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Elsevier

Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

  • Nitrogen Heterocycles in Cancer Therapy

    • 1st Edition
    • Sanjeev Kumar Sahu + 1 more
    • English
    Nitrogen Heterocycles in Cancer Therapy explores the vast array of recently discovered nitrogen-containing heterocyclic compounds utilized in combating cancer. This comprehensive work not only highlights the fundamentals of oncology but also explains the intricacies of designing, synthesizing, and understanding the anticancer mechanisms of these compounds. Spanning across 10 chapters, the book explores the principles underlying the design, synthesis, and anticancer mechanisms of nitrogen-containing heterocyclic compounds, drawing from the latest research findings. Its scope extends beyond molecular targeting to encompass the exploration of newly identified heterocyclic compounds with potential anticancer properties. A significant emphasis is placed on crucial evaluation techniques such as in-vitro cell culture and in-vivo animal models, providing insights into the performance of these compounds in combating cancer. Particularly noteworthy is the inclusion of clinical study reports detailing the efficacy of various drug candidates across different cancer conditions, coupled with an analysis of their global market impact and pharmacoeconomics. Offering profound insights, this book emerges as an indispensable resource for researchers, clinicians, and students alike.

  • Isothermal Titration Calorimetry in Enzymology

    Techniques and Applications
    • 1st Edition
    • Anthony Mittermaier + 1 more
    • English
    Isothermal Titration Calorimetry in Enzymology: Techniques and Applications provides a thorough, practical overview of ITC as a productive and powerful tool for quantifying enzyme catalysis and interactions with substrates, products, cofactors, and inhibitors. Here, global experts in the methodology discuss the full capabilities of ITC and how it may be applied in research, medicine, and industry and offer a basis to continue leveraging ITC as its uses expand and evolve. This book bridges the gap between research and application by giving extensive technical details on cutting edge ITC techniques across a wide swath of both ITC kinetics measurements and ITC thermodynamic measurements, alongside case studies illustrating the depth of knowledge that can be obtained. Applications discussed include measuring binding kinetics by ITC, analyzing ITC kinetic data, in vivo enzyme kinetics by ITC, analyzing enzyme kinetics in crowded solutions, studying catalysis of biological substrates, interpreting ITC binding curves, ITC in drug discovery, ITC in the development of cancer therapeutics, ITC analysis of aminoglycoside resistance enzymes, studying enzyme interactions with toxic metals, using ITC to study ubiquitination, and ITC studies of glycoside hydrolases, among others.

  • Maternal-Fetal and Neonatal Endocrinology

    Physiology, Pathophysiology, and Clinical Management
    • 2nd Edition
    • Christopher S. Kovács + 1 more
    • English
    Maternal-Fetal and Neonatal Endocrinology: Physiology, Pathophysiology, and Clinical Management, Second Edition continues to systematically examine the normal and abnormal endocrinology of the pregnant and lactating female and of the fetus and neonate. This new edition expands coverage of specific disorders and diseases beyond the current endocrinology content on the market making it the go-to reference for translational and clinical research scientists to appreciate the research gaps that require further investigation. It’s comprehensive coverage of pathophysiology, diagnosis, and treatments, will help readers better understand how various diseases present differently in pregnancy and lactation and how to respond to related complications.

  • Sleep and Cancer

    • 1st Edition
    • Maria Paola Mogavero + 3 more
    • English
    Sleep and Cancer compiles novel information on the interactions between sleep and cancer. The book highlights how prevention and treatment of sleep disturbances in clinical cancer practice helps prevent the onset of tumors and their comorbidities, both short- and long-term. It analyzes how sleep disorder treatment improves the response to antitumor therapy in the long term, presenting procedures regarding cognitive-behavioral therapy of sleep disorders that are often overlooked in the oncological field.In addition, the book suggests new therapeutic approaches in oncology that are based on the knowledge of sleep mechanisms, such as chronotherapy, use of melatonin as an adjuvant in chemo- and radiotherapy, and orexinergic drugs.

  • Advancements in the Treatment and Prevention of Breast Cancer

    • 1st Edition
    • Dileep Kumar
    • English
    Advancements in the Treatment and Prevention of Breast Cancer highlights the significance of early detection, risk assessment, and comprehensive care in mitigating the burden of breast cancer within communities. It not only offers insights into the genetic basis of breast cancer susceptibility, familial risk assessment, and emerging genetic testing technologies but also empowers patients and their families with knowledge about available treatment options, clinical trials, and support resources.In 14 chapters this book provides an in-depth analysis of translational research focusing on understanding the etiology of breast cancer, elucidating potential avenues for primary prevention strategies. It offers a comprehensive overview of recent breakthroughs in understanding the molecular mechanisms underlying breast cancer development and discussing novel targeted treatment approaches derived from these advances but also discusses strategies for minimizing treatment-related toxicity in breast cancer management, including supportive care measures and personalized treatment approaches. This book is a valuable resource for anyone interested in the latest developments in breast cancer care and provides clear explanations of complex scientific topics and will offer insights that can help improve patient care and outcomes.

