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Elsevier

Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

  • Explainable AI in Clinical Practice

    Advanced Applications and Future Directions
    • 1st Edition
    • Saurav Mallik + 4 more
    • English
    Explainable AI in Clinical Practice: Advanced Applications and Future Directions builds on foundational concepts to explore the practical implementation and emerging trends of transparent AI in healthcare. Featuring contributions from leading experts, this volume presents advanced methodologies, real-world case studies across various medical specialties, and strategies for overcoming ethical, regulatory, and operational challenges. The book offers comprehensive frameworks for integrating explainable AI into clinical workflows, emphasizing trust, patient understanding, and regulatory compliance. In addition, it examines future technologies such as federated learning, multimodal systems, and human-AI collaboration, providing insights into the evolving landscape of AI in medicine.Essential for healthcare professionals, researchers, and policymakers, this volume aims to accelerate the responsible adoption of explainable AI, ultimately enhancing patient care, clinical decision-making, and healthcare system efficiency.

  • Laboratory Diagnosis of Inherited Metabolic Diseases

    • 2nd Edition
    • Uttam Garg + 2 more
    • English
    Laboratory Diagnosis of Inherited Metabolic Diseases, Second Edition provides the most up-to-date guidance on laboratory test selection and interpretation, illustrated metabolic pathways, and information on clinical presentation, genetics, pathogenesis, treatment, and prognosis of these diseases. Since the first edition and the expansion of newborn screening, an increasing number of healthcare providers are encountering metabolic disorders, so selecting and interpreting tests can be challenging. This fully revised edition offers simple and practical approaches to understanding metabolic diseases, assisting in the selection of tests for confirmatory diagnosis and clinical follow-up.Biochemica... genetic testing is a key laboratory medicine discipline for evaluating, diagnosing, and treating inherited metabolic diseases (IMDs). These tests are complex and specialized, and use a variety of specimens, including blood, urine, plasma, and cerebrospinal fluid. The tests evaluate enzyme activity, protein function, and metabolite levels, such as fatty acids, amino acids, and organic acids.

  • Deep Learning in Bioinformatics

    Techniques and Applications in Practice
    • 2nd Edition
    • Habib Izadkhah
    • English
    Deep Learning in Bioinformatics: Techniques and Applications in Practice, Second Edition explores how deep learning can be utilized for addressing important problems in bioinformatics, including drug discovery, de novo molecular design, sequence analysis, protein structure prediction, gene expression regulation, protein classification, biomedical image processing and diagnosis, biomolecule interaction prediction, and in systems biology. The book also presents theoretical and practical successes of deep learning in bioinformatics, pointing out problems and suggesting future research directions. This updated edition includes several new chapters, applications, and examples for new Deep Learning advances and techniques.Dr. Izadkhah provides valuable insights and will help researchers use deep learning techniques in their biological and bioinformatics studies.

  • Advances in Biomembranes and Lipid Self-Assembly

    • 1st Edition
    • Volume 43
    • English
    Advances in Biomembranes and Lipid Self-Assembly, Volume 43 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Subjects in this new release cover engineered probiotics for producing phosphoinositol-sn-l... as biosurfactant modulators: Their hydropathy, in potentiating surface tension and scaffold properties into model emulsions.

  • Human Histology

    A Text and Atlas for Physicians and Scientists
    • 2nd Edition
    • Bertalan Dudas
    • English
    Human Histology: A Text and Atlas for Physicians and Scientists, Second Edition offers full-page, low-magnification photomicrographs for organs and tissues surrounded by high-power images of the same sample. Each specimen is followed by a compact and simple-to-read description of the structures identified on the micrographs, offering a clear, visual understanding. In addition to 300 outstanding images, this new edition includes schematics of each organ for a more detailed representation, making it easier to learn. This is an invaluable resource for every clinical researcher and pathologist in need of accessible, relatively simple, but detailed information on normal histology in different organs systems.

  • Sustainable Microalgal Biorefinery

    • 1st Edition
    • Naim Rashid + 1 more
    • English
    Sustainable Microalgal Biorefinery, the latest release in Elsevier's Developments in Microbial Cell Factories: From Design to Commercial Production series, provides an overview of microalgae at the cellular level, along with their potential uses across a range of industries. Beginning with an introduction to microalgae biorefinery systems and the latest research and limitations, the book delves into the fundamental aspects of microalgae and their potential applications, such as biofuel production, water treatment, bioplastics production, carbon capture, aquaculture feed, and high-value bioproducts, including food, biotechnology, and pharmaceuticals. Photobioreactors design for microalgae are also covered, as well as genetic modifications to achieve desired bio-products. The book also focuses on assessing the social, environmental, and economic sustainability of microalgae technologies and how microalgae contributes to achieving UN SDG goals. This latest volume provides researchers with valuable insights into the transformation of traditional algal research and the recent trends of resource recovery and integrated technology that can be utilized to enhance sustainability and commercialization potential of microalgae.

  • Phytochemicals and Hallmarks of Cancer

    From Molecules to Medicine
    • 1st Edition
    • Gautam Sethi + 1 more
    • English
    Phytochemicals and Hallmarks of Cancer: From Molecules to Medicine delves into the potential of phytomedicine to effectively address both established and emerging hallmarks of cancer, offering valuable insights into their translational applications from bench to bedside. The book provides comprehensive information about how the plant-derived product tackles cancer by targeting different hall markers that drive cancer progression. In 12 chapters the book not only describes the implications of plant products on cancer immunotherapy, gives insight in the hurdles in clinical translating plant derived products for cancer therapy, but also focuses on the therapeutic aspects of phytochemicals, providing insights into how understanding of mechanism of actions of phytochemicals can aid to develop innovative therapies.By addressing these knowledge and information needs Phytochemicals and Hallmarks of Cancer: From Molecules to Medicine is designed to be accessible to clinicians and researchers alike in the field of phytochemical applications in medicine.

