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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

BooksJournals

    • Genomic Biomarkers for Pharmaceutical Development

      • 1st Edition
      • July 16, 2013
      • Yihong Yao + 2 more
      • English
      • Hardback
        9 7 8 0 1 2 3 9 7 3 3 6 8
      • eBook
        9 7 8 0 1 2 3 9 7 7 9 4 6
      Genomic Biomarkers for Pharmaceutical Development: Advancing Personalized Health Care provides an in-depth review of the state of translational science across all stages of pharmaceutical development with a special focus on personalized health care. This book provides a complete picture of biomarker development and validation in a pharmaceutical setting while addressing the inherent challenges of targeting the appropriate indications, biomarker robustness, regulatory hurdles, commercialization and much more. It features case studies devoted to the applications of pharmacogenomics, toxicogenomics, and other genetic technologies as they support drug discovery and development. With chapters written by international authorities in industry and academia, this work is a truly unique presentation of the thoughts and approaches that lead to the development of personalized medicine. Intended for all those involved in clinical translational research, this book is the ideal resource for scientists searching for the applications, strategies and successful approaches of translational science in pharmaceutical development.

    • Ultrastructure of the Kidney

      • 1st Edition
      • September 17, 2013
      • Albert J. Dalton + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 5 4 2 2 7
      • Hardback
        9 7 8 1 4 8 3 2 3 0 9 7 9
      • eBook
        9 7 8 1 4 8 3 2 6 6 4 7 3
      Ultrastructure in Biological Systems, Volume 2: Ultrastructure of the Kidney provides an overview of the state of knowledge on the ultrastructure of the mammalian kidney. The application of the electron microscope to studies of the kidney resulted in the demonstration of the hitherto undetected early thickening of the basement membrane of glomerular capillaries in glomerulonephritis. Yet many problems remain, particularly in relation to the correlation between function and the ultrastructure of components of the kidney—mesangium, glomerulus, juxtaglomerular apparatus, and the renal tubules. It is only recently that the mesangium has come to be accepted as real, and many questions remain as to the function of its cells. The existence of true membranes between foot processes of the epithelial cells of glomeruli is a newly established fact; but what this has to do with glomerular filtration is not known at present. Granules apparently secretory in nature have been identified in cells of the juxtaglomerular apparatus, but so far their presence has not been correlated with specific functional change. Artifacts introduced at fixation are now known to have considerable relevance in interpreting the ultrastructure of the normal nephron. These are paraphrased views of the contributors to this monograph who, while acquainting the reader with the research being carried on in these areas, have also brought into focus the many problems still awaiting solution.

    • Discovery of Novel Natural Products with Therapeutic Potential

      • 1st Edition
      • October 22, 2013
      • Vincent P. Gullo
      • English
      • eBook
        9 7 8 1 4 8 3 2 9 2 1 3 7
      Although science has discovered effective drugs for many of the diseases that afflict mankind, many human health problems remain untreatable. The search for novel therapeutic agents is always ongoing. This book will describe some of the diverse sourcesof natural products, such as terrestrial and marine environments; and will review how research has increased knowledge of biological systems and human disease, leading to the design of targeted asssays, amenable to high volume screening.

    • Pathobiology of Cell Membranes

      • 1st Edition
      • October 22, 2013
      • Benjamin F. Trump + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 7 0 1 5 0 1 9
      • eBook
        9 7 8 1 4 8 3 2 7 6 1 4 4
      Pathobiology of Cell Membranes, Volume I, represents the first in a multivolume treatise designed for pathologists and cell biologists interested in the role of membrane alterations in disease processes. The treatise will emphasize concepts related to membrane alterations in cell injury as well as methods for elucidating such changes. The book begins with a discussion of the general conceptual aspects of cell injury and some details about the role of membrane alterations in the pathogenesis of both lethal and sublethal cellular reactions. This is followed by separate chapters on applications of circular dichroism to the study of membranes; a cell injury mechanism involving membrane components at the molecular level; and fundamental aspects of cell volume regulation and the modification of this regulation by primary or secondary damage of the cell membrane. Subsequent chapters deal with comparative roles of lysosomal and other membrane damage in cell injury; the role of membrane movements and various types of lysosome formation; toxic effects on mitochondrial membranes; and the concept of a biological membrane in health and disease at the tissue level.

    • Emery and Rimoin's Principles and Practice of Medical Genetics

      • 6th Edition
      • March 20, 2013
      • David L. Rimoin + 2 more
      • English
      • eBook
        9 7 8 0 1 2 3 8 3 8 3 5 3
      For decades, Emery and Rimoin’s Principles and Practice of Medical Genetics has provided the ultimate source for practicing clinicians to learn how the study of genetics can be integrated into practice. With almost 5,000 pages of detailed coverage, this fully online sixth edition of the classic reference adds the latest information on prenatal diagnosis, genetic screening, genetic counseling, and treatment strategies to complete its coverage of the growing field for medical students, residents and physicians involved in the care of patients with genetic conditions. Clinically oriented information is supported by expanded sections on basic principles of genetics, research approaches, and analytics to embrace the evolving population of students, researchers, and practitioners who are integrating their work to provide advanced diagnosis, prevention and treatment of human disease. With advances in high-throughput technologies propelling the closer integration of lab and clinical work, this edition bridges the gap between high-level molecular genetics and clinical application.

