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Elsevier

Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

  • Kaufman’s Atlas of Mouse Development Supplement

    With Coronal Sections
    • 2nd Edition
    • Gillian Morriss-Kay + 1 more
    • English
    Kaufman's Atlas of Mouse Development Supplement, Second Edition continues the stellar reputation of the original Atlas by providing updated, in-depth anatomical content and morphological views of organ systems. The book explores the developmental origins of the organ systems, following the original atlas as a continuation of the standard in the field for developmental biologists and researchers across biological and biomedical sciences studying mouse development. In this new edition, each chapter has been updated to include the latest research, along with while new chapters on the functional aspects of mouse and human heart development, the immune system, and the inner ear.These additions ensure an up-to-date resource for all biomedical scientists who use the mouse as a model species for understanding the normal and abnormal development of human systems.

  • Protistology

    • 1st Edition
    • Sina M. Adl
    • English
    Protistology provides a comprehensive overview on recent developments in understanding the diversity of cell biology, genomic processes, parasite-host interactions, and the evolution of eukaryotes. The book is the first modern treatise on these organisms, walking readers through protistology’s diversity and classification. This book is an ideal supplemental text for upper-level undergraduates and graduate students in microbial ecology, freshwater and marine biology, soil ecology, environmental sciences, or those looking to initiate a course in protistology.

  • Mitophagy in Health and Disease

    Mechanisms, Health Implications, and Therapeutic Opportunities
    • 1st Edition
    • John J. Lemasters
    • English
    Mitophagy in Health and Disease: Mechanisms, Health Implications, and Therapeutic Opportunities is a complete reference to this key cellular process involved in homeostasis. The book addresses the machinery and mechanisms of mitophagy, including an overview of mito-biogenesis and dynamics and specific types of mitophagy. Other sections cover mitophagy across the human lifespan, from development to aging, discussing the interplay between inflammation and several conditions. The final part covers therapeutic opportunities presented by targeting mitophagy, including inducers and inhibitors, targeting strategies, and studies specific to cardioprotection and neurodegenerative diseases prevention.This is the ideal reference for cellular and molecular biologists needing a consistent and thorough overview of the subject, as well as research physicians in areas where mitochondria play a key role.

  • Deep Learning in Genetics and Genomics

    Volume 1: Foundations and Introductory Applications
    • 1st Edition
    • Khalid Raza
    • English
    Deep Learning in Genetics and Genomics vol. 1, Foundations and Applications, the intersection of deep learning and genetics opens up new avenues for advancing our understanding of the genetic code, gene regulation, and the broader genomics landscape. The book not only covers the most up-to-date advancements in the field of deep learning in genetics and genomics, but also a wide spectrum of (sub) topics including medical and clinical genetics, predictive medicine, transcriptomic, and gene expression studies. In 21 chapters Deep Learning in Genetics and Genomics vol. 1, Foundations and Applications describes how AI and DL have become increasingly useful in genetics and genomics research where both play a crucial role by accelerating research, improving the understanding of the human genome, and enabling personalized healthcare. From the fundamentals concepts and practical applications of deep learning algorithms to a wide range of challenging problems from genetics and genomics, Deep Learning in Genetics and Genomics vol. 1, Foundations and Applications creates a better knowledge of the biological and genetics mechanisms behind disease illnesses and improves the forecasting abilities using the different methodologies described. This title offers a unique resource for wider, deeper, and in-depth coverage of recent advancement in deep learning-based approaches in genetics and genomics, helping researchers process and interpret vast amounts of genetic data, identify patterns, and make discoveries that would be challenging or impossible using traditional methods.

  • Time-Resolved Methods in Structural Biology

    • 1st Edition
    • Volume 709
    • English
    Time-Resolved Methods in Structural Biology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Advances in Biomembranes and Lipid Self-Assembly

    • 1st Edition
    • Volume 40
    • English
    Advances in Biomembranes and Lipid Self-Assembly, Volume 40 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

  • Lanthanides in Enzymology and Microbiology

    • 1st Edition
    • Akio Tani + 2 more
    • English
    Lanthanides in Enzymology and Microbiology, a new volume in the Foundations and Frontiers in Enzymology Series, offers a detailed discussion of lanthanides and lanthanide-dependent enzyme biology. In this book, more than a dozen global experts consider lanthanide enzymology fundamentals, organismal utilization of lanthanides, distribution and diversity of lanthanide-dependent enzymes, regulation of intracellular levels of lanthanides, gene expression regulation via lanthanides, as well as likely applications of lanthanide binding proteins. Lanthanide-dependent methanol and alcohol dehydrogenase metabolism are considered in both methylotrophs and non-methylotrophs, alongside various application areas, from recovery of rare earth elements to developing lanthanide ion binding peptides and biosynthesis of terpolymers through reverse-oxidation pathways. In providing this deep context and pathways for future research, this book acts as an invaluable resource in this emerging field for researchers and students of biochemistry, biotechnology, and environmental microbiology alike.

  • Artificial Intelligence in Urologic Malignancies

    • 1st Edition
    • Himanshu Arora
    • English
    Artificial Intelligence in Urologic Malignancies describes current artificial intelligence technology, with an emphasis on prostate cancer applications. The book provides guidance on how artificial intelligence can improve therapeutics, how the power of artificial intelligence integrated with current standard therapy and research can enhance decision-making, and proposes future directions on how to integrate artificial intelligence within clinical applications. This is the perfect reference for scientists and researchers interested in the basic translational research opportunities such as drug discovery, pharmacogenetics, and experimental therapeutics, as well as clinicians interested in how AI applications are integrated with applications.

