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Elsevier

Elsevier Science

  • Robust Inference

    • 1st Edition
    • Volume 15
    • Bozzano G Luisa
    • English

  • The Synapse: In Development, Health, and Disease

    • 1st Edition
    • Volume 2
    • B.W. Festoff + 2 more
    • English
    This volume came out of discussions with Professeur Michel Fardeau my long-time colleague in Paris and now Directeur of the Institut de Myologie at the Hopital Pitie-Salpetriere there, and Professeur Emeritus Rene Couteaux, Universite de Paris VI. During my sabbatical year 1994-95, as Professeur de L'Academie des Sciences and Chaire Elf Aquitaine in Paris, Professeur Couteaux and I had a number of discussions, centering on the development of the field of synaptology from his perspective as one who had experienced many of the significant advances during his active professional career. Following these discussions, my colleagues, Daniel Hantai in Paris, and Bruce Citron in Kansas City, and I began to contact scientists in various areas of current synapse research. The result in this volume which seeks to incorporate studies in development, maintenance, and disease states. The foreword by Professeur Couteaux is a remarkable personal journey through the beginnings of this field up to the present day. Professeur Couteaux has continued to be active in his own research on the neuromuscular synapse to this day.

  • Systems, Part A

    • 1st Edition
    • C. Bondy + 1 more
    • English
    This volume deals with some of the multiple systems that growth factors and cytokines affect. The role of growth factors and cytokines on foetal development, in the immune and haemopoietic systems as well as in the skeletal and reproductive systems are covered. Various cancers are examined in a number of the chapters. This is the third and concluding volume of the treatise on growth factors and cytokines in health and disease.

  • Further Milestones in Biochemistry

    • 1st Edition
    • Volume 3
    • M.G. Ord + 1 more
    • English
    The contributors to this text, who are all biochemists who worked during the 1950s and 60s, describe what appears to them to be the conceptually significant developments in biochemistry since the mid 1950s and how these were achieved. Their aim is to make their subjects intelligible to other scientists not expert in their field.

  • Membranes and Cell Signaling

    • 1st Edition
    • Volume 7
    • Edward Bittar
    • English
    It should not come as too much of a surprise that biological membranes are considerably more complex than lipid bilayers. This has been made quite clear by the fluid-mosaic model which considers the cell membrane as a two-dimensional solution of a mosaic of integral membrane proteins and glycoproteins firmly embedded in a fluid lipid bilayer matrix. Such a model has several virtues, chief among which is that it allows membrane components to diffuse in the plane of the membrane and orient asymmetrically across the membrane. The model is also remarkable since it provokes the right sort of questions. Two such examples are: Does membrane fluidity influence enzyme activity? Does cholesterol regulate fluidity? However, it does not go far enough. As it turns out, there is now another version of this model, the so-called post-fluid mosaic model which incorporates two concepts, namely the existence in the membrane of discrete domains in which specific lipid-lipid, lipid-protein and protein-protein interactions occur and ordered regions that are in motion but remain separate from less ordered regions. We must admit that both are intriguing problems and of importance in guiding our thinking as to what the next model might be.We have chosen not to include the subject of membrane transport in the present volume. This obviously represents a break with convention. However, the intention is to have the topic covered subsequent volumes relating to organ systems. It would be right to regard this as an attempt to strengthen the integrated approach to the teaching of medicine.

  • Acid Atmospheric Deposition and its Effects on Terrestrial Ecosystems in The Netherlands

    The Third and Final Phase (1991-1995)
    • 1st Edition
    • Volume 69
    • G.J. Heij + 1 more
    • English
    The book begins with an overview of the research topics which were addressed in the three different phases of the Dutch Priority Program on Acidification (DPPA), executed between 1985 and 1994. This chapter is followed by a chapter which deals with the emissions of acidifying substances, the concentrations and the deposition to forest and nature conservation areas. Prognoses are given for the acid deposition in 2000 and 2010; the deposition in the countries surrounding the Netherlands is also mentioned. The differences in the results of the DPPA-II are analysed.The third chapter deals with the effects of exposure and load on forests. The chapter moves from small-scale to large-scale: first the effects in laboratory-scale studies are described, then the effects in the field, both at stand level and on a regional scale. In addition, the critical thresholds (critical level of concentration and critical load of deposition) are discussed.The fourth chapter covers terrestrial ecosystems (or parts thereof) as well as weakly buffered surface waters, springs and other streams. Critical levels and loads are also discussed. The most important results are given in chapter 5.In the appendices of the book, so-called umbrella theme reports on deposition, stand modelling and effects on forests are presented which describe in more detail the scientific work performed in the third phase of the DPPA.This book will be of interest to anyone involved in research related to acidification and eutrophication; i.e., not only those who perform the research in the causal chain from emissions to effects, but also policy-makers and students.

