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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

    • Writing Clinical Research Protocols

      • 1st Edition
      • August 4, 2005
      • Evan DeRenzo + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 2 1 0 7 5 1 1
      • eBook
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      This highly engaging guide for clinical researchers provides a foundation for improving skills in the understanding of ethical requirements in the design and conduct of clinical research. Writing Clinical Research Protocols includes practical information on ethical principles in clinical research, designing appropriate research studies, writing consent and assent documents, getting protocols approved, special populations, confidentiality issues, and the reporting of adverse events. A valuable appendix includes a listing of web resources about research ethics as well as a glossary. This is an invaluable resource for basic scientists collaborating in clinical trials, physician investigators, clinical research fellows, research nurse coordinators, residents, and anyone who wants a better understanding of the clinical trials process.
    • Vitamins and Hormones

      • 1st Edition
      • Volume 71
      • August 2, 2005
      • Gerald Litwack
      • English
      • eBook
        9 7 8 0 0 8 0 4 5 9 7 8 3
      First published in 1943, VITAMINS AND HORMONES is the longest-running serial published by Academic Press. In the early days of the Serial, the subjects of vitamins and hormones were quite distinct. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms. Under the capable and qualified editorial leadership of Dr. Gerald Litwack, VITAMINS AND HORMONES continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists, and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and vitamins will, as always, turn to this series for comprehensive reviews by leading contributors to this and related disciplines.
    • Molecular Imaging

      • 1st Edition
      • August 1, 2005
      • Ammasi Periasamy + 1 more
      • English
      • Hardback
        9 7 8 0 1 9 5 1 7 7 2 0 6
      • eBook
        9 7 8 0 0 8 0 5 3 6 8 7 3
      The detection and measurement of the dynamic interactions of proteins within the living cell are critical to our understanding of cell physiology and pathophysiology. With FRET microscopy and spectroscopy techniques, basic and clinical scientists can make such measurements at very high spatial and temporal resolution. But sources of background information about these tools are very limited, so this book fills an important gap. It covers both the basic concepts and theory behind the various FRET microscopy and spectroscopy techniques, and the practical aspects of using the techniques and analyzing the results. The critical tricks for obtaining a good FRET image and precisely quantitating the signals from living specimens at the nanomolecular level are explained. Valuable information about the preparation of biological samples used for FRET image analysis is also provided. The methods covered include different types of microscopy systems and detectors (wide-field, confocal, multi-photon) as well as specialized techniques such as photobleaching FRET, FLIM-FRET microscopy, spectral imaging FRET, single molecule FRET, and time and image correlation spectroscopy. Starting from the basics, the chapters guide readers through the choice of probes to be used for FRET experiments and the selection of the most suitable experimental approaches to address specific biological questions. Up-to-date, consistently organized, and well-illustrated, this unique book will be welcomed by all researchers who wish to use FRET microscopy and spectroscopy techniques.
    • International Review of Cytology

      • 1st Edition
      • Volume 244
      • July 13, 2005
      • Kwang W. Jeon
      • English
      • Hardback
        9 7 8 0 1 2 3 6 4 6 4 8 4
      • Paperback
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      • eBook
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      International Review of Cytology presents current advances and comprehensive reviews in cell biology – both plant and animal. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. Articles in this volume address Plastid RNA polymerases, promoters, and transcription regulators in higher plants; Maintenance of Golgi Apparatus Structure in the Face of Continuous Protein Recycling to the ER: Making Ends Meet; Nucleocytoplasmic trafficking in plant cells; Building in vitro models of organs; Mitrochondria-drived organelles in protists and fungi; The flagellum of trypanosomes; and Regulation of growth and differentiation in Dictyostelium.
    • Planar Cell Polarization during Development

      • 1st Edition
      • Volume 14
      • July 12, 2005
      • Marek Mlodzik
      • English
      • Hardback
        9 7 8 0 4 4 4 5 1 8 4 5 3
      • eBook
        9 7 8 0 0 8 0 4 5 8 6 1 8
      Cellular polarization is key to all cellular functions. Our perceptions, which are derived from our senses, depend on the proper cellular polarization of our sense organs, such as the eyes or ears. Much of this book examines the different aspects in cellular polarization and its researched role in the Drosophila, where the first planar cellular polarity (PCP) gene was discovered over 20 years ago. Topics also include: From flies to man: how we are polarized, Marking an embryo work, Cellular polarization at its functional best, Hearing and seeing your environment, and From a cell to an organ.This series represents timely issues in developmental biology. It provides annual reviews of selected topics, written from the perspectives of leading investigators in the field of development.
    • Nonviral Vectors for Gene Therapy, Part 2

      • 2nd Edition
      • Volume 54
      • July 7, 2005
      • Leaf Huang + 2 more
      • English
      • Hardback
        9 7 8 0 1 2 0 1 7 6 5 4 0
      • eBook
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      The field of non-viral vector research has rapidly progressed since the publication of the first edition. This new edition is expanded to two separate volumes that contain in-depth discussions of different non-viral approaches, including cationic liposomes and polymers, naked DNA and various physical methods of delivery, as well as a comprehensive coverage of the molecular biological designs of the plasmid DNA for reduced toxicity, prolonged expression and tissue or disease specific genes. New developments such as the toxicity of the non-viral vectors and recent advances in nucleic acid therapeutics are fully covered in these volumes.
    • Caveolae and Lipid Rafts: Roles in Signal Transduction and the Pathogenesis of Human Disease

      • 1st Edition
      • Volume 36
      • July 6, 2005
      • Philippe Frank + 2 more
      • English
      • Paperback
        9 7 8 0 4 4 4 5 6 0 9 3 3
      • Hardback
        9 7 8 0 4 4 4 5 1 5 0 0 1
      • eBook
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      Caveolae (latin for little caves) are small structures found at the surface of cells. They are responsible for the regulation of important metabolic pathway. As a consequence, they may play a critical role in several human diseases such as atherosclerosis, cancer, diabetes, and muscular dystrophies. This book analyzes the role and function of caveolae in these aspects and serves as the first textbook currently available on caveolae/caveolin.
    • Biotechnology Annual Review

      • 1st Edition
      • Volume 11
      • July 6, 2005
      • M. Raafat El-Gewely
      • English
      • Hardback
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      • eBook
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      Biotechnology is a diverse, complex and rapidly evolving field. Students and experienced researchers alike face the challenges of staying on top of developments in their field of specialty and maintaining a broader overview of the field as a whole. Volumes containing competent reviews on a diverse range of topics in the field fulfill the dual role of broadening and updating biotechnologists’ knowledge. The current volume is an excellent example of such a book. The topics covered range from classical issues in biotechnology - such as, vehicles for the production of biotechnology products and methods for their detection, separation and analysis - to topics that are focused on the role of biotechnology in the health sciences. The information presented in this book will therefore will be of great value to both experienced biotechnologists and biotechnologists in training.
    • Selected Topics in the History of Biochemistry: Personal Recollections IX

      • 1st Edition
      • Volume 44
      • June 28, 2005
      • English
      • Hardback
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      • eBook
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      This book is the latest volume in the highly successful series Comprehensive Biochemistry. It provides a historical and autobiographical perspective of the developments in the field through the contributions of leading individuals who reflect on their careers and their impact on biochemistry. Volume 44 is essential reading for everyone from graduate student to professor, placing in context major advances not only in biochemical terms but in relation to historical and social developments. Readers will be delighted by the lively style and the insight into the lives and careers of leading scientists of their time.