  • Truth Unveiled

    Navigating Science and Society in an Era of Doubt
    • 1st Edition
    • Faadiel Essop
    • English
    Faculty, students, researchers, and clinicians are struggling how to deal with the post-truth world as the broader public lacks an understanding of the complexity of the scientific research process. This has resulted in the dissemination of mis- and disinformation that is increasingly used to shape public opinion in medical-related matters, for example, the rise of anti-vaxxers and resistance to COVID-19 pandemic social isolation protocols. In addition, physiologists and scientists play relatively limited role when engaging the broader public in this regard. Truth Unveiled: Navigating Science and Society in an Era of Doubt provides valuable information to inform researchers and clinicians and better train students on the broader aspects of the scientific process and how to best counteract mis- and disinformation. This book is published as part of the Fundamentals of Physiology series in association with the International Union of Physiological Sciences and should be a useful resource for lecturers when training physiologists, biomedical scientists, and medical and allied health students.

  • Fundamentals of Biosensors in Healthcare

    Volume 1
    • 1st Edition
    • Md Saquib Hasnain + 2 more
    • English
    Fundamentals of Biosensors in Healthcare: Volume One provides comprehensive coverage on fundamentals while also delving into the diverse types of biosensors used in healthcare. This first of three volumes covers biosensors in healthcare and explains the history, classifications, and fundamentals of biosensing. It presents current research and the development of biosensors, while also exploring and detailing the distinct types of biosensors and their application in healthcare.Combined with Volume Two, Materials and Components of Biosensors in Healthcare and Volume Three, Applications of Biosensors in Healthcare, users will find a holistic set of reference sources that are suitable for researchers, graduate students, postgraduates, and industry professionals involved in biosensing, biosensors, and biomedical applications.

  • Implementation of Personalized Precision Medicine

    Expanding the Clinical Vision towards Prevention, Early Detection and Precision Treatment of Disease to Drive Extended Healthspan
    • 1st Edition
    • William P. Stanford + 1 more
    • English
    At the heart of precision medicine lies one concept missing from modern medicine – the unique genetic and biochemical make-up of each individual patient. Implementation of Personalized Precision Medicine: Expanding the Clinical Vision towards Prevention, Early Detection, and Precision Treatment of Disease to Drive Extended Healthspan establishes a landscape of precision medicine geared towards implementation of fully personalized approaches within precision medicine to facilitate prevention and early detection of age-related disease in each individual. This reference details how these lofty goals are now achievable with the science of today and tomorrow and provides the context, thought process and beginning blueprint to guide researchers and clinicians in more effectively considering the prevention and treatment of complex chronic disease. Uniquely organized, this reference provides insight into creating fully personalized precision medical treatments. Chapters include conventionally considered data such as genetic inherited risk, current epigenetic modifications, and current biochemical markers but also include less conventional food for thought such as microbiome, mitochondrial function, and dna repair. This provocative landscape makes this reference a valuable addition to the literature expanding precision medicine towards personalized chronic disease prevention and treatment.

  • The Pathology and Imaging of Coronavirus Pneumonia

    • 1st Edition
    • Hongjun Li + 3 more
    • English
    The Pathology and Imaging of Coronavirus Pneumonia is a comprehensive study of the coronavirus family-related pulmonary diseases, specifically targeting the three subtypes of coronaviruses that have been confirmed to infect humans: SARS, MERS, and COVID-19. It is based on heterogeneous data from imaging and clinical sources, and particularly emphasizes the imaging-based staging diagnostic model rooted in the pathogenic and pathological aspects of clinical staging, thereby aiming to better align with the requirements of evidence-based medicine in clinical diagnosis and treatment.The book provides a comprehensive overview of the pathology and imaging manifestations of coronavirus pneumonia, covering the integrated theories and practical achievements of etiology, epidemiology, pathology, clinical diagnosis, treatment, radiology, cleaning, disinfection, and protection measures commonly used in the imaging department, as well as the prevention and prognosis of SARS, MERS and COVID-19.

  • Geriatric Surgery and Perioperative Care

    • 1st Edition
    • Gabriella Bettelli + 1 more
    • English
    Geriatric Surgery and Perioperative Care presents clear evidence to support regulatory and financial decisions in the light of the value-based care principles. The book outlines standards of care for elderly patients undergoing surgery as well as minimal requirements for modern management aimed at delivering cost-effective healthcare. It opens with the epidemiology and patho-physiological changes of aging and their impact on anesthesia and surgery. Subsequent chapters guide readers through the surgical process, addressing preoperative optimization, intraoperative procedures and management, and postoperative principles, including ICU care.The book concludes with ethical principles, care models, and hospital design to support a golden silver surgery using a team-based approach. This title is an important resource for healthcare professionals, practitioners, and others pursuing current strategies and methods for successful perioperative care of the elderly.

  • The Lung

    Development, Aging and the Environment
    • 3rd Edition
    • Kent Pinkerton + 2 more
    • English
    The Lung: Development, Aging and the Environment, Third Edition provides an understanding of the multifaceted nature of lung development, aging and the environment influences of these processes. As an essential resource to respiratory, pulmonary and thoracic scientists and physicians, this book provides an interface between the "normal" and "disease" cluster of chapters, allowing for a natural complement. The interface between different lung diseases affecting the pediatric lung also adds a useful source for comparing how different lung diseases share key pathophysiological features. This same complementarity comes across in the logical line up of chapters dealing with the "normal" pediatric lung.New research, including cell-based strategies for infant lung function, epigenetics and prenatal environmental exposure (including wildfires) on lung development and function are some of the important additions to this edition of this reference work.