  • Climate Change and Disability

    A Collaborative Approach to a Sustainable Future
    • 1st Edition
    • Marcalee Alexander + 2 more
    • English
    Until recently, little attention has been paid to the concerns of people living with disabilities during extreme weather events and long-term climate changes. Climate Change and Disability: A Collaborative Approach to a Sustainable, Inclusive Future for All delineates the general and specific risks of climate change for people living with disabilities and how we can use accessible approaches to mitigate, adapt, and control these risks, while maximizing opportunities for people living with disabilities. The book opens with an introduction on how we got here. The book continues with sections on actions and research, the physiologic impact of different disabilities, and discussions of specific continents and countries, where issues related to climate change exist. Education and advocacy are covered in detail, and the book wraps up with a section on action and research, detailing how to respond to extreme weather events including how various types of disabilities are impacted by different events.Climate Change and Disability: A Collaborative Approach to a Sustainable, Inclusive Future for All serves as a guide for a broad audience at the crossroads of environmental adaptation and human health. Physicians, as well as nurses, physical and occupational therapists, and other allied health professionals will find it valuable for tailoring care for people living with disabilities due to climate change. Advocates and individuals living with disabilities will gain insight into advocacy for inclusive policies and personal preparedness. Scientists and clinicians interested in the health and societal impacts of climate change will find it useful in informing their research and practice. Policymakers and politicians can utilize this resource to develop equitable climate strategies, ensuring that environmental justice concerns are inclusive.

  • Artificial Metalloproteins

    • 1st Edition
    • Volume 720
    • English
    Artificial Metalloproteins covers artificial metalloproteins (ArMs) and how they have emerged as powerful vehicles with which to control, implement, and leverage the unique reactivity and spectroscopic properties of their bound metal ions. Chapters in this release include Incorporating Non-Native Cofactors into Heme Proteins, Designing 4-Helix Bundles to Bind Porphyrin/Porphyrin-... Cofactors, Cobalt-Substituted Hemoprotein Expression, Rationally designed directed evolution of cytochrome P450 enzymes, De novo design of a switchable a-helical hemoprotein, Primary Coordination Sphere Part B: Unnatural Metal-Binding Sites Beyond the Heme, and more.Other sections cover Unnatural Amino Acid Incorporation for Creating Artificial Metalloenzymes, Development of a PQQ-Dependent Artificial Metalloprotein, Evolutionary Engineering of a Rhodium Complex-Linked Artificial Metalloenzyme, Design and Application of Nonheme Iron Enzymes, Part C: Secondary Sphere Modulation for Metallocofactor Activation, Designing Artificial Metalloenzymes by Engineering the Primary and Secondary Coordination Sphere in Native Protein Scaffolds, and much more.

  • Data-Driven Diagnostics and Disease Prediction with AI Optimization

    • 1st Edition
    • Shailendra Pratap Singh + 3 more
    • English
    Data-Driven Diagnostics and Disease Prediction with AI Optimization provides useful insights into model creation, data preparation, and ethical issues for healthcare applications. The book covers all the conventional and non-conventional methods related to this domain. It also discusses AI-based optimization techniques, Machine Learning models, and Advanced AI, offering practical insights, case studies, and optimization strategies to help data scientists and researchers efficiently employ AI in diagnostics and illness prediction in a world where precise diagnostics and early illness prediction may save lives and healthcare resources.

  • Fungal and Protozoan Carbonic Anhydrases

    • 1st Edition
    • Volume 57
    • English
    Fungal and Protozoan Carbonic Anhydrases, Volume 57 in The Enzymes series, explores recent advancements in the study of fungal and protozoan carbonic anhydrases (CAs). This volume presents a comprehensive collection of chapters covering various aspects of these enzymes, including an overview of fungal and protozoan CAs (genetics, molecular biology, and phylogenetics), the structure and function of fungal α-carbonic anhydrases, and an in-depth look at β-carbonic anhydrases in Saccharomyces cerevisiae, Candida spp., and Cryptococcus neoformans.Additiona... chapters delve into the Malassezia spp. and Sordaria macrospora CAs, as well as protozoan CAs from Plasmodium falciparum, Trypanosoma cruzi, Leishmania spp., Toxoplasma gondii, and Entamoeba histolytica. The volume also addresses the challenges in developing selective fungal and protozoal CA inhibitors as anti-infective agents, providing insights into their potential biomedical applications.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 129
    • English
    Advances in Clinical Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Advanced Cancer Research Protocols

    • 1st Edition
    • Volume 198
    • English
    Advanced Cancer Research Protocols, Volume 198 is a comprehensive and cutting-edge resource dedicated to the latest methodologies and protocols in the field of cancer research. Topics in this new release include Introduction to Cancer Biology and Current Research Trends, Cell Culture Techniques for Cancer Research, Practical Approaches to Advanced Molecular Biology Techniques, High-throughput sequencing Technologies for Cancer Genomics, Epigenetic Analysis in Cancer Research, Proteomics and Metabolomics in Cancer Biomarker Discovery, In vivo Cancer Modeling Using Mouse Models, and much more.Other sections highlight advances in Advanced Imaging Techniques for Cancer Research, Cancer Stem Cell Analysis and Targeting, Immunotherapy and Cancer Vaccine Development, Gene Editing Techniques in Cancer Research, Single-Cell Analysis in Cancer Research, Liquid Biopsy and Circulating Tumor Cell Analysis, and Exploring the Tumor Microenvironment in Solid Cancer: From Biology to Therapy.

  • Enzymatic Production of Oligosaccharides

    From Basic Research to Industrial Production
    • 1st Edition
    • Carlos Vera + 2 more
    • English
    Enzymatic Production of Oligosaccharides: From Basic Research to Industrial Production, a volume in the Foundations and Frontiers of Enzymology series, covers the enzymes used for the extraction, synthesis, or modification of oligosaccharides, the biochemical properties of those enzymes, and potential technological applications. The book is divided into three parts, the first of which shares the fundamentals on the enzymatic synthesis of oligosaccharides. The book then explores the enzymatic production of oligosaccharides, considering a range of different oligosaccharides and production processes. Final sections cover the technological properties of oligosaccharides and potential applications across the chemical, biochemical, biotechnology, and food industries.This is a useful reference for researchers working with oligosaccharides across biochemistry, enzymology, biotechnology, food chemistry and related fields.

