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Academic Press

  • Planning and Design of Information Systems

    • 1st Edition
    • André Blokdijk
    • English
    Planning and Design of Information Systems provides a theoretical base and a practical method of executing the planning of computerized information systems, and the planning and design of individual applications. The book is organized into five parts, covering the non-technical and nonimplementational part of information systems planning, design, and development. Part I gives the theoretical base for the subsequent parts of the book. It discusses modeling, techniques, notations, boundaries, quality issues and aspects, and decomposition techniques and problems. Part II discusses the needs, problems, and possible solutions for user participation. It describes user organizations, in respect of culture; maturity in the use of automation and computers; and gives a synthesis of participation, cultures, maturity, and information systems development techniques. Part III describes how to develop an Information Systems Architecture, an Information Systems Plan, and a Data Architecture. Part IV presents a structured, programmed approach to planning an application in a short period while maintaining high quality, and discusses project management of application development. Part V covers information analysis, data specification and conceptual data base design, and process and dialog design.
  • Current Topics in Cellular Regulation

    • 1st Edition
    • Volume 17
    • Bernard L. Horecker + 1 more
    • English
    Current Topics in Cellular Regulation, Volume 17 deals with the basic mechanisms involved in the regulation of diverse cellular activities. This book discusses the regulation of proteinase inhibitor accumulation in excised tomato leaves, inhibitors associated with cysteine proteinases, and stimulation of DNA synthesis in quiescent cultured cells. The regulation of the biosynthesis of RNA polymerase subunits, molecular consequences of formyl peptide binding, and instability versus homeostasis in cell energy metabolism are also elaborated. This text likewise covers the physiological significance of desensitization and cooperation between nuclear and mitochondrial genetic systems. This volume is beneficial to biologists and researchers concerned with advances in the general area of cellular regulation.
  • Immunological Tolerance

    A Reassessment of Mechanisms of the Immune Response
    • 1st Edition
    • Maurice Landy + 1 more
    • English
    Immunological Tolerance: A Reassessment of Mechanisms of the Immune Response presents the basic biological phenomena of immunological tolerance. This book discusses immunology as a critical field for the analysis of molecular features of mammalian cell genetics, biosynthesis, differentiation, and interactions among cell types. Organized into six chapters, this book begins with an overview of the relationship between antigen structure and its ability to induce tolerance. This text then examines the essentiality of antigen for the proliferation of activated antibody-forming clones and discusses the role of antibody in homeostasis and suppression. Other chapters consider the restoration and transfer of immunological responsiveness by thoracic duct lymphocytes. This book discusses as well the distribution of antigen in tissues and cells. The final chapter deals with the origin of carrier antibody and the significance of maternal transfer of antibodies and antigens. This book is a valuable resource for immunologists, microbiologists, scientists, and clinicians.
  • Nucleotide Metabolism

    An Introduction
    • 1st Edition
    • J. Frank Henderson + 1 more
    • English
    Nucleotide Metabolism: An Introduction is a textbook exclusively focusing on the study of the aspects of nucleotide metabolism. The book intends to present the chemistry and metabolism of nucleotides, one of the oldest subjects of biochemistry. The text is divided in two parts. Part I considers the general aspects of nucleotide metabolism such as the history of the discovery of nucleotides; functions of nucleotides in cells; and group-transfer reactions during nucleotide metabolism. Part II deals with the synthesis, formation, and conversion of purine ribonucleotides. Biochemists, pharmacologists, and researchers in the fields of medicine and pharmaceuticals will find the book invaluable.
  • Structure and Function of Biological Membranes

    • 1st Edition
    • Lawrence I. Rothfield
    • English
    Structure and Function of Biological Membranes explains the membrane phenomena at the molecular level through the use of biochemical and biophysical approaches. The book is an in-depth study of the structure and function of membranes. It is divided into three main parts. The first part provides an overview of the study of the biological membrane at the molecular level. Part II focuses on the detailed description of the overall molecular organization of membranes. The third part covers the relationship of the molecular organization of membranes to specific membrane functions; discusses catalytic membrane proteins; presents the role of membranes in important cellular functions; and looks at the membrane systems in eukaryotic cells. Biochemists, cell physiologists, biologists, researchers, and graduate and postdoctoral students in the field of biology will find the text a good reference material.
  • Advances in Lipid Research

    • 1st Edition
    • Volume 9
    • Rodolfo Paoletti + 1 more
    • English
    Advances in Lipid Research, Volume 9 is a seven-chapter text that highlights the advances in methodology to steroid chemistry. The opening chapter describes the important aspect of autoradiography and its coupling with light and electron microscopic analysis. The next chapters deal with the carbon source in the fatty acid biosynthesis, with particular emphasis on the biosynthesis by the aortic the issue. These topics are followed by discussions of the membrane structure and the lipids in membranes. Other chapters consider the biochemistry and analysis of glycosphingolipids and the progress in the in lipid chemistry, including pregnane derivatives and C21 steroids. The concluding chapter reviews the composition of vegetable oil and other aspects of fat metabolism, specifically cholesterol metabolism. This book will prove useful to lipid chemists, biochemists, and organic chemists.
  • Advances in Lipid Research

