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  • Therapeutic Application of Nitric Oxide in Cancer and Inflammatory Disorders

    • 1st Edition
    • Lucia Morbidelli + 1 more
    • English
    Therapeutic Application of Nitric Oxide in Cancer and Inflammatory Disorders presents updated reviews on the chemistry, signaling, pre-clinical and clinical activities on the role of nitric oxide donors/inhibitors used alone and in combination with other therapeutic agents for the treatment of a variety of diseases. This book examines various studies related to the application of novel therapeutic NO (donors/inhibitors) compounds in the treatment of various cancers. These studies have been shown to exert significant therapeutic activities against various cancers and various inflammatory diseases such as rheumatoid arthritis, Crohn’s disease, allergies, and asthma, where no current effective therapies exist. Pathologies based on functional and structural vascular alterations are also taken into consideration. Edited and written by internationally renowned experts in the field of novel therapeutics for cancer, this book is a valuable source for cancer researchers, medical scientists, clinicians, clinical pharmacologists, and graduate students.

  • Introductory Immunology

    Basic Concepts for Interdisciplinary Applications
    • 2nd Edition
    • Jeffrey K. Actor
    • English
    Introductory Immunology: Basic Concepts for Interdisciplinary Applications, Second Edition is a completely updated, revised and expanded resource on the immune system as a primary defense for the maintenance of health and homeostasis. The book highlights the components of the human immune system and how they work together to confer protection against pathogenic invaders. It also creates an understanding of the basis for clinical tests and immune therapeutics and their importance in identifying and treating disease states. This updated edition will strengthen the foundation required to understand the placement of immune function within clinical practice, thus allowing a basic platform to define therapeutic treatments.

  • Key Productivity and Performance Strategies to Advance Your Career

    • 1st Edition
    • Lesia L. Crumpton-Young
    • English
    Key Productivity and Performance Strategies to Advance Your STEM Career shares valuable knowledge and insights on best practices used by high performing individuals in the STEM fields to enhance their professional endeavors. The strategies contained in this book are based on Lesia L. Crumpton-Young's experience and expertise as a STEM professional and a certified Life and Career Coach. The book includes real-life examples from STEM professionals of career hurdles and efficient solutions to reaching your career goals. It covers effective goal setting, decision-making, and how best to overcome doubt and criticism, as well as practical advice on critical path analysis. Finally, the book includes a five-year career planning tool, along with additional problem statements and exercises, making it a valuable resource those involved in the STEM fields.

  • Anatomy and Histology of the Laboratory Rat in Toxicology and Biomedical Research

    • 1st Edition
    • Robert L. Maynard + 1 more
    • English
    Anatomy and Histology of the Laboratory Rat in Toxicology and Biomedical Research presents the detailed systematic anatomy of the rat, with a focus on toxicological needs. Most large works dealing with the laboratory rat provide a chapter on anatomy, but fall far short of the detailed account in this book which also focuses on the needs of toxicologists and others who use the rat as a laboratory animal. The book includes detailed guides on dissection methods and the location of specific tissues in specific organ systems. Crucially, the book includes classic illustrations from Miss H. G. Q. Rowett, along with new color photo-micrographs. Written by two of the top authors in their fields, this book can be used as a reference guide and teaching aid for students and researchers in toxicology. In addition, veterinary/medical students, researchers who utilize animals in biomedical research, and researchers in zoology, comparative anatomy, physiology and pharmacology will find this book to be a great resource.

  • Mosaic of Autoimmunity

    The Novel Factors of Autoimmune Diseases
    • 1st Edition
    • Carlo Perricone + 1 more
    • English
    The Mosaic of Autoimmunity: The Novel Factors of Autoimmune Diseases describes the multifactorial origin and diversity of expression of autoimmune diseases in humans. The term implies that different combinations of factors in autoimmunity produce varying and unique clinical pictures in a wide spectrum of autoimmune diseases. Most of the factors involved in autoimmunity can be categorized into four groups: genetic, immune defects, hormonal and environmental factors. In this book, the environmental factors are reviewed, including infectious agents, vaccines as triggers of autoimmunity, smoking and its relationship with rheumatoid arthritis, systemic lupus erythematosus, thyroid disease, multiple sclerosis and inflammatory bowel diseases. An entirely new syndrome, the autoimmune/inflammat... syndrome induced by adjuvants (ASIA), is also included, along with other diseases that are now recognized as having an autoimmune etiopathogenesis.

