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Academic Press

  • Hepatitis Viruses of Man

    • 1st Edition
    • Arie J. Zuckerman + 1 more
    • T. W. Tinsley + 1 more
    • English
    Hepatitis Viruses of Man covers the advances and developments in the study of viral hepatitis. The book discusses the history, epidemiology, and clinical features of viral hepatitis; the nomenclature and morphology of hepatitis viruses and their antigens; and the pathology of the liver in acute viral hepatitis. The text also describes the biochemical and biophysical properties of hepatitis B surface antigen; the nature and immunopathogenesis of hepatitis B; and the laboratory tests for hepatitis B surface antigen and antibody and hepatitis B core antigen and antibody. The carrier state; maternal transmission of hepatitis B and neonatal infection; and Hepatitis B virus and primary liver cancer are also considered. The book further tackles the laboratory tests for hepatitis A and the nature of the virus; immunization against hepatitis; and interferon and antiviral therapy in chronic hepatitis B infection. Microbiologists, pathologists, and medical doctors will find the book useful.

  • Current Topics in Cellular Regulation

    • 1st Edition
    • Volume 16
    • Bernard L. Horecker + 1 more
    • English
    Current Topics in Cellular Regulation, Volume 16 considers the advances in the general area of cellular regulation. This book discusses the subcellular distribution of hexokinase in brain homogenates and experimental evidence for bound hexokinase as a compartmental control point. The enzymology and biologic significance of cytochrome c methylation, polyaromatic-biosynt... multienzyme system, and proteolytic modulation of gene expression in sporulation are also elaborated. This text likewise covers the occurrence of cyclic nucleotide-synthesiz... and -degrading enzymes in the mammalian brain and calcium ion as a positive effector of oocyte maturation. This volume is beneficial to biologists and researchers conducting work on the basic mechanisms involved in the regulation of diverse cellular activities.

  • Speech and Language

    Advances in Basic Research and Practice
    • 1st Edition
    • Volume 1
    • Norman J. Lass
    • English
    Speech and Language: Volume 1, Advances in Basic Research and Practice is a compendium of papers that discusses the processes and pathologies of, as well as applies theories and clinical issues to, speech and language. Some papers discuss perception of speech in early infancy, the problems faced by speech clinicians, and the anatomy of the perioral motor system. Based on data compiled on the infant's perception of speech sounds, one paper notes that human infants discriminate depending on fine temporal and frequency changes in a complex auditory array. Infants also show perceptual constraints while listening to speech characterized as adult- like; they are also predisposed to perceive certain speech-sound categories such as vowel and fricative categories. One paper examines the suggestion of Kent (1976) that "acoustic characteristics of children's speech...hold the promise of sensitive methods for the study of speech maturation and developmental disorders." This investigation involves the following: the recent attempts at multidimensional analyses of speech and perception; a measure of perceptual contrast; and results of feature comparison efforts. The compendium is well suited for linguists, ethnologists, psychologists, and researchers whose works involve linguistics, language learning, communications, and syntax.

  • Cell Structure and Function by Microspectrofluorometry

    • 1st Edition
    • Elli Kohen
    • English
    Cell Structure and Function by Microspectrofluorome... provides an overview of the state of knowledge in the study of cellular structure and function using microspectrofluorome... The book is organized into six parts. Part I begins by tracing the origins of modern fluorescence microscopy and fluorescent probes. Part II discusses methods such as microspectroscopy and flow cytometry; the fluorescence spectroscopy of solutions; and the quantitative implementation of fluorescence resonance energy transfer (FRET) in the light microscope. Part III presents studies on metabolism, including the mechanism of action of xenobiotics; biochemical analysis of unpigmented single cells; and cell-to-cell communication in the endocrine and the exocrine pancreas. Part IV focuses on applications of fluorescent probes. Part V deals with cytometry and cell sorting. It includes studies on principles and characteristics of flow cytometry as a method for studying receptor-mediated endocytosis; and flow cytometric measurements of physiologic cell responses. Part VI on bioluminescence discusses approaches to measuring chemiluminescence or bioluminescence in a single cell and measuring light emitted by living cells.

  • Agents Unleashed

    A Public Domain Look at Agent Technology
    • 1st Edition
    • Peter Wayner
    • English
    Agents Unleashed: A Public Domain Look at Agent Technology covers details of building a secure agent realm. The book discusses the technology for creating seamlessly integrated networks that allow programs to move from machine to machine without leaving a trail of havoc; as well as the technical details of how an agent will move through the network, prove its identity, and execute its code without endangering the host. The text also describes the organization of the host's work processing an agent; error messages, bad agent expulsion, and errors in XLISP-agents; and the simulators of errors, functions, and resources. Agent language, XLISP, TCL and other languages are also considered. The book further tackles security and encryption; commercial cash; and some ambitious and extreme examples of how people are attempting to create agents. The text also encompasses the instructions on how to use the XLISP agents. Software agents will find the book invaluable.

