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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

    • Nitrogen Heterocycles in Cancer Therapy

      • 1st Edition
      • October 14, 2025
      • Sanjeev Kumar Sahu + 1 more
      • English
      Nitrogen Heterocycles in Cancer Therapy offers an in-depth exploration of the latest nitrogen-containing heterocyclic compounds used in the fight against cancer. Across ten chapters, the book lays a solid foundation in oncology while delving into the design, synthesis, and anticancer mechanisms of these compounds. Drawing from current research, it examines how these molecules are engineered to target cancer cells, and highlights both in-vitro and in-vivo evaluation techniques. Through clear explanations and detailed analysis, the book provides readers with a comprehensive understanding of molecular strategies and promising new agents shaping modern cancer therapy.In addition to covering the science behind these compounds, the book presents clinical study reports demonstrating their effectiveness across various cancer types. It also discusses the global market impact, pharmacoeconomics, and future directions for drug development. By integrating the latest advancements and practical insights, this work stands out as an invaluable resource for researchers, clinicians, and students seeking to stay at the forefront of innovative cancer treatments.
    • Future of Internet of Bio-Nano Things in Personalized Healthcare

      • 1st Edition
      • October 14, 2025
      • Jayachitra Sekar + 3 more
      • English
      • Paperback
        9 7 8 0 4 4 3 2 7 6 0 4 0
      • eBook
        9 7 8 0 4 4 3 2 7 6 0 5 7
      Future of Internet of Bio-nano Things in Personalized Healthcare: Applications and Challenges explores the core principles of nanomaterials and the sensing paradigms essential for medical devices based on nano-sensors technology, examining the latest theoretical and practical developments in Internet of Bio-nano Things (IoBNT) for health applications. This book explores how IoBNT facilitates the detection and treatment of diseases within the human body through communication between an in-body network of nanodevices and an external control unit. Readers will discover the transformative benefits of IoBNT, which integrates information and communication technologies with medical and nano-bio sensor devices to enhance patient care. The book highlights advances in telemedicine, including highly functional electronic medical devices like implantable and wearable devices engineered through nanotechnology. It details real-time case studies on smart drug delivery, edge computing, and personalized healthcare applications to provide valuable insights into optimizing network performance and utilization in personalized healthcare. The comprehensive exploration of machine learning algorithms and communication protocols further equips readers with the knowledge to design and implement end-to-end IoBNT solutions.
    • Isothermal Titration Calorimetry in Enzymology

      • 1st Edition
      • October 13, 2025
      • Anthony Mittermaier + 1 more
      • English
      • Paperback
        9 7 8 0 4 4 3 2 1 8 4 8 4
      • eBook
        9 7 8 0 4 4 3 2 1 8 4 9 1
      Isothermal Titration Calorimetry in Enzymology: Techniques and Applications provides a thorough, practical overview of ITC as a productive and powerful tool for quantifying enzyme catalysis and interactions with substrates, products, cofactors, and inhibitors. Here, global experts in the methodology discuss the full capabilities of ITC and how it may be applied in research, medicine, and industry and offer a basis to continue leveraging ITC as its uses expand and evolve. This book bridges the gap between research and application by giving extensive technical details on cutting edge ITC techniques across a wide swath of both ITC kinetics measurements and ITC thermodynamic measurements, alongside case studies illustrating the depth of knowledge that can be obtained. Applications discussed include measuring binding kinetics by ITC, analyzing ITC kinetic data, in vivo enzyme kinetics by ITC, analyzing enzyme kinetics in crowded solutions, studying catalysis of biological substrates, interpreting ITC binding curves, ITC in drug discovery, ITC in the development of cancer therapeutics, ITC analysis of aminoglycoside resistance enzymes, studying enzyme interactions with toxic metals, using ITC to study ubiquitination, and ITC studies of glycoside hydrolases, among others.
    • Maternal-Fetal and Neonatal Endocrinology