    • 1st Edition
    • Volume 10
    • Rodolfo Paoletti + 1 more
    • English
    Advances in Lipid Research, Volume 10 is a six-chapter text that is devoted to several special areas of lipid research, including significant progress in established areas of interest in the field. The introductory chapter surveys the application of electron microscopic techniques to the analysis of plasma lipoproteins. The subsequent chapter deals with the possible modification of reticuloendothelial functions by lipids and the role of lipids in cellular, humoral, and immune responses. These topics are followed by discussions of the microsomal enzymes of sterol biosynthesis and the enzymatic synthesis and degradation of glycerol lipids, which contain ether bonds. The remaining chapters focus on lipid neurochemistry. These chapters specifically examine particular brain lipids, such as fatty acids, phospholipids, sphingolipids, galatosyl lipids, and sterols. A discussion of lipids of the entire nervous system and their variation with age is also included. This book will prove useful to lipids chemists, biochemists, and organic chemists.
  • Map Data Processing

    Proceedings of a NATO Advanced Study Institute on Map Data Processing Held in Maratea, Italy, June 18–29, 1979
    • 1st Edition
    • Herbert Freeman + 1 more
    • English
    Map Data Processing is a collection of papers from a NATO study on the same subject. This collection deals with the exchange of ideas and setting directions in research, particularly in pattern-recognition-... image-processing-, and computer-related issues. The papers discuss the usefulness of computer systems in geographical data processing, as well as the viability of scan digitization resulting from improvements in line thinning and vectorization. Automated spatial data integration can also be helpful in analyzing spatial data, data collection, capture methods, and data characteristics. Another paper addresses the application of the 8-point chain-encoded lineal map data to define more accurate algorithms found in many geographical and medical imagery. One paper considers how the same data used in monochromatic images can be realized for full colored, textured, realist terrain scenes. This book can be a valuable reference for workers involved in areas of geography, computer imaging, cartography, computer graphics, and remote sensing.
  • Maya Subsistence

    Studies in Memory of Dennis E. Puleston
    • 1st Edition
    • Kent V. Flannery
    • English
    Maya Subsistence: Studies in Memory of Dennis E. Puleston presents studies on the history and development of Maya subsistence in honor of Maya archaeologist Dennis E. Puleston (1940-1978). The discussions are organized around four themes: ecological models for early Maya adaptations; archaeological investigations of Pre-classic and classic Maya subsistence; contributions of geography and soil science to an understanding of ancient Maya subsistence; and Maya subsistence in the post-classic, colonial, and modern eras. Comprised of 15 chapters, this book begins with an analysis of Puleston's career and a review of the history of inquiry into Maya subsistence. Maya subsistence from the earliest Pre-classic period up to the present day is then examined, with emphasis on agriculture, hunting, wild plant collecting, animal husbandry, and trade. In particular, cultural development in the Valley of Guatemala from 1500 B.C. to the Spanish Conquest is discussed, along with the resources of the tropical lowlands and actual prehistoric cornfields miraculously preserved by volcanic ashfall in El Salvador. The book also presents evidence for Maya soil and water conservation over the entire area from Yucatan to Chiapas and central Guatemala, and looks at the traditional role of women and animals in lowland Maya economy. This monograph will be of interest to archaeologists and anthropologists.
  • Recent Progress of Life Science Technology in Japan

    • 1st Edition
    • Yoji Ikawa + 1 more
    • English
    Recent Progress of Life Science Technology in Japan discusses developments in cancer research technologies in Japan. In June 1983 an intra-cabinet panel of the Japanese Government drafted a 10-year strategy for cancer control, recognizing the importance of this field of research. A scientific research group was organized to comprise two sections—the first concerning the development and evaluation of DNA technologies, and the second on protein-related technologies. In the promotion of fundamental cancer research, the development and refinement of basic technologies for each component of the ""triangle of bio-sciences""—DNA, protein, and antibody—are essential, particularly in the elucidation of tumor-inducing and tumor-suppressing genes, tumor-specific antigens, and so forth. Part I of the book details the achievements of the first group in developing automated instrumentations for DNA sequencing. The second scientific research group worked on three major subareas: (1) gene transfer and expression technologies; (2) technologies for extraction, purification, and structural analysis of cancer-related proteins; and (3) technologies for analysis and synthesis of saccharide chains. Reports from these areas are respectively grouped in Part II, Part III, and Part IV of this monograph.