  • Biomechanics and Mechanobiology of Bone

    From Model to Patient
    • 1st Edition
    • Luis Cardoso + 2 more
    • English
    Biomechanics and Mechanobiology of Bone: From Model to Patient provides readers with a comprehensive overview of the modelling and assessment of bone biomechanics. It addresses topics such as biosubstitutes and bone implants from the point of view of design, properties, computational modeling, and choice of biomaterials. It concentrates on the biomechanics and mechanobiology modeling approaches of bone, including biological models, multiphysical approaches, surface and volumetric growth models, and bone fluid flow models. This is augmented by case studies and examples of models for computer-aided diagnosis, treatment, and monitoring of bone diseases. Readers are introduced to bone physiology, adaptation, and disease, including cellular aspects at the root of bone mechanotransduction and leading to bone growth and remodeling, and management of diseases. Chapters also cover the mechanical, multiphysical multiscale properties of bone and constitutive laws including bone viscoelasticity, poroelasticity, bone damage, fatigue and fracture, as well as measurement techniques of bone properties.

  • Cutting-Edge Technology for Plant Metabolite Profiling in Drug Discovery and Quality Control

    • 1st Edition
    • Ramesh Kumar Ahirwar + 4 more
    • English
    Cutting-Edge Technology for Plant Metabolite Profiling in Drug Discovery and Quality Control offers a comprehensive exploration of advanced methods in plant metabolomics, along with their integration in industrial applications across various sectors. The book delves into a range of methodologies, including metabolic engineering strategies, metabolite imaging techniques, nuclear magnetic resonance (NMR) for plant metabolite analysis, microfluidics for metabolite profiling, computational methods, and bioinformatics tools. It also explores plant metabolomics for crop improvement, pharmaceutical development, archaeological examinations, cosmetic formulations, and food quality, with case studies featured throughout the book to showcase real-world applications and scenarios. As the demand for natural products and plant-derived therapeutics continues to rise, there is a need for reliable and effective methods to identify, quantify, and optimize the bioactive compounds present in plants. This book provides a comprehensive guide to the latest advances in this field while also delivering a multidisciplinary overview of the wide-ranging impact plant metabolites have across a variety of applications. Researchers working with plant metabolites across molecular and cellular biology, pharmaceutical science, biotechnology, biochemistry and plant science will benefit from this book. Additionally, it will be of interest to specialists working across relevant industries, such as pharmaceuticals, nutraceuticals, cosmetics and agriculture.

  • AI in Breast Cancer Stem Cells and Proteomics

    Precision Oncology Perspectives
    • 1st Edition
    • Manzoor Ahmad Mir + 1 more
    • English
    AI in Breast Cancer Stem Cells and Proteomics: Precision Oncology Perspectives explores the intersection of artificial intelligence, cancer stem cell biology, and proteomics to address the persistent challenges of relapse, metastasis, and therapy resistance in breast cancer. This book provides a translational framework for precision oncology through advanced computational and molecular approaches. It gives insight into the biology of breast cancer stem cells (BCSCs), their heterogeneity, and the role of proteomics in identifying biomarkers and therapeutic targets. The integration of AI enables predictive modeling, drug resistance profiling, and multi-omics data analysis, offering novel insights into personalized treatment strategies. Academics benefit from a comprehensive, interdisciplinary resource that bridges cancer biology, bioinformatics, and clinical applications.The book equips researchers, clinicians, and students with case studies, algorithmic tools, and practical workflows to translate proteomic data into actionable medical interventions.

  • Antimicrobial Peptides

    From Science to Applications
    • 1st Edition
    • Anil Kumar Chhillar + 4 more
    • English
    Antimicrobial Peptides: From Science to Applications provides comprehensive coverage on the biology, diversity, and mechanisms of action associated with antimicrobial peptides (AMPs). The book aims to equip readers with the knowledge required to understand, harness, and optimize these molecules for development and application across various sectors. Sections overview the biology and diversity of antimicrobial peptides, cover their molecular structure and function, and delve into their unique mechanisms of action and evolutionary significance in nature. Subsequent chapters go on to explore the utilization of AMPs in medicine, agriculture, the environment, and biotechnology.Culmin... in discussions on future trends, regulatory considerations, and strategies to overcome challenges, this book is an informative reference for researchers, scientists, graduate students, and industry professionals engaged in the study and development of antimicrobial peptides as a potential solution to address pressing challenges such as antibiotic resistance, food security, and environmental sustainability.

  • Modern fMRI

    Practical Lessons and Insights
    • 1st Edition
    • Andrew Jahn
    • English
    The field of neuroimaging with functional magnetic resonance imaging (fMRI) is developing at a rapid pace, with a seemingly endless number of software packages, statistical methods, and different ways to organize and analyze neuroimaging data. Among such a wide variety of options, and with so many seemingly conflicting pieces of advice on the “correct” way of analyzing neuroimaging data, knowing what decisions to make is a difficult task. Modern fMRI: Practical Lessons and Insights provides an up-to-date, holistic overview of the field of fMRI, familiarizing the reader with the latest trends in neuroimaging, such as standardized data organization and preprocessing, advances in functional connectivity and machine learning, and current guidelines in data and code sharing. This includes advice about best practices in preprocessing, statistical modeling, QA checks, and some of the latest tools and concepts to be familiar with, including fMRIPrep, OpenNeuro.org, Open Science practices, and Jupyter notebooks

  • Artificial Intelligence-Driven Metaverse Integration in Smart Healthcare

    Advancing Personalized and Predictive Medical Capabilities
    • 1st Edition
    • Joseph Bamidele Awotunde + 3 more
    • English
    Artificial Intelligence-Driven Metaverse Integration in Smart Healthcare: Advancing Personalized and Predictive Medical Capabilities offers a comprehensive exploration of cutting-edge technologies and their transformative potential in healthcare. The book delves into the application of artificial intelligence (AI) in the healthcare sector, examining machine learning algorithms, natural language processing, and computer vision to enhance healthcare delivery. It also introduces the metaverse, an immersive virtual environment, and explores its integration into medical practices, patient engagement, and health-related experiences. This is an invaluable resource for researchers and practitioners in biomedical fields, health informatics, and personalized and predictive medical systems.In 26 chapters, the book discusses how the convergence of AI and the metaverse contributes to the development of smart healthcare systems that are more efficient, accessible, and personalized. It highlights AI's role in customizing medical treatments, diagnostics, and patient care, leading to more effective healthcare experiences. Additionally, it explores predictive analytics and modeling using AI to prevent diseases, optimize treatments, and improve healthcare outcomes. Providing insights into the current state of AI in healthcare and the potential of metaverse integration, the book includes case studies, practical applications, and future perspectives.

