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Elsevier

Academic Press

  • Difficult to Diagnose Rare Diffuse Lung Disease

    • 1st Edition
    • Alexander V. Averyanov
    • English
    Difficult to Diagnose Rare Diffuse Lung Disease presents the theoretical basis and practical aspects of differential diagnoses of rare lung diseases with the use of new method of probe-based confocal laser endomicroscopy (alveoscopy) of the distal respiratory region. Each chapter describes signs and symptoms of the disease and its typical and atypical manifestations. The book contains full color illustrations, including high-resolution histological microphotographs, CT-scans and confocal laser endomicroscopy images. In combination, these elements make this book an invaluable reference and guide for pulmonary researchers, pulmonologists, radiologists, and pathologists who wish to broaden their spectrum of knowledge in rare lung diseases.

  • Physics of Biological Action and Perception

    • 1st Edition
    • Mark L. Latash
    • English
    Physics of Biological Action and Perception helps researchers interested in exploring biological motor control from a physics or alternative viewpoint perspective. The book introduces the idea of parametric control as a distinguishing feature of living systems. Sections cover how the CNS creates stable percepts based on fuzzy and continuously changing signals from numerous receptors and the variable processes related to ongoing actions. The author also develops the idea of control with referent coordinates to stability of salient variables in fields typically united under the label of "cognition." Examples of this include communication (how the gist of a message is preserved despite variability of phrases), thought processes (how one can solve a mental problem via different logical routes), and playing chess (how one selects an optimal move given a position on the board). The book is written for researchers, instructors, clinicians and other professionals in all the fields related to biological movement and perception.

  • Nanomycotoxicology

    Treating Mycotoxins in the Nano Way
    • 1st Edition
    • Mahendra Rai + 1 more
    • English
    Nanomycotoxicology: Treating Mycotoxins in Nanoway discusses the role of nanotechnology in the detection, toxicity and management of different types of mycotoxins. Sections cover the topic of nanomycotoxicology, the application of nanotechnology for quicker, more cost-effective and precise diagnostic procedures of mycotoxins and toxicogenic fungi, and the application of nanotechnology for the management of mycotoxigenic fungi. New topics, such as the application of nanotechnology in disease management, disease forecasting, and disease resistance, mycotoxin detection, and nanodiagnostic and molecular techniques are also presented. With chapter contributions from an international group of experts, this book presents an interdisciplinary reference for scientists and researchers working in mycotoxicology, nanotechnology, mycology, plant science, and food safety. In addition, it will be a useful tool for industrial scientists investigating technologies to update their nanotoxicology and nanosafety knowledge.

  • How to Integrate Quality by Efficient Design (QbED) in Product Development

    • 1st Edition
    • Bhavishya Mittal
    • English
    The development of a robust drug product requires juggling many competing priorities such as overcoming scientific challenges, following regulatory requirements, and managing business-related concerns. Unfortunately, despite large resources spent on R&D, multifactor productivity of pharmaceuticals is on the decline for several years now. Because of this business reality, pharmaceutical companies have seen a notable change in the traditional operating model and footprint over the past couple of decades. Outsourcing, in particular, has emerged as a successful business model for many pharmaceutical companies looking for ways to strategically increase their R&D capabilities and to augment their in-house resources. How to Integrate Quality by Efficient Design (QbED) in Product Development bridges the gap between theory and practice when it comes to strategic decision-making in a pharmaceutical research scenario. This book will introduce the concept of QbED and focus on various aspects such as patient-centric product designs, platform-based manufacturing technologies, business acuity, and regulatory strategies to balance the challenges in outsourcing with the need for strategic and statistically sound experiments rooted in good science. Detailed discussions will cover pharmaceutical business models, regulatory approval process, quality by design (QbD), business analytics, and manufacturing excellence specifically for small molecules and solid oral dosage forms. With the addition of case studies, flowcharts, diagrams, and data visualizations, How to Integrate Quality by Efficient Design (QbED) in Product Development will be a practical reference to help professionals working in the area of pharmaceutical drug development, strategy, and outsourcing management.

  • Advanced Low-Cost Separation Techniques in Interface Science

    • 1st Edition
    • Volume 30
    • George Z. Kyzas + 1 more
    • English
    Advanced Low-Cost Separation Techniques in Interface Science, Volume 30 helps scientists and researchers in academia and industry gain expert knowledge on how to use separation techniques at minimal cost and energy usage. It handles a broad range of highly relevant topics, including modern flotation techniques, low-cost materials in liquid-and gas-phase adsorption, new trends in molecular imprinting, graphenes in separation, nanobubbles and biopolymers in interface science, the reuse of biomaterials, green techniques for wastewaters, and modeling in environmental interfaces. The book shows that these techniques can be both attractive for both research and industrial purposes. It is intended for chemical engineers working in wastewater treatment industries, membrane industries, pharmaceutical industries, textile or tanneries industries, hybrid-topic industries and energy industries.

