
Abdominal Pain
Essentials of Pathophysiology and Treatment
- 1st Edition - April 1, 2026
- Latest edition
- Editor: Jakub Fichna
- Language: English
Epigenetic Regulations in Gastrointestinal Cancers delves into the complex genomic and epigenomic changes that drive the aggressive nature of GI cancers. Synthesizing the latest… Read more

Epigenetic Regulations in Gastrointestinal Cancers delves into the complex genomic and epigenomic changes that drive the aggressive nature of GI cancers. Synthesizing the latest scientific research, it examines how the tumor microenvironment and cellular signaling pathways influence neoplasia. By integrating knowledge across fields and presenting real-world case studies, the book highlights successful treatment strategies informed by epigenetic discoveries. Its multidisciplinary approach aims to bridge the gap between laboratory research and clinical practice, offering a holistic view crucial for advancing therapeutic development and improving outcomes for patients facing GI cancers.
In addition to expert contributions, the book provides readers with an interactive online platform featuring up-to-date resources and insights. It emphasizes the need to keep pace with fast-evolving cancer research and identifies specific epigenetic targets to tackle treatment resistance. By fostering dialogue among researchers and clinicians, the text promotes collaborative, personalized approaches to oncology.
In addition to expert contributions, the book provides readers with an interactive online platform featuring up-to-date resources and insights. It emphasizes the need to keep pace with fast-evolving cancer research and identifies specific epigenetic targets to tackle treatment resistance. By fostering dialogue among researchers and clinicians, the text promotes collaborative, personalized approaches to oncology.
- Provides an in-depth analysis of the various epigenetic changes that contribute to the aggressiveness of gastrointestinal cancers
- Bridges the gap between fundamental research findings and their clinical implications, offering case studies and expert insights that illustrate successful therapeutic strategies
- Emphasizes the importance of multidisciplinary collaboration in cancer research and treatment, presenting contributions from experts across various subfields
Researchers (basic science, clinical) and practicing clinicians
1. Abdominal pain - molecular basis and clinical consequences
2. (working title) Disorders of gut brain interaction (DGBI)
3. Cyclic vomiting syndrome and abdominal pain
4. Hepatobiliary pain
5. Pancreatitis and abdominal pain
6. Pancreatic cancer and its association with abdominal pain
7. Immunotherapy and gastrointestinal-related side effects in patients with cancers
8. Microbiota and pain(working title)
9. (working title) Microbiome modulation to overcome abdominal pain
10. (working title) An update on TRP channels in visceral pain and inflammation
11. Preclinical models of visceral pain
2. (working title) Disorders of gut brain interaction (DGBI)
3. Cyclic vomiting syndrome and abdominal pain
4. Hepatobiliary pain
5. Pancreatitis and abdominal pain
6. Pancreatic cancer and its association with abdominal pain
7. Immunotherapy and gastrointestinal-related side effects in patients with cancers
8. Microbiota and pain(working title)
9. (working title) Microbiome modulation to overcome abdominal pain
10. (working title) An update on TRP channels in visceral pain and inflammation
11. Preclinical models of visceral pain
- Edition: 1
- Latest edition
- Published: April 1, 2026
- Language: English
JF
Jakub Fichna
Dr. Jakub Fichna is a pharmacologist and gastroenterologist, with more than 20 years of experience in the field. He has co-authored more than 350 original and review articles, and several book chapters. Additionally, he has served as editor of several books dedicated to furthering the work of researchers and clinicians. Dr. Fichna is a Fulbright Scholar, and a recipient of the UEG Rising Star Award. He has been the PI in several grants in the area of gastroenterology. Over his distinguished career, he has built a strong network of researchers and fruitful collaborations with clinicians worldwide. His previous works have been cited over 7,237 times.
Affiliations and expertise
Medical University of Lodz, Poland