Skip to main content
Elsevier

Books in Immunology

Elsevier's Immunology collection equips researchers with valuable insights to address the complexities of the immune system and its role in health and disease, offering original research, insightful analysis, and current theory on diagnosing, managing, and advancing treatments for allergies, asthma, and immunologic disorders.

  • Cumulative Subject Index

    • 1st Edition
    • Volume 45
    • English
    Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular bases of drug action, both applied and experimental. For easy reference, this volume provides a cumulative subject index covering Volumes 25-44.

  • Advances in Immunology

    • 1st Edition
    • Volume 70
    • English
    Advances in Immunology presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.

  • Bacterial Pathogenesis

    • 1st Edition
    • Volume 27
    • English
    Established almost 30 years ago, Methods in Microbiology is the most prestigious series devoted to techniques and methodology in the field. Now totally revamped, revitalized, with a new format and expanded scope, Methods in Microbiology will continue to provide you with tried and tested, cutting-edge protocols to directly benefit your research.

  • Encyclopedia of Immunology

    • 2nd Edition
    • Peter J. Delves + 1 more
    • English
    With more than 700 expert authors from 22 different countries, the Encyclopedia of Immunology, Second Edition is the largest comprehensive reference source of current immunological knowledge available. It provides a broad scope and high level of expertise to the many aspects of the field of immunology and related areas, including microbiology, virology, and parasitology. Arranged into 31 subject areas with extensive cross-referencing and subject indexes in each volume, the Encyclopedia is easy-to-use for virtually any researcher, regardless of his or her field. Concise definitions of the subject area also introduce each entry. The Second Edition includes timely and thorough updates for all articles from the First Edition, more than 60 new entries, a glossary of immunological terms in each volume, a total of 500 figures and tables, and new color plates sections.

  • Advances in Immunology

    • 1st Edition
    • Volume 69
    • English

  • Handbook of Vertebrate Immunology

    • 1st Edition
    • Paul-Pierre Pastoret + 3 more
    • English
    This unique book provides a comprehensive and comparative guide to the immune systems of major vertebrate species, including domestic and wild animals of veterinary or medical interest, fish and amphibia. Data in this essential reference work has been compiled by world-renowned editors and an international group of authors. For each species, the information is presented in a structured 'user-friendly' format allowing easy cross reference and comparison between the various species.This book will be considered the definitive reference work on vertebrate immunology and will be essential for scientists and professionals working in Immunology, Vaccinology or with Animal Models, for students of Veterinary or Human Medicine, Biology and researchers in Comparative Medicine and Physiology.

  • Immunology of Infection

    • 1st Edition
    • Volume 25
    • English
    Established for almost 30 years, Methods in Microbiology is the most prestigious series devoted to techniques and methodology in the field. Now totally revamped, revitalized, with a new format and expanded scope, Methods in Microbiology will continue to provide you with tried and tested, cutting-edge protocols to directly benefit your research. Immunology of Infection, edited by two of the foremost figures in the field, presents the most appropriate, up-to-date techniques in the detail you require. The layout is structured for ease of reference, and the volume will be essential reading for all researchers working in microbiology, immunology, virology, mycology, and parasitology.The new volume provides a carefully selected collection of immunological techniques for the microbiologist wishing to study host-pathogen relationships in vivo and in vitro. This multi-authored book has succeeded in bringing together experts from various fields of molecular and cellular immunology who provide ready-to-use recipes for the ex vivo and in vitro analysis of anti-infective immunity.

  • Cytokines

    • 1st Edition
    • Anthony R. Mire-Sluis + 1 more
    • English
    This book provides comprehensive coverage of the cytokines from a pharmacological approach. The chapters are presented in a consistent format allowing easy cross-reference, with sample diagrams and a summary table of essential facts for each chapter at the end of the book.Cytokines is unique in stressing cytokine biology and the application of research data to provide disease therapy. With 33 detailed and up-to-date chapters about individual cytokines, this comprehensive reference will provide both clinicians and researchers in immunology and pharmacology with invaluable information.