  • Yoga for Cardiovascular Disease and Rehabilitation

    Integrating Complementary Medicine into Cardiovascular Medicine
    • 1st Edition
    • Indranill Basu Ray
    • English
    Yoga in Cardiovascular Disease and Rehabilitation: Integrating Complementary Medicine into Cardiovascular Medicine highlights recent research, clinical trials and experiments on yoga and meditation as a preventative measure against various major cardiovascular diseases, including hypertension, hyperlipidemia, coronary artery disease and metabolic syndromes.Chapters discuss yoga's role in ameliorating cardiac dysfunction and current knowledge on the effects of yoga on the brain, emotion, and other factors that initiate and perpetuate vascular inflammation. Cellular, genetic, and molecular effects of yoga based on experimental evidence are also covered in detail, providing readers with the latest research on the effects of yoga and meditation in heart diseases.This book also explores current knowledge gaps in yoga research to facilitate further research and is a comprehensive reference to scientists and clinicians interested in yoga's health effects, including preventing and treating diseases.

  • The Three Functional States of Proteins

    Structured, Intrinsically Disordered, and Phase Separated
    • 1st Edition
    • Timir Tripathi + 1 more
    • English
    The Three Functional States of Proteins explores how structured proteins, intrinsically disordered proteins, and phase separated proteins contribute to the complexity of cellular life, and offers insights into their roles in both health and disease. It discusses the latest research findings and highlight groundbreaking discoveries and innovative methodologies used to study these protein states.Traditionally... the different states of proteins have been defined based on their structures and functions. However, it is becoming increasingly clear that these criteria alone may not be sufficient to capture the complex and multifaceted properties of these molecules. Definitions based on thermodynamics and kinetics are now recognized as potentially more appropriate for comprehensively understanding protein states. Emerging evidence indicates that under physiological conditions, a majority of proteins possess the capability to exist in and transition between the native, droplet, and amyloid states. These distinct states play crucial roles in various cellular functions, influenced significantly by their physicochemical and structural properties. The book also considers the interactions among these states and discusses how their internal organization as individual molecules, as well as their collective organization as molecular assemblies are stabilized. Furthermore, it examines the processes by which these states are formed and the cellular functions associated with each specific state.

  • Transfusion Medicine and Hemostasis

    Clinical and Laboratory Aspects
    • 4th Edition
    • Beth H. Shaz + 3 more
    • English
    **Selected for 2025 Doody’s Core Titles® in Laboratory Medicine**Transfusio... Medicine and Hemostasis: Clinical and Laboratory Aspects, Fourth Edition continues to be the only "pocket-size" quick reference for pathology and transfusion medicine for residents and fellows. It is helpful to all physicians and allied health professionals who order and administer blood components, cellular therapies, specialized factors for hemostatic abnormalities, coagulation testing, and those who consult and care for these often very ill patients. This book is ideal for pathology, medicine, surgery, and anesthesia residents, transfusion, hematology, and anesthesia fellows, and certified and specialized practitioners, as well as medical technologist in transfusion, cellular therapy, hematology, and coagulation. This new edition covers the many new developments that have occurred since the previous edition to include new blood products, new indications, or clinical conditions in which blood products are used. Similarly, new hemostasis testing is introduced as well as new clinical scenarios due the COVID-19 pandemic that area relevant to hemostasis and transfusion medicine. This includes COVID coagulopathy, Vaccine Induced Thrombotic Immune Thrombocytopenia, Pediatric reference range in coagulation testing, Platelet rich plasma and MNC products – CAR-T cells.

  • Diagnosing Musculoskeletal Conditions using Artificial Intelligence and Machine Learning to Aid Interpretation of Clinical Imaging

    • 1st Edition
    • Rakesh Kumar + 3 more
    • English
    Bone deformations can lead to musculoskeletal disorders and negatively impact on individual quality of life. Early and accurate detection of bone deformation is crucial for effective medical intervention. Diagnosing Musculoskeletal Conditions Using Artificial Intelligence and Machine Learning to Aid Interpretation of Clinical Imaging outlines a comprehensive approach that integrates Artificial Intelligence (AI) and Machine Learning (ML) techniques to identify bone deformations promptly and accurately. By leveraging advanced image analysis and pattern recognition, this approach aims to revolutionize the field of orthopedic diagnostics. This book covers challenges, technologies, applications, and future trends of AI and ML in Bone Deformation, addressing advanced and innovative techniques, frameworks, methodologies, and practical implementations of machine learning to get early predictions of Bone deformation. Written by experts in the field for researchers, surgeons, students, and instructors interested in musculoskeletal conditions.

  • Advances in Rhizostomeaen Jellyfish Research

    • 1st Edition
    • Volume 98
    • English
    Advances in Rhizostomeaen Jellyfish Research, Volume 98 in the Advances in Marine Biology series, the latest release in this serial that highlights new advances in the field, includes comprehensive chapters written by an international board of authors.

  • CRISPR Handbook

    Applications, Tools, and Resources
    • 1st Edition
    • Zhi-Yan Du
    • English
    CRISPR Handbook: Applications, Tools and Resources presents a detailed introduction to the CRISPR technology. This handbook summarizes the current CRISPR applications in diverse organisms, shares useful tools for starting a CRISPR experiment, and provides information on software and services for CRISPR technology.Written by an expert in the field of biotechnology and molecular biology of diverse experiment models, including plants, microalgae, and fungi. This handbook will serve as a guide for those who are interested in learning about CRISPR technologies and their applications in research and industry.

