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Elsevier

Elsevier Science

  • Basic Gas Chromatography-Mass Spectrometry

    Principles and Techniques
    • 1st Edition
    • F.W. Karasek + 1 more
    • English
    The book begins by covering the basic principles of both gas chromatography (GC) and mass spectrometry (MS) to the extent necessary to understand and deal with the data generated in a GC-MS analysis. The focus then turns to the particular requirements created by a direct combination of these two techniques into a single instrumentation system. The data generated and their use are covered in detail. The role of the computer and its specific software receives special attention, especially in the matter of compound identification via mass spectral search techniques. GC-MS-computer instrumentation has reached such a plateau of excellence today that the present commercial systems will not be obsolete for a long time to come. Therefore, a detailed description of these systems is not only informative but is also pertinent to the subject matter of this book. Finally, representative applications and results obtained with GC-MS-computer techniques are presented and chosen in such a way as to permit extrapolation of specific applications to similar problems encountered by the reader. To aid the reader in mastering the subject matter and increase understanding, interpretation problems and suggested readings are included. The format is instructional, informative and application-oriented with material presented in such a way as to be useful to a broad spectrum of people.The book serves as a text in its own right.The software package Gas Chromatography-Mass Spectrometry: A Knowledge Base, by F.A. Settle, Jr. and M.A. Pleva provides rapid access to a wealth of current information in the GC-MS field. Its three diskettes (51/4 inch) allow the user three ways to access: the index mode, the tree mode and a keyword search mode. The package may be purchased separately and is available for the IBM-PC and compatibles.The software provides a valuable supplement to the book.

  • Chemistry of Soil Organic Matter

    • 1st Edition
    • Volume 17
    • K. Kumada
    • English
    Despite the large number of papers and books published on soil organic matter (humus), our knowledge of the subject is still very limited, as is our knowledge of humic acid. The author of this book began to study humus at the end of the 1940s and continued until 1984 when he retired from Nagoya University. With the intention of establishing a systematic understanding of soil organic matter, he has compiled facts and a discussion of humus based on his extensive experimental results during the past 40 years.In this book, humic acids are classified into A, B, Rp and P types, based on their optical properties. The elementary composition and other chemical properties of humic acid types are shown to be regularly different from each other. A new method for humus composition analysis applied to various kinds of soils in Japan and several other countries indicates that the diversity of humus compositions of soils is systematically understandable. These findings lead the author to novel theories on the chemical configuration and formation of humic acids and humic substances. Diagenesis of humus under terrestrial conditions is illustrated as to the buried humic horizons of Black soil (Andosol).The book will be useful not only to soil scientists and agronomists but also to geochemists, oceanographers, limnologists, water scientists, biologists and chemists who are dealing with organic matter in terrestrial, aquatic, and sedimentary environments.

  • Teratogens

    Chemicals Which Cause Birth Defects
    • 1st Edition
    • Volume 31
    • V. Kolb Meyers
    • English
    This multi-author work deals with the practical aspects of teratogens - chemicals which cause birth defects. It is designed for use as a unique guide to these chemicals in which one can find all relevant information. The issues covered include: how to obtain information about the teratogenic potential of chemicals; teratogenic chemicals in undergraduate chemistry laboratories; safe handling of teratogenic chemicals; teratogenicity of pesticides and other pollutants in the environment; occupational exposure and pregnancy outcome; identification and prevention of reproductive hazards in industry; and the long-term effects of chemicals on the developing brain. A list of approximately 5,000 chemicals known to cause reproductive effects is given. A comprehensive bibliography is included with each chapter providing up-to-date references for more in-depth coverage. The monograph will be of interest to academic and industrial chemists, health professionals, as well as both undergraduate and graduate students in health and related sciences.

  • Progress in Medicinal Chemistry

    • 1st Edition
    • Volume 25
    • English
    There are five main subject areas in this volume in the series on medicinal chemistry. The first is a review of the understanding of Alzheimer's disease and the development of drugs for its treatment; the second, looking at recent efforts in modifying a naturally occuring anticancer (campothecin) for chemotherapy; the third covers the problem of getting a drug to a specific site within the context of phosphates and phosphonates; a survey of sterilization using aldehydes for the destruction of microbes both inside and outside the human body is reviewed in the fourth; and the last chapter is an account of the progress made in the biologically active enantiomer for complex synthetic asymmetric drug molecules.