  • Cardiometabolic Dynamics

    A Deep Dive into Health and Disease
    • 1st Edition
    • Yihua Bei + 1 more
    • English
    Cardiometabolic Dynamics: A Deep Dive into Health and Disease explores the intricate relationship between metabolic health and cardiovascular diseases, illuminating how cellular and molecular mechanisms contribute to metabolic dysregulation. The book delves into the ways metabolic pathologies act as precursors to cardiovascular conditions, including hypertension, atherosclerosis, cardiomyopathy, and heart failure. With a focus on healthy cardiometabolic dynamics, it underscores the crucial role they play in sustaining cardiovascular wellness, offering a comprehensive perspective on the intersection of metabolism and heart health.The book further examines the influence of lifestyle factors, such as diet and exercise on cardiovascular metabolism and highlights emerging technologies like omics, genetic engineering, and wearable devices to advance research, diagnosis, and treatment.

  • Advances in Diffusion Magnetic Resonance Imaging for Neurodegenerative Diseases Research

    • 1st Edition
    • Frederic Sampedro
    • English
    Advances in Diffusion Magnetic Resonance Imaging for Neurodegenerative Diseases Research covers how diffusion MRI has contributed to our understanding of common neurodegenerative diseases, bridging common microstructural changes across symptoms and disorders. Sections cover the technical basis of diffusion MRI, focusing on the interpretation of its imaging-derived metrics in terms of neuronal damage. Subsequent chapters are organized by disease, taking an in-depth look at how the use of diffusion MRI has contributed to recent understanding, and how it has motivated potential new therapeutic structures for Alzheimer’s disease, frontotemporal dementia, primary aggressive aphasia, Parkinson’s disease, progressive supranuclear palsy, Huntington’s disease, and more.The book concludes with implications for future research, making it a must-have reference for researchers and clinicians interested in the field of neuroimaging for neurodegenerative disorders.

  • Mesenchymal Stem Cells and Extracellular Vesicles as Next-Generation Therapeutics

    Basic Concepts, Clinical Applications, and Cross-Disciplinary Innovations
    • 1st Edition
    • Naresh Kasoju + 1 more
    • English
    Mesenchymal Stem Cells and Extracellular Vesicles as Next-Generation Therapeutics: Basic Concepts, Clinical Applications, and Cross-Disciplinary Innovations provides a comprehensive exploration of the groundbreaking roles stem cells and extracellular vesicles (EVs) play in regenerative medicine. The book examines the fundamental biology of stem cells and EVs, their therapeutic applications across tissues - including skin, neural, cardiac, ocular, and more and the innovative, interdisciplinary approaches shaping the future of healthcare. Sections cover Basic and Emerging Concepts, Therapeutic Applications and Disease Focus, and Cross-disciplinary Innovations and Future Directions the field will encounter in this rapidly growing branch of medicine.Written by experts in the field for researchers and academics engaged in regenerative medicine, stem cell biology, and biomedical engineering, this book will be of interest to healthcare professionals such as physicians, surgeons, and specialists interested in tissue repair and regeneration.

  • Therapeutic Potentials of Tenofovir Alafenamide in Hepatitis B

    • 1st Edition
    • Lung-Yi Loey Mak + 1 more
    • English
    Therapeutic Potentials of Tenofovir Alafenamide in Hepatitis B offers a comprehensive examination of the therapeutic potentials of Tenofovir Alafenamide (TAF) in hepatitis B, providing a succinct and up-to-date summary of all relevant evidence for this first-line oral antiviral agent. The text delves into key topics such as the pharmacological profile of TAF, its comparative efficacy against traditional antiviral agents, safety and tolerability, and the impact of TAF on drug resistance. Additionally, it explores the use of TAF in special populations, including pediatrics, the elderly, and individuals with renal impairment, as well as future directions in hepatitis B treatment strategies.Readers will discover the diverse potential applications of TAF in chronic hepatitis B, informed by valuable lessons learned from HIV treatment while also gaining insights into future therapeutic possibilities. Authored by leading experts in the field, each chapter presents focused and insightful perspectives, making this book an indispensable resource for practitioners and researchers alike. Serving as a critical resource for physicians, researchers, pharmacologists, and biomedical scientists, this book highlights the core knowledge necessary for understanding TAF and its clinical applications.

  • Tumor Microenviroment

    • 1st Edition
    • Ranjita Shegokar + 1 more
    • English
    Tumor Microenvironment provides an in-depth exploration of the intricate relationships between various cancers and their respective tumor microenvironments. Each chapter focuses on a specific type of cancer, detailing the unique characteristics of its microenvironment, including the roles of immune cells, stromal components, and extracellular matrix. The book highlights advancements in research, diagnostic techniques, and therapeutic strategies aimed at targeting the tumor microenvironment, offering valuable insights into potential future directions in cancer treatment. By presenting cutting-edge information and real-world applications, this book helps readers understand cancer biology while also fostering innovative approaches to research and clinical practice that contribute to improved patient outcomes.

  • Proteostasis and Cancer

    • 1st Edition
    • Buddhi Prakash Jain
    • English
    Proteostasis and Cancer explores the intricate mechanisms of protein homeostasis and their critical roles in cancer progression and therapeutics. The book delves into the mechanisms that control proteins inside the cell to preserve the health of the cellular proteome and the organism itself. It covers key topics such as post-translational modifications, protein folding, proteolysis, and the unfolded protein response (UPR), with a specific focus on their roles in cancer. Detailed discussions on molecular chaperones, the ubiquitin-proteasome system, and autophagy pathways offer valuable insights into how these processes contribute to cancer progression and how they can be targeted for therapeutic interventions.With clear explanations and well-labeled diagrams, the book makes complex concepts accessible to students and researchers alike. It also addresses the clinical implications of proteostasis in cancer, providing a foundation for developing innovative, therapeutic strategies. The book's multidisciplinary approach, combining insights from biochemistry, cancer biology, and medical sciences make it an essential resource for anyone seeking to understand the role of proteostasis in cancer.