  • Advances in Immunology

    • 1st Edition
    • Volume 68
    • English

  • Advances in Pharmacology

    • 1st Edition
    • Volume 44
    • English
    Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular bases of drug action, both applied and experimental.

  • Emerging Infections

    • 1st Edition
    • Volume 1
    • English
    Emerging Infections is the first volume of the new Biomedical Research Reports Series, which will provide annual updates on hot topics of interest to a broad spectrum of the biomedical research community. This book provides state-of-the-art reviews of new and reemerging bacterial, viral, and parasitic infections, their life cycles, host defense evasion strategies, and clinical features. It includes the history of infectious disease outbreaks, population and evolutionary biology of human pathogens, and current epidemiological models that describe how ecological and demographic changes produce new epidemics.

  • Glycoproteins II

    • 1st Edition
    • Volume 29
    • J. Montreuil + 2 more
    • English
    Part II of this excellent work covers proteoglycans and mucins and deals with many more examples of glycoprotein function. It also covers glycoproteins from four more species (slime mold, snails, fish, batracians).The content of the volume is very comprehensive in that most contributors are focussed on discussing, in depth, the wealth of most recent advances in their field, referring to previous reviews of older work for background information. This method effectively produces a very wide subject coverage in a smaller number of chapters/volumes. The volume is an important information source for all glycobiologist researchers (senior investigators, post-doctoral fellows and graduate students), and as a good, comprehensive, reference text for scientists working in the life sciences.

  • Idiotypes in Medicine: Autoimmunity, Infection and Cancer

    • 1st Edition
    • R.C. Kennedy + 2 more
    • English
    This is the most comprehensive review of the idiotypic network available. All the current knowledge of idiotypes of the various antibodies is incorporated in this volume. The pathogenic role of idiotypes in autoimmunity and cancer is reviewed in depth. The therapeutic part focusses on harnessing anti-idiotypes for treating autoimmunological disorders, and on the employment of idiotypes for vaccines in cancer and infectious diseases, as well as explaining the manipulation of the idiotypic network in autoimmunity and cancer idiotypes and vaccines.

  • Advances in Immunology

    Cumulative Subject Index, Volumes 37-65
    • 1st Edition
    • Volume 67
    • English

  • Chemokine Receptors

    • 1st Edition
    • Volume 288
    • John N. Abelson + 1 more
    • English
    Chemokines are major mediators of immune cells and are involved in a wide range of proinflammatory human diseases, including rheumatoid arthritis, multiple sclerosis, and organ transplant rejection. It has recently been discovered that their receptors are involved in HIV infection. The characterization of these molecules and their receptors is thus of primary importance in understanding a number of human diseases and infections. This volume and its companion Volume 287 Chemokines provide comprehensive experimental protocols used in this field of research.

  • Chemokines

    • 1st Edition
    • Volume 287
    • John N. Abelson + 1 more
    • English
    Chemokines are major mediators of immune cells and are involved in a wide range of proinflammatory human diseases, including rheumatoid arthritis, multiple sclerosis, and organ transplant rejection. It has recently been discovered that their receptors are involved in HIV infection. The characterization of these molecules and their receptors is thus of primary importance in understanding a number of human diseases and infections. This volume and its companion Volume 288 on Chemokine Receptors provide comprehensive experimental protocols used in this field of research.

  • Advances in Immunology

    • 1st Edition
    • Volume 65
    • English
    Ig A DeficiencyThe Role of Cellular Immunity in Protection against HIV InfectionMouse Mammary Tumour Virus: Immunological Interplays between Virus and HostThe Transporter Associated with Antigen ProcessingNF-kB in cytokine gene expressionNF-kB as a target for immunosuppressive and anti-inflammatory molecules

  • The Leucocyte Antigen Factsbook

    • 2nd Edition
    • A. Neil Barclay + 5 more
    • English
    A volume in the popular FactsBook Series, the First Edition of The Leucocyte Antigen FactsBook was hugely successful. The new Second Edition has been completely revised, updated, and expanded by 65% to include new findings and up-to-date key references. The introductory chapters have also been updated, especially in terms of nomenclature, the role of the World Wide Web, and new structural data. The Leucocyte Antigen FactsBook, Second Edition contains more than 200 entries, with approximately 70 new entries, on all the molecules specifically expressed in the surface of cells of the haematopoietic system, including all characterized CD antigens, antigen receptors, MHC antigens, adhesion molecules, and cytokine receptors. This FactsBook will be of enormous value to immunologists, cell biologists, biochemists, and endocrinologists.

