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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

BooksJournals

    • Growth in Animals

      • 1st Edition
      • May 3, 2017
      • T.L.J. Lawrence
      • English
      • Hardback
        9 7 8 0 4 0 8 1 0 6 3 8 2
      • Paperback
        9 7 8 1 4 8 3 1 2 9 4 3 3
      • eBook
        9 7 8 1 4 8 3 1 6 1 8 5 3
      Studies in the Agricultural and Food Sciences: Growth in Animals discusses the more advanced concepts of growth, its changes and effects on different animals and systems, and its implications for agriculture. Based on a symposium of the same name, the book defines growth and its effects on the whole body; the biochemical and genetic determinants that affect it; and the effect of thermal environment on growth and its relation with immunity. Growth of bones, muscle nucleic acid and protein, and adipose tissue are also explained. The text also encompasses the relation of growth and gut microflora; the effects of growth-promoting agents in ruminant animals and single-stomach animals; and growth and breeding performance in animals. The growth in mammals and birds for meat production and its effects on the meat quality of animals are also covered in this book. This monograph is recommended for those who would want to start or are currently running animal and poultry farms, as well as for scientists who wish to study the phenomenon of growth for the betterment of agriculture.

    • The Microbiology of Skin, Soft Tissue, Bone and Joint Infections

      • 1st Edition
      • Volume 2
      • April 25, 2017
      • Kateryna Kon + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 1 0 7 9 9
      • eBook
        9 7 8 0 1 2 8 1 1 0 9 3 5
      The Microbiology of Skin, Soft Tissue, Bone and Joint Infections: Volume 2 discusses modern approaches in diagnosis, treatment, and prophylaxis of skin, soft tissue, bone, and joint infections. The volume has been divided into three sections. The first section includes chapters on diagnosis, treatment, and prophylaxis of skin and soft tissue infections. It discusses antimicrobial and surgical treatment of wounds, diabetic foot, and different soft tissue infections. Ten chapters are devoted to cutaneous and musculoskeletal infections in special groups of patients, which have their own specificity, i.e. in pediatric and HIV-infected patients. Together with chapters on commonly present diseases, there are chapters which discuss interesting but not well studied pathologies (natal cleft pilonidal sinus) and pathogens (Malassezia and Shewanella spp.). The second section reviews etiology, pathogenesis, diagnosis and treatment of bone and joint infections, mainly osteomyelitis and prosthetic joint infections. Also, one chapter in this section discusses a newly emerging bacterial pathogen that causes skeletal infections, Kingella kingae. The third section incorporates alternative and new approaches—such as nanotechnology, ultrasound, novel delivery approaches and phyto-derived medicines—to the treatment and prophylaxis of skin, soft tissue, bone, and joint infections.

    • Genetics of Bone Biology and Skeletal Disease

      • 2nd Edition
      • October 31, 2017
      • Rajesh V. Thakker + 3 more
      • English
      • Hardback
        9 7 8 0 1 2 8 0 4 1 8 2 6
      • eBook
        9 7 8 0 1 2 8 0 4 1 9 8 7
      Genetics of Bone Biology and Skeletal Disease, Second Edition, is aimed at students of bone biology and genetics and includes general introductory chapters on bone biology and genetics. More specific disease orientated chapters comprehensively summarize the clinical, genetic, molecular, animal model, molecular pathology, diagnostic, counseling, and treatment aspects of each disorder. The book is organized into five sections that each emphasize a particular theme, general background to bone biology, general background to genetics and epigenetics, disorders of bone and joint, parathyroid and related disorders, and vitamin D and renal disorders. The first section is specifically devoted to providing an overview of bone biology and structure, joint and cartilage biology, principles of endocrine regulation of bone, and the role of neuronal regulation and energy homeostasis. The second section reviews the principles and progress of medical genetics and epigenetics related to bone disease, including genome-wide association studies (GWAS), genomic profiling, copy number variation, prospects of gene therapy, pharmacogenomics, genetic testing and counseling, as well as the generation and utilizing of mouse models. The third section details advances in the genetics and molecular biology of bone and joint diseases, both monogenic and polygenic, as well as skeletal dysplasias, and rarer bone disorders. The fourth section highlights the central role of the parathyroids in calcium and skeletal homeostasis by reviewing the molecular genetics of: hyperparathyroidism, hypoparathyrodism, endocrine neoplasias, and disorders of the PTH and calcium-sensing receptors. The fifth section details molecular and cellular advances across associated renal disorders such as vitamin D and rickets.