  • Health and Climate Change

    Unraveling the Connections
    • 1st Edition
    • Saroj Pachauri + 2 more
    • English
    Health and Climate Change: Unraveling the Connections researches the linkages between climate change and human health as reported from Mexico, the UK, USA, India, Bangladesh, Cameroon, Nigeria, and Cameroon. The book's chapters cover the multidimensional impacts of climate change on various aspects such as habitability, biodiversity, natural resources, and human health. This information from developed and developing countries will be of immense interest to the global audience of researchers, activists, governments, and others.Climate change, one of the greatest challenges of the 21st century, has serious adverse effects on human health. Extreme climate events increase mortality and morbidity, the prevalence of water- and vector-borne diseases, malnutrition, and respiratory diseases. Climate change has serious effects on mental health. Mental health is impacted directly and indirectly resulting in mental illnesses and suicidal mortality. Global heating, due to the increasing greenhouse effect, has disturbed the energetic balance of the Earth and destroyed its fragile climate. It is creating an atmospheric imbalance with toxins that are affecting the human nervous system and, thereby, impacting health.

  • Nanosensors in Healthcare Diagnostics

    • 1st Edition
    • Abhinay Sharma + 3 more
    • English
    Nanosensors in Healthcare Diagnostics examines the role of nanosensors in clinical microbiology, point-of-care sensing, clinical diagnostics, and therapy.This book addresses the concept of nanosensors and their utilization in healthcare diagnostics, and therapy. It covers the principles and mechanisms involved in nanosensor-based diagnostics platforms. It also discusses various approaches and techniques used in the preparation of nanosensors as well as the biomedical application of nanosensors in clinical diagnostics and their significance in the detection, treatment, and management of diseases. This book is a useful reference for researchers, graduate students, and industry professionals studying nanosensors in biological and medical sciences.

  • Genomics, Populations, and Society

    • 1st Edition
    • Dhavendra Kumar + 1 more
    • English
    Genomics, Populations, and Society, a new volume in the Genomic and Precision Medicine in Clinical Practice series, considers the vast and thorny web of ELSI topics in genomics, from bioethics to healthcare applications, healthcare economics, genomic data management, and population dynamics. Emphasis is placed on the impact of rapid genomic advances on ethical, sociocultural and lifestyle dimensions. Healthcare and health economics topics include genomics and digital health, genome editing, and genomics and infectious disease management. Legal issues related to data ownership, equity, access, probity, consent, and confidentiality are also discussed in-depth, along with sociocultural topics such as community engagement, consanguinity, and more.Here, a range of readers from researchers to clinicians, policy administrators, lawyers, economists and social scientists will discover carefully crafted, synthesized discussions on ELSI topics in genomics to power new scientific advances and genomic medicine implementation.

  • Population Genomics in the Developing World

    Concepts, Applications, and Challenges
    • 1st Edition
    • Marlo Möller + 1 more
    • English
    Population Genomics in the Developing World: Concepts, Applications, and Challenges, a new volume in the Translational and Applied Genomics series, provides a comprehensive, up-to-date summary of the field of population genomics in developing countries. This book equips students, researchers, and clinicians with the practical skills and approaches necessary to face the unique challenges and opportunities of practicing population genomics in developing countries. Following a brief foundational overview, more than a dozen authors working in developing nations share applied case studies from the field, including rationale, methods, analysis, and outcomes to reinforce understanding. Key themes across the country-specific chapters include efficient genetic data generation and effective computational and statistical tools to analyze population-level data. This book then discusses clinical interpretation of these data, from direct-to-consumer ancestry testing to translational and applied precision medicine. A final chapter considers the ethical aspects of conducting genomic research in developing countries.

  • Penile Prosthetic Surgery

    Practical Guide to Prosthetic Implant
    • 1st Edition
    • Andrea Cocci + 2 more
    • English
    Penile Prosthetic Surgery provides comprehensive coverage of penile prosthesis surgery. The book thoroughly describes the different types of penile prosthesis and provides step-by-step surgical procedures in diverse patients. Additionally, access to supplemental videos to accompany the procedures provide enhanced learning through the opportunity to see procedures carried out. Content covers the common tips and tricks for successful surgery and presents possible complications with accompanying solutions. Coverage includes full acknowledgement and examinational of the basic research and underling pathological mechanisms that are present in the erectile dysfunction resistant to medical therapy as well as the counselling that patients may need from both the urological and psychological point of view. The book gives a full comprehension of penile prosthesis surgery from multiple viewpoints making it the perfect reference for urologists, andrologists and psychologists.

  • Transplant Oncology

    A Frontier in Multidisciplinary Cancer Care
    • 1st Edition
    • Maen A. Abdelrahim
    • English
    **Selected for 2025 Doody’s Core Titles® in Transplantation Surgery**Transplant Oncology: A Frontier in Multidisciplinary Cancer Care summarizes new and evolving scientific findings and discoveries in the field of cancer and transplants and gives guidance on future directions and related research. With a strong focus on transplant oncology, the book examines new and evolving topics, including the utilization of immunotherapy in special patient populations as well as the clinical updates on new concepts in the field such as using circulating tumor DNA (ctDNA) as a tool for minimal disease detection, surveillance, and treatment response evaluation as well as rejection assessment and detection in transplant patient for oncological indications.Sections cover applications of transplant medicine and surgery in oncology to improve patient survival outcome and quality of life. The book gives insight into anticancer strategies, such as initiating studies in genomics and cancer immunogenomics based on new insights in liver cancer.In addition, it describes how the adoption of surgical transplantation techniques in oncology has improved conventional resection and bridged the gap between tumor and transplant immunology. This is a must have reference for all those that want to be familiar and up-to-date with the dynamic changes in the field including practicing physicians, scientists, and trainees.

  • Mitochondrial Translocases Part B

    • 1st Edition
    • Volume 707
    • English
    Mitochondrial Translocases Part B series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an internation.