  • Nanomedicine in Oncology

    Unveiling Materials, Diagnostics, and Clinical Implications
    • 1st Edition
    • Ajay Kumar + 1 more
    • English
    Nanomedicine in Oncology: Unveiling Materials, Diagnostics, and Clinical Implications is a comprehensive and insightful exploration into the intersection of nanotechnology and cancer treatment. The book provides an in-depth look at the historical foundations, current advancements, and future possibilities, particularly as they apply to oncology. Sections cover both the translation of nanomedicine research into clinical practice and explore various therapeutic applications, including nanoparticle-based chemotherapy, immunotherapy, photothermal and photodynamic therapy, and gene therapy utilizing nanocarriers. Finally, the book provides concluding remarks and an outlook on continued growth and potential in oncology, summarizing key insights and looking forward to future advancements.The book offers valuable perspectives for research and clinical application, fostering a comprehensive understanding of nanomedicine's impact on cancer treatment. It's insights and knowledge make it a globally relevant and impactful resource in the domain of nanomedicine in oncology.

  • ​​Abdominal Pain

    Essentials of Pathophysiology and Treatment
    • 1st Edition
    • Jakub Fichna
    • English
    Abdominal Pain: Essentials of Pathophysiology Treatment is the most up-to-date and comprehensive resource on abdominal pain. The book highlights new biomarkers, targets, and diagnostic techniques that are shaping the future of abdominal pain management, ensuring readers absorb the latest trends in diagnosis and treatment. By covering abdominal pain in the context of various specialties, it ensures a multidisciplinary understanding of these conditions for developing effective treatment strategies and improving patient outcomes. This first of its kind resource focuses on abdominal pain across numerous specialties, eliminating the need to search for information from innumerable sources.It is designed for researchers, clinicians, and students, providing an unparalleled depth of knowledge and insights into the diagnosis and treatment of abdominal pain. Expert contributors, selected for their specialized knowledge, bring the latest publications, advances, and cutting-edge research to ensure the most current information available. This innovative approach compiles diverse aspects of abdominal pain, offering insights into pathophysiology, molecular pathways, and potential cross-talks. Whether you are a seasoned clinician, a researcher, or a medical student, this guide will provide you with the most current and comprehensive information available, helping you stay at the forefront of abdominal pain diagnosis and treatment.

  • Stem Cells Simplified

    A Complete Guide to the Science and Applications
    • 1st Edition
    • Mahmood S. Choudhery + 2 more
    • English
    Stem Cells Simplified: A Complete Guide to the Science and Applications focuses on specific aspects of stem cells, making it a complete resource, from basic concepts to the latest applications. The book's chapters progress from basic knowledge to practical applications and techniques, concluding with ethical considerations and future directions in the field. Written for students and researchers in stem cell biology, regenerative medicine, and related fields, this book will also be relevant to medical professionals and clinicians interested in stem cell therapies and industry professionals working on stem cell-based products and technologies.

  • Type 2 Diabetes Mellitus

    Exploring Immunogenetic Pathways
    • 1st Edition
    • Haamid Bashir + 2 more
    • English
    Type 2 Diabetes Mellitus: Exploring Immunogenetic Pathways is a novel reference to gain a deep understanding of the genetic underpinnings and immune system dynamics in Type 2 Diabetes Mellitus (T2DM). It addresses a fundamental gap in the current literature by synthesizing complex information into accessible chapters serving as a roadmap for those needing to navigate the intricate landscape of immunogenetics. It equips readers with the tools to comprehend the underlying mechanisms, discover potential therapeutic strategies, and contribute to the ongoing dialogue in this rapidly advancing field. Real-world case studies and clinical scenarios are throughout the book to illustrate the practical applications of immunogenetics in diagnosing, treating, and managing Type 2 Diabetes Mellitus to help bridge the gap between theory and practice and enhance the relevance of the content for healthcare professionals. The book Explore the integration of multi-omics approaches, including genomics, transcriptomics, proteomics, and metabolomics, to provide a comprehensive understanding of the complex interactions between genetic and immunological factors in Type 2 Diabetes Mellitus. This holistic approach can offer insights into novel biomarkers and therapeutic targets. In addition, discussions on the ethical, legal, and social implications of immunogenetics research in Type 2 Diabetes Mellitus, such as genetic privacy, informed consent, and equity in healthcare access. Addressing these considerations is essential for promoting responsible research practices and ensuring equitable healthcare outcomes. The book is essential for seasoned researchers in T2DM, healthcare professionals, or a student entering the field; this book offers invaluable insights into the future of T2DM research and treatment.

  • Innovation in Health Informatics

    A Smart Healthcare Primer
    • 2nd Edition
    • Miltiadis Lytras + 2 more
    • English
    Innovation in Health Informatics: Driving Value-Based Healthcare through Economic Efficiency, Second Edition addresses rapid advancements in health informatics by integrating the latest technologies and methodologies. The revised edition includes new chapters on Digital Twins, Blockchain, AI Applications for Personalized Medicine, and Health Analytics Dashboards, enriching foundational topics. The book delves into the economic implications and practical applications of these technologies, offering evidence-based strategies for their integration into healthcare systems. For the academic audience, this book bridges the gap between theory and practice, featuring practical case studies, end-of-chapter summaries, and interactive components like QR codes linking to online resources and simulation videos.The primary goals of this revision are to update the book with the latest technological advancements, expand the scope to include emerging topics, and enhance existing chapters, ensuring it remains a comprehensive resource for professionals and students. This updated edition equips readers with up-to-date knowledge and tools to navigate and innovate within the evolving landscape of health informatics.

  • Unlocking Sirtuins

    Cellular Biology to Translational Research
    • 1st Edition
    • Pranav Kumar Prabhakar + 1 more
    • English
    Unlocking Sirtuins: Cellular Biology to Translational Research explores the intricate roles of sirtuins, from basic principles to clinical significance. The book is organized into six parts, covering foundational concepts, roles in aging and metabolism, disease pathology, therapeutic strategies, future research directions, and potential challenges. Topics include the structure and evolution of sirtuins, their mechanisms of action, and their impact on neurodegenerative diseases, cardiovascular health, and cancer. The book also features detailed chapters on sirtuin modulators, drug discovery, the latest technologies and tools in the field, emerging trends, and the challenges, ethical considerations and future directions of sirtuin-targeted therapies.The book's content is complemented by case studies, clinical insights, and step-by-step procedures, offering a comprehensive and practical exploration of the subject. Users will find an in-depth overview of sirtuin biology, bridging fundamental science with clinical applications. This comprehensive resource will serve as an essential resource for researchers, clinicians, and advanced students working across cellular and molecular biology, biochemistry, pharmacology, aging, metabolic disorders, translational medicine, and related fields.

