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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

    • Epigenetics in Human Disease

      • 2nd Edition
      • May 18, 2018
      • Trygve O. Tollefsbol
      • English
      • Hardback
        9 7 8 0 1 2 8 1 2 2 1 5 0
      • eBook
        9 7 8 0 1 2 8 1 2 3 2 9 4
      Epigenetics in Human Disease, Second Edition examines the diseases and conditions on which we have advanced knowledge of epigenetic mechanisms, such as cancer, autoimmune disorders, aging, metabolic disorders, neurobiological disorders and cardiovascular disease. In addition to detailing the role of epigenetics in the etiology, progression, diagnosis and prognosis of these diseases, novel epigenetic approaches to treatment are also explored. Fully revised and up-to-date, this new edition discusses topics of current interest in epigenetic research, including stem cell epigenetic therapy, bioinformatic analysis of NGS data, and epigenetic mechanisms of imprinting disorders. Further sections explore online epigenetic tools and datasets, early-life programming of epigenetics in age-related diseases, the epigenetics of addiction and suicide, and epigenetic approaches to regulating and preventing diabetes, cardiac disease, allergic disorders, Alzheimer’s disease, respiratory diseases, and many other human maladies.
    • Digestive Diseases in Sub-Saharan Africa

      • 1st Edition
      • October 31, 2018
      • Isidor Segal
      • English
      • Paperback
        9 7 8 0 1 2 8 1 5 6 7 7 3
      • eBook
        9 7 8 0 1 2 8 1 5 6 7 8 0
      Digestive Diseases in Sub-Saharan Africa: Changes and Challenges provides an in-depth examination into the rise of western digestive diseases in Sub-Saharan Africa (SSA). For those interested in the causes of the major diseases of the ‘West’, the patterns in Africa have always reflected on the emergence of western diseases and elucidated the pattern of these conditions and their clinical course. Coverage includes the present epidemiology of GI diseases in SSA, the trends that are occurring, and the context of other emerging diseases. Appropriate for researchers, gastroenterologists and internists, this book brings together the latest research in a single, complete volume.
    • Coronary Microvascular Obstruction in Acute Myocardial Infarction

      • 1st Edition
      • July 7, 2018
      • Giampaolo Niccoli + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 2 5 2 8 1
      • eBook
        9 7 8 0 1 2 8 1 3 3 6 1 3
      Coronary Microvascular Obstruction in Acute Myocardial Infarction: From Mechanisms to Treatment provides a comprehensive understanding of the phenomenon of coronary microvascular obstruction (CMVO) that is the main limitation of reperfusion therapies in ST-elevation myocardial infarction. It provides in-depth coverage of the phenomenon of CMVO which heavily affects prognosis by increasing the risk of death and heart failure at follow-up. A first of its kind reference dedicated solely to this topic, it is appropriate for a wide audience, from researchers, to those who aid in the management, prevention and treatment of CMVO.
    • Integration and Visualization of Gene Selection and Gene Regulatory Networks for Cancer Genome

      • 1st Edition
      • May 9, 2018
      • Shruti Mishra + 2 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 6 3 5 6 6
      • eBook
        9 7 8 0 1 2 8 1 6 3 5 7 3
      Integration and Visualization of Gene Selection and Gene Regulatory Networks for Cancer Genome helps readers identify and select the specific genes causing oncogenes. The book also addresses the validation of the selected genes using various classification techniques and performance metrics, making it a valuable source for cancer researchers, bioinformaticians, and researchers from diverse fields interested in applying systems biology approaches to their studies.
    • ODE/PDE α-synuclein Models for Parkinson’s Disease

      • 1st Edition
      • February 13, 2018
      • William E. Schiesser
      • English
      • Paperback
        9 7 8 0 1 2 8 1 4 6 1 4 9
      • eBook
        9 7 8 0 1 2 8 1 4 8 0 2 0
      ODE/PDE Alpha-Synuclein Models for Parkinson’s Disease discusses a mechanism for the evolution of Parkinson’s Disease (PD) based on the dynamics of the protein α-synuclein, a monomer that has been implicated in this disease. Specifically, α-synuclein morphs and aggregates into a polymer that can interfere with functioning neurons and lead to neurodegenerative pathology. This book first demonstrates computer-based implementation of a prototype ODE/PDE model for the dynamics of the α-synuclein monomer and polymer, and then details the methodology for the numerical integration of ODE/PDE systems which can be applied to computer-based analyses of alternative models based on the reader's interest. This book facilitates immediate computer use for research without the necessity to first learn the basic concepts of numerical analysis for ODE/PDEs and programming algorithms
    • Safety Risk Management for Medical Devices

