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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

    • Vitamin D

      • 1st Edition
      • December 2, 2012
      • Anthony Norman
      • English
      • Paperback
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      Vitamin D: The Calcium Homeostatic Steroid Hormone provides a continuing coordinated group of edited critiques of the dynamic state of the science and art of nutrition. The most recent basic advances will be reviewed within the broad framework of the scientific knowledge of food and nutrition, including its application to man, individually and societally. The volumes, authored singly or by invited contributors, will appeal to serious scholars concerned with pure or applied nutrition. This volume comprises 13 chapters, with the first discussing the progress of vitamin D-cholecalciferol from vitamin to steroid hormone. Succeeding chapters then discuss the biological and chemical assay of vitamin D, its metabolites, and analogs; metabolism of vitamin D; and the tissue and subcellular localization of vitamin D and its metabolites. Other chapters cover binding proteins and receptors for vitamin D and its metabolites; interrelationships between vitamin D and other hormones; intestinal effects of vitamin D; vitamin D actions in the kidney; vitamin D actions on bone; and vitamin D and its clinical relationships. This book will be of interest to practitioners in the fields of chemistry, nutrition, and medicine.
    • Lung Metabolism

      • 1st Edition
      • December 2, 2012
      • Alain Junod
      • English
      • Paperback
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      Lung Metabolism: Proteolysis and Antiproteolysis Biochemical Pharmacology Handling of Bioactive Substances focuses on studies on the response of the lung relative to the management of bioactive substances. Divided into three sections with 35 chapters, the book focuses first on proteolysis and antiproteolysis in the lung. Concerns include properties and role of antiproteases; role of leucoproteases in the development of emphysema; and the genetic and clinical considerations of alpha1-antitrypsin deficiencies. The second section focuses on biochemical pharmacology of the lung. Concerns include pulmonary drug-metabolizing enzymes; carrier for oxygen and carbon monoxide in the lung; and metabolism of drugs administered by aerosol. The last section looks at the handling of bioactive substances by the lung. Covered areas include the pharmacokinetic function of the lung; biosynthesis and metabolism of prostaglandins in the lung; and importance and nature of the mechanism of inactivation of prostaglandins in the lung. The book is a vital source of information for readers interested in studying the metabolism of the lung.
    • Biochemistry of the amino acids

      • 2nd Edition
      • December 2, 2012
      • Alton Meister
      • English
      • eBook
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      Biochemistry of the Amino Acids, Second Edition, Volume II focuses on the trends in research on amino acids and biochemistry. Given considerations are incorporation of amino acids into proteins, amino acid sequences, and discovery of amino acids. The first part of the book deals with intermediary metabolism of amino acids. Particularly noted are alanine, aspartic, adenylosuccinic, hydroxyaspartic acids, and asparagine. The book also has discussions on glutamic acid, glutamine, glycine, serine, and sarcosine. The processes and syntheses involved in these acids are noted. Another part of the book focuses on the formation, degradation, reactions, and conversion of acids. The processes and experiments discussed are supported by numerical analysis, and the biosynthesis of acids in microorganisms is also considered. The book also notes some disorders of amino acid metabolism in humans. These disorders include cystinuria, glycinuria, ammonemia, prolinemia, maple syrup urine disease, and homocystinuria. Discussions focus on how these diseases develop and the symptoms associated with them. The book is a vital source of data for readers interested in the study of amino acids.
    • Biochemistry of Human Cancer

      • 1st Edition
      • December 2, 2012
      • Oscar Bodansky
      • English
      • Paperback
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      Biochemistry of Human Cancer focuses on advances in the application of biochemistry to the study of human cancers, such as neoplastic immunoglobulinopathi... cancer of the bladder, tumors of the neural crest, leukemias and lymphomas, and neoplasms of the bone. It also examines certain features of human cancer ranging from general metabolic characteristics to enzymic aspects and immunochemical considerations. Organized into 18 chapters, this book begins with an overview of the general metabolic features of cancer, with emphasis on the metabolism of lipids, proteins, and carbohydrates. It then discusses the important biochemical aspects of pulmonary and prostatic neoplasms, including the serum acid and alkaline phosphatase activities of prostatic carcinoma. The remaining chapters look at the role of enzymes and immunoglobulins in cancer, the tryptophan metabolism in cancer of the bladder and the carcinoid syndrome, the link between amino acid metabolism and tumors of the neural crest, and the neoplasms of the digestive tract and the accessory organs (pancreas and liver). The book explains the metabolism of purines and pyrimidines in cancer, hypercalcemia in neoplastic disease without evidence of bone metastases, and neoplasms of other organs, such as the pituitary gland, thyroid, testis, and adrenal cortex. Brief case reports from the literature are included to illustrate correlations between biochemical and clinical findings. Scientists, biochemists, and clinical investigators concerned with the biochemistry of human cancer will find this book highly informative.
    • Membranes, Mitochondria, and Connective Tissues

      • 1st Edition
      • December 2, 2012
      • Isidore Gersh
      • English
      • Paperback
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      Submicroscopic Cytochemistry, Volume II: Membranes, Mitochondria, and Connective Tissues presents laboratory findings and theoretical aspects of the cytochemistry of cellular membranes, mitochondria, and connective tissues. Emphasis is on the molecular and macromolecular organization of cellular membranes, along with the origin and distribution of the major macromolecular aggregates of connective tissue. This volume consists of 11 chapters and begins by discussing the results of cytochemical studies on lipid and protein components of membranes in acinar and hepatic cells of the murine pancreas. The following chapters focus on densitometric studies of lipid membranes in pancreatic acinar cells of the mouse; the distribution of lipids and proteins in mitochondria of hepatic and exocrine pancreatic cells of adult mice, and of nucleic acids in mitochondria of embryonic cells; and possible precursor granules in fibroblasts, chondrocytes, and osteoblasts. The distribution of DNA and of soluble and insoluble RNAs in chondrocytes of the epiphyseal plate of the rat tibia is also examined, along with vascularity in tendons of young rats. This monograph will be of interest to cytochemists, biochemists, and molecular biologists.
    • Chemistry of the Carbohydrates