  • Advances in Lipid Research

    • 1st Edition
    • Volume 22
    • Rodolfo Paoletti + 1 more
    • English
    Advances in Lipid Research, Volume 22 provides information pertinent to the fundamental aspects of lipid research. This book covers a variety of topics, including lipid secretion, lipids in platelet function, lipid transfer proteins, serum cholesterol, and cholesterol metabolism. Organized into five chapters, this volume begins with an overview of the lipid secretion of the meibomian glands, with emphasis on its chemical composition and physical properties. This text then explains the influence of lipids in platelet function and considers the metabolism of arachidonic acid in disease states, such as diabetes, nephrosis, and atherosclerosis. Other chapters examine the manner in which dietary cholesterol contributes to regulation of cholesterol metabolism. This book discusses as well the identification, isolation, and metabolism of sterol carrier proteins and lipid transfer proteins. The final chapter deals with the underlying problems that militate against a simple dose–response relationship. This book is a valuable resource for biologist, biochemists, and clinicians.

  • Current Topics in Cellular Regulation

    • 1st Edition
    • Volume 14
    • Bernard L. Horecker + 1 more
    • English
    Current Topics in Cellular Regulation, Volume 14 reviews the advances in the general area of cellular regulation. This book discusses the mechanism and function of the C4 pathway, regulation of individual enzymes, inhibitors of isoleucine and valine biosynthesis, and patterns of derepression. The functions of 2,3-bisphosphoglycer... 2,3-bisphosphoglycer... in erythrocytes during development; and regulation of glycogen synthetase activity are also elaborated. This publication likewise covers the substrate specificity of cAMP-dependent protein kinase, model systems of enzyme sequences, and posttranslational modifications in selected enzymes. This volume is a good source for biologists and researchers interested in the basic mechanisms involved in the regulation of diverse cellular activities.

  • Ion Transport in Prokaryotes

    • 1st Edition
    • Barry P. Rosen + 1 more
    • English
    Ion Transport in Prokaryotes provides an advance treatise on ion transport and prokaryotic organisms. This book is divided into three main topics—cation transport systems, anion transport systems, and plasmid-encoded transport systems. This compilation specifically discusses the proton transport and proton-motive force in prokaryotic cells, potassium transport in bacteria, and bioenergetic functions of sodium ions. The calcium transport in prokaryotes, phosphate transport in prokaryotes, and transport of organic acids in prokaryotes are also elaborated. This text likewise covers the chloride, nitrate, and sulfate transport in bacteria and bacterial magnesium, manganese, and zinc transport. This publication is recommended for biologists, specialists, and students interested in the bacterial ion transport system.

  • Current Topics in Bioenergetics

    Volume 14
    • 1st Edition
    • C. P. Lee
    • English
    Current Topics in Bioenergetics, Volume 14 provides information pertinent to the structure and function relationship of energy-transducing membranes. This book presents a number of biochemical and biophysical approaches that are valuable in some systems. Organized into five chapters, this volume begins with an overview of cytochrome oxidase, a noncrystallizable membrane protein. This text then determines the interaction of small organic molecules with biological membranes on a molecular level. Other chapters consider the various physical techniques that are used to investigate the structural and dynamic properties of proteins, lipids, and membranes, including neutron diffraction, X-ray diffraction, electron microscopy, optical rotatory dispersion, nuclear magnetic resonance, fluorescence spectroscopy, and Raman spectroscopy. This book discusses as well the biological importance of metal ions. The final chapter deals with optical activity spectroscopy as a recognized tool for the examination of the conformation of biological macromolecules. This book is a valuable resource for biochemists, biophysicists, and biologists.

  • Cholinergic Ligand Interactions

    • 1st Edition
    • D. J. Triggle + 2 more
    • English
    Cholinergic Ligand Interactions presents the papers read at a symposium held at the State University of New York at Buffalo, 25-26 May 1970. The recent purification and crystallization of acetylcholinesterase together with real progress in the purification of receptor components indicated the desirability of organizing a symposium to discuss not only these aspects but also the structural bases for cholinergic ligand interaction with these macromolecules, the conformational changes involved with ligand binding, the quantitation of cholinergic ligand binding sites, and the roles of acetylcholinesterase and its isozymes in muscle disease. The volume contains nine chapters and begins with a study on possible conformational changes in acetylcholinesterase... This is followed by separate chapters on the subunits of acetylcholinesterase... in vitro studies with the cholinergic receptor of the eel electroplax; identification and isolation of acetylcholine receptors; assay and properties of essential (junctional) cholinesterases of the rat diaphragm; and structural variations in cholinergic ligands. Subsequent chapters deal with ligand interactions at the muscarinic receptors and changes in cholinesterases isozymes during normal and dystrophic muscle development.

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