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Academic Press

  • Encyclopedia of Animal Behavior

    • 2nd Edition
    • Jae C. Choe
    • English
    Encyclopedia of Animal Behavior, Second Edition, Four Volume Set the latest update since the 2010 release, builds upon the solid foundation established in the first edition. Updated sections include Host-parasite interactions, Vertebrate social behavior, and the introduction of ‘overview essays’ that boost the book's comprehensive detail. The structure for the work is modified to accommodate a better grouping of subjects. Some chapters have been reshuffled, with section headings combined or modified.
  • Alzheimer’s Disease Theranostics

    • 1st Edition
    • Magisetty Obulesu
    • English
    Alzheimer’s Disease Theranostics discusses the latest information on recent theranostic avenues for both the diagnosis and treatment of Alzheimer’s patients. It presents the pros and cons of the probable mechanistic role of nanoparticles in crossing the blood-brain barrier and improving disease symptoms. Finally, it highlights the merits of existing maneuvers and suggests perspectives to aid in future developments. Despite the difficulty of drug delivery to the brain, there are some nanoparticulate platforms demonstrating promise in treating neurodegenerative disorders such as Alzheimer’s disease. Manifold theranostic maneuvers include antioxidants, natural bioactive compounds, gene therapy, and nanotechnological approaches, all of which are discussed in this important work.
  • AGO-Driven Non-Coding RNAs

    Codes to Decode the Therapeutics of Diseases
    • 1st Edition
    • Bibekanand Mallick
    • English
    The ‘RNA world’ hypothesis that proposed RNA molecules as the first form of genetic material was put forwarded in the late 1980s but got impetus only recently when high-throughput sequencing technologies began unearthing new types of non-coding RNA (ncRNA) transcripts in higher eukaryotes. Till then, research on ncRNAs were primarily confined to transfer RNAs and, ribosomal RNAs, which act as the messengers of the protein synthesis and allow translation of genetic information encoded by DNA into proteins. In recent years, the integration of high-throughput genomic technologies with molecular biology and omics sciences have revolutionized the fields of ncRNA research by identifying the hidden treasures of several new types of ncRNAs encoded in the genomes of several organisms and decrypting their versatile roles in gene expression and epigenetics. Among these, two small endogenous ncRNAs, namely microRNAs (miRNAs) and piwi-interacting RNAs (piRNAs) that drive argonaute (AGO) family of proteins namely Ago and Piwi respectively and silence the expression of genes have geared up molecular and disease biology research in recent years. Both miRNAs and piRNAs are expressed in higher eukaryotes, including human and act as cellular rheostats by regulating the expression of significant fraction of genes encoded in the genomes. The aberrant expressions of these small ncRNAs within the cells cause various abnormalities and diseases including cancer. Manipulating their aberrant expression or function can serve as potential novel diagnostic/prognosti... biomarkers and bring in new therapeutic strategies for multiple human diseases. This can be further translated from bench-side to clinic for improving human health. This book captures the essence of the pioneering work of some of the world’s leading researchers showcasing the scientific excitements surrounding the evolving regulatory roles of miRNAs and piRNAs highlighting their potential towards the diagnosis and therapeutics of various diseases. The book is geared towards scientists, students, and will particularly appeal to active investigators in RNA biology, molecular biology, cancer research as well as clinicians and will provide them a comprehensive view of recent discoveries and research progresses to utilize miRNAs, piRNAs and their interacting proteins, Ago and Piwi for diagnosis, prognosis and therapeutics of diseases.
  • Imaging in Movement Disorders: Imaging in Movement Disorder Dementias and Rapid Eye Movement Sleep Behavior Disorder

    • 1st Edition
    • Volume 144
    • English
    Imaging in Movement Disorders: Imaging in Movement Disorder Dementias and Rapid Eye Movement Sleep Behavior Disorder, Volume 144 provides an up-to-date textbook on the use of imaging modalities across the spectrum of movement disorders and dementias. The book brings together lessons learned from neuroimaging tools in the content of movement disorders, including chapters on Molecular Imaging of Dementia with Lewy Bodies, Structural and Functional Magnetic Resonance Imaging of Dementia with Lewy Bodies, Network Imaging in Parkinsonian and Other Movement Disorders: Network Dysfunction and Clinical Correlates, Neuroimaging of Rapid Eye Movement Sleep Behavior Disorder, Hybrid PET-MRI Applications in Movement Disorders, and more.
  • Sound and Action in Music Performance