  • Balancing a Sauropod

    The Physiology of a Dinosaur
    • 1st Edition
    • Brant E Isakson
    • English
    One completely unexplored area in terms of physiology is the era of dinosaurs—with good reason, they lived over 100 million years ago and we’re left to make inference based on fossilized bones. However, by merging classical, comparative, and extreme physiology and applying it to current paleontological knowledge of dinosaurs, Balancing a Sauropod: The Physiology of a Dinosaur will for the first time begin to provide a sound physiological underpinning for how they may have lived 100 million years ago. Sauropods were the largest land animals to ever walk the earth with an incredible distance from heart to brain, begging the question, how did they maintain blood flow in their brain? Also, the climate sauropods lived in was hypoxic compared to what we live in now, so how did the dinosaurs breathe in the hypoxic Jurassic era? These questions and others expand to multiple fascinating questions the book will dissect in order of organ systems. The topics focus on major organ systems and apply them to potential sauropod physiology. Less emphasis is given to the skeletal system, as that has been discussed extensively in other literature. Each organ system will be discussed in terms of function and current understanding of how they work in a comparative environment. Balancing a Sauropod: The Physiology of a Dinosaur is written at a technical level to both inform the lay reader and provide a sound argument to scientists in the field.

  • Resistance in Hematologic Malignancies and Cancer

    • 1st Edition
    • Volume 22
    • Lucia Messingerova + 1 more
    • English
    Resistance in Hematologic Malignancies and Cancer brings together the molecular, cellular, and biochemical basis/principles of various mechanisms of resistance to treatment in hematologic malignancies.Even though main mechanisms of resistance are the same in different types of tumours there are specific signalling pathways involved in resistance in hematological malignancies and of course specific treatmentsIn 11 chapters, Resistance in Hematologic Malignancies and Cancer describes the development of treatment resistance in hematological malignancies, the role of MiRNA in resistance, the role of the immune system in resistance prediction, as well as the latest knowledge from clinical research.It gives insight in the complex information about different mechanisms linkage in final loss of cell sensitivity to drug treatment, the orientation in metabolic pathways that could be involved in depressed leukemia cell resistance to drugs and gives information about causes of drug resistance in leukemia cells.By the multidisciplinary approach of the processing this book is a valuable resource for both health professionals, scientists and researchers, health practitioners, students, but will also enable members of the general professional public to orientate themselves in issues that are not directly in their area of expertise

  • Molecular Pathway Analysis Using High-Throughput OMICS Molecular Data

    Analysis of molecular pathway composition, architecture, and activation using high-throughput genomic, epigenetic, transcriptomic, proteomic, and metabolomic data
    • 1st Edition
    • Anton Buzdin
    • English
    The field molecular pathway analysis evolves rapidly, and many progressive methods have recently been discovered. Molecular Pathway Analysis Using High-Throughput OMICS Data contains the largest collections of molecular pathways. For the first time, guidelines on how to do genomic, epigenetic, transcriptomic, proteomic, and metabolomic data analysis in real-world research practice are given. Molecular Pathway Analysis Using High-Throughput OMICS Molecular Data also focuses on the pathway analysis applications for solving tasks in biotechnology, pharmaceutics, and molecular diagnostics ​​It demonstrates how pathway analysis can be applied for the research and treatment of chronic and acute diseases, for next-generation molecular diagnostics, for drug design and preclinical testing; relevant real-world examples, molecular tests, and web resources will be reviewed in-depth.​ ​​The book shows a tendency of erasing the borders between chemistry, physics, informatics, mathematics, biology, and medicine by means of novel research approaches and instruments, providing a truly multidisciplinary approach.

  • Customized Ob/Gyn Management for Diverse Populations

    • 1st Edition
    • Gloria Bachmann + 1 more
    • English
    Customized Ob/Gyn Management for Diverse Populations provides tailored options of management for optimal clinical care of the major preventive and interventive Ob/Gyn issues. Case scenarios highlight and discuss the need for customized care and inclusive protocols that depend on each woman's race, gender, sexual orientation, culture and socio-economic factors. As health disparities adversely affect groups of people who have systematically experienced greater social and economic obstacles to health based on their racial or ethnic group, socioeconomic status, gender, sexual orientation or other characteristics historically linked to discrimination or exclusion, this book provides a welcomed resource.The book highlights the fact that in order to change the current scenario the health care community needs more information and awareness of health care data regarding diverse groups, population health and well-being.

  • Colorectal Cancer Treatment Resistance

    Mechanisms, Insights, Advances, and Solutions
    • 1st Edition
    • Zodwa Dlamini
    • English
    Colorectal Cancer Treatment Resistance: Mechanisms, Insights, Advances and Solutions provide insights, knowledge, and potential solutions for healthcare professionals, researchers, and individuals affected by colorectal cancer. The book discusses innovative therapies, personalized medicine, and the latest scientific advancements in the field, all aimed at enhancing the effectiveness of treatment and improving the prognosis for colorectal cancer patients. It elucidates on the broader context of cancer research and treatment strategies that have the potential to impact the overall approach to managing colorectal cancer and, by extension, other types of cancer that may exhibit similar resistance challenges.By studying and addressing resistance mechanisms, researchers and healthcare professionals can work towards improving patient outcomes and the overall quality of cancer care.