  • Cancer Theranostics, Second Edition

    • 2nd Edition
    • Xiaoyuan Chen + 2 more
    • English
    Cancer Theranostics, Second Edition provide updates on new molecular imaging probes and techniques for early detection of cancer and describes molecular imaging-guided cancer therapy. Discussions also include nanoplatforms, incorporating both cancer imaging and therapeutic components, as well as clinical translation and future perspectives. New to this edition is the inclusion of recent developments and a streamlined structure that leads the reader through the content more intuitively, from problem to solution. More illustrations of different forms of cancer theranostics​ are included, and this edition also contains completely new content on DNA and RNA theranostics. In addition, new case studies are featured.This new edition is published in time to meet the needs of medical researchers in a comprehensive manner, encompassing diagnostics, in vivo imaging and its use for image-guided therapy, and a variety of other miscellaneous subjects. This book is a must-have for all research scientists, medical physicists, and physician scientists in cancer experimental therapeutics and molecular imaging.

  • Kratom

    History, Science and Therapeutic Potential
    • 1st Edition
    • Jack E. Henningfield + 2 more
    • English
    Kratom: History, Science and Therapeutic Potential is the first book to address the unregulated, widespread availability of kratom, with its weak opioid and stimulant effects, coupled with limited awareness of it by healthcare professionals. Kratom has great therapeutic utility and medicinal potential, but more study, caution, and possible regulation is needed. It discusses geographical sourcing, historical uses, current worldwide uses, and potential for treatment of other medical conditions. Most exciting for healthcare professionals will be the implications of this substance's potential for treatment of diseases like depression, ADHD, PTSD, and substance-use disorder, particularly opioid use disorder (OUD).Moreover, kratom and its active alkaloid mitragynine are getting remarkable attention at federal and local governments as more than eight million Americans consume this product annually. Yet, the paucity of information for researchers and clinicians is troublesome.

  • Ovarian Cancer

    Disease, Diagnosis, and Treatment
    • 1st Edition
    • Bhupendra G. Prajapati + 2 more
    • English
    By providing a comprehensive overview of current research findings, emerging therapies, and clinical practices, Ovarian Cancer: Disease, Diagnosis and Treatment is an invaluable resource. It will not only enhance the understanding of ovarian cancer's complex biology among professionals but also guide them in applying this knowledge to improve patient outcomes The book delivers the key knowledge and information needs faced by the audience center around understanding the latest advances in the underlying pathogenesis and treatment of ovarian cancer. This encompasses a broad spectrum of requirements, from grasping the molecular and genetic factors driving ovarian cancer development to staying updated on the latest therapeutic strategies, including targeted therapies and immunotherapies. In 19 chapters Ovarian Cancer: Disease, Diagnosis and Treatment gives a timely and comprehensive coverage of advances in ovarian cancer therapy, particularly highlighting the development and utilization of Nanotheranostics technologies. This focus not only addresses a crucial and cutting-edge area of cancer treatment but also positions the book as a forward- thinking resource that delves into the potential of Nanotheranostics to revolutionize cancer diagnostics and therapy.Ovarian Cancer: Disease, Diagnosis and Treatment targets a specialized audience within the medical and scientific community, focusing on obstetricians and gynecologists, oncologists, cancer researchers, and importantly, patients with ovarian cancer. This audience selection underscores the project's dual aim of advancing scientific knowledge and directly benefiting patient care in the realm of ovarian cancer, bridging the gap between research, clinical application, and patient advocacy.

  • ​​Environmental Greenness and Cardiovascular Health​

    • 1st Edition
    • William W. Aitken
    • English
    Environmental Greenness and Cardiovascular Health provides a comprehensive understanding of how environmental factors, particularly green spaces, impact cardiovascular health. The book bridges environmental science and medical research, offering insights into how greenness contributes to the prevention and management of cardiovascular diseases.Environment... Greenness and Cardiovascular Health begins with an introduction to cardiovascular disease and environmental factors, followed by discussions on defining and measuring greenness, historical perspectives, and the physiological and psychological benefits of green spaces. It also covers urban planning, disparities in access to green spaces, longitudinal studies, future research directions, and policy implications. Environmental Greenness and Cardiovascular Health benefits researchers, medical practitioners, urban planners, and policymakers by providing the latest methodologies, practical examples, and policy recommendations. It serves as an essential resource for understanding the intersection of environment and health, promoting informed strategies for improving cardiovascular health through environmental interventions.

  • Artificial Intelligence in e-Health Framework, Volume 2

    Telemedicine Applications, Drug Delivery, Augmented Reality, and Robotics
    • 1st Edition
    • Sudip Paul + 1 more
    • English
    Artificial Intelligence in e-health Framework, Volume Two: Telemedicine Applications, Drug Delivery, Augmented Reality, and Robotics offers a comprehensive exploration of AI’s role in enhancing medical solutions. Through a focus on machine learning, deep learning, and their practical applications, this book aims to bridge the gap between theoretical advancements and real-world healthcare implementations. In addition to telemedicine advancements, the book explores AI-driven drug discovery, virtual and augmented reality innovations, robotics in medicine, and radiotherapy applications. It serves as an indispensable resource for professionals, researchers, and students eager to deepen their understanding of AI's contributions to modern healthcare.

