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Academic Press

  • Molecular Biology of Placental Development and Disease

    • 1st Edition
    • Volume 145
    • English
    Molecular Biology of Placental Development and Disease, the latest volume in the Progress in Molecular Biology and Translational Science series, focuses on placental development and disease.

  • Polycomb Group Proteins

    • 1st Edition
    • Vincenzo Pirrotta
    • English
    Polycomb Group Proteins is a comprehensive volume detailing the mechanisms that are key to the management of genome function in many different contexts, from embryonic stem cells to terminal differentiation. The book discusses the regulation of cell lineages, cell proliferation, apoptosis, X chromosome inactivation, and most major genome programming choices. In the last few years, the biochemical understanding of PRC1-type complexes has greatly expanded in terms of the number of components involved and the intricacies of their interactions. The functionalities of these various complexes and their components are not all well understood, but recent work has shown an important division of labor and roles in the recruitment of stable binding in the ability to lay the groundwork of histone modifications and in the epigenetic maintenance of repressed states. In an effort to provide clarity in this topical research area, the book provides a cluster of chapters that deal with variant PRC1 complexes, their taxonomy, their components, their interactions, and what is known of their functions.

  • Handbook of Cannabis and Related Pathologies

    Biology, Pharmacology, Diagnosis, and Treatment
    • 1st Edition
    • Victor R. Preedy
    • English
    Handbook of Cannabis and Related Pathologies: Biology, Pharmacology, Diagnosis, and Treatment is the first book to take an interdisciplinary approach to the understanding of cannabis use and misuse. Recent worldwide trends toward decriminalizing marijuana for medical use have increased legal use of the drug and recreational use remains high, making cannabis one of the most commonly used drugs.Cannabis has a wide range of adverse neurological effects, and use and abuse can lead to physical, social, and psychopathological issues that are multifarious and complex. Effective understanding and treatment requires knowledge of the drug’s effects from across scientific disciplines.This book provides an overview of the biological and pharmacological components of the cannabis plant, outlines its neurological, social, and psychopathological effects, assists in the diagnosis and screening for use and dependency, and aids researchers in developing effective treatments for cannabis-related issues and disorders.Fully illustrated, with contributions from internationally recognized experts, it is the go-to resource for neuroscientists, pharmacologists, pathologists, public-health workers, and any other researcher who needs an in-depth and cross-disciplinary understanding of cannabis and its effects.

  • Translating Epigenetics to the Clinic

    • 1st Edition
    • Jeffrey Laurence
    • English
    Translating Epigenetics to the Clinic reviews current methodological tools and experimental approaches used by leading translational researchers seeking to use epigenetics as a clinical model. It organizes epigenetics into disease treatment areas with a major focus on oncology, and with much coverage of pervasive treatment categories such as diabetes, as well as the ‘diseases of modernity’—including pharmacological addiction, dementia, and ageing. Pedagogically, the work concentrates on the latest knowledge, laboratory techniques, and experimental approaches used by translational research leaders in this field. The book promotes cross-disciplinary communication between the sub-specialties of medicine. In common with the rest of the books in Translational Medicine, the book remains unified in theme by emphasizing recent innovations, critical barriers to progress, and the new tools being used to overcome them. Also includes specific areas of research that require additional study to advance the field as a whole.

  • Inorganic and Organometallic Transition Metal Complexes with Biological Molecules and Living Cells

    • 1st Edition
    • Kenneth Kam-Wing Lo
    • English
    Inorganic and Organometallic Transition Metal Complexes with Biological Molecules and Living Cells provides a complete overview of this important research area that is perfect for both newcomers and expert researchers in the field. Through concise chapters written and edited by esteemed experts, this book brings together a comprehensive treatment of the area previously only available through scattered, lengthy review articles in the literature. Advanced topics of research are covered, with particular focus on recent advances in the biological applications of transition metal complexes, including inorganic medicine, enzyme inhibitors, antiparasital agents, and biological imaging reagents.

  • Forensic Anthropology

    • 1st Edition
    • Max M. Houck
    • English
    Forensic Anthropology serves as a graduate level text for those studying and teaching forensic anthropology, as well as an excellent reference for forensic anthropologist libraries or for use in casework. Covers taphonomy, recovery and analysis, identification, statistical interpretation, and professional issues. Edited by a world-renowned leading forensic expert, the Advanced Forensic Science Series grew out of the recommendations from the 2009 NAS Report, Strengthening Forensic Science: A Path Forward, and is a long overdue solution for the forensic science community.

  • Creativity and the Performing Artist

    Behind the Mask
    • 1st Edition
    • Paula Thomson + 1 more
    • English
    Creativity and the Performing Artist: Behind the Mask synthesizes and integrates research in the field of creativity and the performing arts. Within the performing arts there are multiple specific domains of expertise, with domain-specific demands. This book examines the psychological nature of creativity in the performing arts. The book is organized into five sections. Section I discusses different forms of performing arts, the domains and talents of performers, and the experience of creativity within performing artists. Section II explores the neurobiology of physiology of creativity and flow. Section III covers the developmental trajectory of performing artists, including early attachment, parenting, play theories, personality, motivation, and training. Section IV examines emotional regulation and psychopathology in performing artists. Section V closes with issues of burnout, injury, and rehabilitation in performing artists.

  • Neuroprotection in Alzheimer's Disease

    • 1st Edition
    • Illana Gozes
    • English
    Neuroprotection in Alzheimer’s Disease offers a translational point-of-view from both basic and clinical standpoints, putting it on the cusp for further clinical development with its emphasis on nerve cell protection, including the accumulation of knowledge from failed clinical trials and new advances in disease management. This book brings together the latest findings, both basic, and clinical, under the same cover, making it easy for the reader to obtain a complete overview of the state-of-the-field and beyond. Alzheimer's disease is the most common form of dementia, accounting for 60 to 80 percent of dementia cases. It is a progressive brain disease that slowly destroys memory, thinking skills, and eventually, even the ability to carry out the simplest tasks. It is characterized by death of synapses coupled to death nerve cells and brain degeneration which is manifested by loss of cognitive abilities. Understanding neuroprotection in Alzheimer’s disease will pave the path to better disease management and novel therapeutics.

  • Essentials of Medicolegal Death Investigation

    • 1st Edition
    • Matthew M. Lunn
    • English
    Essentials of Medicolegal Death Investigation uses a unique approach by combining medical issues, injury patterns, and investigative procedures to provide the reader with the basic fundamentals for a death investigation. The text introduces the reader to death investigation, common causes of death, and very specific types of death, including blunt-force injuries, gunshot wounds, and toxicology deaths. Each section includes case studies with written and visual descriptions. Written by a well-known and experienced medicolegal death investigator, the book fills a void in medicolegal literature for both students and professionals alike.

  • Forest Management and Planning

    • 2nd Edition
    • Pete Bettinger + 3 more
    • English
    Forest Management and Planning, Second Edition, addresses contemporary forest management planning issues, providing a concise, focused resource for those in forest management. The book is intermixed with chapters that concentrate on quantitative subjects, such as economics and linear programming, and qualitative chapters that provide discussions of important aspects of natural resource management, such as sustainability. Expanded coverage includes a case study of a closed canopy, uneven-aged forest, new forest plans from South America and Oceania, and a new chapter on scenario planning and climate change adaptation.

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