Drug discovery print books and ebooks | Elsevier

Antimicrobial Therapeutics and Drug Discovery

1st Edition
March 1, 2026
Chengyuan Liang + 1 more
English

Antimicrobial Therapeutics and Drug Discovery is a comprehensive resource that provides an overview of antimicrobial drug discovery. It covers a wide spectrum of pathogenic organisms causing human infections, exploring alternative therapeutic strategies beyond traditional small molecule drugs. The contents in the book are structured into four parts, each focusing on a different aspect of antimicrobial drug discovery. From exploring viral and host targets, understanding antibiotic resistance mechanisms, to the potential of nanomedicine and computational approaches, the book offers a comprehensive view of the field. Employing a multidisciplinary approach, chapters discuss the importance of drug discovery for fungi, Mycobacteria, Mycoplasma, and parasites, and offers insights into innovative biomedical approaches and combination therapies. By bridging the gap between experimental research and practical application, Antimicrobial Therapeutics and Drug Discovery is a key reference for pharmacologists and pharmaceutical scientists working in academic and corporate research. Medicinal chemists and microbiologists will also benefit from the multidisciplinary coverage of the book.

Chalcones

1st Edition
March 1, 2026
Simone Carradori + 2 more
English

Chalcones: From Drug Discovery to Pharmaceutical Applications serves as a comprehensive reference on chalcones, detailing their natural occurrence, synthetic methods, and therapeutic applications. Chalcones are characterized by their accessible preparation and chemical versatility, making them a focal point for research in drug development. This text aims to provide both novice and experienced researchers with the foundational knowledge necessary to advance their work in this area. The book is organized into three parts. Part I, “Foundations of Chalcones Research,” covers the natural sources of chalcones, various extraction methods, structural characterization techniques, synthesis, and their role in organic chemistry and metal complexes. Part II, “Pharmacology of Chalcones,” addresses pharmacokinetic properties, toxicity, and the medicinal uses of chalcones, including their effectiveness against viruses, bacteria, cancer, and neurodegenerative diseases. Part III, “Prospects,” explores chalcone-containing products, drug formulation strategies, and clinical trials involving chalcone-based drug candidates. This reference is an essential resource for pharmaceutical researchers, providing critical insights into the applications and potential of chalcones in drug development and therapeutic interventions.

The Renaissance in GPCR Research and Drug Discovery

1st Edition
February 1, 2026
Terry P. Kenakin
English
Paperback
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eBook
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The Renaissance in GPCR Research and Drug Discovery: Receptor Function, Receptor Structure, New Techniques, Characterization of Drug Activity, Drug Discovery is a comprehensive reference for pharmacology researchers. It focuses on utilizing novel aspects of GPCR function for therapeutic advantage and applying new chemical types to modify GPCR behavior. Recent advancements have revitalized GPCR discovery, opening unexplored avenues for new drug development. The book's content is meticulously divided into five distinct parts, covering evolutionary perspectives, novel functions, investigative technologies, therapeutic modalities, and a broad range of GPCR ligands.Beyond these key topics, the book delves into the evolution of GPCRs as drug targets, the mechanisms behind their novel functions, and the latest technologies driving research and discovery. It also highlights new and recently approved therapeutic modalities and provides a broad coverage of GPCR ligands. Edited and authored by leading researchers, this book serves as an essential reference for drug discovery researchers and medicinal chemists, as well as AI researchers exploring this drug discovery space.

Natural Product Drug Discovery

1st Edition
February 1, 2026
Ning Li + 1 more
English

Natural Product Drug Discovery: Highly Anticipated Natural Molecules provides a comprehensive examination of the role of natural products in innovative drug development. This research level reference addresses the significant challenges that highly active natural molecules face in the drug development process, including issues related to bioavailability and potency. The book presents detailed analyses of various classes of natural products, including polysaccharides, volatile oils, and diterpenoids, exploring their chemical properties, biological activities, and potential clinical applications. Each chapter is authored by leading experts in the field, offering insights into structural modification techniques, naturally sourced inhibitors, and the application of green biomanufacturing strategies to enhance drug development. This volume in the Drug Discovery Opinion series serves as an essential resource for researchers, pharmacologists, and industry professionals involved in natural product drug discovery. It provides the necessary information to navigate the complexities of this field, emphasizing the integration of traditional knowledge with modern scientific approaches. Through a thorough understanding of these natural compounds, this book aims to contribute to the advancement of therapeutic innovations in pharmacotherapy.

Medicinal Plants

2nd Edition
February 1, 2026
Da-Cheng Hao + 1 more
English

Medicinal Plants: Chemistry, Biology, and Omics, Second Edition is a reference to help researchers identify and master the patterns in the distribution of medicinal compounds on the phylogenetic tree to explore new drug resources and develop novel therapies against different diseases. The book provides a deeper understanding of how the interrelationship between phytometabolites, bioactivities and omics techniques facilitates sustainable conservation and application of phytomedicine resources. Now in 2nd edition, the contents have been updated to include topics as machine learning applications, geographic distribution of phytometabolites, comparative analysis of alkaloids, expanded coverage of selected taxa, and conditions like cardiovascular disease and cancer. The book is structured around chemotaxonomy. After an introduction and review of taxonomy, chemistry, biology and omics, the authors dive into a taxon-guided exploration of medicinal resources for Fritillaria, Chelidoniae, Dichocarpum, Aconitum, Cimicifugeae, Clematis, Potentilla, Rubus, Cannabis, and other taxa. All chapters follow a similar and consistent structure, offering detailed information on each of them. Researchers in phytopharmacology can acquire in-depth understanding of the interrelationships between chemistry, biology and omics, as well as the implications of the link between phylogeny, phytometabolites and bioactivities in medical biotechnology and sustainability. Clinicians can better understand the principles of mutual interactions between phytometabolites and drug efficacy.