  • Biophysical Measurement in Experimental Social Science Research

    Theory and Practice
    • 1st Edition
    • Gigi Foster
    • English
    Biophysical Measurement in Experimental Social Science Research is an ideal primer for the experimental social scientist wishing to update their knowledge and skillset in the area of laboratory-based biophysical measurement. Many behavioral laboratories across the globe have acquired increasingly sophisticated biophysical measurement equipment, sometimes for particular research projects or for financial or institutional reasons. Yet the expertise required to use this technology and integrate the measures it can generate on human subjects into successful social science research endeavors is often scarce and concentrated amongst a small minority of researchers. This book aims to open the door to wider and more productive use of biophysical measurement in laboratory-based experimental social science research. Suitable for doctoral students through to established researchers, the volume presents examples of the successful integration of biophysical measures into analyses of human behavior, discussions of the academic and practical limitations of laboratory-based biophysical measurement, and hands-on guidance about how different biophysical measurement devices are used. A foreword and concluding chapters comprehensively synthesize and compare biophysical measurement options, address academic, ethical and practical matters, and address the broader historical and scientific context. Research chapters demonstrate the academic potential of biophysical measurement ranging fully across galvanic skin response, heart rate monitoring, eye tracking and direct neurological measurements. An extended Appendix showcases specific examples of device adoption in experimental social science lab settings.

  • Digital Twin Driven Smart Manufacturing

    • 1st Edition
    • Fei Tao + 2 more
    • English
    Digital Twin Driven Smart Manufacturing examines the background, latest research, and application models for digital twin technology, and shows how it can be central to a smart manufacturing process.The interest in digital twin in manufacturing is driven by a need for excellent product reliability, and an overall trend towards intelligent, and connected manufacturing systems. This book provides an ideal entry point to this subject for readers in industry and academia, as it answers the questions: (a) What is a digital twin? (b) How to construct a digital twin? (c) How to use a digital twin to improve manufacturing efficiency? (d) What are the essential activities in the implementation of a digital twin? (e) What are the most important obstacles to overcome for the successful deployment of a digital twin? (f) What are the relations between digital twin and New Technologies? (g) How to combine digital twin with the New Technologies to achieve high efficiency and smartness in manufacturing?This book focuses on these problems as it aims to help readers make the best use of digital twin technology towards smart manufacturing.

  • Artificial Neural Networks for Engineering Applications

    • 1st Edition
    • Alma Y Alanis + 2 more
    • English
    Artificial Neural Networks for Engineering Applications presents current trends for the solution of complex engineering problems that cannot be solved through conventional methods. The proposed methodologies can be applied to modeling, pattern recognition, classification, forecasting, estimation, and more. Readers will find different methodologies to solve various problems, including complex nonlinear systems, cellular computational networks, waste water treatment, attack detection on cyber-physical systems, control of UAVs, biomechanical and biomedical systems, time series forecasting, biofuels, and more. Besides the real-time implementations, the book contains all the theory required to use the proposed methodologies for different applications.

  • Computational Epigenetics and Diseases

    • 1st Edition
    • Volume 9
    • English
    Computational Epigenetics and Diseases, written by leading scientists in this evolving field, provides a comprehensive and cutting-edge knowledge of computational epigenetics in human diseases. In particular, the major computational tools, databases, and strategies for computational epigenetics analysis, for example, DNA methylation, histone modifications, microRNA, noncoding RNA, and ceRNA, are summarized, in the context of human diseases. This book discusses bioinformatics methods for epigenetic analysis specifically applied to human conditions such as aging, atherosclerosis, diabetes mellitus, schizophrenia, bipolar disorder, Alzheimer disease, Parkinson disease, liver and autoimmune disorders, and reproductive and respiratory diseases. Additionally, different organ cancers, such as breast, lung, and colon, are discussed. This book is a valuable source for graduate students and researchers in genetics and bioinformatics, and several biomedical field members interested in applying computational epigenetics in their research.

  • Science Teaching Essentials

    Short Guides to Good Practice
    • 1st Edition
    • Cynthia J. Brame
    • English
    Science Teaching Essentials: Short Guides to Good Practice serves as a reference manual for science faculty as they set up a new course, consider how to teach the course, figure out how to assess their students fairly and efficiently, and review and revise course materials. This book consists of a series of short chapters that instructors can use as resources to address common teaching problems and adopt evidence-based pedagogies. By providing individual chapters that can be used independently as needed, this book provides faculty with a just-in-time teaching resource they can use to draft a new syllabus. This is a must-have resource for science, health science and engineering faculty, as well as graduate students and post-docs preparing for future faculty careers.

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