  • Immunoregulation in Health and Disease

    Experimental and Clinical Aspects
    • 1st Edition
    • Miodrag L. Lukic + 3 more
    • English
    Immunoregulation in Health and Disease, edited by Lukic, Colic, Mostarica-Stojkovic and Cuperlovic is a multi-authored volume covering the field of Immunoregulation, and will be essential reading for all researchers working in Immunology. Each section includes at least 10 papers contributed by experts from around the World, and covers in detail the wealth of knowledge relating to immunoregulation, both in health and disease. This book will provide an invaluable overview of immune system behaviour.

  • The Chemokine Factsbook

    Ligands and Receptors
    • 1st Edition
    • Krishna Vaddi + 2 more
    • English
    How do you keep track of basic information on the proteins you work with? Where do you find details of their physicochemical properties, amino acid sequences, gene organization? Are you tired of scanning review articles, primary papers and databases to locate that elusive fact? The Academic Press FactsBook series will satisfy scientists and clinical researchers suffering from information overload. Each volume provides a catalog of the essential properties of families of molecules. Gene organization, amino acid sequences, physicochemical properties, and biological activity are presented using a common, easy-to-follow format. Taken together they compile everything you want to know about proteins but are too busy to look for. The Chemokine FactsBook contains more than 40 entries on chemokines, and chemokine receptors from human or other origin, including IL-8, MCP-1, C5-a, RANTES, Lymphotactin, and CC CKR-1. The text provides information on tissue sources, target cells, physicochemical properties, transcription factors, regulation of expression in disease, receptor-binding characteristics, gene structure and location, amino acid sequences, and accession numbers and references.

  • Immunobiology

    • 1st Edition
    • Volume 6
    • Edward Bittar
    • English
    As this volume demonstrates, immunobiology is a young science which is undergoing explosive growth. Judged by results, it is already an elaborate discipline which cuts across every other area in biomedical research and even has its own vocabolary (e.g., the "veto" effect). Rather than inculcate the habit of superficial learning by having the student go through a maze of details, we have sought to gather together sixteen essays that range from T-cells to psyhoneuroimmunology... This is keeping with the growing understanding that the student is expected to read and think far more for herself/himself.Next to nothing is known about innate immunity. However, recent evidence suggests that collectins might bridge the gap between innate immunity and specific clonal immune responses. Collectins are soluble effector proteins that include serum mannose-binding protein, and lung surfactants A and D. They are considered to be ante-antibodies.

  • Antigen Binding Molecules: Antibodies and T-Cell Receptors

    • 1st Edition
    • Volume 49
    • English
    Topics Covered Include: X-ray crystallography of ligands. Catalytic antibodies. Nature of the antigen. Antibody binding sites. Maturation of the immune response. Computational biochemistry of antibodies and T-cell receptors. Antigen-specific T-cell receptors and their reactions.

  • A History of Transplantation Immunology

    • 1st Edition
    • Leslie Brent
    • English
    Those entering the field of transplantation are frequently unaware of the topics historical roots and even of the background on which modern discoveries in tolerance, histocompabatibility antigens, and xenotransplantation are based. A History of Transplantation Immunology is an account, written by one of the founding fathers of the field, of how tissue and organ transplantation has become one of the most successful branches of late 20th century medicine. The book helps place the work of contemporary scientists into its proper context and makes fascinating reading for immunologists in all stages of their career.