  • Cellular Nutrient Utilization and Cancer

    • 1st Edition
    • Volume 347
    • English
    Cellular Nutrient Utilization and Cancer, Volume 347 in the International Review of Cell and Molecular Biology (IRCMB) series maintains a high standard by publishing invited articles on timely topics that are authored by prominent cell and molecular biologists. Sections in this new release include Sulfur metabolism and cancer, The interplay of genetic drivers of cancer and cellular nutrients to support oncogenesis, The diet’s impact on nutrient availability for cancer cells, Nutrients as determinants of redox balance in cancer, The role of dietary lipids in colon cancer pathogenesis, The influence of diet on nutrient utilization by cancer cells and immune-surveillance, and more.

  • Patent Foramen Ovale Closure for Stroke, Myocardial Infarction, Peripheral Embolism, Migraine, and Hypoxemia

    • 1st Edition
    • M. Khalid Mojadidi + 2 more
    • English
    Patent Foramen Ovale (PFO) Closure for Stroke, Myocardial Infarction, Peripheral Embolism, Migraine, and Hypoxemia is a complete reference covering the association between PFO and numerous medical conditions. It provides a background on the topic including embryology, anatomy, and physiology. This book fully examines the diagnosis and imaging assessment of PFO and discusses the data linking PFO to various clinical pathologies. It details technical aspects of PFO closure and includes perspectives on future outlooks and where the field is headed in terms of device closure indications. This is a complete reference book for cardiologists, interventional cardiologists, neurologists, pulmonologists, general practitioners, medical professionals, and researchers who are interested in PFO-associated pathologies, technical aspects, safety, and future outlooks of PFO device closure.

  • Molecular Nutrition

    Vitamins
    • 1st Edition
    • Vinood B. Patel
    • English
    Molecular Nutrition: Vitamins presents the nutritional and molecular aspects of vitamins with a specific focus on vitamins A, B1 (thiamine), B2 (riboflavin), B# (niacin), B5 (pantothenic acid), B6, (pyridoxine), B7 (biotin), B9 (folate), B12 (colbamin), C, D, E, and K. As part of the Molecular Nutrition series, this book discusses introductory aspects and general coverage of vitamins and nutrition, the molecular biology of the cell, including signaling, transporters, oxidative stress, receptors, uptake, immunity, proliferation, endoplasmic reticulum, differentiation, carcinogenesis and apoptosis. Final sections cover genetic machinery and its function, transcriptional processes, homeostasis genes, cancer, gene expression, mutations, and more. Emerging fields of molecular biology and important discoveries related to diet and nutritional health are also covered, rounding out the book.

  • DHM and Posturography

    • 1st Edition
    • Sofia Scataglini + 1 more
    • English
    DHM and Posturography explores the body of knowledge and state-of-the-art in digital human modeling, along with its application in ergonomics and posturography. The book provides an industry first introductory and practitioner focused overview of human simulation tools, with detailed chapters describing elements of posture, postural interactions, and fields of application. Thus, DHM tools and a specific scientific/practical problem – the study of posture – are linked in a coherent framework. In addition, sections show how DHM interfaces with the most common physical devices for posture analysis. Case studies provide the applied knowledge necessary for practitioners to make informed decisions. Digital Human Modelling is the science of representing humans with their physical properties, characteristics and behaviors in computerized, virtual models. These models can be used standalone, or integrated with other computerized object design systems, to design or study designs, workplaces or products in their relationship with humans.

  • Principles of Bone Biology

    • 4th Edition
    • John P. Bilezikian + 3 more
    • English
    Preface from the first edition (1996): "The world of modern science is undergoing a number of spectacular events that are redefining our understanding of ourselves. As with any revolution, we should take stock of where we have been, where we are, and where we are going. Our special world of bone biology is participating in and taking advantage of the larger global revolution in modern science… we assembled experts from all over the world and asked them to focus on the current state of knowledge and the prospects for new knowledge in their area of expertise. To this end,　Principles of Bone Biology　was conceived." - John P. Bilezikian, Lawrence G. Raisz, Gideon A. Rodan Praise for the previous edition: "Students, teachers, and practitioners will benefit from reading it, and investigators will use it as a reference work; it will certainly be consulted frequently." --The New England Journal of Medicine For over two decades, "Big Gray" has been the go-to repository of knowledge in the disciplines related to bone and mineral metabolism. The fourth edition is a must-have for students new to the field; young investigators at the graduate or postgraduate level beginning their research careers; established scientists who need to keep up with the changing nature of the field, looking to enrich their own research programs, or who are changing their career direction; clinicians who want ready access to up-to-date relevant basic science. This new edition builds on the successful formula from previous editions, taking the reader from the basic elements of fundamental research to the most sophisticated concepts in therapeutics. Principles of Bone Biology, Fourth Edition provides the most comprehensive, authoritative reference on the study of bone biology and related diseases. Bone research continues to generate enormous attention, due to the broad public health implications of osteoporosis and related bone disorders. This classic, fully updated, two volume reference is designed for anyone involved in the study of bone biology.

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