  • Autophagy – Part A

    • 1st Edition
    • Volume 403
    • English
    Autophagy – Part A, Volume 403 explores the fundamental biological process of autophagy. Beginning with the historical discovery and molecular mechanisms of autophagy, the book delves into its regulation, physiological roles, and significance in maintaining cellular homeostasis. Chapters in this new release include Ciliophagy: Maintaining Primary Cilium Homeostasis to Prevent Cilium-Related Diseases, Unraveling the interplay of glycolysis, lactylation, and autophagy, Autophagy and Type 2 Diabetes: Bridging the Gap in Metabolic Health, Autophagy in Cancer Cachexia: From Mechanisms to Therapeutic Opportunities, Glycophagy: A Selective Autophagy Pathway for Glycogen Degradation, Role of Autophagy in Adipose Tissue: Implications for Metabolic Health, and more.

  • Cell Death Part C

    • 1st Edition
    • Volume 208
    • English
    Cell Death: Part C, Volume 208 continues the comprehensive exploration of cellular mechanisms governing the fate of cells in health and disease. This volume delves deep into the molecular pathways, regulatory networks, and biological consequences of various cell death modalities, including apoptosis, necrosis, autophagy, ferroptosis, pyroptosis, and other emerging forms.

  • Nanotechnology in Skin Cancer Management

    • 1st Edition
    • Harpreet Singh + 1 more
    • English
    Nanotechnology in Skin Cancer Management presents groundbreaking advances in nanotechnology that are reshaping the fields of dermatology and oncology. This comprehensive resource provides a deep dive into the latest research, state-of-the-art techniques, and practical applications of nanotechnology in the treatment of skin cancer. It serves as a comprehensive guide for those interested in unlocking the potential of nanotechnology for enhancing skin cancer management by consolidating essential information, making it an invaluable resource for understanding and harnessing the power of nanotechnology in this context.By offering an extensive overview of cutting-edge research, advanced technologies, and real-world clinical applications, this book demonstrates how nanotechnology can be designed to potentially revolutionize skin cancer management.

  • Encyclopedia of Animal Behavior

    • 3rd Edition
    • Benjamin Oldroyd
    • English
    Encyclopedia of Animal Behavior, Third Edition, Four Volume Set is a unique curated collection of punchy essays on all aspects of animal behavior, written by experts and carefully edited for readability and accessibility. Animal behavior is usually defined as what animals do, i.e. their movements. We can ask how they move, (i.e. the physiological and neurological causes of movement) and why they move. To answer this latter question, behavioralists generally turn to evolutionary explanations. The Encyclopedia gives equal weight to these ‘how’ (proximate) and `why` (ultimate) explanations of animal behavior. The third edition updates and expands the previous version to cover all substantive topics in the field. Animal behavior is one of the largest subdisciplines in biology. Therefore, chapters focus on broad concepts and avoid becoming entrapped in taxon-specific detail. To illustrate this, one could consider the topic ‘cooperative hunting’. One way to cover this topic would be to have individual chapters on hunting in lions, mongoose, African wild dogs, army ants, dolphins etc. But it would serve the reader much better if a comparative approach was taken to see if there are commonalities across taxa. For example, is communication necessary for cooperative hunting? Is there any evidence of planning or is every hunt opportunistic? This comparative approach requires authors to provide a synthesis, pushing beyond specific taxa of expertise, but helps readers making useful connections. This is a fundamental feature of this work. This edition retains chapters on the historical development of the field, which is important to our understanding of where the discipline sits today, but similarly the work is forward leaning, including the authors` perspective of where their discipline is headed. Structured chapters and cross-references help readers following their interests with ease. Like a bird field guide, this encyclopedia is an entrée to deeper knowledge. Readers of the encyclopedia are encouraged to explore beyond individual chapters via links to related ones, key reviews and relevant online material.

  • The Exposome in Cancer Disparities

    Influence of Environmental and Infectious Factors in LMICs
    • 1st Edition
    • Zodwa Dlamini
    • English
    The Exposome in Cancer Disparities: Influence of Environmental and Infectious Factors in LMICs examines how environmental and infectious factors drive cancer inequities in low- and middle-income countries (LMICs). The book introduces the exposome as a comprehensive framework to understand complex risk factors, such as environmental toxins, climate change, and infectious agents like HPV and HIV. The book combines scientific insights, real-world case studies, and practical strategies from international experts, highlighting region-specific contributors to cancer disparities. Structured into thematic sections, it offers a holistic view of the challenges faced by LMICs and provides actionable, evidence-based solutions tailored to resource-limited settings.The work emphasizes the importance of multidisciplinary approaches and international collaboration to develop effective prevention and policy strategies. It will benefit researchers, policymakers, and healthcare professionals by deepening understanding of cancer risk factors, fostering global cooperation and guiding targeted interventions to reduce health inequities and improve outcomes worldwide.

  • Nanobiotechnology for Clinical Adoptability and Application

    • 1st Edition
    • Pawan Kumar Maurya + 3 more
    • English
    Nanobiotechnology for Clinical Adoptability and Application offers an overview of bioanalytical methods and medical biotechnological applications in diagnostic and therapeutics. The book discusses modern concepts and bioanalytical methodologies in nanoscience and nanobiotechnology and their integration in real-time point-of-care applications which has emerged as a significant area of industrial research. It explores medical diagnostic use of different imaging and biosensing technologies, including biochemical methods, electrochemical sensors to detect infectious diseases, and microfluidics-based bioanalytical systems. It also covers biotechnological approaches to experimental therapeutics and theranostics.Ethical and regulatory considerations in biomedicine and medical diagnostics round out the coverage making this book a valuable resource for researchers, faculty, post-graduate students and professionals in biotechnology, biochemistry, nanotechnology, biomedical engineering, medicine, pharmaceutical sciences, or any related biomedical discipline.