  • Advances in Immunology

    • 1st Edition
    • Volume 63
    • English
    Praise for the Series:"The series which all immunologists need."--The Pharmaceutical Journal"Advances in Immunology must find itself among the most active volumes in the libraries of our universities and institutions."--Scie... a permanent place in biomedical libraries as an aid in research and in teaching."--Journal of Immunological Methods

  • Advances in Cancer Research

    • 1st Edition
    • Volume 70
    • English
    Volume 70 begins with two "Foundations in Cancer Research" articles, a staple of the Advances in Cancer Research series. The first article by Michael Stoker presents a review of some of the early advances made by cancer cell biology researchers. The second article by Emmanuel Farber describes the methods by which researchers delineate the phenotype of cells and ways to alter these phenotypes to prevent or delay carcinomas. Chidambaram and Dean illustrate the tumors and associated malformations of nevoid basal cell carcinoma. Koli and Keski-Oja review the effects of how transforming growth factor-b regulates cell proliferation, differentiation, and morphogenesis and its regulation by the steroid hormone superfamily. Jean-Marc Lemaitre and colleagues discuss the involvement of protooncogenes in the control of the cell cycle and embryonic development with specific attention paid to c-Myc expression and c-Myc function. A review of the various studies involving tumor-infiltrating lymphocytes and their possible role in cancer prevention is presented by Steven Rosenberg and co-workers. Finally, Bruce Ponder and Darrin Smith review the genetic and biological aspects of multiple endocrine neoplasia type-2 syndromes and the phenotypes associated with ret mutations.

  • Mucosal Vaccines

    • 1st Edition
    • Hiroshi Kiyono
    • Hiroshi Kiyono + 2 more
    • English
    This comprehensive, authoritative treatise covers all aspects of mucosal vaccines including their development, mechanisms of action, molecular/cellular aspects, and practical applications. The contributing authors and editors of this one-of-a-kind book are very well known in their respective fields. Mucosal Vaccines is organized in a unique format in which basic, clinical, and practical aspects of the mucosal immune system for vaccine development are described and discussed. This project is endorsed by the Society for Mucosal Immunology.

  • Glycoproteins and Disease

    • 1st Edition
    • Volume 30
    • J. Montreuil + 2 more
    • English
    The elucidation during the latter half of the 20th century of the mechanisms by which information flows from nucleic acids to proteins has completely changed the face of biological research. Many diseases are caused by abnormalities in control mechanisms which are not immediately essential for life itself but which maintain the normal social behavior of differentiated cells in multicellular organisms. The complex sugar chains of glycoproteins and glycolipids are believed to play important roles in the control of cellular functions and in recognition between the cell and its cellular and fluid environment. Investigations into the abnormalities of complex sugar chain assembly are expected to yield an important new underatanding of the etiology and pathogenesis of human diseases. This volume discusses several representative diseases which emphasize the current status of glycopathology, and will stimulate further research in this exciting field.

  • Essentials of Mucosal Immunology

    • 1st Edition
    • Martin F. Kagnoff + 1 more
    • English
    Essentials of Mucosal Immunology presents basic concepts as well as new and exciting advances in mucosal immunology and inflammation, the development of mucosal vaccines, and the role of the immune system in mucosal disease. Specific chapters highlight novel approaches to the treatment of autoimmune disease, including the use of oral tolerance; approaches to and vectors for new vaccines; and current concepts in mucosal inflammation and its role in inflammatory bowel disease and ulcer disease.

  • Autoantibodies

    • 1st Edition
    • J.B. Peter + 1 more
    • English
    This volume is THE definitive, completely up-to-date, reference work for ALL researchers and clinicians working in autoimmunity.Up-to-D... This is a timely critical review of more than 100 autoantibodies by leading experts in their respective fields, and includes many recent references.Internati... Experts: The 120 Chapters have been written by the top international cadre of authors who have provided structured, expert contributions.Compre... A total comprehensive perspective on the processes which induce, inhibit or otherwise affect autoantibodies in humans.Useful to Researchers and Clinicians: Chapters generally include methods of detection, pathogenic role, factors in pathogenicity and genetics as well as clinical utility with disease associations and frequencies.

