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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

    • Stress, Neuropeptides, and systemic disease

      • 1st Edition
      • December 2, 2012
      • James McCubbin
      • English
      • Paperback
        9 7 8 0 1 2 4 1 4 4 8 2 8
      • eBook
        9 7 8 0 3 2 3 1 4 8 0 0 9
      Stress, Neuropeptides, and Systemic Disease traces the development of the neuropeptide hypothesis from its anatomical substrate to its functional correlates in animal and pre-clinical human models of stress-induced disease. The book contains articles that discuss the different aspects and findings on the study of neuropeptides such as the histochemical localization of peptide-containing cells and peptidergic receptors; the current concepts in hypothalamo-pituitar... axis regulation; neuropeptides involved in stress and their distribution in the mammalian central nervous system; and neuropeptide-mediate... regulation of the neuroendocrine and autonomic responses to stress. The methods of measuring neuropeptides and their metabolism; stress responses and the pathogenesis of arthritis; brain peptides and gastrointestinal transit; and diminished opioid inhibition of blood pressure and pituitary function in hypertension development are presented as well. Physicians, neurobiologists, pharmacologists, and biological scientists will find the book very interesting.
    • General Principles

      • 1st Edition
      • December 2, 2012
      • Ronald Aloia
      • English
      • Paperback
        9 7 8 0 1 2 4 3 3 4 5 1 9
      • eBook
        9 7 8 0 3 2 3 1 5 7 6 3 6
      Membrane Fluidity in Biology, Volume 2: General Principles provides an introduction to the fundamental concepts of membrane fluidity. Key topics discussed include lateral phase separations and phase transitions; hydrophobic and electrostatic effects of membrane lipid-protein interactions; isothermal phase transitions and the effects of ionic factors; and the influence of such components as cholesterol, phospholipids, fatty acids, and cellular water on the parameters of membrane fluidity. Each of these topics is elaborated in detail to provide a unique insight into the factors influencing the thermal molecular motions of membrane components, and hence cellular membrane function. Because such activities as membrane transport, enzyme kinetics, and receptor function are modulated by the physical state of the membrane lipids and proteins, a thorough comprehension of the molecular aspects of membrane fluidity is necessary to evaluate the arcane aspects of membrane-related cellular activities. This book will be useful to scientists and researchers concerned with the molecular principles of cellular and organelle function. It also provides an appropriate background for Volume 3, Cellular Aspects and Disease Processes, and for subsequent discussion of the relationship of membrane fluidity to environmental parameters, drugs, anesthetics, and other exogenous agents.
    • Rodent Malaria

      • 1st Edition
      • December 2, 2012
      • R. Killick-Kendrick
      • English
      • Paperback
        9 7 8 0 1 2 4 3 1 2 5 8 6
      • eBook
        9 7 8 0 3 2 3 1 5 0 5 7 6
      Rodent Malaria reviews significant findings concerning malaria parasites of rodents, including their taxonomy, zoogeography, and evolution, along with life cycles and morphology; genetics and biochemistry; and concomitant infections. This volume is organized into eight chapters and begins by sketching out the history of the discovery of rodent as well as aspects of parasitology, immunology, and chemotherapy. These concepts are investigated two decades following Ignace Vincke's major discovery and Meir Yoeli's successful establishment of the method of cyclical transmission of the parasite. The following chapters focus on the taxonomy and systematics of the subgenus Vinckeia, with reference to the concepts of species and subspecies of animals and the degree to which they apply to malaria parasites, in particular to those of rodents. The discussion then shifts to how the rodent malaria parasites provide a unique insight into the subcellular organization of Plasmodium species, the use of rodent malaria as an experimental model to study immunological responses, and infectious agents that interact with malaria parasites. The book concludes with a chapter on malaria chemotherapy, with emphasis on the value of rodent malaria in antimalarial drug screening and the use of antimalarial drugs as biological probes. This book will be of interest to protozoologists and physicians as well as those from other disciplines including biochemistry, immunology, pharmacology, cell biology, and genetics.
    • Lipoxygenases and Their Products

      • 1st Edition
      • December 2, 2012
      • Stanley Crooke
      • English
      • Paperback
        9 7 8 0 1 2 4 3 3 3 4 2 0
      • eBook
        9 7 8 0 3 2 3 1 5 6 5 3 0
      Lipoxygenases and Their Products provides a cogent summary of the advances in understanding lipoxygenases and their products, emphasizing their pharmacology and pathophysiology; regulation and structure; physiological role; and receptors and receptor antagonists. This text also reviews the literature where specific receptor antagonists (as opposed to enzymatic inhibitors) have been used to characterize the pharmacologic action and the pathophysiologic roles of some of lipoxygenase products of arachidonic acid metabolism. This book is organized into 11 chapters and begins with an overview of the biochemical, pharmacological, and pathophysiological aspects of 5-lipoxygenase products of arachidonic acid metabolism in the respiratory, cardiovascular, renal, gastrointestinal, and central nervous systems. The discussion then shifts to human 5-lipoxygenase, emphasizing this enzyme purification, stimulatory factors, and membrane translocation. The reader is methodically introduced to 5-lipoxygenase activity in rats and pigs; the potential and therapeutic value of 5-lipoxygenase inhibitors; the distribution of 15-lipoxygenase in cells or tissues; and products formed through the 15-lipoxygenase pathway. This book also considers lipoxins and third-generation peptidoleukotriene receptor antagonists, and then concludes with a summary of the physiological and pathophysiological effects of leukotrienes and lipoxins in a variety of organs. This book is of interest to scientists interested in arachidonic acid and its metabolites, to scientists engaged in drug discovery-and-develo... activities in academia and the pharmaceutical industry, and to clinicians interested in diseases associated with leukotrienes and related products.
    • The Carbohydrates

