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Books in Cellular immunology

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    • Mitochondrial Signaling and Regulation

      Immune Responses and Diseases
      • 1st Edition
      • Seyyed Shamsadin Athari + 1 more
      • English
      Mitochondrial Signaling and Regulation: Immune Responses and Diseases delves into the latest research on molecular pathophysiology mechanisms and cell signaling pathways in the pathogenesis of diseases via mitochondrial regulation. This comprehensive study underscores the importance of mitochondria in cellular processes and their role in disease development. Early chapters discuss the crucial role, regulation, and crosstalk of mitochondria, highlighting their significance in maintaining cellular health. The exploration of mitochondria mutations and mitochondria-related diseases follows, providing a detailed understanding of the genetic aspects involved.Final chapters focus on mitochondria's involvement in immune responses and allegro-inflammation... presenting the intricate connections between mitochondrial function and the immune system. The book also explores the use of biotechnology in developing new treatments and targeted therapies against mitochondrial dysfunction. This resource sets the foundation for new classifications, prevention methods, therapies, and treatments of mitochondria-related diseases, making it invaluable for scientists and researchers dedicated to this field.

    • Immunology of Recurrent Pregnancy Loss and Implantation Failure

      • 1st Edition
      • Joanna Kwak-Kim
      • English
      Immunology of Recurrent Pregnancy Loss provides doctors and immunologists with the information they need to help couples who experience recurrent pregnancy losses. Sections cover unexplained infertility, repeated in vitro fertilization, embryo transfer failures, history of second or third trimester pregnancy losses of unknown cause, or pregnancy with a history of or active autoimmune and/or alloimmune disease. Reproductive failure (RF), including recurrent pregnancy losses (RPL) and repeated implantation failures (RIF) is rather a syndrome than a disease caused by multiple etiologies, such as anatomical, endocrine, genetic, infectious, immunological, thrombotic and unexplained etiologies, hence this book strives to present the latest information. In 27 chapters, divided in 5 sections, the book introduces the current update of reproductive immunology topics in RF and provides systematic diagnostic guidelines, systemic and immune etiologies and therapeutic approaches.

    • Translational Inflammation

      • 1st Edition
      • English
      Translational Inflammation links laboratory and clinical data within primary and secondary care to clinical research data and offers a holistic and innovative approach to chronic inflammation and ageing. Understanding the role of inflammation as a part of clinical disease states is becoming a valuable tool in both direct treatment and the development of therapeutics. Translational Inflammation, the 4th volume in the Perspectives in Translational Cell Biology series, offers content for professors, students and researchers across basic and translational biology.

    • Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging

      Volume 12
      • 1st Edition
      • M. A. Hayat
      • English
      Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging, Volume 12 discusses and details almost all aspects of the autophagy machinery in the context of health, cancer and other pathologies. Autophagy is more widely accepted as beneficial given its role in eliminating ‘toxic assets’ and promoting cell viability, hence, it has emerged as a new and potent modulator of disease progression that is both scientifically intriguing and clinically relevant. As the latest release in the Autophagy book series, users will find a detailed explanation of the role of molecular mechanisms.

    • Molecular Characterization of Autophagic Responses Part A

      • 1st Edition
      • Volume 587
      • English
      Molecular Characterization of Autophagic Responses, Part A, presents a collection of methods for the qualitative and quantitative evaluation of virtually all the morphological, biochemical, and functional manifestations of autophagy, in vitro, ex vivo and in vivo, in organisms as distant as yeast and man. Autophagy is an evolutionarily conserved mechanism for the lysosomal degradation of superfluous or dangerous cytoplasmic entities, and plays a critical role in the preservation of cellular and organismal homeostasis. Monitoring the biochemical processes that accompany autophagy is fundamental for understanding whether autophagic responses are efficient or dysfunctional.

    • Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging

      Volume 10
      • 1st Edition
      • M. A. Hayat
      • English
      Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging, Volume 10 offer a valuable guide to both cellular processes, while encouraging researchers to explore their potentially important connections. Autophagy serves to maintain healthy cells, tissues, and organs, but also promotes cancer survival and growth of established tumors. Impaired or deregulated autophagy can also contribute to disease pathogenesis. This is the tenth volume of the multivolume series that discusses, in detail, almost all aspects of the autophagy machinery in the context of health, cancer, and other pathologies. Autophagy maintains homeostasis during starvation or stress conditions by balancing the synthesis of cellular components and their deregulation by autophagy. Volume 10 of the Autophagy series discusses the role of a novel binuclear palladacycle complex that inhibits melanoma growth through apoptosis and autophagy.

