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Academic Press

  • The Microbiome and Cancer Treatment

    Overcoming Resistance and Enhancing Efficacy
    • 1st Edition
    • Sadhna Aggarwal + 3 more
    • English
    The Microbiome and Cancer Treatment: Overcoming Resistance and Enhancing Efficacy delves into the intricate relationship between the microbiome and cancer treatment, highlighting the microbiome's critical role in drug resistance and therapeutic efficacy. The book's chapters are meticulously organized to provide a deep understanding of how the microbiome interacts with the immune system and influences cancer development and response to therapies. This book opens new avenues for investigation by providing a better understanding of the mechanisms of resistance and the role of microbiome alterations in chemoresistance.Sect... also address the complex "chicken-or-egg" relationship between microbiome alterations and chemoresistance. A diverse blend of chapters foster interdisciplinary collaboration across fields such as immunology, microbiology, oncology, and pharmacology, promoting holistic approaches to cancer treatment. Readers will benefit by gaining awareness and a better understanding of how the microbiome impacts health, particularly in the context of cancer, leading to more informed health choices.
  • The Roadmap of Research

    A Guide to Understanding and Writing a Medical Study
    • 1st Edition
    • Vincenzo Giordano + 3 more
    • English
    The Roadmap of Research: A Guide to Understanding and Writing a Medical Study helps readers easily grasp the context, methodologies, findings, and implications of research studies, build on previous work, avoid redundancies, and identify areas where new studies can contribute significantly. The book enables researchers to innovate, propose new ideas, and design studies that contribute novel perspectives or methodologies to the field. Each step in this roadmap plays a pivotal role in the research process, from building a foundation of knowledge through reading and understanding, to generating new ideas through critical thinking, and finally, disseminating findings through clear and effective writing.
  • Security and Privacy in Trustworthy 6G

    A Physical Layer Perspective
    • 1st Edition
    • Christos Masouros + 1 more
    • English
    Security and Privacy in Trustworthy 6G: A Physical Layer Perspective gives a comprehensive overview of fundamental principles and cutting-edge techniques, equipping the reader with a deep understanding of the underlying concepts and techniques in trustworthy 6G. The book provides guidance on practical implementation in areas such as secure precoding, secure waveform, power efficient secure techniques, and data/sensing security issues in ISAC. Additionally, the book explores diverse security requirements in applications, including data security, computing security, sensing security, and user anonymity, making it relevant for researchers, engineers, and practitioners in various domains.
  • Histone Deacetylases in Neurodegenerative Disease Part B

    • 1st Edition
    • Volume 734
    • English
    Histone Deacetylases in Neurodegenerative Disease, Part B, Volume 734 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on timely topics surrounding the Interaction of HDAC6 ZnF UBP with Tau affects its stability by NMR and Simulation studies, Protocols for In Vitro Analysis of Liquid-Liquid Phase Separation of Proteins, Histone deacetylases in NS, Histone Deacetylase 6 ZnF UBP domain enhances podosome formation in neuronal cells studied by high-resolution confocal microscopy, Methodological approach to Investigate Peroxiredoxin 1 Deacetylation by Histone Deacetylase 6, Critical structural features of HDAC11 inhibitors, and much more.Additional chapters in this release include Histone Deacetylases 1 and 2 Regulate Microglia Function during Development, Homeostasis, and Neurodegeneration, Elucidation of Site-Specific Ubiquitination on Chaperones in Response to Mutant Huntingtin, Protein acetylation dynamics (histone and non-histone) and role protein deacetylases in disease, Epigenetic Clues: Predicting Maternal Depression Through DNA Methylation, A short guide on in vivo transfection of flag-HDAC4 in dentate gyrus for study of adult neurogenesis in brain trauma, Decoding the Acetylation Journey from Neural Crest to Melanocyte, and more.
  • Chromatin Signaling and Diseases

    • 2nd Edition
    • Olivier Binda + 2 more
    • English
    Chromatin Signaling and Diseases, Second Edition, a volume in the Translational Epigenetics series, covers the molecular mechanisms that regulate gene expression, which governs embryonic development, growth, and human pathologies associated with aging, such as cancer. Although human genome sequencing continues to improve, molecular mechanisms regulating gene expression remain largely misunderstood. The impact of gene expression defects associated with malfunctioning chromatin signaling are considered in this update. In addition, this new edition has addresses developments in the field, from phase separation of membrane-less organelles and local segregation of factors to chromatinization of naked foreign DNA and cancer evolution as regulated by chromatin signaling.Chromatin signaling proposes that small protein domains recognize chemical modifications on the genome scaffolding histone proteins, facilitating the nucleation of enzymatic complexes at specific loci that then open up or shut down the access to genetic information, thereby regulating gene expression. The addition and removal of chemical modifications on histones, as well as the proteins that specifically recognize these are also considered.
  • Autophagy – Part B