    • Multifunctional Systems for Combined Delivery, Biosensing and Diagnostics

      • 1st Edition
      • May 3, 2017
      • Alexandru Mihai Grumezescu
      • English
      • Paperback
        9 7 8 0 3 2 3 5 2 7 2 5 5
      • eBook
        9 7 8 0 3 2 3 5 2 7 2 6 2
      Multifunctional Systems for Combined Delivery, Biosensing, and Diagnostics explores how multifunctional nanocarriers are being used in combined delivery and diagnostics in contemporary medicine. Particular attention is given to efforts to i) reduce the side effects of therapeutic agents, ii) increase the pharmacological effect, and iii) improve aqueous solubility and chemical stability of different therapeutic agents. The chapters focus on applications of nanostructured materials and nanocarriers, highlighting how these can be used effectively in both diagnosis and delivery. This applied focus makes the book an important reference source for those wanting to learn more about how specific nanomaterials and nanotechnology systems can help to solve drug delivery and diagnostics problems. This book is a valuable resource for materials scientists, bioengineers, and medical researchers who are looking for an applications-oriente... guide on how nanotechnology and nanomaterials can be used effectively throughout the medical treatment process, from diagnosis to treatment.

    • The Natural Anti-Gal Antibody as Foe Turned Friend in Medicine

      • 1st Edition
      • September 5, 2017
      • Uri Galili
      • English
      • Paperback
        9 7 8 0 1 2 8 1 3 3 6 2 0
      • eBook
        9 7 8 0 1 2 8 1 3 3 6 3 7
      The Natural Anti-Gal Antibody as Foe Turned Friend in Medicine provides a comprehensive review of the natural anti-Gal antibody, which is the most abundant antibody in humans constituting ~1% of immunoglobulins and the carbohydrate antigen it recognizes, the α-gal epitope. It discusses the discovery of this antigen/antibody system, its evolution in mammals, the pathological effects of this antibody, and its possible use in various therapies in humans. Most significantly, the book discusses microbial and regenerative therapies in which an antibody present in all humans may be harnessed as an in vivo pharmaceutical agent that enables a wide variety of therapies. Some of these therapies are described as experimental studies that are compiled in this book, other already studied therapies in the area of cancer immunotherapy are also included in this book.

    • New Approaches to Aortic Diseases from Valve to Abdominal Bifurcation

      • 1st Edition
      • November 15, 2017
      • Ion C. Tintoiu + 4 more
      • English
      • Paperback
        9 7 8 0 1 2 8 0 9 9 7 9 7
      • eBook
        9 7 8 0 1 2 8 0 9 9 8 0 3
      New Approaches to Aortic Disease from Valve to Abdominal Bifurcation provides a complete look at aortic valve diseases from all points of view, including etiology, physiopathology, prevention, diagnosis and treatment. The book offers new insights into the aortic valve and pathology based on evidence of current diagnostic methods, treatments and post-surgery evolution. Content is split into three distinct parts for ease of reference, including an overview of aortic pathology, diagnostic evaluations methods, and treatments. Also included are guidelines and future research directions, making this a must-have volume for all cardiologists and cardiovascular surgeons who address significant issues in this topic area.