      • 2nd Edition
      • December 2, 2012
      • Ward Pigman
      • English
      • Paperback
        9 7 8 0 1 2 3 9 4 1 8 0 0
      • eBook
        9 7 8 0 3 2 3 1 6 1 7 2 5
      The Carbohydrates: Chemistry and Biochemistry, Second Edition, Volume IIB is a complete revision of a previous work that was based on “The Chemistry of the Carbohydrates”. This volume is composed of 10 chapters that cover the chemical and biochemical aspects of the main types of carbohydrates. This book begins with considerable chapters on the main types of carbohydrates, including starch, glycogen, pectins, plant gums, plant, algal, and microbial polysaccharides, as well as monosaccharides. These chapters specifically tackle the occurrence, isolation, production, properties, and reactions of these carbohydrates. This volume includes chapters on the fields of glycolipids and glycoproteins. The concluding chapters cover the official nomenclature rules for carbohydrates and for enzymes having carbohydrates as substrates. This volume is of great value to carbohydrates scientists and researchers.
    • The Hormonal Control of Gene Transcription

      • 1st Edition
      • Volume 6
      • December 2, 2012
      • P. Cohen + 1 more
      • English
      • Paperback
        9 7 8 0 4 4 4 5 6 6 3 7 9
      • eBook
        9 7 8 0 4 4 4 5 9 9 8 1 0
      Over the past few years there have been considerable advances in our understanding of cellular control mechanisms, and current research is now linking areas of biology that were previously thought of as being quite separate. Molecular Aspects of Cellular Regulation is a series of occasional books on multidisciplinary topics which illustrate general principles of cellular regulation. Previous volumes described Recently Discovered Systems of Enzyme Regulation by Reversible Phosphorylation (Volumes 1 and 3), The Molecular Actions of Toxins and Viruses (Volume 2), Molecular Mechanisms of Transmembrane Signalling (Volume 4) and Calmodulin (Volume 5). This sixth volume, The Hormonal Control of Gene Transcription, has now been published to highlight recent important advances in our understanding of this topic which is linking two of the most active areas of current biochemical and molecular biological research (hormone action and gene transcription) and leading to the emergence of unifying concepts.
    • Role Gastrointestinal Tract Nutrient Delivery

      • 1st Edition
      • December 2, 2012
      • Morris Green
      • English
      • eBook
        9 7 8 0 3 2 3 1 4 0 4 6 1
      The Role of the Gastrointestinal Tract in Nutrient Delivery contains the proceedings of the third annual Bristol-Myers Symposium on Nutrition Research, held on December 1-2, 1983 in Washington, D.C. Contributors focus on the knowledge and research findings concerning the role of the gastrointestinal tract in nutrient delivery. This text is organized into 15 chapters and addresses topics such as gastrointestinal motility; hormonal regulation of growth and function; the mechanisms of digestion and absorption; and the diverse effects of intestinal contents on nutrient absorption and antigenic response. The discussion begins with an overview of the gastrointestinal tract, with emphasis on factors that affect the growth of gastrointestinal mucosa and the implications for nutrition. This book then turns to kinetic and biochemical parameters related to the development of several diseases of the gastrointestinal tract. The reader is also introduced to the basic aspects of organization of the systems in which peptides act as regulators of digestion; the role of endogenous prostaglandins in the gastrointestinal tract; and gastric secretion. A chapter on the age-related functions of digestive tract organs concludes the book. This book will be of value to physicians and scientists as well as students and researchers who have an interest in the crucial role of the gastrointestinal tract in converting food into the nutrients the body uses to sustain its functions.
    • Laboratory Methods in Cell Biology

      • 1st Edition
      • Volume 112
      • November 28, 2012
      • English
      • Hardback
        9 7 8 0 1 2 4 0 5 9 1 4 6
      • eBook
        9 7 8 0 1 2 4 0 5 5 4 9 0
      Cell biology spans among the widest diversity of methods in the biological sciences. From physical chemistry to microscopy, cells have given up with secrets only when the questions are asked in the right way! This new volume of Methods in Cell Biology covers laboratory methods in cell biology, and includes methods that are among the most important and elucidating in the discipline, such as transfection, cell enrichment and magnetic batch separation.
    • Systems Biology of Bacteria

      • 1st Edition
      • Volume 39
      • November 28, 2012
      • English
      • Hardback
        9 7 8 0 0 8 0 9 9 3 8 7 4
      • eBook
        9 7 8 0 1 2 4 0 7 2 0 1 5
      Focusing on the systems biology of bacteria and microorganisms, the 39th volume of Methods in Microbiology investigates the interface between molecular biology, bioinformatics, and modelling and predicting behavior. This cutting-edge research area is of extreme importance to the field and is developing quickly.
    • Eukaryotic RNases and their Partners in RNA Degradation and Biogenesis

      • 1st Edition
      • Volume 32
      • November 27, 2012
      • English
      • Hardback
        9 7 8 0 1 2 4 0 4 7 4 1 9
      • eBook
        9 7 8 0 1 2 4 0 4 7 4 4 0
      This special volume of The Enzymes is targeted towards researchers in biochemistry, molecular and cell biology, pharmacology, and cancer. This thematic volume discusses Eukaryotic RNases and their partners in RNA degradation and biogenesis.