  • Immunoassay

    • 1st Edition
    • Eleftherios P. Diamandis + 1 more
    • English
    Immunoassays are among the most powerful and sensitive technologies now available for patient diagnosis and monitoring. This book is an indispensable guide to information on the theory and practice of immunoassays. It discusses the scientific basis of these technologies in a logical, organized, and heuristic manner and provides protocols for specific assays. The contents of this unique book are balanced among theory, practical issues, quality control, automation, and subspecialty areas, making it ideal for health science students, laboratory scientists, and clinicians.

  • Advances in Cancer Research

    • 1st Edition
    • Volume 68
    • English
    Volume 68 of Advances in Cancer Research continues the tradition of publishing up-to-date reviews and "hot" topics in cancer research. This volume begins with a "Foundations in Cancer Research" article by Harald zur Hausen that reviews his years of research on the idea that cancer can be triggered by infection. The structure and function of the cytokine receptor superfamily and its association with leukemias are discussed in depth by James Ihle. Marcia Hall and Gordon Peters review the evidence indicating that genetic abnormalities hinder the function of certain cyclins and their inhibitors. The most widely studied protooncogene, c-myc, is reviewed by Marie Henriksson and Bernhard Lüscher; the chapter focuses on the function of c-myc as a transcription factor rather than on the effects of gene translocation and activation on malignancies. Ham Werner and Derek LeRoith present data on the role that insulin-like growth factors play on cell growth and regulation. In the final chapter, Olli-P. Kallioniemi and Tapio Visakorpi investigate the field of prostate cancer and, more importantly, the biological reason and natural history behind the growth of this cancer.

  • Advances in Immunology

    • 1st Edition
    • Volume 61
    • English
    "The series which all immunologists need."--The Pharmaceutical Journal"Advances in Immunology must find itself among the most active volumes in the libraries of our universities and institutions."--Scie... a permanent place in biomedical libraries as an aid in research and in teaching"--Journal of Immunological Methods"A provocative and scholarly review of research"--Journal of the American Medical Association"Provides an extremely valuable source of reference and many stimulating ideas...the main repository of information in a rapidly devloping subject"--The Lancet"Provides unrivalled value in both academic and fiscal terms and should be purchased by hard pressed librarians as a major priority to be jealously defended."--Journal of Medical Microbiology"A very valuable serial publication...no serious student of immunology can afford to be without it."--Archives of Biochemistry and Biophysics

  • Advances in Immunology

    • 1st Edition
    • Volume 60
    • English
    This volume highlights the latest reviews of mechanisms and actions of the immune system and the host response to infection and inflammation.

  • Immunoglobulin Genes

    • 2nd Edition
    • Tasuku Honjo + 1 more
    • English
    The immunoglobulin gene complex is responsible for generating an extraordinarily wide range of antibodies, each possessing a unique antigen specificity. The Second Edition of Immunoglobulin Genes brings the reader up to date with the rapid progress in our understanding of this system. Firmly established as the definitive book on the topic, it provides a fully comprehensive account of the organization, function, rearrangement and expression of these and related genes. Since the publication of the first edition, the work has been extensively revised and updated to cover new research data on human immunoglobulin genes as well as mammalian and lower vertebrate systems. New chapters include "Somatic mutation and B cell Maturation", "Antigen receptors" and "B lymphocyte tolerance in the mouse."For the immunologist, there are detailed descriptions of the molecular mechanisms which generate this diverse range of antibodies and the tight regulation of the genes encoding them. Molecular biologists will find discussions of important phenomena including gene rearrangement, differential splicing and deletion in the context of immunoglobulin genes.The excitement of research on immunoglobulin genes is conveyed by the range and complexity of issues discussed here; the book contains invaluable information for clinicians and research scientists with an interest in the immune response.

  • Advances in Immunology

    • 1st Edition
    • Volume 59
    • English
    With contributions from Steven A. Porcelli and other internationally recognized leaders in the field, this volume continues the tradition of indispensable reviews. Papers on the CD1 family, positive selection of thymocytes, and molecular and cellular aspects of XLA highlight the latest volume.