  • Nutritional Epigenomics

    • 2nd Edition
    • Volume 14
    • Bradley S. Ferguson
    • English
    Nutritional Epigenomics, Second Edition, Volume Fourteen in the Translational Epigenetics series, offers a comprehensive overview of nutritional epigenomics as a mode of study, along with nutrition’s role in the epigenomic regulation of disease, health, and developmental processes. Here, an expert team of international contributors introduces readers to nutritional epigenomic regulators of gene expression, our diet’s role in epigenomic regulation of disease and disease inheritance, caloric restriction and exercise as they relate to recent epigenomic findings, and the influence of nutritional epigenomics over circadian rhythms, aging and longevity, and fetal health and development, among other processes.Disease specific chapters address metabolic disease (obesity and diabetes), cancer, and neurodegeneration, among other disorders. Diet-gut microbiome interactions in the epigenomic regulation of disease are also discussed, as is the role of micronutrients and milk miRNAs in epigenetic regulation. Finally, chapter authors examine ongoing discussions of race and ethnicity in the social-epigenomic regulation of health and disease. This new edition has been fully updated to reflect current research in the field.

  • Transposable Elements in Health and Disease

    • 1st Edition
    • Volume 116
    • English
    Transposable Elements in Health and Disease, Volume 116 in the Advances in Genetics series, highlights new advances in the field, with this new volume presenting comprehensive chapters on a variety of timely topics. Specific chapters examine Transposable Elements in Human Cancer: Regulation, Activation, and Genomic Consequences, Retrotransposons as both “architects” and “saboteurs” in the nervous system, Shaping Mammalian Genomes: The Regulation and Co-option of Transposable Elements, Transposable element analysis in -omics data, and Transposable elements in Aging: from biomarkers to effectors.Together, these contributions provide valuable insights into the mechanisms and impacts of transposable element activity, advancing our understanding of their broad significance in genetics, development, health, and disease.

  • Hypercortisolism: Diagnosis and Differential Diagnosis

    • 1st Edition
    • Volume 132
    • English
    Hypercortisolism: Diagnosis and Differential Diagnosis, Volume 132 presents a comprehensive series of chapters focused on the various aspects of endogenous hypercortisolism as contributed by an international team of specialists in endocrinology. Chapters in this new release include Cushing´s syndrome: Clinical presentation and associated comorbidities, Biochemical diagnosis of hypercortisolism: when and how?, ACTH independent Cushing syndrome: diagnosis and etiology, Bilateral macronodular and micronodular hyperplasia: biochemical, radiological and genetic diagnosis, Differential diagnosis between endogenous Cushing´s syndrome and pseudoCushing, and much more.Additional chapters delve into Differential diagnosis of ACTH dependent Cushing´s syndrome: hormonal and radiological studies, Ectopic Cushing´s syndrome: clinical presentation and diagnosis, Cyclic Cushing´s syndrome, Mild autonomous cortisol secretion: diagnosis, Cushing´s syndrome and pregnancy: clinical presentation and diagnosis, Molecular profile of Cushing´s syndrome, Cardiometabolic comorbidities in overt Cushing´s syndrome, and New tools for the diagnosis of hypercortisolism.

  • Bioorthogonal Labeling

    • 1st Edition
    • Volume 731
    • English
    Biorthogonal Tagging, Volume 731 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters such as Staudinger Ligations and Related Reactions: Scope and Applications in Chemical Biology, Strain-Promoted Bioorthogonal Cycloadditions to Investigate Sialyltransferases Promiscuity Towards Unnatural Sialic Acids, Practical Guidelines for the Bioorthogonal AMI–Isonitrile Ligation, Nitrones and Other Dipoles in Bioorthogonal Chemistry Applications, 1,2-Aminothiol-Speci... Conjugation for Dual-Color Fluorescent Labeling via Ultrafast TAMMs, Genetic Incorporation of Bicyclononyne for Cell-Surface Protein Labeling via Tetrazine Ligation, and much more.Additional chapters cover Genetic Code Expansion for Single Noncanonical Amino Acid Incorporation into SARS-CoV-2 Omicron Spike on Amber-Free Lentiviral Particles, Bioorthogonal Click-Chemistry Labeling and Visualization of Dual Noncanonical Amino Acid–Incorporated HIV-1 Env on Intact Virions, Studying Bacterial Glycans with Azidosugars and Bioorthogonal Chemistry, Bioorthogonal Tagging of DNA and RNA, Efficient Labeling of Pathogenic Fungal Chitin with Bioorthogonal Probes, and many more timely topics.

  • Cellular Communication in Mammalian Germ-line Development

    • 1st Edition
    • Volume 169
    • English
    Cellular Communication in Development, Volume 169 provides a comprehensive overview of the intricate signaling pathways and molecular mechanisms that govern how cells communicate during the development of multicellular organisms. This volume explores the essential roles of cell-to-cell communication in processes such as embryogenesis, tissue patterning, organ formation, and differentiation. Specific chapters include Specification of pgcs, Establishing and maintaining gonadal cell fate, Role of retinoic acid in meiosis, Assembly of primordial follicles, Activation of primordial follicles, Mechanisms of germ-soma communication during follicular growth, Somatic regulation of oocyte meiotic arrest and resumption, Ovarian stroma/function/role in aging, and much more.Additional sections explore New approaches to supporting follicle growth/ovarian function in vitro, Cancer therapy - effects on survival/development of oocyte/follicle, Female germ cells from somatic cells, Spermatogenic stem cell niche, Role of macrophages in testis function, Male germ cells from somatic cells, and more.

  • Flavonoids Against Cancer Hallmarks

    • 1st Edition
    • Dharambir Kashyap + 1 more
    • English
    Flavonoids Against Cancer Hallmarks provides an in-depth exploration of the anti-cancer potential of flavonoids and their ability to target key cancer hallmarks. The book encompasses a thorough analysis of flavonoids' sources, bioavailability, metabolic disposition, long-term safety, and adverse effects. It highlights the mechanisms through which flavonoids inhibit cancer growth and proliferation, focusing on their immunomodulatory, anti-angiogenic, anti-metastatic, and cell cycle inhibitory effects. Designed for oncology specialists, pharmacology and pharmacy students, cancer research scholars, and pharmaceutical industry researchers, this comprehensive guide also reviews recent cancer epidemiology and updates on existing therapeutic strategies.By detailing how flavonoids counteract cancer stemness and influence immune responses, this book offers innovative insights into utilizing plant-derived compounds for cancer treatment. It stands out by providing a detailed overview of flavonoids' cellular and molecular mechanisms while also evaluating the pros and cons of current therapeutic options, making it essential reading for a global audience.

