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Academic Press

  • Ion Channels and Calcium Signaling in the Microcirculation

    • 1st Edition
    • Volume 85
    • English
    Ion Channels and Calcium Signaling in the Microcirculation, Volume 85, the latest release in the Current Topics in Membranes series, highlights the latest advances in the expression and function of ion channels and calcium signaling in vascular smooth muscle and endothelial cells in resistance arteries, arterioles and capillaries, critical components of microcirculation, the business end of the cardiovascular system. Leading experts have contributed chapters, including Smooth muscle ion channels and calcium signaling in the regulation of striated muscle arteriolar tone; Endothelial KIR channels as a key component of shear stress-induced mechanotransduction; Endothelial TRPV4 channels and vasodilator reactivity, and much more. Additional sections cover cerebral capillary endothelial TRPA channels and the regulation of blood flow; Endothelial mineralocorticoid receptors and the regulation of TRPV4 function in cerebral parenchymal arterioles in hypertension; Subcellular calcium signaling and myogenic tone development in the retinal microcirculation; Microvascular KIR channels: Basis, properties and regulation by lipid and hemodynamic forces, Ion channels and calcium signaling in capillary endothelial cells; Ion channels and calcium signaling in bladder arterioles and resistance arteries, and Myoendothelial feedback and endothelial IKCa and sKCa channels.

  • Digital Twin Driven Smart Design

    • 1st Edition
    • Fei Tao + 3 more
    • English
    Digital Twin Driven Smart Design draws on the latest industry practice and research to establish a basis for the implementation of digital twin technology in product design. Coverage of relevant design theory and methodology is followed by detailed discussions of key enabling technologies that are supported by cutting-edge case studies of implementation. This groundbreaking book explores how digital twin technology can bring improvements to different kinds of product design process, including functional, lean and green. Drawing on the work of researchers at the forefront of this technology, this book is the ideal guide for anyone interested in digital manufacturing or computer-aided design.

  • Advances in Applied Microbiology

    • 1st Edition
    • Volume 110
    • Geoffrey M. Gadd + 1 more
    • English
    Advances in Applied Microbiology, Volume 110, the latest release in this renowned series that provides a comprehensive and authoritative review in microbiology, includes updated chapters on Multi-species biofilms for resource recovery from wastewater, Chemical imaging of biofilms with luminescent sensors, Advances in yeast fermentation biotechnology, Bacterial evasion of host defense systems, A genomic analysis on stress-responses in C. glabrata and their relevance in pathogenesis and drug resistance, and more.

  • Psychostimulants

    • 1st Edition
    • Volume 2
    • George F. Koob + 3 more
    • English
    A current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction are detailed in our Neurobiology of Addiction series, each volume addressing a specific area of addiction. Psychostimulants, Volume 2 in the series, explores the molecular and cellular systems in the brain responsible for psychostimulant addiction, including both direct/indirect sympathomimetics and nonsympathomimetics. This volume introduces the readers to the history of psychostimulant use. The authors clearly differentiate the neurobiological effects into three distinct stages of the addiction cycle: binge/intoxication, withdrawal/negative affect, and preoccupation/antici...

  • Rabies

    Scientific Basis of the Disease and Its Management
    • 4th Edition
    • Anthony R. Fooks + 1 more
    • English
    Rabies: Basis of the Disease and Its Management, Fourth Edition is an authoritative reference on the current status of rabies, including the virological, clinical, and public health aspects and management recommendations. Rabies remains one of the most important global public health problems worldwide. Although many important developments have been made over the past century to combat this disease, rabies has become a re-emergent infection in the resource-constrained countries. The Fourth Edition updates this classic reference with comprehensive coverage of the molecular virology, pathogenesis, immunology, vaccines, public health aspects, and epidemiology of rabies and is completely revised, with new chapters that will cover historical developments in rabies intervention strategies, the evolution of rabies virus, modeling rabies control, and on the strategy for rabies elimination. Rabies, Fourth Edition, provides physicians, veterinarians, public health advisors, epidemiologists, and research scientists with a single source for authoritative and up-to-date information on the diagnosis, treatment, control, and prevention of this fatal infectious virus.