  • Immunology: The Making of a Modern Science

    The Making of a Modern Science
    • 1st Edition
    • Richard B. Gallagher + 3 more
    • English
    Immunology has progressed in spectacular fashion in the last four decades. Studies of the response to infectious agents, transplanted organs and tumours (and the potential to manipulate that response), and the study of the immune system as a model system in molecular cell biology have yielded dramatic advances in our understanding of the mechanisms of immunity.The field has attracted a continuous stream of the brightest theoretical and experimental scientists for over forty years. This book conveys the philosophies and approaches of sixteen of the most successful of these scientists in the form of a series of narratives that describe the circumstances that led to a major discovery in immunology. Contributors not only recall an exciting period of research that helped shape modern immunology, but set it in the personal context of place and time. Jacques Miller, for example, describes the discovery of the function of the thymus, Rolf Zinkernagel explains how experiments on viral immunity led to the discovery of MHC restriction and Susumu Tonegawa provides an account of how antibody gene structure was defined. Medically-important discoveries include descriptions of early studies of autoimmunity by Noel Rose and of tumour immunology by George and Eva Klein.Far from being a collection of disinterested, historical accounts, this volume comprises a series of passionately biographical, personal essays that provide an unusually intimate insight into the scientific process. This book will be essential, and fascinating, reading for all those with an interest in immunology, and in the life sciences in general. For students and teachers, this will provide the background necessary for a true understanding of immunology, and to place subsequent discoveries in perspective.

  • Immunopharmacology of Platelets

    • 1st Edition
    • M. Joseph
    • English
    Platelets have long been the subject of much investigation in the areas of vascular physiology, biochemistry, immunology and physiopathology. Their ability to react to environmental stimuli, to modify their shape and metabolism despite being anuclear, has fascinated scientists.This volume looks specifically at the involvement of blood platelets outside their 'classical' field of application, in the physiopathological mechanics of allergy and inflammation. The coverage includes the role of platelets in bacterial, parasitic and viral diseases and in tumour cell interactions.

  • Glycoproteins I

    • 1st Edition
    • Volume 29
    • J. Montreuil + 2 more
    • English
    Part I covers modern advances in the determination ofglycoprotein structure and in the biosynthesis of mammalian,bacterial, yeast, plant and insect glycoproteins. There are alsotwo chapters on functional aspects (glycoprotein hormones andcollagens).The content of the volume is very comprehensive in that, mostcontributors have focussed on discussing, in depth, the wealthof most recent advances in their field, and referring to previousreviews of older work for background information. This method caneffectively produce a very wide subject coverage in a smallernumber of chapters/volumes.The volume is an importantinformation source for all glycobiologist researchers (seniorinvestigators... post-doctoral fellows and graduate students), andas a good, comprehensive, reference text for scientists working inthe life sciences.

  • Dictionary of Immunology 4E

    • 4th Edition
    • W. John Herbert + 2 more
    • English
    This is the fourth edition of a well-established dictionary of Immunology which has been completely revised and updatedto include key terms arising from new discoveries in the fast-developing fields of molecular and cellular immunology. It also contains brief descriptions of the most commonly used immunological techniques, as well as definitions, useful in clinical immunology, of immunodeficiency states, autoimmune diseases etc. Clear illustrations and tables have been added to illustrate the text where appropriate. The book should be readily understandable by anyone with a background in biology and many of the definitions should be understandable to the general reader, especially as terms are extensively cross-referenced.It should be useful to those attending immunological meeting or reading immunological journals, especially as scientists communicating to specialized audiences rarely define their terms.It will also be invaluable to undergraduate and postgraduate students in biological and medical sciences, since immunological methods, such as use of monoclonal antibodies, are in wide use throughout biology and medicine.

  • Immunopharmacology of Free Radical Species

    • 1st Edition
    • English
    Free radicals have been implicated in a entire host of different human disease states, which suggests that although they may not have a pivotal causal role, they are involved in the perpetuation of disease. In recentyears, it has become evident that although free radicals most certainly do have this role in perpetuating inflammatory reactions, they have perhaps a far more important role in acting as second messenger systems to maintain normal cell function. It is theperturbations of these reactions which pose the most intriguing therapeutic challenges. This volume deals with various basic mechanisms of free radical processes and injury. The emphasis in each case is on potential therapeutic strategies developing fromthis new knowledge.