  • Mitochondrial Translocases Part A

    • 1st Edition
    • Volume 706
    • English
    Mitochondrial Translocases Part A series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Human and Animal Microbiome Engineering

    • 1st Edition
    • Dharumadurai Dhanasekaran + 2 more
    • English
    Human and Animal Microbiome Engineering provides both basic and detailed information about microbiome engineering for the health enhancement of humans and animal populations. The book provides updated information about current research topics in this emerging field, including microbiome gene therapy, engineered probiotics, and smart living biotic machines for the release of therapeutics. The book is divided into 4 sections covering microbiome engineering application with a focus on future perspectives in human health and enhancement; microbiome engineering in human health and disease including real-world case studies; animal microbiome engineering essentials; and microbiome engineering for livestock improvement.This is the perfect reference for researchers and scientists to further explore the relationship between host and microbiome and discover novel ideas about the concepts of microbiome engineering in the health enhancement of humans and animal populations.

  • Pathophysiological Aspects of Proteases in Cancer

    • 1st Edition
    • Sajal Chakraborti + 2 more
    • English
    Pathophysiological Aspects of Proteases in Cancer provides a comprehensive overview of the multifaceted field of proteases in the cellular environment and focuses on the recently elucidated functions of complex proteolytic systems in physiology and pathophysiology. The book both gives insights on the general aspects of the role of proteases in cancer, their role as diagnostics and prognostics biomarkers, their impact on chemoresistance, and the future cutting-edge technologies like cocktail therapies and Cyber Knife technology. Given the breadth and depth of information covered in the respective contributions, the book will be immensely useful for researchers in oncology and working to identify targets for drug development.Multidis... in scope, the book bridges the gap between fundamental and translational research, with applications in the biomedical and pharmaceutical industry, making it a thought-provoking read for basic and applied scientists engaged in biomedical research.

  • Genetic Disease Discovery and Therapeutics

    • 1st Edition
    • Moyra Smith
    • English
    **Selected for 2026 Doody's Core Titles in Clinical Genetics**Genetic Disease Discovery and Therapeutics presents information on the methods used to determine how specific gene defects influence pathology and phenotype and to review novel therapeutic approaches designed for the treatment of specific genetic and genomic disorders.This book investigates methodologies applied to the characterization of downstream functional effects of specific gene mutations associated with altered phenotypes and clinical disease. It documents evidence of how specific mutations influence pathology and lead to disease manifestations. This book also reviews information on therapeutic approaches that could potentially be applied in diseases due to gene defects. Genetic Disease Discovery and Therapeutics is a valuable reference for scientists and graduate students involved in laboratory research related to genetics, physiology, pathology, and pharmacology as well as clinicians who encounter patients with genetic disorders.

  • Emery and Rimoin’s Principles and Practice of Medical Genetics and Genomics

    Developmental Disorders
    • 7th Edition
    • Reed E. Pyeritz + 2 more
    • English
    **Selected for 2026 Doody's Core Titles as an Essential Purchase in Clinical Genetics**For decades, Emery and Rimoin’s Principles and Practice of Medical Genetics and Genomics has served as the ultimate resource for clinicians integrating genetics and genomics into medical practice. With detailed coverage in contributions from more than 250 of the world’s most trusted authorities in medical genetics and a series of 11 volumes available for individual sale, the Seventh Edition of this classic reference includes the latest information on seminal topics such as prenatal diagnosis, genome sequencing, public health genetics, genetic counseling, and management and treatment strategies to complete its coverage of this growing field for students, health providers, and researchers involved in the care of patients with genetic conditions, and increasingly, all areas of health and disease. This comprehensive yet practical resource emphasizes theory and research fundamentals related to the applications of medical genetics and genomics across the full spectrum of inherited disorders and applications to medicine more broadly.In this volume, leading physicians and researchers thoroughly examine medical genetics and genomics as applied to developmental disorders, as well as genetic conditions that affect hearing and vision. Here genetic researchers, students, and health professionals will find new and fully revised chapters on human developmental genetics, disorders affecting craniofacial development, chromosomal abnormalities, including aneuploidies and structural abnormalities, hereditary hearing impairment, and various genetic conditions of the eye.With regular advances in genomic technologies propelling precision medicine into the clinic, Emery and Rimoin’s Principles and Practice of Medical Genetics and Genomics, Seventh Edition bridges the gap between high-level molecular genetics and practical application and serves as an invaluable clinical tool for health professionals and researchers.

  • γδ T Cell Cancer Immunotherapy

    Evidence-Based Perspectives for Clinical Translation
    • 1st Edition
    • Marta Barisa
    • English
    γδ T Cell Cancer Immunotherapy: Evidence-Based Perspectives for Clinical Translation sets out and critically discusses the current clinical and relevant preclinical γδ T cell immunotherapy landscape.In five chapters, field experts discuss the challenges facing γδ T cell oncoimmunotherapy, propose solutions, and map next steps.Particular attention is given to summarizing our understanding of the complex, translationally relevant human γδ T cell biology, the evidence basis for designing γδ T cell combination trials and data-driven perspectives on what is known—and what isn’t—about γδ T cell therapeutic persistence. Various perspectives are provided on how issues of cytotoxic effector function, functional exhaustion, and cytokine addiction can be mitigated using gene engineering.A chapter is dedicated to the systematic review of all γδ T cell immunotherapy trials to date, and the cell therapy products that were used in these trials. The final chapter discusses allograft persistence-enhancem... techniques in the context of γδ T cell therapy, covering lymphodepleting chemotherapy and synthetic stealth engineering.γδ T Cell Cancer Immunotherapy: Evidence-Based Perspectives for Clinical Translation gives an updated and comprehensive insight into the current state of γδT cell immunotherapy, which is of interest to existing translational γδ T cell specialists, the proliferating range of academic scientists and commercial scientists entering the field, as well as clinicians who may encounter γδ T cell immunotherapy in the clinic, or are wishing to familiarize themselves with noncanonical lymphocyte immunotherapy.

