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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

BooksJournals

    • International Review of Cell and Molecular Biology

      • 1st Edition
      • Volume 285
      • October 27, 2010
      • Kwang W. Jeon
      • English
      • Hardback
        9 7 8 0 1 2 3 8 1 0 4 7 2
      • eBook
        9 7 8 0 1 2 3 8 1 2 5 1 3
      International Review of Cell and Molecular Biology presents current advances and comprehensive reviews in cell biology--both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Impact factor for 2008: 4.935.

    • Invertebrate and Vertebrate Eye Development

      • 1st Edition
      • Volume 93
      • October 27, 2010
      • English
      • Hardback
        9 7 8 0 1 2 3 8 5 0 4 4 7
      • eBook
        9 7 8 0 1 2 3 8 5 0 4 5 4
      Vision is our primary sensory modality, and we are naturally curious as to how the visual system assembles. The visual system is in many ways remarkably simple, a repeating assemblage of neurons and support cells that parse the visual field through precision and redundancy. Through this simplicity the eye has often led the way in our exploration of how an organ is assembled. Eye development has therefore long been a favorite for exploring mechanisms of cell fate choice, patterning and cell signaling.This volume, which is part of the Current Topics in Developmental Biology series, highlights the exceptional advances over the past 20 years. Chapters emphasize our knowledge of transcription factors and how these generate networks to direct the eye field and associated structures. Topics such as cell fate specification are also explored, along with the potential of Drosophila as a model for lens formation and the progress made in using the Drosophila eye to examine planar cell polarity.

    • Analysis of Complex Disease Association Studies

      • 1st Edition
      • October 20, 2010
      • Eleftheria Zeggini + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 3 7 5 1 4 2 3
      • eBook
        9 7 8 0 1 2 3 7 5 1 4 3 0
      According to the National Institute of Health, a genome-wide association study is defined as any study of genetic variation across the entire human genome that is designed to identify genetic associations with observable traits (such as blood pressure or weight), or the presence or absence of a disease or condition. Whole genome information, when combined with clinical and other phenotype data, offers the potential for increased understanding of basic biological processes affecting human health, improvement in the prediction of disease and patient care, and ultimately the realization of the promise of personalized medicine. In addition, rapid advances in understanding the patterns of human genetic variation and maturing high-throughput, cost-effective methods for genotyping are providing powerful research tools for identifying genetic variants that contribute to health and disease. This burgeoning science merges the principles of statistics and genetics studies to make sense of the vast amounts of information available with the mapping of genomes. In order to make the most of the information available, statistical tools must be tailored and translated for the analytical issues which are original to large-scale association studies. Analysis of Complex Disease Association Studies will provide researchers with advanced biological knowledge who are entering the field of genome-wide association studies with the groundwork to apply statistical analysis tools appropriately and effectively. With the use of consistent examples throughout the work, chapters will provide readers with best practice for getting started (design), analyzing, and interpreting data according to their research interests. Frequently used tests will be highlighted and a critical analysis of the advantages and disadvantage complimented by case studies for each will provide readers with the information they need to make the right choice for their research. Additional tools including links to analysis tools, tutorials, and references will be available electronically to ensure the latest information is available.

    • Regenerative Nephrology

      • 1st Edition
      • October 20, 2010
      • Michael S. Goligorsky
      • English
      • Paperback
        9 7 8 0 1 2 8 1 0 1 9 6 4
      • Hardback
        9 7 8 0 1 2 3 8 0 9 2 8 5
      • eBook
        9 7 8 0 1 2 3 8 0 9 2 9 2
      Progression of chronic diseases in general and chronic kidney disease in particular has been traditionally viewed in the light of various contributors to development of glomerulosclerosis and tubulointerstitial scarring culminating in renal fibrosis. Indeed, this dogma prevailed for decades underscoring experimental attempts to halt fibrotic processes. Breakthrough investigations of the past few years on stem/progenitor cell involvement in organ regeneration caused a conceptual shift in tackling the mechanisms of nephrosclerosis. It has become clear that the rate of progression of chronic kidney disease is the net sum of the opposing trends: degenerative fibrotic processes and regenerative repair mechanisms. The latter part of this equation has been by and large ignored for years and only recently attracted investigative attention. This book revisits the problem of kidney disease by focusing on regenerative mechanisms in renal repair and on the ways these regenerative processes can become subverted by an intrinsic disease process eventuating in its progression. Cutting-edge investigations are summarized by the most experienced international team of experts.

    • Advances in Clinical Chemistry

      • 1st Edition
      • Volume 52
      • October 14, 2010
      • English
      • Hardback
        9 7 8 0 1 2 3 8 0 9 4 8 3
      • eBook
        9 7 8 0 1 2 3 8 0 9 4 9 0
      Volume 47 in the internationally acclaimed Advances in Clinical Chemistry contains chapters submitted from leading experts from academia and clinical laboratory science. Authors are from a diverse field of clinical chemistry disciplines and diagnostics, ranging from basic biochemical exploration to cutting-edge microarray technology.

    • Epigenetics and Cancer, Part B

      • 1st Edition
      • Volume 71
      • October 14, 2010
      • English
      • Hardback
        9 7 8 0 1 2 3 8 0 8 6 4 6
      • eBook
        9 7 8 0 1 2 3 8 0 8 6 5 3
      Genes interact with the environment, experience, and biology of the brain to shape an animal’s behavior. This latest volume in Advances in Genetics, organized according to the most widely used model organisms, describes the latest genetic discoveries in relation to neural circuit development and activity.

    • Epigenetics and Cancer, Part A

      • 1st Edition
      • Volume 70
      • October 14, 2010
      • English
      • Hardback
        9 7 8 0 1 2 3 8 0 8 6 6 0
      • eBook
        9 7 8 0 1 2 3 8 0 8 6 7 7
      Genes interact with the environment, experience, and biology of the brain to shape an animal’s behavior. This latest volume in Advances in Genetics, organized according to the most widely used model organisms, describes the latest genetic discoveries in relation to neural circuit development and activity.

    • International Review of Cell and Molecular Biology

      • 1st Edition
      • Volume 284
      • October 12, 2010
      • Kwang W. Jeon
      • English
      • Hardback
        9 7 8 0 1 2 3 8 1 2 5 2 0
      • eBook
        9 7 8 0 1 2 3 8 1 2 5 3 7
      International Review of Cell and Molecular Biology presents current advances and comprehensive reviews in cell biology--both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Impact factor for 2008: 4.935.

    • Cryo-EM Part B: 3-D Reconstruction

      • 1st Edition
      • Volume 482
      • September 30, 2010
      • English
      • Hardback
        9 7 8 0 1 2 3 8 4 9 9 1 5
      • eBook
        9 7 8 0 1 2 3 8 4 9 9 2 2
      This volume is dedicated to a description of the instruments, samples, protocols, and analyses that belong to cryo-EM. It emphasizes the relatedness of the ideas, instrumentation, and methods underlying all cryo-EM approaches, which allow practitioners to easily move between them. Within each section, the articles are ordered according to the most common symmetry of the sample to which their methods are applied.

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