  • Theories of Adolescent Development

    • 1st Edition
    • Barbara M. Newman + 1 more
    • English
    Adolescence is both universal and culturally constructed, resulting in diverse views about its defining characteristics. Theories of Adolescent Development brings together many theories surrounding this life stage in one comprehensive reference. It begins with an introduction to the nature of theory in the field of adolescence including an analysis of why there are so many theories in this field. The theory chapters are grouped into three sections: biological systems, psychological systems, and societal systems. Each chapter considers a family of theories including scope, assumptions, key concepts, contributions to the study of adolescence, approaches to measurement, applications, and a discussion of strengths and limitations of this family. A concluding chapter offers an integrative analysis, identifying five assumptions drawn from the theories that are essential guides for future research and application. Three questions provide a focus for comparison and contrast: How do the theories characterize the time and timing of adolescence? What do the theories emphasize as domains that are unfolding in movement toward maturity? Building on the perspective of Positive Youth Development, how do the theories differ in their views of developmental resources and conditions that may undermine development in adolescence?

  • Nanomedicine for Ischemic Cardiomyopathy

    Progress, Opportunities, and Challenges
    • 1st Edition
    • Morteza Mahmoudi
    • English
    Nanomedicine for Ischemic Cardiomyopathy: Progress, Opportunities, and Challenges provides an overview on the recent advances in diagnostic and treatment of ischemic cardiomyopathy diseases including myocardial infarction. Shortcomings of the current methods and how nanomedicine can address those obstacles in the field are discussed including the limitations of newly developed cell therapy approaches to clinical translation and how nanomedicine may overcome crucial issues and facilitate the successful and efficient clinical translation of cell therapy. Biomolecular therapy is also explored as another powerful approach for regeneration of heart tissue including available methods and systematic delivery of biomolecules using nanocarriers to the injured part of myocardium through active targeting. Finally, coverage of major tissue engineering advances for myocardial regeneration, including use of epicardial nanostructured patches for regeneration of injured epicardium and the highly conductive patches for enhancing cross talks between the cardiomyocytes, is explored. This concise, yet rigorous coverage, of the field of cardiac nanotechnology outlines the innovative and necessary role of nanomedicine in regenerative medicine for cardiac repair allowing researchers, clinicians, and nanotechnologists to examine the strengths and limitations of current findings and predict future trends to advance the applications of nanotechnology in cardiovascular biomedical research.

  • Risky Decision Making in Psychological Disorders

    • 1st Edition
    • Melissa Buelow
    • English
    Risky Decision Making in Psychological Disorders provides readers with a detailed examination of how risky decision making is affected by a wide array of individual psychological disorders. The book starts by providing important background information on the construct of risky decision making, the assessment of risky decision making, and the neuroscience behind such decision making. The Iowa Gambling Task, Balloon Analogue Risk Task, and other behavioral measures are covered, as are topics such as test reliability and the pros and cons of utilizing tasks that have strong practice effects. The book then moves into how risky decision making is affected by specific psychological disorders, such as addictive behaviors, anxiety disorders, mood disorders, schizophrenia, sleep disorders, eating disorders, and more.

  • Cell Death Regulation in Health and Disease - Part C

    • 1st Edition
    • Volume 353
    • English
    Cell Death Regulation in Health and Disease - Part C, Volume 353 in the International Review of Cell and Molecular Biology series, reviews and details current advances in cell and molecular biology. The IRCMB series maintains the highest standard by publishing timely topics authored by prominent cell and molecular biologists, with this release covering Developmental and seasonal regulation of neural cell death in birds, Post-translational modifications in cell death regulation, The role of cell death in tissue regeneration and fibrosis, Crosstalk between the apoptosis and autophagy signaling pathways, IP3 receptor signal integration in cell death and survival decisions, and more.

  • Exploring Engineering

    An Introduction to Engineering and Design
    • 5th Edition
    • Robert Balmer + 1 more
    • English
    Engineers solve problems and work on emerging challenges in a wide range of areas important to improving quality of life; areas like sustainable energy, access to clean water, and improved communications and health care technologies. Kosky et al’s Exploring Engineering explores the world of engineering by introducing the reader to what engineers do, the fundamental principles that form the basis of their work, and how they apply that knowledge within a structured design process. The three-part organization of the text reinforces these areas, making this an ideal introduction for anyone interested in exploring the various fields of engineering and learning how engineers work to solve problems. The 5th edition has been revised to better reflect the knowledge base of incoming freshmen, and new content has been added for several new and emerging engineering disciplines, such as environmental engineering, cybersecurity, additive manufacturing, and mechatronics, as well as new design projects

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