  • New Opioid Receptor Modulators and Agonists

    Relevance for Pain and Opioid Use Disorder Management
    • 1st Edition
    • Alan David Kaye + 1 more
    • English
    New Opioid Receptor Modulators and Agonists: Relevance for Pain and Opioid Use Disorder Management provides crucial insights for developing ideal synthetic opioids. It discusses opioid receptor modulators’ structures and mechanisms, and their potential applications in treating pain, misuse, and addiction. This comprehensive resource delves into current research and therapeutic development avenues regarding opioid receptors' structure and function. Sections cover the rationale for developing allosteric modulators, identifying allosteric sites on opioid receptors, and the modulators' modes of action. Readers will gain a thorough understanding of creating ideal synthetic opioids and potential future research.It also explores pharmacogenomics, precision medicine, and various syndromes and comorbidities linked to opioid use. Lastly, it reviews novel synthetic opioids and the risks of misuse and overdose.

  • Protein Termini Part B

    • 1st Edition
    • Volume 719
    • English
    Protein termini represent a major route to protein regulation. From the moment the very first amino acid of a polypeptide chain exits the ribosome there is potential for steering from the cellular environment. This volume of <i>Methods in Enzymology Modifications and Targeting of Protein Termini</i> focuses on Protein N-termini and C-termini and their modifications which include acetylation, arginylation, myristoylation and oxidation. Also, the impact of terminal modifications is covered, in particular the impact on protein turnover and the ubiquitin E3 ligases which specifically recognize protein N-termini (N-degrons) and C-termini (C-degrons). In addition to the detailed methods and laboratory protocols, the chapters include informative overviews and reviews of the different subfields.

  • Innovation in Cell Death Research

    • 1st Edition
    • Volume 217
    • English
    Innovation in Cell Death Research, Volume 217 covers topics relating to the identification of unique signaling pathways, the discovery of biomarkers and innovative treatment strategies, neurodegenerative diseases, and immune-related disorders. Chapters in this new release include Cell Death Triad: Integrating Apoptotic, Autophagic, and Necrotic Cell Death Mechanisms, Advances in Cell Death Detection and Imaging, Informatic and data science for the cell death researches, Visualizing and Mapping Cell Death: Biochemical Tools, Techniques and Assays, and the Role of Autophagy in Cell Death and Survival: Mechanisms and Therapeutic Implications.Other sections cover the Role and Relation of Cell Death in Cancer Disease, Exploring Pyroptosis: From molecular mechanisms to cancer therapeutics, Current findings and potential applications of cell death research in ovarian cancer, PHAGEPTOSIS: A BACTERIAL CELL DEATH PROGRAM INDUCED BY CRISPR-CAS SYSTEMS, Cell death mechanisms in Drosophila: Responses to infectious challenges, and much more.

  • Encyclopedia of Evolutionary Biology

    • 2nd Edition
    • Claudia Augusta De Moraes Russo + 1 more
    • English
    Encyclopedia of Evolutionary Biology, Second Edition, Four Volume Set is a comprehensive resource containing approximately 215 chapters that covers all fundamental topics in evolutionary biology. Featuring a consistent chapter structure, this encyclopedia ensures easy navigation across the volumes. Each chapter effectively links concepts to specific systems and examples, making it an invaluable tool for anyone interested in applying evolutionary thinking to their field of study. This edition includes new or expanded topics such as human evolution, including cultural evolution and language, paleontology, the origins of life, mass extinction events, epigenetics, and metagenomics.The encyclopedia also delves into the evolution of behavior, game theory, kin selection, optimality, human microbiomes, and the diversification of viruses. With its broad coverage, this essential resource will engage readers across various educational levels, emphasizing the central role of evolutionary biology in the life sciences. It caters to a wide range of readers, from students to experienced professionals, by offering both introductory chapters and in-depth analyses.

  • Advances in Applied Microbiology

    • 1st Edition
    • Volume 132
    • English
    Advances in Applied Microbiology, Volume 132 presents a comprehensive exploration of the latest innovations in applied microbiology. The book delves into the diverse applications of microbiology across various industries, including agriculture, food production, biotechnology, environmental science, and healthcare. Through a collection of insightful chapters authored by experts in the field, readers are offered in-depth analyses of cutting-edge research, emerging trends, and practical applications of microbiological principles. From novel microbial technologies to the impact of microbiomes on human health and beyond, this book serves as a valuable resource for researchers, professionals, and students seeking to stay informed and inspired by the exciting advancements.

  • Feedback Control and Adaptive Learning in Optical-Tweezer Robotics

    • 1st Edition
    • Xiang Li + 2 more
    • English
    Feedback Control and Adaptive Learning in Optical-Tweezer Robotics is a comprehensive guide to merging robotic feedback control with optical trapping techniques in cell manipulation. It begins by providing foundational knowledge in dynamic modeling and control theory, essential for understanding optical-tweezer robotics' complexities. The book explores optical trapping principles, discussing traditional approaches' constraints and challenges. It then introduces a unified control methodology designed for dynamic adaptation to cell movement and escape scenarios, highlighting the importance of closed-loop control strategies in navigating the interaction between optical forces and robotic manipulation.Additio... the book delves into adaptive learning algorithms for real-time adjustments in unknown trapping stiffness, addressing challenges like limited field of view, stochastic disturbances, and handling multiple cells. It integrates open-access simulations and real-world experiments to reinforce theoretical concepts, offering practical examples. This unified approach's potential impact on biomedicine, biotechnology, and microscale robotics is emphasized, making it an invaluable resource for readers in these fields.

  • Development of Sensory Organs

    • 1st Edition
    • Volume 165
    • English
    Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Robotics and Artificial Intelligence for Reproductive Medicine

    • 1st Edition
    • Guanqiao Shan + 3 more
    • English
    Robotics and Artificial Intelligence for Reproductive Medicine provides fundamental principles underpinning robotic and AI techniques used for reproductive medicine. The book provides the state-of-the-art technical advances in clinical infertility treatment, along with the outlook on future challenges and opportunities of robotics and AI in reproductive medicine. It covers robotics, AI, computer vision, biomedical engineering, and reproductive medicine.