  • Mechanisms and Models in Rheumatoid Arthritis

    • 1st Edition
    • B. Henderson + 2 more
    • English
    Rheumatoid arthritis is a bewilderingly complex disease involving the interactions of many, and varied, cell populations and multiple families of low and high molecular mass mediators. We are only slowly beginning to understand the mechanisms that produce the local and systematic pathology clinically recognized as rheumatoid arthritis. Increasingly, use is being made of experimental models of this disease in an effort to test hypotheses about putative pathological mechanisms and to investigate the effect of novel therapeutic agents. A major section of this book covers these experimental models in great detail from their development through to reviews of the most recent information on each model.Mechanisms and Models in Rheumatoid Arthritis brings together a group of eminent researchers from the fields of clinical rheumatology, pathology, experimental pathology, immunology, connective tissue biochemistry, microbiology, pharmacology and developmental biology to describe the current views of the cellular and humoral mechanisms that drive the pathology of rheumatoid arthritis and experimental models of rheumatoid arthritis.

  • Advances in Immunology

    • 1st Edition
    • Volume 58
    • English
    This text should be a useful guide for researchers in immunology, cell and molecular biology and development biology.

  • Advances in Immunology

    • 1st Edition
    • Volume 57
    • English

  • Autoimmune Disease Models

    • 1st Edition
    • Irun R. Cohen + 1 more
    • English
    Because autoimmune disorders can wreak havoc in both humans and animals, these disorders are now the objects of intense and focused research. This book details specific animal models for a variety of autoimmune disorders. The contributors are recognized authorities who deal with the panoply of experimentally induced autoimmune disorders, including encephalomyelitis, allergic neuritis, uveoretinitis, myocarditis, and hepatitis. Also included are discussions of spontaneously appearing diseases such as autoimmune thyroiditis and systemic lupus erythematosus. Many other disorders are also covered in this comprehensive guide. Certain to be an aid in the planning of individual experiments and broader research programs, this book will be a valuable addition to the library of all practicing immunologists interested in immune system function and dysfunction.

  • Adhesion Molecules

    • 1st Edition
    • English
    The consequences of diseases involving the immune system such as AIDS, and chronic inflammatory diseases such as bronchial-asthma, rheumatoid arthritis and atherosclerosis, now account for a considerable economic burden to governments worldwide. In response there has been an enormous research effort investigating the basic mechanisms underlying such diseases, and a tremendous drive to identify novel therapeutic applications for their prevention and treatment. Though a plethora of immunological studies have been published in recent years, little has been written about the implications of such research for drugs development. As a consequence, this area has not gained the prominence of other fields such as molecular pharmacology or neuropharmacology, and a focul information source for the many pharmacologists interested in diseases of the immune system remains unpublished.The Handbook of Immunopharmacology series provides such a source through the commissioning of a comprehensive collection of volumes on all aspects of immunopharmacology. Editors have been sought after for each volume who are not only active in their respective areas of expertise, but who also have a distinctly pharmacological bias to their research.The series follows three main themes, each represented by volumes on individual component topics. The first covers each of the major cell types and classes of inflammatory mediators ("cells and mediators"). The second covers each of the major organ systems and the diseases involving the immune and inflammatory responses that can effect them ("systems"). The third covers different classes of drugs currently used to treat these diseases as well as those under development ("drugs").This volume provides a comprehensive overview of the adhsion molecules, processes and concepts that govern both inflammatory and infectious diseases, and also deals in detail with the specific in vivo pathways involved.The first chapter introduces some of the molecules that mediate leukocyte adhesion and ranges from their discovery using monoclonal antibodies and a congenital adhesion deficiency, to their antagonism in preliminary clinical trials as novel therapeutics. An in-depth analysis of the structure, distribution and function of the cell surface glycoproteins that regulates lymphocyte (specific immune response), granulocyte (acute inflammatory response) and metastatic cell (malignant processes) adhesions respectively is provided by the next three chapters. Chapters 5 and 7 detail the molecular structure, intracellular pathways, specificty of carbohydrate interactions, and signalling of the molecules that regulate leukocyte-leukocyte and leukocyte-mesenchyma... cell interactions.There follows an exploration into the contributions of specific molecules in inflammatory diseases in various organs from chapters 8-11. The concluding part is unique to this volume by reviewing the comparable, and in some cases same, cell surface molecules that mediate virus, bacteria and parasite interactions with host cells.The research is far from complete, but Adhesion Molecules is extremely comprehensive and will be a valuable resource for many a year to come.