  • Marine Molecules from Algae and Cyanobacteria

    Extraction, Purification, Toxicology and Applications
    • 1st Edition
    • Paz Otero Fuertes + 1 more
    • English
    The marine environment is a rich but underexploited source of commercially interesting natural products with different applications. Several marine organisms, such as seaweeds, microalgae, sponges, cyanobacteria, ascidians, and fungi, are sources of natural valuable molecules. These chemical compounds range from small molecules and enzymes to highly complex secondary metabolites that show bioactivities in physiological systems. It is thus of great importance to collect information concerning the discovery of these molecules and their characterization and relation to human diseases. Gathering data about novel technologies and sources to obtain and isolate such as precious molecules as well as new applications for them is extremely appreciated in the chemical field. It is very useful for chemists to obtain these molecules with high purity to be used as analytical standards to calibrate the chromatography equipment. Many of these compounds are not commercially available, so the isolation methods of these molecules from microalgae, seaweeds, and cyanobacteria is a challenging task. The availability of some marine molecules has been a long-term problem due to the difficulty of their synthesis. Because of the complexity of their structure, the total synthesis has been shown to be difficult. Developing protocols to obtain reference standards from natural sources has shown satisfactory results in the chemical industry. Marine Molecules From Algae and Cyanobacteria addresses these topics, highlighting fundamentals of biomolecules, their roll in living organism, structure elucidation, sources, important characteristics, and the industrial applications of these biomaterials for educational (academic) as well as industrial purposes. This book covers all methodologies used in the search of marine natural products: screening of marine molecules by chemical methods like HPLC, LC-MS/MS, the isolation of high-value compounds with biotechnological potential, discovery of new molecules, and the optimization of green extraction procedures of these molecules, such as supercritical fluid extraction and pressurized solvent extraction, and other alternative chemical techniques applied in the exploration for marine compound.

  • Protocols in Biochemistry and Clinical Biochemistry

    • 2nd Edition
    • Buddhi Prakash Jain + 2 more
    • English
    Protocols in Biochemistry and Clinical Biochemistry, second edition, offers clear, applied instruction in fundamental biochemistry methods and protocols, from buffer preparation to nucleic acid purification, protein, lipid, carbohydrate, and enzyme testing, and clinical testing of vitamins, glucose, and cholesterol levels, among other diagnostics. Each protocol is illustrated with step-by-step instructions, labeled diagrams, and color images, as well as a thorough overview of materials and equipment, precursor techniques, safety considerations and standards, analysis and statistics, alternative methods, and troubleshooting, all to support a range of study types and clinical diagnostics. This fully revised edition has been expanded and enriched to feature 100 protocols, as well as chapter key term definitions and worked examples. All-new protocols added to this edition include identification of lipids by TLC, lipid per oxidation measurement by thiobarbituric acid assays, determination of serum amylase, catalase activity assay, superoxide dismutase assay, qualitative analysis of plant secondary metabolites, qualitative analysis of photochemicals, quantitative estimation of secondary metabolites, estimation of chlorophyll contents, and starch determination, among others. Each protocol is written to help researchers and clinicians easily reproduce lab methods and ensure accurate test results.

  • Extracellular Vesicles from Basic Research to Clinical Applications

    • 1st Edition
    • Volume 94
    • English
    Extracellular Vesicles from Basic Research to Clinical Applications, Volume 94 covers theses lipid bilayer particles containing proteins, glycoproteins, mRNA, other small RNA species, and lipids formed and released by various pathogens. Chapters in this update include Extracellular Vesicles release from protozoa parasite and animal model, EVs from parasite and biomarkers, Translational Medicine – Use of EVs as therapy, EVs and viruses and their interaction with cells, EVs and Toxoplasma gondii, EVs and Fungi, Biogenesis of EVs in parasites, Extracellular vesicles, EVs and Leishmania, EVs in neuropsychiatry, EVs and Bacteria.Other sections cover EVs and sleep deprivation, EVs and cancer, Extracellular vesicles and methods to isolation, purification, and characterization.

  • Translational Urology

    • 1st Edition
    • Anthony Atala + 3 more
    • English
    Translational Urology covers the principles of evidence-based medicine and applies these principles to the design of translational investigations. The reader will come to fully understand important concepts, including case-control study, prospective cohort study, randomized trial, and reliability study. Medical researchers will benefit from greater confidence in their ability to initiate and execute their own investigations, avoid common pitfalls in urology, and know what is needed for successful collaboration. Further, this title is an indispensable tool in grant writing and funding efforts.This practical, straightforward approach helps the aspiring investigator navigate challenging considerations in study design and implementation. The book provides valuable discussions of the critical appraisal of published studies in urology, allowing the reader to learn how to evaluate the quality of such studies with respect to measuring outcomes and to make effective use of all types of evidence in patient care.

  • Next Generation eHealth

    Applied Data Science, Machine Learning and Extreme Computational Intelligence
    • 1st Edition
    • Miltiadis D. Lytras + 3 more
    • English
    Next Generation eHealth: Applied Data Science, Machine Learning and Extreme Computational Intelligence discusses the emergence, the impact, and the potential of sophisticated computational capabilities in healthcare. This book provides useful therapeutic targets to improve diagnosis, therapies, and prognosis of diseases, as well as helping with the establishment of better and more efficient next-generation medicine and medical systems. Machine learning as a field greatly contributes to next-generation medical research with the goal of improving medicine practices and medical Systems. As a contributing factor to better health outcomes, this book highlights the need for advanced training of professionals from various health areas, clinicians, educators, and social professionals who deal with patients. Content illustrates current issues and future promises as they pertain to all stakeholders, including informaticians, professionals in diagnostics, key industry experts in biotech, pharma, administrators, clinicians, patients, educators, students, health professionals, social scientists and legislators, health providers, advocacy groups, and more. With a focus on machine learning, deep learning, and neural networks, this volume communicates in an integrated, fresh, and novel way the impact of data science and computational intelligence to diverse audiences.