  • Autophagy – Part C

    • 1st Edition
    • Volume 406
    • English
    Autophagy, Part C, Volume 406 dives cellular housekeeping, weaving together the mechanistic precision of modern biology with the larger questions of health, aging, and resilience. Building on the foundations laid in Parts A and B, this book takes the reader from the microscopic machinery inside a single cell to the sweeping implications for organisms, ecosystems, and medicine. Chapters cover Lysosomal Function and Homeostasis: From Cellular Adaptation to Disease Pathogenesis, Autophagy Meets Plant Virology: From Molecular Crosstalk to Outstanding Challenges, Impact of mitophagy on obesity-affected tissues, Autophagy in Endothelial Cells: a gatekeeper of immune cell trafficking and function, and much more.Additional sections cover Viral Trafficking: The Role of Autophagy in the Release of Virus-Loaded Extracellular Vesicles and Sex matters in macroautophagy: sex-driven differences in autophagic function in aging and aging related-diseases.

  • Current Approaches to Cryo-electron Microscopy

    • 1st Edition
    • Volume 223
    • English
    Current Approaches to Cryo-electron Microscopy, Volume 223 provides a comprehensive overview of the field, tracing its evolution from early structural studies to modern pipelines powered by deep-learning algorithms for helical reconstruction. The book addresses the persistent bottleneck of sample preparation, detailing the physical challenges of fibril clumping and interfacial adsorption, alongside emerging solutions to these problems. Chapters in this new release include Advancing biological understanding of the poxvirus scaffold through breakthroughs in cryo-electron microscopy, Pursuing the physics of cryoEM image formation, AI Tools for Cryo-EM: Protein Particle Picking, Density Map Enhancement, and Atomic Model Building, and much more.Additional chapters cover Cryo-EM of Amyloid Fibrils: Advances, Challenges, and Translational Applications, Computational Approaches for Protein Complex Modeling for Intermediate Resolution Cryo-EM Maps, Calcium-sensing receptor, involved in the oral perception of the kokumi substances, Insights into the Structure and Diversity of the Bacterial Flagellum from cryo-EM studies, Overview and future potential in structural studies of bacteriophages by cryo-electron microscopy, and more.

  • Next-Generation Onco-Therapeutics

    • 1st Edition
    • Awanish Kumar + 1 more
    • English
    Next-Generation Onco-Therapeutics explores the latest advancements in cancer treatment, focusing on personalized medicine and innovative therapeutic strategies. The book serves as a comprehensive resource for understanding how emerging technologies can reshape oncological care, providing insights into effective and compassionate patient management. Content explores cutting-edge developments in cancer therapies, featuring clinical examples and case studies that illustrate the practical application of new treatment modalities. It emphasizes the importance of integrative approaches that address the diverse needs of cancer patients, ensuring that healthcare professionals are equipped with the most current information in this rapidly evolving field. This book also addresses the urgent need for updated resources in oncological therapeutics, bridging the gap between traditional practices and modern innovations. By synthesizing diverse perspectives and evidence-based insights, it empowers healthcare providers, researchers, and policymakers to enhance treatment outcomes and improve patient well-being in the era of personalized medicine.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 133
    • English
    Advances in Clinical Chemistry, Volume 133 in this ongoing series, examines physiologic and pathophysiologic biochemistry and their impacts on Clinical Chemistry testing and design. Molecular mechanisms of disease processes are highlighted in the context of traditional, current, and emerging technologies, and advances in the development of improved diagnostic and predictive biomarkers are examined, especially those targeting early and emerging diseases. Specific chapters in this new release include Drug Induced Renal Injury (DIRI) Biomarkers, Unveiling tobacco markers in exhaled breath, Advances in small extracellular vesicle analysis, Piezoelectric Sensors in Point-of-Care Testing, Mitochondrial myopathy biomarkers, and Hormonal and Metabolic Biomarkers in Long COVID.

  • Epigenetic Therapy by Phytochemicals in Lung Cancer

    Mechanisms, Therapeutic Potential, and Clinical Implications
    • 1st Edition
    • Umesh Kumar + 3 more
    • English
    Epigenetic Therapy by Phytochemicals in Lung Cancer provides a comprehensive exploration of the intersection between cancer epigenetics and phytotherapy, focusing on lung cancer. The book emphasizes the role of epigenetic alterations in cancer progression and presents phytochemicals as promising agents capable of reversing these changes, thereby offering innovative therapeutic strategies. The content examines the mechanisms by which epigenetic modifications, such as DNA methylation and histone modification, contribute to lung cancer. It details specific phytochemicals—like curcumin, resveratrol, and quercetin—and their potential to modulate these pathways, while discussing clinical applications, challenges, and future research directions. For academics, this book equips researchers and healthcare professionals with evidence-based insights into alternative cancer therapies, enhancing understanding of multi-targeted approaches. It serves as a valuable reference for teaching and further research, promoting a more inclusive perspective in cancer care and addressing disparities in treatment access and efficacy.

  • Yoga and Prevention of Type 2 Diabetes

    An Integrated Approach to Wellness
    • 1st Edition
    • S.V. Madhu
    • English
    Yoga and Prevention of Type 2 Diabetes: An Integrated Approach to Wellness is a unique reference to approaching yoga, its principles, and how its various practices contribute to overall health and wellness and to understanding the scientific evidence and impact of yoga on glycemic control, insulin sensitivity, and stress reduction. The book lays the foundation to understanding the pathophysiology, epidemiology, and risk factors associated with type 2 diabetes while exploring the physiological and biochemical pathways by which yoga influences glucose metabolism and mitigates diabetes risk factors.Collectively... the book's chapters equip readers with a thorough understanding of Type 2 diabetes and the multifaceted role of yoga in its prevention and management. By combining theoretical knowledge with practical applications, this work will empower individuals and healthcare providers to take proactive steps toward better metabolic health through yoga.