  • Cytokine-Induced Tumor Immunogenicity

    From Exogenous Molecules to Gene Therapy
    • 1st Edition
    • Guido Forni + 3 more
    • English
    This remarkable book focuses on the field of cytokines and tumor immunogenicity, in which there has been a recent resurgence of interest, especially with the advent of gene therapy. With major sections devoted to concepts, experimental models, and clinical perspectives, this volume includes chapters from nearly every research group actively contributing to this area. The excitement that pervades the field is captured, and the prospects for the future discussed. The information presented here will provide essential reading for a wide spectrum of basic as well as clinical investigators interested in cytokines and the prospects for successful cancer therapy.

  • Advances in Cancer Research

    • 1st Edition
    • Volume 63
    • English
    This latest volume of the biannual serial continues rapid, current coverage of all aspect of the molecular basis of human cancer, functions of oncogenes , and research strategies of cancer drug development and treatment

  • Immunopharmacology of Macrophages and Other Antigen-Presenting Cells

    • 1st Edition
    • English
    The consequences for diseases involving the immune system such as AIDS, and chronic inflammatory diseases such as bronchial asthma, rheumatoid arthritis, and atherosclerosis, now account for a considerable economic burden to governments worldwide. In response there has been an enormous research effort investigating the basic mechanisms underlying such diseases, and a tremendous drive to identify novel therapeutic applications for their prevention and treatment. Though a plethora of immunological studies have been published in recent years, little has been written about the implications of such research for drug development. As a consequence, this area has not gained the prominence of other new fields such as molecular pharmacology or neuropharmacology, and a focal information source for the many pharmacologists interested in diseases of the immune system remains unpublished.The Handbook of Immunopharmacology Series provides such a source through the commissioning of a comprehensive collection of volumes on all aspects of immunopharmacology. Editors have been sought after for each volume who are not only active in their respective areas of expertise, but who also have a distinctly pharmacological bias to their research.The Series follows three main themes, each represented by volumes on individual component topics. The first covers each of the major cell types and classes of inflammatory mediators ("cells and mediators"). The second covers each of the major organ systems and the diseases involving the immune and inflammatory responses that can affect them ("systems"). The third covers different classes of drugs currently used to treat these diseases as well as those under development ("drugs").

  • Immunopharmacology of Epithelial Barriers

    • 1st Edition
    • English
    The realisation that epithelial tissues are not simply passive barriers to the adsorption of materials into internal environments has brought about an enormous growth of investigation of mucosal functions and their active and passive protective roles. Epithelia are highly organized but complex structures, subserving numerous functions, including immunological defence. The use of pharmacological tools in these systems is increasing, which is improving our understanding of epithelial immunobiology. This volume adopts a step-by-step approach, whereby each chapter builds upon the previous one, progressively adding important foundation information, culminating in a series of chapters concerning particular epithelia, including respiratory, gastrointestinal, renal and ocular. The result is a comprehensive but integrated treatise of epithelial function and its immunopharmacology, which aims to serve as an appropriate starting point at which the clinical pulmonologist and the research scientist can obtain an appreciation of some aspects of epithelial immunopharmacology as they are currently understood.

  • Advances in Immunology

    • 1st Edition
    • Volume 55
    • English
    Approx.455 pages

Related subjects