  • Emerging Paradigms in Delivery of Therapeutic Agents for the Treatment of Glioblastoma

    • 1st Edition
    • Rajeev Sharma + 4 more
    • English
    Emerging Paradigms in Delivery of Therapeutic Agents for the Treatment of Glioblastoma describes the intense research and clinical developments that are required to optimize the available treatment options and the potential side effects to heal brain cancer. The success of this strategy includes the use of validated biomarkers, appropriate patient selection criteria, strategies to prevent adverse events, and the implementation of immunotherapy in multimodal treatment approach. In 18 chapters, this title sets forth the rationales for promising therapies like immunotherapy, including immune checkpoint blockade, chimeric antigen receptor T (CAR T) cell therapy, oncolytic virotherapy, and vaccine therapy.In addition, the book reviews potential novel agents, the current status of preclinical and clinical trials, and the challenges and future perspectives in glioblastoma immuno-oncology. This book is a valuable resource for health professionals, scientists and researchers, health practitioners, students, and all those who wish to broaden their knowledge in the allied field.

  • Aging in Ophthalmology

    • 1st Edition
    • Jorge L Alio MD + 2 more
    • English
    Aging in Ophthalmology examines the aging process of the eye and how this affects the future of ophthalmology. With a strong focus on therapeutic options, the book shows the latest improvements in medical and surgical possibilities. It describes both the risks of the aging of the eye, the aging of different parts of the eye (like the retina, lens, and iris), therapeutic approaches to limit the aging processes of the eye, along with a glance into the future. This book is a valuable resource for ophthalmologists of all subspecialties and researchers interested in the aging process in the human eye.

  • Sports Physician Handbook

    • 4th Edition
    • Yannis P. Pitsiladis + 3 more
    • English
    Sports Physician Handbook, the fourth edition of the Team Physician Manual: International Federation of Sports Medicine (FIMS), covers all key areas of activity and intervention, from the preparticipation examination to rehabilitation, drug testing, care of the young athlete, the female athlete, and environmental issues. The book also surveys major classifications of sports injuries, offering clear advice on field side assessment, diagnosis, and treatment. It further examines best practices in broader aspects of sports medicine, such as injury prevention and the psychology of recovery. Sports Physician Handbook continues the tradition of high-caliber authorship, featuring contributions from world-leading physicians and scientists. In short, the fourth edition represents a "must-have" reference for any doctor, scientist, physical therapist, or medical professional working in sport.

  • Williams. Tratado de endocrinología

    • 15th Edition
    • Shlomo Melmed + 2 more
    • Spanish
    Revisada y exhaustivamente actualizada, Williams. Tratado de endocrinología, 15.ª edición, sigue siendo la principal fuente de información acreditada acerca de los trastornos del sistema endocrino adulto y pediátrico. Autores y editores de renombre mundial tienden puentes entre la ciencia básica y la información clínica, manteniendo al lector al día de los últimos avances en fármacos, terapias y ensayos clínicos, entre otros muchos temas. Este texto esencial constituye un recurso imprescindible para endocrinólogos, cirujanos endocrinos, ginecólogos, internistas, pediatras y otros profesionales que precisan una cobertura actual y completa de este multifacético campo.

  • Lipid Analysis in Biology, Health, and Disease

    • 1st Edition
    • Sanjoy K. Bhattacharya
    • English
    Lipid Analysis in Biology, Health, and Disease bridges the gap between discovery science and clinical lipidology, empowering both scientific and medical communities to apply lipid analysis and understanding in new research, as well as diagnosis and management of diseases. Here, international experts in the field begin with the basic biology of the lipids, followed by methods and technology for study, and lipids in lab medicine and epidemiology. This book uniquely combines biology and analysis to drive healthcare advances, with a diverse range of technologies and analytic methods considered.Basic lipid biology chapters discuss membrane expansion, lysosomal positioning, mitochondrial biogenesis, lipid-protein interactions, molecular dynamics, cholesterol transport, immune activation and inflammation, lipid droplets, and gender differences in lipid metabolism. Each disease chapter incorporates basic lipid epidemiology, risk factors, and genetic associations.

  • Complicaciones crónicas de la diabetes mellitus. Perspectivas actuales y nuevas claves fisiopatológicas

    • 1st Edition
    • Didac Mauricio + 1 more
    • Spanish
    Entre las complicaciones de la diabetes se incluyen alteraciones patológicas que suelen relacionarse con el sistema vascular y los órganos diana habituales. Sin embargo, también hay complicaciones menos frecuentes, total o parcialmente independientes de la lesión vascular, que suelen pasarse por alto. Este libro ofrece una visión holística de la enfermedad y aborda no solo sus complicaciones habituales, sino también las afecciones menos conocidas y tratadas que se asocian a la diabetes. También se exponen los avances alcanzados en la comprensión de la arquitectura genómica de las complicaciones de la diabetes y cómo se puede utilizar la medicina de precisión para personalizar el tratamiento. Este libro es una obra exhaustiva sobre el tema, dirigida a endocrinólogos, diabetólogos, médicos de atención primaria e investigadores interesados en las complicaciones de la diabetes y en la información más actualizada al respecto.