  • Electrode Kinetics: Reactions

    • 1st Edition
    • Volume 27
    • R.G. Compton
    • English
    Volumes 26 and 27 are both concerned with reactions occurring at electrodes arising through the passage of current. They provide an introduction to the study of electrode kinetics. The basic ideas and experimental methodology are presented in Volume 26, whilst Volume 27 deals with reactions at particular types of electrodes.Chapter 1 of the present volume deals with redox reactions at metal electrodes, Chapter 2 with semiconducting electrodes and Chapter 3 with reactions at metal oxide electrodes. Both theoretical aspects and experimental results are covered.

  • Molecular Genetics of Immunoglobulin

    • 1st Edition
    • Volume 17
    • F. Calabi + 1 more
    • English
    Our understanding of the molecular genetics of immunoglobulins has been enormously advanced by the application of recombinant DNA technology. This new volume in the popular series New Comprehensive Biochemistry contains eight chapters that draw together reviews summarising the research into immunoglobulins and the arrangement, rearrangement and expression of their gene structure.Molecular Genetics of Immunoglobulin will be of particular importance to those working in the areas of genetics and molecular biology, immunology, and cell biology.

  • Selective Sample Handling and Detection in High-Performance Liquid Chromatography

    • 1st Edition
    • Volume A
    • English
    This book is the first of a two-volume project which attempts to treat the sample handling and detection processes in a liquid chromatographic system in an integrated fashion. The need for more selective and sensitive chromatographic methods to help solve the numerous trace analysis problems in complex samples is undisputed. However, few workers realize the strong interdependence of the various steps - sample handling, separation and detection - which must be considered if one wants to arrive at an optimal solution. By introducing a strong element of selectivity and trace enrichment in the sample preparation step, fewer demands are placed on the quality of the chromatography and often a simple UV detector can be used. By using a selective detection mode, i.e. a reaction detector, the sample handling step can frequently be simplified and more easily automated. The impact of such a ``total system'' approach on handling series of highly complex samples such as environmental specimens or biological fluids can be easily imagined.Each chapter includes sufficient references to the literature to serve as a valuable starting point for more detailed investigation. Special emphasis is placed on the sample handling, and high priority has been given to the treatment of chemical principles applied to the topics presented, rather than to instrumentation. Written by experienced practitioners, this volume will be of interest to investigators in many areas of application, including environmental scientists and those active in the clinical, pharmaceutical and bioanalytical fields.

  • Carbonate-Clastic Transitions

    • 1st Edition
    • Volume 42
    • Laurence (Hy) Doyle + 1 more
    • English
    Over the years, the field of sedimentology has become subdivided into various specialities. Two of the largest groups are those who study clastic rocks and those who study carbonates. There is little communication between the two: journals appear which are exclusively devoted to one or the other, and research conferences tend to be mutually exclusive. On the other hand, rocks themselves cannot be "pigeon-holed" in this way - the facies change from clastic to carbonate both laterally and through time. This volume stems from the editors' observations of such changes in the Gulf of Mexico and their realization that these geologically important transitions were being largely ignored because of professional compartmentilization... book opens with a chapter which gives an overview of the whole picture of global patterns of carbonate and clastic sedimentation. It then proceeds to a discussion of sedimentary models of siliciclastic deposits and coral reef relationships. The rest of the book comprises eight case studies on carbonate-clastic transitions, and a final chapter on control of carbonate-clastic sedimentation systems by baroclinic coastal currents.The aim of the book is to emphasize that clastic and carbonate sedimentation are not separate but part of a continuum - a transition which needs to be more thoroughly investigated and better understood. The excellent research papers presented here will undoubtedly help to achieve this goal.

  • Heterocyclic Compounds

    A Modern Comprehensive Treatise
    • 1st Edition
    • Volume G
    • Martin F. Ansell
    • English

  • Animal Virus Structure

    • 1st Edition
    • Volume 3
    • M.V. Nermut + 1 more
    • English
    Animal Virus Structure provides a comprehensive, state-of-the-art summary of the structure, molecular composition, and principal antigenic and biological properties of each currently recognized family of animal viruses. Information deriving from electron microscopy, computer image processing and X-ray diffraction is integrated systematically with biochemical data into three-dimensional molecular models of viral architecture. A brief account of virus/cell interaction and pathogenicity completes each chapter.

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