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Academic Press

  • Molecular and Cell Biology

    • 1st Edition
    • Harry Gelboin
    • English
    Polycyclic Hydrocarbons and Cancer, Volume 2: Molecular and Cell Biology explores the link between polycyclic aromatic hydrocarbons (PAHs) and cancer from the viewpoint of molecular and cell biology. This volume consists of 26 chapters divided into eight sections based on the following themes: DNA and Chromatin Interactions; Microbial Mutagenesis; Mammalian Mutagenesis; DNA Repair; Transformation of Cells in Culture; Animal and Human Models; Genetics; and Comments and Observations. The discussion begins with an analysis of the interactions of PAHs with cellular macromolecules and with DNA of mammalian cells in culture. The following chapters focus on microbial and mammalian mutagenesis by PAHs; mechanisms of DNA excision repair in human cells; effect of DNA repair on the cytotoxicity and mutagenicity of PAH metabolites in human cells; and oncogenic transformation of cell cultures by PAHs and their derivatives. The final chapter makes the case for the establishment of a system for conducting quantitative assessments of biomedical risk presented by many types of environmental perturbants such as PAHs. This monograph will be of interest to investigators and educators concerned with scientific aspects of PAH research; government officials and elected representatives as well as industry leaders who must confront and solve the problems related to PAHs; and others in the field of molecular and cell biology.
  • Problems with Temperature Regulation During Exercise

    • 1st Edition
    • Ethan Nadel
    • English
    Problems with Temperature Regulation during Exercise covers the proceedings of the 1976 Problems of Temperature Regulation during Exercise symposium in conjunction with the American College of Sports Medicine meeting, held in Anaheim, California. This book contains seven chapters that consider the various aspects of a specialized problem within the broader area of temperature regulation and exercise physiology. After briefly providing an overview of the temperature regulation during exercise, this text goes on discussing the physical means by which heat is transferred both within the body and between the body and its environment. These topics are followed by a presentation of the physiological systems that control the rates of heat transfer. The subsequent chapters examine the conditions in which the controlling systems are limited in their abilities to transfer heat and to adapt in their capabilities. The remaining chapters explore the specific influences that enhance heat dissipation mechanisms at a given level of central thermoregulatory drive. This work is of great benefit to circulatory physiologists and biophysicists.
  • Radar Target Detection

    Handbook of Theory and Practice
    • 1st Edition
    • Daniel Meyers
    • English
    Radar Target Detection: Handbook of Theory and Practice covers a set of graphical solutions to the detection problem, designated as Meyer Plots, for radar systems design. A radar system's major purpose is the detection and location of an object by means of a return signal, which could be either a reflection or a beacon. This book is composed of four chapters. Chapter 1 presents the basic radar range equation, which is the basic relationship which permits the calculation of echo signal strength from measurable or known parameters of the radar transmitter, antenna, propagation path, and target. Chapter 2 provides examples for determining statistical signal detection using Meyer Plots, particularly for determining detection probability and integration loss and efficiency. Chapter 3 describes the application of target models to determination of detection probability. Chapter 4 examines how Meyer Plots can be used to solve problems involving most any target model.
  • Experimental Quantum chemistry

    • 1st Edition
    • Peter Hedvig
    • English
    Experimental Quantum Chemistry is a comprehensive account of experimental quantum chemistry and covers topics ranging from basic quantum theory to atoms and ions, photons, electrons, and positrons. Nuclei, molecules, and free radicals are also discussed. This volume is comprised of eight chapters and begins with an overview of the basic experiments and ideas leading to the development of quantum theory, with special emphasis on the problems of chemistry. The main properties of electromagnetic radiation are then considered, along with the most important relations of electrons and positrons in chemistry; the quantum theory of isolated atoms and ions; the structure of nuclei and the main applications to organic chemistry; and the chemical structure and reactivity of molecules. The theoretical and experimental aspects of interpreting free radical structures on the basis of the molecular orbital and valence bond theories are also explored. The final chapter is devoted to the chemistry of the organic solid state, paying particular attention to the structure and molecular mobilities of organic solids, collective crystal states (excitons, phonons, and polaritons), energy transfer processes, and reactions in the solid state. This book should be of interest to physicists and organic chemists.
  • Seed Dispersal

    • 1st Edition
    • David R. Murray
    • English
    Seed Dispersal focuses on the mechanics and processes involved in seed dispersal, including its implications in ecology, animal behavior, plant and animal biogeography, speciation, and evolution. The selection first elaborates on the aerial motion of seeds, fruits, spores, and pollen and seed dispersal by water. Discussions focus on seed dispersal by rain, river, and flood, effective seed dispersal by ocean currents compared to other vectors, aerodynamic forces and their effects, and launching and release mechanisms. The text then takes a look at seed dispersal syndromes in Australian Acacia, including inference of dispersal syndromes, seed dispersal syndromes, ecological consequences of seed dispersal, and evolutionary derivation of dispersal syndromes. The publication ponders on seed dispersal by fruit-eating birds and mammals, rodents as seed consumers and dispersers, and seed dispersal in relation to fire. Topics include fire as a dispersal vector, long distance dispersal, granivorous rodents and the fates of seeds, determinants of the fate path, population ecology of seed dispersal, and foraging for fruits. The selection is a valuable reference for researchers interested in the factors involved in seed dispersal.
  • Molecular Biology of RNA Tumor Viruses