  • Generative Artificial Intelligence and Ethics for Healthcare

    • 1st Edition
    • Loveleen Gaur + 1 more
    • English
    Generative Artificial Intelligence and Ethics for Healthcare conducts a deep dive into the potential issues and challenges associated with Generative AI applications. The book begins with foundational concepts of generative AI and then explores ethical theories, including specific case studies in healthcare, and concludes with discussions on policy and future implications. Written for healthcare professionals, policymakers, academics and AI developers, by authors who have a thorough understanding of AI and machine learning in the healthcare.

  • Federated Learning in Metaverse Healthcare

    Personalized Medicine and Wellness
    • 1st Edition
    • Shubham Mahajan + 1 more
    • English
    Federated Learning in Metaverse Healthcare: Personalized Medicine and Wellness explores the integration of the metaverse with healthcare, offering immersive experiences and personalized care. The book introduces federated learning, emphasizing its advantages over traditional centralized machine learning in healthcare. It provides a historical context and discusses the technological advancements that led to the emergence of metaverse healthcare. Privacy-preserving methods crucial for protecting sensitive healthcare data within federated learning environments are also examined, underscoring the importance of secure communication protocols. Other important points include the transformation of healthcare delivery through virtual environments, remote consultations, and immersive experiences.The role of telemedicine in facilitating remote diagnostics and consultations via virtual platforms, and the applications of augmented reality wearables for real-time health monitoring and wellness tracking are detailed. Additionally, the book discusses federated learning's ability to deliver personalized treatment plans tailored to individual patient needs, its role in predictive modeling for disease risks and prevention, as well as virtual health coaches offering personalized guidance for wellness management. The challenges and ethical dilemmas of metaverse healthcare and federated learning, along with potential solutions, are also considered.

  • Protein Structure Prediction and Analysis

    • 1st Edition
    • Volume 147
    • English
    Protein Structure Prediction and Analysis, Volume 146 offers a comprehensive exploration of the methodologies, tools, and techniques utilized in the prediction and analysis of protein structures. The book delves into the fundamental principles of protein folding, modeling, and computational simulations, providing insights into the intricate process of predicting the three-dimensional structures of proteins. Sections in this new release include coverage of Current approaches for protein structure prediction and design, Protein Modelling, Prediction servers and applications in molecular modelling, Toward accurate in silico prediction of antigen binding affinities in antibody engineering, Molecular Blueprints: Guiding Drug Discovery through Protein Structure Analysis, and much more.Additional sections focus on Protein Structure Prediction Using Dynamic Speciation Evolutionary Algorithm with Problem Information Aggregation, Tau protein structure and dynamics, Tau interacts with G-protein coupled receptors (GPCRs), How to accurately predict nanobody structure: Classical physics-based simulations or deep learning approaches, Medicinal Chemistry-based Novel Therapeutics for Tauopathies in Alzheimer’s Disease, Mapping the Pathogenic Nexus: Gene Overlap and Protein Interaction Networks in Alzheimer's and Breast Cancer as a Precursor to Protein Structure Prediction and Analysis, and much more.

  • Nanotheranostics and Precision Oncology

    • 1st Edition
    • Ramish Riaz + 4 more
    • English
    Nanotheranostics and Precision Oncology delves into the merging fields of cancer research and nanotechnology, offering a thorough review of the latest advancements in precision oncology. It begins with an exploration of cancer biology, illuminating the genetic foundations of oncogenesis alongside the cellular and molecular mechanisms driving cancer progression, metastasis, and drug resistance. This resistance remains the foremost challenge in cancer care. Across 28 chapters, the book addresses precision medicine's role in overcoming drug resistance, the importance of biomarkers, the interpretation of genetic analyses, and the shift toward personalized oncology.In addition, the book examines nanotheranostics' applications and mechanisms in cancer diagnosis and treatment, integrating them with precision oncology. It outlines the design, mechanism, and impact of nanoprecision medicine in cancer management. The final section considers the future of nanotheranostics in precision oncology and the challenges of translating these innovations from research to clinical practice. This comprehensive guide serves students, clinicians, researchers, and the pharmaceutical industry involved in nanomedicine, oncology, molecular biology, and precision medicine.

  • Animal Models of Disease Part D

    • 1st Edition
    • Volume 197
    • English
    Animal Models of Disease, Part D, Volume 197 in the Methods in Cell Biology series presents significant advancements in understanding disease mechanisms through animal models. This volume features chapters on timely topics such as characterizing tumor-infiltrating group 1 innate lymphoid cells in PyMT breast tumors and using zebrafish to unravel the molecular mechanisms of Alzheimer’s disease. The book also covers colitis mouse models and appropriate models for studying diabetes pathophysiology, demonstrating its comprehensive approach to current research.Additional sections cover evaluating polyglutamine protein aggregation in transgenic Caenorhabditis elegans models of Huntington's disease and studying tumor responses to radioimmunotherapy in ovarian cancer models. It also highlights the antimicrobial regime for gut microbiota depletion in mice and the biodistribution of metallic nanoparticles for lymphoma studies. This book is an essential resource for researchers seeking to explore disease mechanisms and therapeutic approaches through animal models.

  • Biliary Tract Neoplasms

    • 1st Edition
    • Timothy M. Pawlik + 1 more
    • English
    Biliary Tract Neoplasms is a state-of-art reference of the multimodality management of bile duct cancer written by leaders in the field. As targeted therapy and clinical trials in this field are exploding, and the incidence of the disease is increasing, now is the time to address the topic in practical manner. This reference addresses surgical approaches to biliary neoplasms, targeted personalized systemic approaches to biliary neoplasms, and other treatment modalities such as radiotherapy and ablation. It is intended for scientists, researchers, clinicians, practicing surgeons, surgical oncologists, transplant surgeons as well as fellows/residents in the surgical space.The book's translational nature and impact of basic science findings that have informed targeted therapy for biliary neoplasms provide the very latest data on surgery, medical, imaging, and multi-modality care of biliary neoplasm to educate and inform care of this patient population.