      • 1st Edition
      • June 29, 2018
      • Bijan Elahi
      • English
      • Paperback
        9 7 8 0 1 2 8 1 3 0 9 8 8
      • eBook
        9 7 8 0 1 2 8 1 3 0 9 9 5
      Safety Risk Management for Medical Devices demystifies risk management, providing clarity of thought and confidence to the practitioners of risk management as they do their work. Written with practicing engineers, safety management professionals, and students in mind, this book will help readers tackle the difficult questions, such as how to define risk acceptance criteria and how to determine when to stop risk reduction. This book delivers not only theory, but also practical guidance for applying the theory in daily risk management work. The reader is familiarized with the vocabulary of risk management and guided through a process to ensure compliance with the international standard ISO 14971—a requirement for all medical devices. This book outlines sensible, easily comprehensible, and state-of the-art methodologies that are rooted in current industry best practices. Opening chapters introduce the concept of risk, the legal basis for risk management, and the requirements for a compliant risk-management process. The next group of chapters discusses the connection between risk management and quality systems, usability engineering and biocompatibility. This book delves into the techniques of risk management, such as fault tree analysis and failure modes and effects analysis, and continues with risk estimation, risk control, and risk evaluation. Special topics such as software risk management, clinical investigations, and security are also discussed. The latter chapters address benefit-risk analysis, and production and postproduction monitoring. This book concludes with advice and wisdom for sensible, efficient, and successful safety risk management of medical devices.
    • Normal and Pathological Bronchial Semiology

      • 1st Edition
      • November 15, 2018
      • Pierre Philippe Baldeyrou + 2 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 5 7 9 5 4
      • eBook
        9 7 8 0 1 2 8 1 5 7 9 6 1
      Normal and Pathological Bronchial Semiology: A Visual Approach provides normal endobronchial aspects, including variations, anomalies and abnormal findings. Comprehensive coverage includes preoperative airway assessment in lung surgeries, airways after surgery, including complications, process and management, and airway complications in lung transplantation patients. It is a full reference that is perfect for pulmonary researchers, chest physicians, bronchoscopists, pulmonologists and cardiothoracic surgeons.
    • Organoids and Mini-Organs

      • 1st Edition
      • March 9, 2018
      • Jamie A. Davies + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 2 6 3 6 3
      • eBook
        9 7 8 0 1 2 8 1 2 6 3 7 0
      Organs and Mini-Organs combines contributions from leading practitioners who work under the editorial control of an acclaimed researcher who also served for eight years as Editor-in-Chief of the journal Organogenesis, the first journal on this topic. The book begins with an introduction, but then delves into chapters that present advice on how to make organoids for many systems. In addition, case studies that illustrate the uses of organioids are presented, along with discussions on future directions and specific problems that need to be solved.
    • Handbook of Electronic Assistive Technology

      • 1st Edition
      • November 15, 2018
      • Ladan Najafi + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 2 4 8 7 1
      • eBook
        9 7 8 0 1 2 8 1 2 4 8 8 8
      Electronic Assistive Technology (EAT) is a subset of a wider range of products and services known as Assistive Technology (AT). AT is designed to support and enable people with disabilities, either acquired or congenital, to participate in activities with greater independence and safety. With a global aging population, it has an important role to play in enabling and supporting those with disability and their carers. Handbook of Electronic Assistive Technology discusses a range of commonly available or emerging electronic assistive technologies. It provides historical background, advice when assessing for these devices and references different models of provision. It includes both medical and engineering aspects of provision. It is anticipated that the book will support students, trainees, and newly qualified Assistive Technology Practitioners to develop their understanding of the field, by considering the variables that could potentially influence the decision-making process when assessing for and providing this equipment. It also provides a reference point for those already practicing in this field and offers coverage of a broader range of technologies than clinicians may be exposed to, in their daily work This is the first reference book to focus on a comprehensive set of electronic assistive technologies and discuss their clinical application.
    • EEG-Based Diagnosis of Alzheimer Disease

      • 1st Edition
      • April 13, 2018
      • Nilesh Kulkarni + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 5 3 9 2 5
      • eBook
        9 7 8 0 1 2 8 1 5 3 9 3 2
      EEG-Based Diagnosis of Alzheimer Disease: A Review and Novel Approaches for Feature Extraction and Classification Techniques provides a practical and easy-to-use guide for researchers in EEG signal processing techniques, Alzheimer’s disease, and dementia diagnostics. The book examines different features of EEG signals used to properly diagnose Alzheimer’s Disease early, presenting new and innovative results in the extraction and classification of Alzheimer’s Disease using EEG signals. This book brings together the use of different EEG features, such as linear and nonlinear features, which play a significant role in diagnosing Alzheimer’s Disease.