    • 1st Edition
    • John Stephenson
    • English
    Molecular Biology of RNA Tumor Viruses deals with the molecular biology and biologic significance of RNA tumor viruses. Methods and procedures with broad application to diverse areas of molecular biology, including cell culture procedures, competition radioimmunoassays, molecular hybridization, oligonucleotide mapping, heteroduplex mapping, and restriction endonuclease techniques, are considered. This book is organized into 12 chapters and begins with a historical overview of tumor virology beginning with the early studies of Peyton Rous and leading up to the significant surge of activity during the later decade. The biology of endogenous retroviruses, their transmission both within and between species, and cellular regulatory factors influencing their expression are subsequently discussed. This book then addresses the nature and origin of transforming RNA viruses and gives a detailed review of knowledge concerning the genomic structure of type C viruses. Translational products encoded by the type C viral genome are examined in ensuing chapters, emphasizing the viral reverse transcriptase. Other mammalian retroviruses, including the mouse mammary tumor virus and type D isolates of primates, are also described. The book concludes by evaluating the possibility of direct etiologic involvement of either endogenous or exogenous RNA tumor viruses in human cancers. This book will be of value both to graduate students and to established investigators with specific interest in other aspects of molecular biology.
  • Meiosis

    • 1st Edition
    • Peter Moens
    • English
    Meiosis is a monograph focused on meiosis-specific functions. It presents a discussion on the genetic regulations of meiosis and aims to direct readers on future research by reporting a number of studies on progress. The text is divided into four parts and consists of 12 chapters. After an introduction to the meiotic process, the first part of the book narrates the genetic transmission and the evolution of reproduction and parthenogenesis. The second part presents the concepts of recombination, the heteroduplex model, and the genetic control of biochemical events in meiotic recombination. The third part covers the information about the chiasmata and synaptonemal complex, including the Rabl orientation. The text is then concluded by the fourth part that covers the biochemical basis of meiosis. The book is an excellent reference for undergraduate and graduate students in biological courses, specifically in genetics, biochemistry, and cell, developmental, and molecular biology. Lecturers, researchers, and other professionals in the same field will also find this book useful.
  • The Platelets

    Physiology And Pharmacology
    • 1st Edition
    • Gesina Longenecker
    • English
    The Platelets: Physiology and Pharmacology is a critical review of the basic platelet systems, methodologic critiques, and platelet involvement in major disease states. This book is composed of 20 chapters that specifically deal with the physiology and biochemistry of the platelet system, along with possibilities for, and consequences of, pharmacologic manipulation. The opening chapters examine the basic processes of platelet aggregation and adhesion. These topics are followed by discussions on the types and functions of platelet α-granule proteins; the aspects of adenine nucleotide levels, regulation, and storage; and receptors for catecholamines and consequences of their agonism. Other chapters are devoted to the metabolism of arachidonic acid, its manipulation, consequences, and metabolite receptors. The discussion then shifts to the second-messenger entities, specifically calmodulin, calcium, and cyclic adenosine monophosphate. A chapter presents the comparisons of man and commonly used laboratory animals concerning platelet behavior variability. Another chapter looks into the use and appropriateness of the use of platelets as models of neurons, with a special emphasis on serotonergic neurons. The remaining chapters contain critical reviews of platelet involvement in diabetes, hypertension and peripheral vascular disease, atherogenesis/athero... and ischemic heart disease. These chapters also include specific techniques for platelet analysis, including lumiaggregometry, eicosanoid measurements, and serotonin uptake and release. This book is an invaluable source for pharmacologists, biochemists, researchers, and clinicians who are interested in platelet involvement in disease.
  • The Geometry of Algebraic Fermi Curves

    • 1st Edition
    • D Gieseker
    • English
    The Geometry of Algebraic Fermi Curves deals with the geometry of algebraic Fermi curves, with emphasis on the inverse spectral problem. Topics covered include the periodic Schrödinger operator and electrons in a crystal; one-dimensional algebraic Bloch varieties; separable Bloch varieties; and monodromy for separable and generic Bloch varieties. Compactification, the potential zero, and density of states are also discussed. This book consists of 13 chapters and begins by recalling the static lattice approximation for electronic motion at low temperature in a pure, finite sample of a d-dimensional crystal. The position of the Fermi energy and the geometry of the Fermi hypersurface in relation to the metallic properties of the crystal are described. The following chapters focus on the Bloch variety associated with a discrete two-dimensional periodic Schrödinger operator; algebraic Bloch varieties in one dimension; compactification of the Bloch variety; and the potential zero. The geometry of the Bloch variety of a separable potential is also considered, along with the topology of the family of Fermi curves. The final chapter demonstrates how the Bloch variety is determined by the density of states. This monograph will be a useful resource for students and teachers of mathematics.
  • Comparative Endocrinology V1

    • 1st Edition
    • U.S. Von Euler
    • English
    Comparative Endocrinology: A Treatise in Two Volumes, Volume I: Glandular Hormones focuses on animal morphology, physiology, and chemistry and systematic and comprehensive account of endocrine principles from the comparative consideration. The selection first offers information on hypothalamic control of anterior pituitary and neurohypophyseal hormones. Discussions focus on adrenocorticotropin, thyrotropin, gonadotropins, physiological significance of the neurohypophyseal hormones in mammals, and physiological significance of the neurohypophyseal hormones in nonmammalian vertebrates. The text then takes a look at pituitary hormones affecting chromatophores and female gonadal hormones. The publication examines male gonadal hormones and adrenocortical hormones. Topics include action of testicular estrogen and ovarian testosterone, source of sex hormones in the male, factors regulating testicular functions, biochemistry of androgens, and functions of the adrenocortical hormones. The book then tackles chromaffin cell hormones, thyroid hormones, and parathyroid glands. The selection is a dependable source of data for readers interested in glandular hormones.