  • Plant-Based Drug Discovery

    Unveiling Molecular Targets for Metabolic Conditions
    • 1st Edition
    • Mamta Bisht + 2 more
    • English
    Plant-Based Drug Discovery: Unveiling Molecular Targets for Metabolic Conditions provides an in-depth examination of the molecular mechanisms of phytochemicals and their potential in treating metabolic diseases. This comprehensive guide begins with an introduction to the prevalence and impact of metabolic disorders, emphasizing the significant role of phytochemicals in their management. The book delves into scientific concepts and research findings, offering valuable insights for researchers and healthcare professionals in the fields of molecular biology, biochemistry, pharmacology, and biotechnology. Chapters cover various crucial topics such as oxidative stress, epigenetic mechanisms, and mitophagy.In addition, they explore the targeting of molecular chaperones and the molecular targets of plant nutraceuticals for treating obesity, cardiovascular disease, and type 2 diabetes. The book also addresses technological advances, including AI and nanotechnology, highlighting opportunities and challenges in improving the use of plant molecules for metabolic disorder treatments. It serves as an essential resource for those engaged in drug discovery and related areas.

  • Handbook of Intervention Science

    From Design to Implementation
    • 1st Edition
    • Laura N.Gitlin + 1 more
    • English
    Handbook of Intervention Science: From Design to Implementation discusses multiple approaches for developing and advancing interventions at the individual, family, community, health system, and policy level. The book focuses on creating interventions suitable for diverse populations from racial, ethnical, geographical, and socioeconomical perspectives. Combining best practices with a practical approach, the book enables readers to advance their intervention research. It covers intervention design, data capture in trials, and evaluation. Decision trees help illustrate when to move forward with an implementation relative to the need for further work.

  • Less-Supervised Segmentation with CNNs

    Scenarios, Models and Optimization
    • 1st Edition
    • Jose Dolz + 2 more
    • English
    Less-Supervised Segmentation with CNNs: Scenarios, Models and Optimization reviews recent progress in deep learning for image segmentation under scenarios with limited supervision, with a focus on medical imaging. The book presents main approaches and state-of-the-art models and includes a broad array of applications in medical image segmentation, including healthcare, oncology, cardiology and neuroimaging. A key objective is to make this mathematical subject accessible to a broad engineering and computing audience by using a large number of intuitive graphical illustrations. The emphasis is on giving conceptual understanding of the methods to foster easier learning.This book is highly suitable for researchers and graduate students in computer vision, machine learning and medical imaging.

  • Biosensing the Future

    Wearable, Ingestible and Implantable Technologies for Health and Wellness Monitoring Part B
    • 1st Edition
    • Volume 216
    • English
    Biosensing the Future: Wearable, Ingestible and Implantable Technologies for Health and Wellness Monitoring, Part B, Volume 216 covers the rapidly evolving field of biosensors, highlighting their transformative role in modern healthcare, disease monitoring, and personalized medicine. Chapters in this new release include Technologies and emerging trends in wearable biosensing, Implantable biosensors: advancements and applications, Neural implants: restoring function and enhancing quality of life, Ingestible biosensors: monitoring health from within, Ingestible biosensors for monitoring digestive health and nutritional monitoring, Ingestible biosensors for drug delivery monitoring, Artificial intelligence in wearable biosensing: enhancing data analysis and decision-making, and much more.Additional sections cover Wearable Privacy, Ethical and regulatory landscape of wearable, ingestible, and implantable technologies, Characterization of skeletal muscle contraction using a flexible and wearable ultrasonic sensor, Wearable Biosensors for Climate Change and Health Research, and much more. The book systematically explores the integration of biosensing technologies into wearable, ingestible, and implantable devices, offering a multidimensional perspective on their applications, advancements, and future directions.

  • Methodology in Radiomics

    Step-by-step Guide in Radiomics Pipeline
    • 1st Edition
    • Salvatore Claudio Fanni + 3 more
    • English
    Methodology in Radiomics: Step-by-step Guide in Radiomics Pipeline is an essential resource for anyone interested in the rapidly evolving field of radiomics. This comprehensive guide delves into the history and fundamental principles of radiomics, providing readers with a clear understanding of how to implement each step in the radiomic pipeline. The book is designed to bridge the gap between radiomics research and clinical practice, making it an invaluable reference for imaging scientists, researchers, and medical professionals. The book not only covers the basics but also includes troubleshooting techniques to overcome common challenges.It discusses current research and future directions, offering insights into the potential of radiomics in clinical settings. This guide ensures that readers are well-equipped to navigate the complexities of radiomics, fostering a deeper understanding of its applications and advances in medical imaging.

  • Nanomedicine Advancements and Intersectional Perspectives for Women's Health

    • 1st Edition
    • Pankaj Sharma + 1 more
    • English
    Nanomedicine Advancements and Intersectional Perspectives for Women's Health provides detailed insights and innovative treatments that specifically address health issues that women face. It provides valuable information and practical solutions based on scientific evidence providing comprehensive information about nanomedicine advancements specifically targeted towards improving health outcomes. It offers clear explanations of complex medical concepts in nanomedicine in a reader-friendly manner to help bridge the knowledge gap on this topic. By providing clear explanations, real-life examples, and practical insights, it empowers readers with valuable information that can help healthcare professionals make informed decisions working in relevant fields as well as researchers new to the field.