  • Advances in Microbial Physiology

    • 1st Edition
    • Volume 88
    • English
    Advances in Microbial Physiology, Volume 88 explores the latest research and developments in microbial physiology, providing a comprehensive overview on how microorganisms function, adapt, and interact with their environments. This volume brings together leading experts to discuss fundamental processes such as metabolism, growth, gene regulation, signal transduction, stress responses, and cellular differentiation in bacteria, archaea, and fungi. Chapters cover Steroids as Antibacterials, From Feeding Cell to Fruiting Body: Multidrug Transport in the Life cycle of Dictyostelium discoideum, Evolution of xenobiotic catabolism, Glycyl-radical enzymes, How anaerobes cope with oxygen, and Extracellular Electron Transfer: From Early Life to Modern Biogeochemistry and Applications.

  • Human Microbiota for Skincare

    Sustainable, Innovative, and Personalized Skincare with Skin Microbiota
    • 1st Edition
    • Nar Singh Chauhan + 2 more
    • English
    Human Microbiota for Skincare: Sustainable, Innovative, and Personalized Skin Care with Skin Microbiota explores the latest trends, innovations, and emerging research in microbiota-based skincare, positioning readers at the forefront of skincare advancements. It presents a global overview of current and future research, providing a comprehensive understanding of the skin microbiome and its potential applications in skincare. The book offers detailed insights into the interplay between the skin microbiome and human health, with chapters covering essential topics such as Personalized Skincare, Macroecological Dynamics of Skin Microbiota, Host-Microbe Interplay During Skin Diseases and Aging, Microbiome-Based Skin Care Formulations, and Ethical Regulations of Skin Therapies.This book consolidates datasets and real-life case studies, offering practical advice on incorporating microbiota-based products into daily routines and exploring future trends in microbiota-based skincare. Whether you are a scientist, researcher, or clinician, this book is an essential resource. It provides authoritative advice from experts in microbiology, dermatology, and biochemistry, facilitating multidisciplinary research and enhancing your ability to treat patients.

  • AI-enabled Sustainable Healthcare

    Demystifying Secure Quantum Blockchain
    • 1st Edition
    • M. Nivaashini + 4 more
    • English
    AI-Enabled Sustainable Healthcare: Demystifying Secure Quantum Blockchain explores the convergence of quantum computing, blockchain technology, and artificial intelligence in the context of healthcare. In today's rapidly evolving technological landscape, traditional healthcare systems face challenges related to data security, interoperability, and the efficient utilization of patient information. The emergence of quantum computing, blockchain, and AI presents unprecedented opportunities to overcome these challenges and revolutionize healthcare delivery. This book provides a clear and accessible overview of these complex technologies and their potential applications in healthcare. By demystifying these concepts and illustrating their real-world implications, the book equips readers with the knowledge and insights needed to navigate the intersection of technology and healthcare effectively. Furthermore, as the demand for secure, transparent, and sustainable healthcare solutions continues to grow, there is an urgent need for informed discussions and innovative approaches in this field.

  • Advances in Biomedical Engineering - Part A

    • 1st Edition
    • Volume 402
    • English
    Advances in Biomedical Engineering, Part A, Volume 402 provides a comprehensive overview of the latest developments, innovations, and research in the rapidly evolving field of biomedical engineering. This book covers a broad spectrum of topics, including medical imaging, biomaterials, tissue engineering, biomechanics, bioinstrumentation, and healthcare technologies. Specific chapters include Advances in biomedical engineering, Recent advances in nanomedicine as drug delivery systems, Advances in Nano biomaterials for Biomedical Engineering, Neurodiagnostic: Advances in diagnostic tools, Advances in Ferroptosis Research and Application, Bioink-based 3D Bioprinting: Paving the Path for Regenerative Medicine, and MRI Acute/Sub-Acute Ischemic Stroke Segmentation with Deep Learning: A Comprehensive Review.

  • Intelligent Cyber-Physical Systems for Sustainable Healthcare

    • 1st Edition
    • Vandana Bajaj + 5 more
    • English
    Intelligent Cyber-Physical Systems for Sustainable Healthcare addresses the integration of emerging technologies like Virtual Reality, Smart Robotics, and Human-Computer Interaction, which are crucial for maximizing digital health's potential. The book includes case studies that highlight challenges faced by medical practitioners and industry professionals, providing valuable insights for designing sustainable iCPS solutions. Aimed at biomedical engineers, researchers, and industry professionals, it offers guidance for developing practical applications in sustainable healthcare. Additionally, shared, cross-disciplinary experiences assist engineers with less clinical expertise in enhancing healthcare applications in the intelligent digital health sector. Overall, case studies illustrate past challenges in the healthcare industry and present effective solutions to overcome them, making the book a comprehensive resource for advancing sustainable healthcare practices.

  • Intelligent Osteogenesis

    How A.I., New Materials, and Manufacturing Technologies Are Reshaping Bone Regeneration
    • 1st Edition
    • Carlo Galli
    • English
    Intelligent Osteogenesis: How A.I., New Materials, and Manufacturing Technologies are Reshaping Bone Regeneration delves into the revolutionary intersection of technology and medicine. The book focuses on how cutting-edge advancements like artificial intelligence, nanotechnology, biotechnology, and material science significantly influence and transform bone regeneration therapies. It aims to shed light on the multifaceted nature of this field, bringing diverse elements together to reveal their collective impact. The book covers the use of A.I. to monitor advancements, the acceleration of research, and the technological influence on the application of bone regenerative techniques.Authored by experts, it serves as a definitive guide for both biomedical researchers and clinical practitioners in dentistry and orthopedics.

  • Computational Approaches to Natural Products Discovery

    • 1st Edition
    • Volume 730
    • English
    Computational Approaches to Natural Products Discovery, Volume 720 provides descriptions of the latest techniques in computational methods for the study of natural products. Techniques covered are related to genome mining, natural product biosynthesis, natural product evolution, and natural product structure. Chapters in this new release cover Prediction of natural product bioactivity from BGC sequence to guide genome mining efforts, Genome mining for resistance genes to identify bioactive natural products with ARTS, Predicting lasso peptide structure with LassoPred, Predicting lanthipeptide structure with Rosetta, Using lsaBGC to investigate BGC Evolution, and an Analysis of BGC evolution with CORASON.

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