    • Osteoimmunology

      Interactions of the Immune and Skeletal Systems
      • 2nd Edition
      • Joseph Lorenzo + 4 more
      • English
      Osteoimmunology: Interactions of the Immune and Skeletal Systems, Second Edition, explores the advancements that have been made in the field during the last 40 years, including valuable information on our understanding of the interactions between hematopoietic, immune, and bone cells, now known as the field of osteoimmunology. This comprehensive work offers the most extensive summaries of research trends in the field and their translation into new therapeutics. Early chapters deal with the development of osteoblasts, osteoclasts, hematopoietic stem cells, T and B-lymphocytes, and communications between these cellular elements, while later sections contain discussions of the signaling pathways by which RANKL influences osteoclast development and function. Subsequent chapters explore the effects that estrogen has on bone and the immune system, the development of pathologic conditions, and the growing research around osteoporosis, Paget’s disease, the genetics of bone disease, and bone cancer metastasis.

    • Personalized Immunosuppression in Transplantation

      Role of Biomarker Monitoring and Therapeutic Drug Monitoring
      • 1st Edition
      • Michael Oellerich + 1 more
      • English
      Personalized Immunosuppression in Transplantation: Role of Biomarker Monitoring and Therapeutic Drug Monitoring provides coverage of the various approaches to monitoring immunosuppressants in transplant patients, including the most recently developed biomarker monitoring methods, pharmacogenomics approaches, and traditional therapeutic drug monitoring. The book is written for pathologists, toxicologists, and transplant surgeons who are involved in the management of transplant patients, offering them in-depth coverage of the management of immunosuppressant therapy in transplant patients with the goal of maximum benefit from drug therapy and minimal risk of drug toxicity. This book also provides practical guidelines for managing immunosuppressant therapy, including the therapeutic ranges of various immunosuppressants, the pitfalls of methodologies used for determination of these immunosuppressants in whole blood or plasma, appropriate pharmacogenomics testing for organ transplant recipients, and when biomarker monitoring could be helpful.

    • Immunological Tolerance

      Mechanisms and Potential Therapeutic Applications
      • 1st Edition
      • David H. Katz + 1 more
      • English
      Immunological Tolerance: Mechanisms and Potential Therapeutic Applications documents the proceedings of a conference held at Brook Lodge, Michigan, April 27-May 1, 1974. The conference brought together many of the investigators who have actively contributed to furthering knowledge and understanding of immunological tolerance. It will be immediately clear to the reader that the conference was structured in a way to consider phenomena of tolerance and immune suppression as interrelated entities with a certain degree of emphasis on the possible common cellular mechanisms involved. The volume contains 36 contributions presented during the seven sessions of the conference. The papers presented in Session I examined T-cell tolerance. The presentations in Session II focused on B cell tolerance. The papers in Sessions III and IV focused on the mechanisms of B cell and T cell tolerance, respectively. Session V dealt with the activity of suppressor cells as a mechanism of tolerance. The papers in Session VI investigated the suppressive activity of antibody and antigen-antibody complexes. In Session VII a final General Discussion was held in order to identify what has been established concerning the phenomenology and mechanisms of specific immunological tolerance, what are the major unresolved issues, and what approaches appear most promising to answer these questions.

    • Calcium Disorders

      Butterworths International Medical Reviews: Clinical Endocrinology
      • 1st Edition
      • David Heath + 1 more
      • English
      Clinical Endocrinology 2: Calcium Disorders presents an extensive examination of the treatment of postmenopausal and senile osteoporosis. It discusses the acquired disorders of vitamin D metabolism. It addresses the prevention of osteoporosis. Some of the topics covered in the book are the classification of rickets; mechanisms of homeostasis; transepithelial transport of phosphate anion; definition of mendelian rickets; treatment of; classification of androgens and synthetic anabolic agents; and assessment of parathyroid function. The measurement of parathyroid hormone is fully covered. An in-depth account of the indirect assessment of parathyroid activity is provided. The acquired disorders of Vitamin D metabolism are completely presented. A chapter is devoted to the aetiological views of rickets and osteomalacia. Another section focuses on the treatment and prevention of rickets and osteomalacia. The analysis of renal osteodystrophy, hypercalcemia, and familial hypocalciuric hypercalcemia are briefly covered. The book can provide useful information to doctors, endocrinologists, students, and researchers.