      • 2nd Edition
      • October 13, 2025
      • Christopher S. Kovács + 1 more
      • English
      • Hardback
        9 7 8 0 4 4 3 2 3 9 4 0 3
      • eBook
        9 7 8 0 4 4 3 2 3 9 4 1 0
      Maternal-Fetal and Neonatal Endocrinology: Physiology, Pathophysiology, and Clinical Management, Second Edition continues to systematically examine the normal and abnormal endocrinology of the pregnant and lactating female and of the fetus and neonate. This new edition expands coverage of specific disorders and diseases beyond the current endocrinology content on the market making it the go-to reference for translational and clinical research scientists to appreciate the research gaps that require further investigation. It’s comprehensive coverage of pathophysiology, diagnosis, and treatments, will help readers better understand how various diseases present differently in pregnancy and lactation and how to respond to related complications.
    • Sleep and Cancer

      • 1st Edition
      • October 11, 2025
      • Maria Paola Mogavero + 3 more
      • English
      • Paperback
        9 7 8 0 4 4 3 2 8 9 3 8 5
      • eBook
        9 7 8 0 4 4 3 2 8 9 3 9 2
      Sleep and Cancer compiles novel information on the interactions between sleep and cancer. The book highlights how prevention and treatment of sleep disturbances in clinical cancer practice helps prevent the onset of tumors and their comorbidities, both short- and long-term. It analyzes how sleep disorder treatment improves the response to antitumor therapy in the long term, presenting procedures regarding cognitive-behavioral therapy of sleep disorders that are often overlooked in the oncological field.In addition, the book suggests new therapeutic approaches in oncology that are based on the knowledge of sleep mechanisms, such as chronotherapy, use of melatonin as an adjuvant in chemo- and radiotherapy, and orexinergic drugs.
    • Climate Change and Disability

      • 1st Edition
      • October 7, 2025
      • Marcalee Alexander + 2 more
      • English
      • Paperback
        9 7 8 0 4 4 3 3 1 5 6 8 8
      • eBook
        9 7 8 0 4 4 3 3 1 5 6 9 5
      Until recently, little attention has been paid to the plight of persons with disabilities during extreme weather events and/or natural disasters. Little attention has also been paid to the special needs of children with disabilities growing up in a changing world and the elderly who may rely on others for their day-to-day needs. Climate Change and Disability: A Collaborative Approach to a Sustainable Future delineates the general and specific risks of climate change for persons with disabilities and how we can use accessible approaches to mitigate, adapt and control these risks, while maximizing opportunities for persons living with disabilities. The book opens with an introduction on how we got here. The next chapters cover the framework for research and policy, the physiologic impact of different disabilities, and an overview of specific continents and countries; where hot issues related to climate change exist. Education and advocacy are covered in detail, and the book wraps up with a section on action and research, detailing how to respond to extreme weather events, including how various types of disabilities are impacted by different events. Climate Change and Disability: A Collaborative Approach to a Sustainable Future serves as a guide for a broad audience at the crossroads of environmental adaptation and human health. Rehabilitation physicians as well as physical and occupational therapists will find it valuable for tailoring care for people with disabilities due to climate change. Advocates and individuals with disabilities will gain insight into advocacy for inclusive policies and personal preparedness. Physicians and social scientists interested in the health and societal impacts of climate change will find it useful in informing their practices and research. Policymakers and politicians can utilize this resource to develop equitable climate strategies, ensuring that environmental justice includes those who are most vulnerable.
    • Advancements in the Treatment and Prevention of Breast Cancer

      • 1st Edition
      • October 7, 2025
      • Dileep Kumar
      • English
      • Paperback
        9 7 8 0 4 4 3 3 3 6 5 3 9
      • eBook
        9 7 8 0 4 4 3 3 3 6 5 4 6
      Advancements in the Treatment and Prevention of Breast Cancer highlights the significance of early detection, risk assessment, and comprehensive care in mitigating the burden of breast cancer within communities. It not only offers insights into the genetic basis of breast cancer susceptibility, familial risk assessment, and emerging genetic testing technologies but also empowers patients and their families with knowledge about available treatment options, clinical trials, and support resources.In 14 chapters this book provides an in-depth analysis of translational research focusing on understanding the etiology of breast cancer, elucidating potential avenues for primary prevention strategies. It offers a comprehensive overview of recent breakthroughs in understanding the molecular mechanisms underlying breast cancer development and discussing novel targeted treatment approaches derived from these advances but also discusses strategies for minimizing treatment-related toxicity in breast cancer management, including supportive care measures and personalized treatment approaches. This book is a valuable resource for anyone interested in the latest developments in breast cancer care and provides clear explanations of complex scientific topics and will offer insights that can help improve patient care and outcomes.
    • Data-Driven Diagnostics and Disease Prediction with AI Optimization

