research produced each year and evaluate what is newest and what promises to be the most important in clinical and basic investigations. The volumes serve as guideposts and beacons for investigators in planning research and teaching students in basic and clinical fields of endeavour. These books advance the general front of studies on metabolic regulation and the understanding of the molecular biology of control of gene expression by hormones, drugs and growth factors in cancer cells and in clinical situations of diabetes, inborn errors of metabolism and neoplasia.
    • Vitamin D

      • 2nd Edition
      • January 25, 2005
      • David Feldman + 2 more
      • English
      • eBook
        9 7 8 0 0 8 0 5 4 3 6 4 2
      Vitamin D, a steroid hormone, has mainly been known for its effects on bone and osteoporosis. The current therapeutic practices expand into such markets as cancer research, pediatrics, nephrology, dermatology, immunology, and genetics. This second edition includes over 100 chapters covering everything from chemistry and metabolism to mechanisms of action, diagnosis and management, new analogs, and emerging therapies. This complete reference works is a must have resource for anyone working in endocrinology, osteology, bone biology, or cancer research.
    • Current Topics in Developmental Biology

      • 1st Edition
      • Volume 65
      • January 19, 2005
      • English
      • Paperback
        9 7 8 0 1 2 4 1 1 2 5 5 1
      • eBook
        9 7 8 0 0 8 0 4 5 7 8 3 3
      Current Topics in Developmental Biology provides a comprehensive survey of the major topics in the field of developmental biology. The volumes are valuable to researchers in animal and plant development, as well as to students and professionals who want an introduction to cellular and molecular mechanisms of development. The series has recently passed its 30-year mark, making it the longest-running forum for contemporary issues in developmental biology. This volume contains ten important contributions from leading minds in developmental biology.
    • Handbook of Immunohistochemistry and in Situ Hybridization of Human Carcinomas

      • 1st Edition
      • January 12, 2005
      • M. A. Hayat
      • English
      • Hardback
        9 7 8 0 1 2 3 3 3 9 4 2 3
      • eBook
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      Immunohistochemistry is the use of specific antibodies to stain particular molecular species in situ. This technique has allowed the identification of many more cell types than could be visualized by classical histology, particularly in the immune system and among the scattered hormone-secreting cells of the endocrine system, and has the potential to improve diagnosis, prognosis and therapeutic options of cancer. Handbook of Immunohistochemistry and in Situ Hybridization of Human Carcinomas discusses all aspects of immunohistochemistry and in situ hybridization technologies and the important role they play in reaching a cancer diagnosis. It provides step-by-step instructions on the methods of additional molecular technologies such as DNA microarrays, and microdissection, along with the benefits and limitations of each method. The topics of region-specific gene expression, its role in cancer development and the techniques that assist in the understanding of the molecular basis of disease are relevant and necessary in science today. This book is the second volume of three planned, individually-sold volumes on this topic. Like Volume 1, this book fully explains the principles and applications of modern techniques used in the field of molecular genetics. It will be of particular interest to pathologists and molecular pathologists conducting both academic and/or clinical research.
    • Cytometry: New Developments

      • 4th Edition
      • Volume 75
      • January 6, 2005
      • English
      • eBook
        9 7 8 0 0 8 0 4 9 6 6 0 3
      The chapters in CYTOMETRY MCB volumes, including this 4th Edition, provide comprehensive description of particular cytometric methods and review their applications. Some chapters also describe new instrumentation and provide fundamental information on use of new fluorescent probes and on data analysis. Although the term "edition" suggests the update of earlier volumes, in fact, nearly all chapters of the 4th Edition are devoted to new topics. The authors were invited to present not only technical protocols, such as available in other methodology books that specialize in the protocol format, but also to discuss the aspects of the methodology that generally are not included in the protocols. Many chapters, thus, present the theoretical foundations of the described methods, their applicability in experimental laboratory and clinical setting, common traps and pitfalls, problems with data interpretation, comparison with alternative assays, choice of the optimal assay, etc. Some chapters review applications of cytometry and complementary methodologies to particular biological problems or clinical tasks.
    • International Review of Cytology

      • 1st Edition
      • Volume 242
      • January 6, 2005
      • Kwang W. Jeon
      • English
      • Paperback
        9 7 8 0 1 2 4 1 1 2 5 9 9
      • eBook
        9 7 8 0 0 8 0 4 5 7 7 6 5
      International Review of Cytology presents current advances and comprehensive reviews in cell biology – both plant and animal. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. Articles in this volume address the pathophysiological dynamics of human ovarian surface epithelial cells in epithelial ovarian carcinogenesis; morphodynamics of the secretory pathway; aspects of collagen mineralization in hard tissue frmation; the hypoxia-inducible factor and tumor progression along the angiogenic pathway; multidrug resistance in yeast candida; intracellular coupling of interstitial cells of cajal in the digestive tract; and chromatin organization in the mammalian nucleus.
    • The Liver in Biology and Disease

      • 1st Edition
      • Volume 15
      • December 31, 2004
      • English
      • Paperback
        9 7 8 0 4 4 4 5 4 7 6 2 0
      • Hardback
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      • eBook
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      The Liver in Biology and Disease was conceived as a sequel in the series Principles of Medical Biology, whose general aim continues to be the integration of human biology and molecular cell biology into modern molecular medicine. It is a volume molded by the Information Revolution which few will deny has forced the teaching faculties in our medical schools to curtail and prune the teaching load and focus on fundamentals and principles. With this intention in mind, a volume of this nature takes into account the close dependence of progress in the medical sciences on bioinformatics (gene and protein analysis) or more precisely, computational biology and of course, the Internet. In general, it follows the pattern of its predecessors.