    • Omics Technologies and Bio-engineering

      • 1st Edition
      • December 1, 2017
      • Debmalya Barh + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 8 0 4 6 5 9 3
      • eBook
        9 7 8 0 1 2 8 0 4 7 4 9 1
      Omics Technologies and Bio-Engineering: Towards Improving Quality of Life, Volume 1 is a unique reference that brings together multiple perspectives on omics research, providing in-depth analysis and insights from an international team of authors. The book delivers pivotal information that will inform and improve medical and biological research by helping readers gain more direct access to analytic data, an increased understanding on data evaluation, and a comprehensive picture on how to use omics data in molecular biology, biotechnology and human health care.

    • Polycomb Group Proteins

      • 1st Edition
      • January 1, 2017
      • Vincenzo Pirrotta
      • English
      • Hardback
        9 7 8 0 1 2 8 0 9 7 3 7 3
      • eBook
        9 7 8 0 1 2 8 0 9 8 2 2 6
      Polycomb Group Proteins is a comprehensive volume detailing the mechanisms that are key to the management of genome function in many different contexts, from embryonic stem cells to terminal differentiation. The book discusses the regulation of cell lineages, cell proliferation, apoptosis, X chromosome inactivation, and most major genome programming choices. In the last few years, the biochemical understanding of PRC1-type complexes has greatly expanded in terms of the number of components involved and the intricacies of their interactions. The functionalities of these various complexes and their components are not all well understood, but recent work has shown an important division of labor and roles in the recruitment of stable binding in the ability to lay the groundwork of histone modifications and in the epigenetic maintenance of repressed states. In an effort to provide clarity in this topical research area, the book provides a cluster of chapters that deal with variant PRC1 complexes, their taxonomy, their components, their interactions, and what is known of their functions.

    • Handbook of Epigenetics

      • 2nd Edition
      • July 10, 2017
      • Trygve O. Tollefsbol
      • English
      • Hardback
        9 7 8 0 1 2 8 0 5 3 8 8 1
      • eBook
        9 7 8 0 1 2 8 0 5 4 7 7 2
      Handbook of Epigenetics: The New Molecular and Medical Genetics, Second Edition, provides a comprehensive analysis of epigenetics, from basic biology, to clinical application. Epigenetics is considered by many to be the new genetics in that many biological phenomena are controlled, not through gene mutations, but rather through reversible and heritable epigenetic processes. These epigenetic processes range from DNA methylation to prions. The biological processes impacted by epigenetics are vast and encompass effects in lower organisms and humans that include tissue and organ regeneration, X-chromosome inactivation, stem cell differentiation, genomic imprinting, and aging. The first edition of this important work received excellent reviews; the second edition continues its comprehensive coverage adding more current research and new topics based on customer and reader reviews, including new discoveries, approved therapeutics, and clinical trials. From molecular mechanisms and epigenetic technology, to discoveries in human disease and clinical epigenetics, the nature and applications of the science is presented for those with interests ranging from the fundamental basis of epigenetics, to therapeutic interventions for epigenetic-based disorders.

    • Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH)

      • 1st Edition
      • May 22, 2017
      • Michael A. Sirover
      • English
      • Paperback
        9 7 8 0 1 2 8 0 9 8 5 2 3
      • eBook
        9 7 8 0 1 2 8 0 9 8 9 8 1
      Glyceraldehyde-3-Pho... Dehydrogenase (GAPDH): The Quintessential Moonlighting Protein in Normal Cell Function and in Human Disease examines the biochemical protein interactions of the multi-dimensional protein GAPDH, further considering the regulatory mechanisms through which cells control their functional diversity. This protein’s diverse activities range from nuclear tRNA export and the maintenance of genomic integrity, to cytoplasmic post-transcriptional control of gene expression and receptor mediated cell signaling, to membrane facilitation of iron metabolism, trafficking and fusion. This book will be of great interest to basic scientists, clinicians and students, including molecular and cell biologists, immunologists, pathologists and clinical researchers who are interested in the biochemistry of GAPDH in health and disease.

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