    • 1st Edition
    • Peter Q. Pfordresher
    • English
    Sound and Action in Music Performance addresses how auditory feedback influences the planning and execution of our movements. Focusing specifically on auditory feedback in music, including instrumental and vocal production, the book also gives substantial coverage to its role in speech. Both of these behaviors are the primary means by which people communicate their thoughts and feelings through the auditory modality, with auditory feedback being critical in each case. The book proposes that the role of auditory feedback emerges from the broader theme of coordination as our brain coordinates planned actions with concurrent perceptual events, including auditory feedback and other intrusive sounds. Critically reviewing the existing literature and proposing hypotheses for future research, this book tackles a topic that has intrigued researchers for decades.
  • The Impact of Nutrition and Statins on Cardiovascular Diseases

    • 1st Edition
    • Ioannis Zabetakis + 2 more
    • English
    The Impact of Nutrition and Statins on Cardiovascular Diseases presents a summary of the background information and published research on the role of food in inhibiting the development of cardiovascular diseases. Written from a food science, food chemistry, and food biochemistry perspective, the book provides insights on the origin of cardiovascular diseases, an analysis of statin therapy, their side effects, and the role of dietary intervention as an alternative solution to preventing cardiovascular diseases. It focuses on the efficacy of nutrition and statins to address inflammation and inhibit the onset of disease, while also providing nutrition information and suggested dietary interventions.
  • IFRS 9 and CECL Credit Risk Modelling and Validation

    A Practical Guide with Examples Worked in R and SAS
    • 1st Edition
    • Tiziano Bellini
    • English
    IFRS 9 and CECL Credit Risk Modelling and Validation covers a hot topic in risk management. Both IFRS 9 and CECL accounting standards require Banks to adopt a new perspective in assessing Expected Credit Losses. The book explores a wide range of models and corresponding validation procedures. The most traditional regression analyses pave the way to more innovative methods like machine learning, survival analysis, and competing risk modelling. Special attention is then devoted to scarce data and low default portfolios. A practical approach inspires the learning journey. In each section the theoretical dissertation is accompanied by Examples and Case Studies worked in R and SAS, the most widely used software packages used by practitioners in Credit Risk Management.
  • Advances in Heterocyclic Chemistry

    • 1st Edition
    • Volume 127
    • English
    Advances in Heterocyclic Chemistry, Volume 127, the latest release in this definitive series in the field highlights the areas where biology and organic chemistry increasingly intersect. This updated volume includes chapters on The Pictet-Spengler Reaction (1990-2017): A Powerful Strategy for the Synthesis of Heterocycles, Organometallic Complexes of Polyazines, Recent Developments in the Chemistry of Boron- dipyrromethene (BODIPY) Fluorescent Dyes and their Aza analogues, Reactions of 3-Pyrrolin-2-ones, Arsole, Stibole, Bismole, and fused systems , The Chemistry of Dihydrothienopyrrolo... the Application of the Baylis-Hillman Reaction in Heterocyclic Chemistry, and 5-Endo Cyclisation, amongst other topics.
  • Molecular Physiology and Biotechnology of Trees

    • 1st Edition
    • Volume 89
    • English
    Molecular Physiology and Biotechnology of Trees, Volume 89 in the Advances in Botanical Research series, highlights new advances in the field, with this new volume presenting interesting chapters on such topics as the Activity of the shoot apical and cambial meristems: Coordination and responses to environmental signals, Conifer functional genomics, Nitrogen storage and cycling, Tree defense against pests and pathogens, The ectomycorrhizal contribution to tree nutrition, Phytoremediation with trees, Transcriptional regulation of wood formation, Transgenic poplars, the Genomics of forest trees, and much more.
  • Stress: Physiology, Biochemistry, and Pathology

    Handbook of Stress Series, Volume 3
    • 1st Edition
    • George Fink
    • English
    Approx.406 pages