  • The Charnolosome as a Novel Nanothereranostic Biomarker

    Overcoming Future Challenges in Medicine
    • 1st Edition
    • Sushil Sharma
    • English
    The Charnolosome as a Novel Nanothereranostic Biomarker: Overcoming Future Challenges in Medicine provides an overview of the charnolosome and its potential as a biomarker of cell injury. Based on the author’s original discovery of the charnoly body in the developing, undernourished rat cerebellar Purkinje neurons, this book delves into the potential for utilizing this mitochondria and lysosomal-derived intracellular organelle as a nanotheranostic biomarker to prevent and cure various diseases.The book discusses the cellular, molecular, genetic, and epigenetic mechanisms of charnolosomes and charnolosome-derived nano-vesicles. It also investigates the molecular mechanisms underlying auto-inflammatory, autoimmune, and infectious diseases resulting from their compromised mitochondrial bioenergetics, and the potential use of the charnolosome in preventing and curing such conditions.

  • Artificial Intelligence in Biomedical and Modern Healthcare Informatics

    • 1st Edition
    • M. A. Ansari + 4 more
    • English
    Artificial Intelligence in Biomedical and Modern Healthcare Informatics provides a deeper understanding of the current trends in AI and machine learning within healthcare diagnosis, its practical approach in healthcare, and gives insight into different wearable sensors and its device module to help doctors and their patients in enhanced healthcare system.The primary goal of this book is to detect difficulties and their solutions to medical practitioners for the early detection and prediction of any disease.The 56 chapters in the volume provide beginners and experts in the medical science field with general pictures and detailed descriptions of imaging and signal processing principles and clinical applications.With forefront applications and up-to-date analytical methods, this book captures the interests of colleagues in the medical imaging research field and is a valuable resource for healthcare professionals who wish to understand the principles and applications of signal and image processing and its related technologies in healthcare.

  • Predictive Analytics using MATLAB(R) for Biomedical Applications

    • 1st Edition
    • L. Ashok Kumar
    • English
    Predictive Analytics using MATLAB(R) for Biomedical Applications is a comprehensive and practical guide for biomedical engineers, data scientists, and researchers on how to use predictive analytics techniques in MATLAB(R) for solving real-world biomedical problems. The book offers a technical overview of various predictive analytics methods and covers the utilization of MATLAB(R) for implementing these techniques. It includes several case studies that demonstrate how predictive analytics can be applied to real-world biomedical problems, such as predicting disease progression, analyzing medical imaging data, and optimizing treatment outcomes.With a plethora of examples and exercises, this book is the ultimate tool for reinforcing one’s knowledge and skills.

  • Advances in Marine Biology

    • 1st Edition
    • Volume 97
    • English
    Advances in Marine Biology, Volume 97, the latest release in this serial that highlights new advances in the field, including comprehensive chapters written by an international board of authors.

  • Tyrosinase

    • 1st Edition
    • Volume 56
    • English
    Tyrosinase, Volume 56 in The Enzymes series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Overview on tyrosinases (genetics, molecular biology, phylogenetic relationship), Catalytic mechanism of tyrosinases, Structural characterization of tyrosinases, Assay methods of tyrosinase activity and inhibition, Natural products as tyrosinase inhibitors, Drug design of tyrosinase inhibitors, Peptide and peptidomimetic tyrosinase inhibitors, Computational studies of tyrosinase inhibitors, Bacterial tyrosinases and their inhibitors, and Biomedical applications of tyrosinases and tyrosinase inhibitors.

  • Artificial Intelligence and Multimodal Signal Processing in Human-Machine Interaction

    • 1st Edition
    • Abdulhamit Subasi + 2 more
    • English
    Artificial Intelligence and Multimodal Signal Processing in Human-Machine Interaction presents an overview of an emerging field that is concerned with exploiting multiple modalities of communication in both Artificial Intelligence and Human-Machine Interaction. The book not only provides cross disciplinary research in the fields of multimodal signal acquisition and sensing, analysis, IoTs (Internet of Things), Artificial Intelligence, and system architectures, it also evaluates the role of Artificial Intelligence I in relation to the realization of contemporary Human Machine Interaction (HMI) systems.Readers are introduced to the multimodal signals and their role in the identification of the intended subjects, mental state and the realization of HMI systems are explored, and the applications of signal processing and machine/ensemble/dee... learning for HMIs are assessed. A description of proposed methodologies is provided, and related works are also presented. This is a valuable resource for researchers, health professionals, postgraduate students, post doc researchers and faculty members in the fields of HMIs, Brain-Computer Interface (BCI), Prosthesis, Computer vision, and Mental state estimation, and all those who wish to broaden their knowledge in the allied field.

  • The Kidney of the Critically Ill Pregnant Woman

    • 1st Edition
    • Jorge Hidalgo + 2 more
    • English
    The Kidney of the Critically Ill Pregnant Woman is a volume in the Critical Care in Obstetrics series. It’s a novel reference to educate physicians, nurses, and all allied healthcare personnel caring for pregnant women with kidney compromise. The authors have gathered the best evidence-based material explicitly focused on severe kidney complications in pregnant patients and postpartum. Among the chapters, the book covers medical-surgical complications that any patient can present, such as acute kidney injury during pregnancy, kidney disease, and hypertension complications specific to pregnancy.

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