  • Elsevier's Dictionary of Drug Traffic Terms

    In English, Spanish, Portuguese, French and German
    • 1st Edition
    • N. Illanes
    • English
    This dictionary provides fast and easy access to terms in areas such as: legal, judicial and court proceedings; law enforcement, police and military training; chemical essentials and chemical precursors; natural, synthetic and designer drugs; banking and money laundering. It also presents some related terminology for environmental, medical, psychological, social and economic matters. The dictionary includes a large number of jargon terms, and explanations of these have been provided in some cases, in order to ensure better understanding. This work is an indispensable tool for conference interpreters, court interpreters, translators and social workers.

  • The Primate Nervous System, Part I

    • 1st Edition
    • Volume 13
    • Floyd E. Bloom + 2 more
    • English
    This volume is a new, timely and fitting extension to the Handbook of Chemical Neuroanatomy, focussing on the neurochemical circuitry of the primate brain. The book will compliment the growing efforts to apply the analytical strategies of chemical neuroanatomy to the primate brain.The goal of this volume is to develop a broad-based coverage of human and non-human primate chemical neuroanatomic details together within a volume in which details on transmitters and systems can be appreciated.The eight comprehensive chapters that comprise this volume deal with large global concepts and datasets which not only create an initial coverage of the entire primate neuraxis, but also capture useful points of information on the chemical neuranatomy of the primate nervous system.An excellent, informative book, and a welcome addition to the sparse literature in this field.

  • Biochemical Technology, Part A

    • 1st Edition
    • Volume 15
    • L. Bulow
    • B. Danielsson
    • English
    In December 1992, the Department of Pure and Applied Biochemistry at the Chemical Center in Lund, Sweden, organized an international meeting, the Mosbach Symposium on Biochemical Technology, to celebrate the 60th birthday of professor Klaus Mosbach, one of the founders of modern biotechnology. The history of Pure and Applied Biochemistry had its start in 1970, a couple of years after the foundation of the Chemical Center. Klaus Mosbach has been its professor and head of Pure and Applied Biochemistry since its start. During the 1980's he also maintained a professorship at the ETH in Zürich, Switzerland. Professor Mosbach is internationally well-known and he has world-leading position within the field of immobilization of bioactive substances and cells as well as affinity chromatography. In 1990, Professor Mosbach was awarded the gold medal by the Royal Swedish Academy of Engineering Sciences for his contributions to biotechnology, especially on the immobilization of bioactive substances.The research activities of the Department of Pure and Applied Biochemistry cover a broad area, such as affinity and separation techniques, bioprocess control, biosensors, development of new carriers and new immobilization procedures for small molecules as well as proteins and cells, including animal and plant cells, gene technology, processes based on immobilized biocatalysts, and construction of organic polymers with enzyme-like properties. The hallmark of the department is its diversified research that generates considerable synergistic effects that are manifested by many new techniques and concepts emanating from the laboratory during the last 20 years. Several of these are marketed by various biotechnology companies. At this meeting we therefore arranged for some of the world's leading experts in biochemistry and biotechnology to give lectures. The topics covered comprise enzyme technology, immobilization of enzymes and cells, abzymes, metabolic engineering, biosensors, and molecular recognition. The official gift from the symposium committee and the participants is this "Festschrift" which covers several important fields of research within the area of biochemical technology. We have made a very unusual approach and have let the "hero of the occasion" present the history of his research.

  • Techniques of Scientific Computing (Part 2)

    • 1st Edition
    • Volume 5
    • P.G. Ciarlet
    • English
    This series of volumes aims to cover the major aspects of Numerical Analysis, serving as the basic reference work on the subject. Each volume concentrates on one, two, or three, particular topics. Each article, is an in-depth survey, reflecting the most recent trends in the field, and is essentially self-contained. The handbook covers the basic methods of numerical analysis, under the following general headings: solution of equations in R n; finite difference methods; finite element methods; techniques of scientific computing; and optimization theory and systems science. It also covers the numerical solution of actual problems of contemporary interest in Applied Mathematics.

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