    • Research in Protozoology

      • 1st Edition
      • October 2, 2013
      • Tze-Tuan Chen
      • English
      • eBook
        9 7 8 1 4 8 3 2 1 4 6 1 0
      Research in Protozoology, In Four Volumes covers the entire field of protozoology, including morphology, physiology, genetics, reproduction, movement, respiration, morphogenesis, nutrition and growth, immunology, ecology, effects of radiation, parasitology, taxonomy, and others. The book describes the heterogeneous complex of organelle systems and inclusion bodies which are suspended in the cytoplasmic matrix; the motile behavior of protozoa; and the respiratory metabolism of phytoflagellates, Trypanosomidae, Trichomonadidae, termite flagellates, Opalina, ciliates, and Sarcodina. The book then discusses the contractile vacuoles; ionic regulation; and excretion, as well as the nutrition and growth of protozoa. Protozoologists and zoologists and students taking these courses will find the book invaluable.

    • Brown Sugar and Health

      • 1st Edition
      • October 22, 2013
      • I. I. Brekhman + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 1 7 4 1 7 4
      • eBook
        9 7 8 1 4 8 3 1 8 9 9 8 7
      Brown Sugar and Health is a 10-chapter book on the properties and effects of using brown sugar as a substitute for white sugar. The book first highlights human health, and then discusses the relationship of health and food. Next, the text explains why using refined (or white) sugar is claimed “deadly.” It then shifts to the description of brown sugar and its actions in human body based on the experiments. Some observations on the effects of brown sugar are also examined. The text will be helpful to students and practitioners of human nutrition, food technology, and medicine.

    • The Value of Agricultural Land

      • 1st Edition
      • October 22, 2013
      • Colin Clark
      • English
      • Paperback
        9 7 8 1 4 8 3 1 2 6 5 0 0
      • Hardback
        9 7 8 0 0 8 0 1 7 0 7 0 1
      • eBook
        9 7 8 1 4 8 3 1 5 8 9 2 1
      The Value of Agricultural Land is concerned with the value of agricultural land and covers topics ranging from land rents, transport costs, and land use as well as land prices and agricultural rents. This book has seven chapters; the first of which discusses the principles underlying the value of agricultural land, with emphasis on rent and the views of David Ricardo. The next chapter focuses on Von Thünen’s theory of rents, transport costs, and land use. In particular, it examines Von Thünen’s argument that transport costs were the cause, and rents the consequence, of important differentiations of agricultural, dairy, and forest production, according to distance from the market. The use of production functions and programming to estimate the marginal productivity of land is then explained, along with agricultural rents actually paid in different countries and periods. This book concludes with an analysis of prices of land in relation to ""residual incomes."" Agricultural economists and policymakers will find this book extremely helpful.

    • The Biology of the Coleoptera

      • 1st Edition
      • September 3, 2013
      • R. A. Crowson
      • English
      • Paperback
        9 7 8 1 4 8 3 2 0 4 1 7 8
      • eBook
        9 7 8 1 4 8 3 2 1 7 6 0 4
      The Biology of the Coleoptera covers the branches of modern biology of Coleoptera. The book discusses the biological study of beetles; some skeletal peculiarities and the internal structures of the adults. The text also describes some structural features of larvae and pupae; food, digestion and the alimentary canal; and blood, osmoregulation, reserves, excretion and endocrine organs. The locomotion, respiration and energetics; the senses; and the cuticular properties, appearance, color and luminosity are also considered. The book further tackles the adult and larval behavior; the development and life-cycles; and the cytology and genetics. The text also looks into water beetles; special habitats; predation and defence; and symbiotic and parasitic relations. The ecological triangle: beetles, fungi and trees; and herbivorous beetles are also looked into. The book also discusses the role of beetles as ecological indicators; and the evolutionary history of beetles. Entomologists, ecologists, and biologists will find the book useful.

    • Textbook of Special Pathological Anatomy of Domestic Animals

      • 1st Edition
      • October 2, 2013
      • Paul Cohrs
      • English
      • eBook
        9 7 8 1 4 8 3 2 8 2 7 9 4
      Textbook of Special Pathological Anatomy of Domestic Animals should not be regarded merely as a textbook for students, but rather as one which will also be of assistance to them in their later work, as well as to veterinarians generally working in the various branches of the profession, in the assessment of pathological changes. As many new diseases have become known and much new information relating to pathogenesis and aetiology has been gained since the appearance of the last edition, radical revision of the book has become imperative. The discussions in this book cover the circulatory system, blood-forming organs, reticulo-endothelial system, respiratory system, digestive organs, peritoneum, nervous system, urinary organs, genital organs, organs of locomotion, endocrine glands, and skin.

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