Emerging Trends in Phytotherapy of Cancer

1st Edition
December 1, 2025
Mahendra Rai + 1 more
English
Paperback
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eBook
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Emerging Trends in Phytotherapy of Cancer is an essential reference that explores the multifaceted role of medicinal plants in combating cancer. The book covers a broad range of interconnected topics including ethnomedicinal plants used in cancer by tribes and aboriginals, herbs used in Ayurvedic medicine for cancer, integrated approaches of modern and conventional drugs, anti-cancerous secondary metabolites, plant-based anticancer drugs approved by FDA and WHO, toxicity to humans, and the role of emerging technologies such as the applications of nanotechnology and artificial intelligence. The contents are divided into six parts. Part one opens with an introductory chapter, followed by the different combinations of plant-based drugs and modern medicine for cancer treatment, and recent developments in cancer research. Part two discusses the ethnomedicinal uses of plants in cancer and the role of Ayurvedic herbal medicines in cancer. Part three incorporates the role of secondary metabolites in cancer treatment. Part four elaborates on the plant-based drugs recommended by FDA/WHO. Part five concerns the human phytotoxicity of secondary metabolites, and part six describes the role of emerging nanotechnologies and artificial intelligence in phytotherapy drug delivery and treatment. Targeted at researchers, healthcare professionals, and advanced students in related fields, this book provides technical and in-depth knowledge, contributing to ongoing advancements in cancer treatment. It uniquely integrates ethnomedicinal therapies with modern technologies, offering a comprehensive overview of the research into phytomedicinal cancer therapies.

Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders

2nd Edition
November 1, 2025
Adeboye Adejare
English
Hardback
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eBook
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Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders: Alzheimer’s Disease, Second Edition delves into the complexities of drug discovery, specifically for Alzheimer's Disease, presenting the necessary paradigm for future success in research and treatment. This edition is thoroughly updated with recent developments in therapeutic strategies, including amyloid hypothesis, tau, apo E, insulin, and others, and introduces a new chapter on drug delivery to the brain. Additionally, the book encompasses diagnosis, epidemiology, drug discovery strategies, current therapeutics, and more, offering a comprehensive approach to Alzheimer's Disease.It covers the latest in targeted drug design, preclinical studies, and animal models, making it an essential resource for pharmaceutical scientists, pharmacologists, neuroscientists, and clinical researchers. Patients and advocacy groups can also gain valuable insights from the overview of current treatments and scientific advancements in the field.

Deep Learning in Drug Design

1st Edition
October 1, 2025
Qifeng Bai + 2 more
English
Paperback
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eBook
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Deep Learning in Drug Design: Methods and Applications summarizes the most recent methods, and technological advances of deep learning for drug design, which mainly consists of molecular representations, the architectures of deep learning, geometric deep learning, large models, etc., as well as deep learning applications in various aspects of drug design. This book offers a comprehensive academic overview of deep learning in drug design. It begins with molecular representations, CNNs, GNNs, Transformers, generative models, explainable AI, large models, etc. Next, it covers deep learning applications like protein structure prediction, molecular interactions, ADMET prediction, antibody design, and so on. Finally, a separate chapter is dedicated to the introduction of the ethics and regulation of artificial intelligence in drug design. This book is ideal for readers aiming to learn and implement deep learning methods and applications in drug design and related fields.Deep Learning in Drug Design: Methods and Applications is particularly helpful to undergraduate, graduate, and doctoral students in need of a practical guide to the principles of the discipline. Established researchers in the area will benefit from the detailed case studies and algorithms presented.

Intelligent Nanobiosystems in Medicine and Healthcare, Volume 1

1st Edition
March 28, 2025
Vijay Mishra + 2 more
English
Paperback
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eBook
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Intelligent Nanobiosystems in Medicine and Healthcare, Volume One: Fundamentals, Fabrication and Commercialization provides an overview of recent progress in the nanobiosystems arena, helping readers design and develop novel drug delivery systems and devices that take advantage of recent advances in nanomedical technologies. The book explores a wide range of promising approaches for the diagnosis and treatment of diseases using the latest advancement in cutting-edge nanomedical technologies. It highlights established research and technology on intelligent nanobiosystems, their rapidly emerging aspects, and future research directions. Sections cover nanobiosystems, explore nano candidates and fabrication aspects, and delve into the challenges of commercialization.Th... book will be a useful resource for researchers and postgraduate students in pharmaceutical sciences and biotechnology as well as medical professionals, biologists, chemists, materials scientists, clinical researchers, biochemical and biomedical engineers working both in academia and industry.

Medicinal Chemistry and Drug Development

1st Edition
February 5, 2025
Gang Liu
English
Paperback
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eBook
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Medicinal Chemistry and Drug Development describes the key events and roles of medicinal chemistry in the discovery and development of lead compounds into drugs, including target identification, which is accomplished by using 30 case studies. This book outlines all the stages of drug development, including the discovery of active compounds, research on the pharmacologicalprope... of molecules, and confirmation of drug targets. The role of the case studies is to show the common factors in the successful development of drugs, thereby showing medicinal chemists how best to explore the scientific pathways when developing new drugs. This makes the book especially relevant for senior university students majoring in pharmaceutical sciences as well as graduate students and researchers.

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