      • 1st Edition
      • October 6, 2025
      • Shailendra Pratap Singh + 3 more
      • English
      • Paperback
        9 7 8 0 4 4 3 2 6 7 4 7 5
      • eBook
        9 7 8 0 4 4 3 2 6 7 4 8 2
      Data-Driven Diagnostics and Disease Prediction with AI Optimization provides useful insights into model creation, data preparation, and ethical issues for healthcare applications. The book covers all the conventional and non-conventional methods related to this domain. It also discusses AI-based optimization techniques, Machine Learning models, and Advanced AI, offering practical insights, case studies, and optimization strategies to help data scientists and researchers efficiently employ AI in diagnostics and illness prediction in a world where precise diagnostics and early illness prediction may save lives and healthcare resources.
    • Artificial Metalloproteins

      • 1st Edition
      • Volume 720
      • October 6, 2025
      • English
      • Hardback
        9 7 8 0 4 4 3 4 1 5 7 3 9
      • eBook
        9 7 8 0 4 4 3 4 1 5 7 4 6
      Artificial Metalloproteins covers artificial metalloproteins (ArMs) and how they have emerged as powerful vehicles with which to control, implement, and leverage the unique reactivity and spectroscopic properties of their bound metal ions. Chapters in this release include Incorporating Non-Native Cofactors into Heme Proteins, Designing 4-Helix Bundles to Bind Porphyrin/Porphyrin-... Cofactors, Cobalt-Substituted Hemoprotein Expression, Rationally designed directed evolution of cytochrome P450 enzymes, De novo design of a switchable a-helical hemoprotein, Primary Coordination Sphere Part B: Unnatural Metal-Binding Sites Beyond the Heme, and more.Other sections cover Unnatural Amino Acid Incorporation for Creating Artificial Metalloenzymes, Development of a PQQ-Dependent Artificial Metalloprotein, Evolutionary Engineering of a Rhodium Complex-Linked Artificial Metalloenzyme, Design and Application of Nonheme Iron Enzymes, Part C: Secondary Sphere Modulation for Metallocofactor Activation, Designing Artificial Metalloenzymes by Engineering the Primary and Secondary Coordination Sphere in Native Protein Scaffolds, and much more.
    • Fungal and Protozoan Carbonic Anhydrases

      • 1st Edition
      • Volume 57
      • October 3, 2025
      • English
      • Hardback
        9 7 8 0 4 4 3 3 1 3 9 4 3
      • eBook
        9 7 8 0 4 4 3 3 1 3 9 5 0
      Fungal and Protozoan Carbonic Anhydrases, Volume 57 in The Enzymes series, explores recent advancements in the study of fungal and protozoan carbonic anhydrases (CAs). This volume presents a comprehensive collection of chapters covering various aspects of these enzymes, including an overview of fungal and protozoan CAs (genetics, molecular biology, and phylogenetics), the structure and function of fungal α-carbonic anhydrases, and an in-depth look at β-carbonic anhydrases in Saccharomyces cerevisiae, Candida spp., and Cryptococcus neoformans.Additiona... chapters delve into the Malassezia spp. and Sordaria macrospora CAs, as well as protozoan CAs from Plasmodium falciparum, Trypanosoma cruzi, Leishmania spp., Toxoplasma gondii, and Entamoeba histolytica. The volume also addresses the challenges in developing selective fungal and protozoal CA inhibitors as anti-infective agents, providing insights into their potential biomedical applications.