  • Protein Termini Part A

    • 1st Edition
    • Volume 718
    • English
    Protein termini represent a major route to protein regulation. From the moment the very first amino acid of a polypeptide chain exits the ribosome there is potential for steering from the cellular environment. This volume of Methods in Enzymology Modifications and Targeting of Protein Termini focuses on Protein N-termini and C-termini and their modifications which include acetylation, arginylation, myristoylation and oxidation. Also, the impact of terminal modifications is covered, in particular the impact on protein turnover and the ubiquitin E3 ligases which specifically recognize protein N-termini (N-degrons) and C-termini (C-degrons). In addition to the detailed methods and laboratory protocols, the chapters include informative overviews and reviews of the different subfields.

  • Applied Mathematical Modeling for Biomedical Robotics and Wearable Devices

    • 1st Edition
    • S. Sountharrajan + 3 more
    • English
    Applied Mathematical Modelling for Biomedical Robotics and Wearable Devices delves into the innovative convergence of mathematical frameworks and biomedical engineering. The book begins by exploring how advanced mathematical modelling underpins the development and optimization of robotic systems and wearable technologies tailored for medical applications. With a strong emphasis on practical implementation, it serves as a bridge between theoretical concepts and real-world engineering challenges in the healthcare sector. Readers will gain insights into the transformative role of mathematical techniques that drive precision, functionality, and human-centric design in cutting-edge medical technologies.The book also covers interdisciplinary applications, integrating domains like biomechanics, sensor technology, and data analytics. By highlighting case studies and real-world scenarios, it showcases practical advancements in wearable devices that monitor health metrics and robotic systems that assist in surgical procedures.

  • Digital Health Maturity: Quality, Interoperability, and Innovation

    • 1st Edition
    • Siaw-Teng Liaw + 3 more
    • English
    Digital Health Maturity: Quality, Interoperability, and Innovation provides a roadmap to move from endless pilots and ad hoc system purchase to a systematic, stepwise, and integrated approach to increasing digital health capacity. Specific guidelines, tools, and use cases are discussed to show how the digital health maturity metamodel (DHM3) can be put into actual practice. The book discusses topics such as foundations of digital health and how to put them into practice; organizational considerations for implementation; and best practices, tools, and pitfalls to avoid. In addition, it discusses the future of digital transformation and the impact of a global adherence to digital health. It is a valuable resource for researchers, students, policy makers, governments and anyone who is interested in learning more about digital health and its benefits worldwide.

  • Nanodermatology

    Advances in Theory and Practice
    • 1st Edition
    • Alka Lohani + 2 more
    • English
    Nanodermatology: Advances in Theory and Practice navigates the evolving landscape of skincare, offering a deep dive into the principles, innovations, and practical implications of nanotechnology in dermatological research and practice. The book addresses both basic and clinical aspects and conveys practical insights needed to navigate the complexities of nanodermatology through applied case studies, real-world examples, and actionable recommendations. From fundamental principles to diagnostic techniques, therapeutic interventions, safety considerations, ethics, and regulation, it offers practical insights for advancing nanodermatology research and application. Additionally, the inclusion of clinical uses and regulatory considerations ensures that the book offers guidance for translating nanodermatology research into practice.From enhancing drug delivery systems to advancing cosmetic formulations, this authoritative guide illuminates the cutting-edge advancements shaping the future of skincare, making it an indispensable resource for researchers, clinicians, and students alike.

  • Advances in Microbial Physiology

    • 1st Edition
    • Volume 87
    • English
    Advances in Microbial Physiology, Volume 87, the latest release in this ongoing long-established series, continues the tradition of topical, important, cutting-edge reviews in microbiology. The book's editors have strive to view microbial physiology in the broadest sense by including any topics that help us understand how micro-organisms “work”. In this volume, Chapters deal with Diversity in the physiology and metabolism of chlorophototrophic bacteria, Multiple roles for iron in microbial physiology: bacterial oxygen sensing by heme-based sensors, and A Lysis Less Ordinary: The Bacterial Type 10 Secretion System.

  • The Human Body

    Linking Structure and Function
    • 2nd Edition
    • Bruce M. Carlson
    • English
    The Human Body: Linking Structure and Function, Second Edition offers a comprehensive and accessible exploration of the human anatomy, making it an invaluable resource for students and professionals alike. Each chapter delves into a specific organ system, elaborating on how the unique structures within the body contribute to its overall functionality.Organi... by organ system, this succinct publication presents the functional relevance of developmental studies and integrates anatomical function with structure. A new chapter presents the functional anatomy of a joint, including the skeleton, muscles, connective tissues, nerves and vessels.Written by a leader in the field for upper undergraduate, graduate and postdoc market, as well as professors and researchers studying functional anatomy, developmental biology, physiology and across the life sciences, dentistry, and nursing.

  • Therapeutics of Natural and Synthetic Compounds in Protease-Induced Cancer

    • 1st Edition
    • Sajal Chakraborti
    • English
    Therapeutics of Natural and Synthetic Compounds in Protease Induced Cancer presents a detailed discussion on the role of therapeutic and synthetic compounds in proteases and how they have been utilized to develop anticancer drugs, covering both their structure and functions. In addition, the book explores the experimental and theoretical aspects of natural and synthetic compound design based on proteases. Sections bridge the gap between fundamental and translational research, with applications in the biomedical and pharmaceutical industry, making it a thought-provoking read for basic and applied scientists engaged in biomedical research.In 23 chapters, this book gives both insights on the general aspects of the role of natural and synthetic compounds in cancer therapeutics, in cancer development, treatment, and their use in clinical trails. Given the breadth and depth of information covered in the respective contributions, the book will be immensely useful for researchers in oncology and for those working to identify targets for drug development.

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