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Academic Press

  • Intrinsically Disordered Proteins

    Dynamics, Binding, and Function
    • 1st Edition
    • Nicola Salvi
    • English
    Intrinsically Disordered Proteins: Dynamics, Binding, and Function thoroughly examines and ties together the fundamental biochemical functions of intrinsically disordered proteins (IDPs) and intrinsically disordered regions (IDRs), including signaling, binding, and regulation, with the methodology for study and the associated pathways for drug design and therapeutic intervention. The role of new mechanistic, computational, and experimental approaches in IDP study are explored in depth, with methods for the characterization of IDP dynamics; models, simulations, and mechanisms of IDP and IDR binding; and biological and medical implications of IDP dynamics prominently featured. Written and edited by leading scientists in the field, this book explores groundbreaking areas such as ensemble descriptions of IDPs and IDRs, single-molecule studies of IDPs and IDRs, IDPs and IDRs in membraneless organelles, and molecular mechanisms of fibrillation of IDPs. Intrinsically Disordered Proteins provides students and researchers in biochemistry, molecular biology, and applied microbiology with a comprehensive and updated discussion of the complex dynamics of IDPs and IDRs.
  • Mitochondrial Neuropathies

    • 1st Edition
    • Volume 145
    • English
    Mitochondrial Neuropathies, Volume 146, brings together experts in a range of diseases that damage the nervous system to present the role of mitochondrial dysfunction in their particular field, with this new release focusing on Mitochondrial dysfunction in Alzheimer's Disease, HIV and the mitochondrial: immune interface in the CNS, The Impact of mitochondrial damage in HIV-induced peripheral neuropathy, Mitochondrial dysfunction and the pathogenesis of chemotherapy-induced peripheral neuropathy, Disorders of mitochondrial biogenesis in peripheral neuropathy, Mitochondrial dysfunction and the pathogenesis of diabetic neuropathy, Manipulating mitochondria to treat peripheral neuropathy, and DCA therapy - the yin and yang of mitochondrial activation.
  • Internet of Things in Biomedical Engineering

    • 1st Edition
    • Valentina Emilia Balas + 4 more
    • English
    Internet of Things in Biomedical Engineering presents the most current research in Internet of Things (IoT) applications for clinical patient monitoring and treatment. The book takes a systems-level approach for both human-factors and the technical aspects of networking, databases and privacy. Sections delve into the latest advances and cutting-edge technologies, starting with an overview of the Internet of Things and biomedical engineering, as well as a focus on ‘daily life.’ Contributors from various experts then discuss ‘computer assisted anthropology,’ CLOUDFALL, and image guided surgery, as well as bio-informatics and data mining. This comprehensive coverage of the industry and technology is a perfect resource for students and researchers interested in the topic.
  • Numerical PDE Analysis of Retinal Neovascularization

    Mathematical Model Computer Implementation in R
    • 1st Edition
    • William E. Schiesser
    • English
    Numerical PDE Analysis of Retinal Neovascularization Mathematical Model Computer Implementation in R provides a methodology for the analysis of neovascularization (formation of blood capillaries) in the retina. It describes the starting point—a system of three partial differential equations (PDEs)—that define the evolution of (1) capillary tip density, (2) blood capillary density and (3) concentration of vascular endothelial growth factor (VEGF) in the retina as a function of space (distance along the retina), x, and time, t, the three PDE dependent variables for (1), (2) and (3), and designated as u1(x, t), u2(x, t), u3(x, t), amongst other topics.
  • 3D Data Acquisition for Bioarchaeology, Forensic Anthropology, and Archaeology

    • 1st Edition
    • Noriko Seguchi + 1 more
    • English
    3D Data Acquisition for Bioarchaeology, Forensic Anthropology, and Archaeology serves as a handbook for the collection and processing of 3-D scanned data and as a tool for scholars interested in pursuing research projects with 3-D models. The book's chapters enhance the reader’s understanding of the technology by covering virtual model processing protocols, alignment methods, actual data acquisition techniques, basic technological protocols, and considerations of variation in research design associated with biological anthropology and archaeology.
  • Biopolymer Nanostructures for Food Encapsulation Purposes

    Volume 1 in the Nanoencapsulation in the Food Industry series
    • 1st Edition
    • Volume 1
    • Seid Mahdi Jafari
    • English
    Biopolymer Nanostructures for Food Encapsulation Purposes, a volume in the Nanoencapsulation in the Food Industry series, guides readers on how to fabricate and apply nanostructures from different proteins, carbohydrates and chemical sources for food encapsulation purposes. This book covers recent and applied research in all disciplines of bioactive and nutrient delivery. Chapters emphasize original results relating to experimental, theoretical, formulations and/or applications of nano-structured biopolymers.
  • Equipment Qualification in the Pharmaceutical Industry

    • 1st Edition
    • Steven Ostrove
    • English
    Equipment Qualification in the Pharmaceutical Industry provides guidance and basic information for the preparation of a quality qualification program. It has been noted that there is a general lack of understanding in the industry, especially for those new to the industry, as to what constitutes a compliant qualification program. Even experienced professionals have felt a lack of security in reaching a compliant state. This book outlines a guideline for the preparation and execution of qualification protocols including the installation (IQ), operational (OQ), and performance (PQ) protocols. It discusses the importance of related qualification programs (e.g., quality systems, commissioning, computer system, and cleaning) and how to incorporate them into a fully compliant qualification program. Furthermore, it provides matrices of what could be included in each type of protocol for major types of process equipment. While primarily for people entering the pharmaceutical industry, those established in the field will benefit from the multiple examples and matrices as well as integration of related systems. Equipment Qualification in the Pharmaceutical Industry provides students and pharmaceutical scientists a guideline for the preparation and execution of qualification (installation, operational, and performance) protocols.
  • Immunotherapy of Cancer

    • 1st Edition
    • Volume 143
    • English
    Immunotherapy of Cancer, Volume 143, the latest release in the Advances in Cancer Research series, provides invaluable information on the exciting and fast-moving field of cancer research. Contributions from leading experts in the field make this a must have update on the topic.
  • Development of the Nervous System

    • 4th Edition
    • Dan H. Sanes + 3 more
    • English
    Development of the Nervous System, Fourth Edition provides an informative and up-to-date account of our present understanding of the basic principles of neural development as exemplified by key experiments and observations from past and recent times. This book reflects the advances made over the last few years, demonstrating their promise for both therapy and molecular understanding of one of the most complex processes in animal development. This information is critical for neuroscientists, developmental biologists, educators, and students at various stages of their career, providing a clear presentation of the frontiers of this exciting and medically important area of developmental biology. The book includes a basic introduction to the relevant aspects of neural development, covering all the major topics that form the basis of a comprehensive, advanced undergraduate and graduate curriculum, including the patterning and growth of the nervous system, neuronal determination, axonal navigation and targeting, neuron survival and death, synapse formation and plasticity.
  • Dietary Fiber: Properties, Recovery, and Applications

    • 1st Edition
    • Charis M. Galanakis
    • English
    Dietary Fiber: Properties, Recovery and Applications explores the properties and health effects of dietary fiber, along with new trends in recovery procedures and applications. The book covers the most trending topics of dietary fiber applications, emphasizing polyphenol properties, bioavailability and metabolomics, target sources, recovery and emerging technologies, technological aspects, stability during processing, and applications in the food, beverage and nutraceutical sectors. Written by a team of experts in the field of dietary fiber, this book is ideal for chemists, food scientists, technologists, new product developers and academics.