      • 1st Edition
      • December 2, 2012
      • Tanveer Syeda-Mahmood
      • English
      • Paperback
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      Chemistry of the Carbohydrates focuses on the compositions, chemical reactions, structures, and characteristics of carbohydrates. The monograph first traces the development of carbohydrate chemistry, and then gives emphasis to general chemistry, nomenclature, and definitions. The book discusses the occurrences, properties, structures, and stereochemistry of monosaccharides. Structures of glucose and fructose; stereochemistry; ring structure of sugars; the sugars found in solutions; and synthetic sugars are considered. The monograph also looks at the properties, structures, and stereochemistry of esters, glycosides, full acetals, and thioacetals. The book proceeds with discussions on polyols, inositols, and compounds. Isomerization and representation of configurations; proofs of structure and configuration; and biochemistry are discussed. The monograph closes with the discussions on acids, oligosaccharides, glycosides, starches, and polysaccharides. The compositions, structures, and chemical reactions of these substances are noted. The book can best serve the interest of readers, research workers, and graduate students who want to explore the compositions, properties, and chemical reactions of carbohydrates.
    • Nucleic Acids, Proteins and Carbohydrates

      • 1st Edition
      • December 2, 2012
      • F. Korte
      • English
      • Paperback
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      • Hardback
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      Methodicum Chimicum, Volume 11: Natural Compounds, Part 1: Nucleic acids, Proteins and Carbohydrates is devoted to the methods of structural determinations and syntheses of natural products. This text contains four chapters that include a short discussion of the principles of well-proved analytic procedures. It primarily describes the chemistry and biochemistry of nucleic acids, proteins, carbohydrates, and lipids. Other general topics covered include the components, chemical synthesis, sequences, primary structure, and classification of these macromolecules. This book is of value to chemists and scientists who works in associated areas, including medicine.
    • Neural and Behavioral Specificity

      • 1st Edition
      • December 2, 2012
      • Gilbert Gottfried
      • English
      • Paperback
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      • Hardback
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      Studies on the Development of Behavior and the Nervous System, Volume 3: Neural and Behavioral Specificity covers the fundamental concepts and principles of neural and behavioral specificity in various species, including fish, amphibians, birds, and mammals. This book is composed of five sections encompassing eight chapters. The first section discusses the historical developments of neurobiological research; the role of visual experience in the functional development of the visual system; and the interrelationship between maturation and experience in development. The second section examines the developmental control of synaptogenesis and the precise neural cell connections. This section further addresses the main discrepancies in the evidence and interpretations of the retinotectal specificity based on the chemoaffinity theory. The third section discusses the role of visual experience in the development of the mammalian striate cortex, with particular emphasis on the incorporation of ontogenetic information into the developing nervous system. This topic is followed by an overview of the properties of kitten visual neurons and of some evidence for plasticity in the developing visual systems of frogs, monkeys, and man. The concluding sections cover the theories of innate species-specific behavioral development and the ontogeny of mammalian perceptual development. Neurodevelopmental biologists and researchers will find this book invaluable.
    • Glutamine: Metabolism, Enzymology, and Regulation

      • 1st Edition
      • December 2, 2012
      • Jaime Mora
      • English
      • Paperback
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      Glutamine: Metabolism, Enzymology, and Regulation presents significant contributions on the metabolism, enzymology, and regulation of glutamine of microorganisms to higher animals. The book is a collection of papers presented during the scientific symposium of the fiftieth anniversary of the granting of the autonomy of the University of Mexico, held in Hacienda Galindo, Queretaro, Mexico in November 1979. The monograph covers glutamine metabolism centered mainly in enzymatic studies on glutamine synthetase and the enzymes that utilize glutamine; the model of cascade control of glutamine synthetase in Escherichia coli; the mechanisms that control gene expression of glutamine synthetase and its relation to nitrogen metabolism in prokaryotes; the relationship between the structure and function of glutamine synthetase in eukaryotic microorganisms; nitrogen and glutamine metabolism in plants; the role of glutamine in the animal body; and the synthesis of glutamine in animal tissues. Biologists, botanists, and zoologists will find the compendium very insightful.
    • Basic Mechanisms in Hearing

      • 1st Edition
      • December 2, 2012
      • Aage Moller
      • English
      • Hardback
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      • eBook
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      Basic Mechanisms in Hearing is a collection of papers that discusses the function of the auditory system covering its ultrastructure, physiology, and the mechanism's connection with experimental psychology. Papers review the mechanics, morphology, and physiology of the cochlear, including the physiology of individual hair cells and their synapses. One paper examines the combined physiological and anatomical studies of stimulus coding in the mammalian auditory nervous system. The results of these studies pertain to the latency, frequency selectivity, and time pattern of responses to short tone bursts. Other research compare the cochlear nerve, behavioral, and psychophysical frequency selectivity which show that frequency selectivity of the auditory system occurs at the level of the cochlear nerve, becoming downgraded in end-organ deafness. Other papers discuss neural coding at higher levels such as the feature extraction in the auditory system of bats. Some papers also analyze the specialized hearing mechanisms in animals, for example, the echolocation of bats and in some insects, the function of the swimbladder in fish hearing, as well as the "invertebrate frequency analyzer" in the locust ear. Physiologists, neurophysiologists, neurobiologists, general medical practioners, and EENT specialists will find this collection valuable.