    • 1st Edition
    • Volume 404
    • English
    Autophagy Part B provides an in-depth exploration of advanced mechanisms, functions, and roles of autophagy in health and disease. This volume features contributions from leading experts, covering recent developments in autophagy research, its implications in cellular homeostasis, neurodegeneration, cancer, immunity, and therapeutic strategies. Designed for researchers, clinicians, and students, the book offers valuable insights into the complexities and applications of autophagy in modern biomedical science.
  • Progress in Optics

    • 1st Edition
    • Volume 71
    • English
    Progress in Optics, Volume 71 in this ongoing series, presents the latest release in this renowned serial publication that provides comprehensive, authoritative reviews on significant developments in the field of optical science and engineering. Chapters in this new release include updates on Phased-array lidar, Holographic metasurfaces, The Talbot effect, Space-time optics, Structured Light in Space and Time: Enabling Applications Across Linear, Nonlinear, and Quantum Domains, RIKEN Center for Advanced Photonics, Metaphotonics Research Team, Weak quantum measurements, and Structured Light.Each volume in this series brings together contributions from leading experts, covering a wide range of topics, including classical optics, quantum optics, nonlinear optics, optical materials, photonics, laser technology, imaging systems, and emerging applications.
  • Advances in the Study of Behavior

    • 1st Edition
    • Volume 58
    • English
    A scholarly, annual volume in the field of behavior science that brings together cutting-edge research and theoretical advances. Each edition surveys the latest findings across learning, conditioning, memory, perception, decision making, and related areas, often blending behavioral analysis with neuroscience, genetics, and computational modeling. It features review chapters, original research, and conceptual perspectives aimed at researchers, graduate students, and clinicians seeking a comprehensive, up-to-date understanding of behavior and its underlying mechanisms.
  • Brain Energy Metabolism in Alzheimers Disease - Part C

    • 1st Edition
    • Volume 188
    • English
    Brain Energy Metabolism in Alzheimer’s Disease – Part C, Volume 188 in the International Review of Neurobiology series, presents the latest research on metabolic dysfunction and its role in neurodegenerative diseases. This volume brings together contributions from an international panel of experts, exploring the molecular, cellular, and systemic aspects of energy metabolism in Alzheimer’s disease and related disorders.Chapters in this release examine metabolic therapeutic targets in Alzheimer’s disease, alterations in brain energy metabolism in comparison with Parkinson’s disease, and the role of epigenetic modulation through natural compounds. Additional sections address mitochondrial dysfunction, disruption of metabolic pathways, and the contribution of glial cells to neurodegenerative processes.Further contributions explore metabolic disorders linked to Parkinson’s disease, signaling pathways in neurodegeneration, and advances in therapeutic and diagnostic strategies targeting key enzymes. The volume also highlights the role of intestinal microbiota, nanocarrier-based therapeutic approaches, and emerging treatments such as HDAC inhibitors. Together, these chapters provide a comprehensive overview of the mechanisms, biomarkers, and therapeutic prospects related to energy metabolism in neurodegenerative diseases, making this volume an essential reference for researchers and clinicians in neuroscience and neurobiology.
  • Epigenetic Therapy by Phytochemicals in Lung Cancer

    Mechanisms, Therapeutic Potential, and Clinical Implications
    • 1st Edition
    • Umesh Kumar + 3 more
    • English
    Epigenetic Therapy by Phytochemicals in Lung Cancer provides a comprehensive exploration of the intersection between cancer epigenetics and phytotherapy, focusing on lung cancer. The book emphasizes the role of epigenetic alterations in cancer progression and presents phytochemicals as promising agents capable of reversing these changes, thereby offering innovative therapeutic strategies. The content examines the mechanisms by which epigenetic modifications, such as DNA methylation and histone modification, contribute to lung cancer. It details specific phytochemicals—like curcumin, resveratrol, and quercetin—and their potential to modulate these pathways, while discussing clinical applications, challenges, and future research directions. For academics, this book equips researchers and healthcare professionals with evidence-based insights into alternative cancer therapies, enhancing understanding of multi-targeted approaches. It serves as a valuable reference for teaching and further research, promoting a more inclusive perspective in cancer care and addressing disparities in treatment access and efficacy.