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    • Vasopressin

      • 1st Edition
      • Volume 113
      • March 3, 2020
      • Gerald Litwack
      • English
      • Hardback
        9 7 8 0 1 2 8 2 0 8 1 6 8
      • eBook
        9 7 8 0 1 2 8 2 0 8 1 7 5
      Vasopressin, Volume 113 in the Vitamins and Hormones series, highlights new advances in the field, with this new volume presenting updates on timely topics, including Diabetes Insipidus in Pregnancy, Vasopressin Inactivation: Role of Insulin-Regulated Aminopeptidase, Vasotocin and the Origins of the Vasopressin/Oxytocin Receptor Gene Family, Vasopressin V2 Receptor Ligand Recognition, Development and Therapeutic Potential of Vasopressin Synthetic Analog [V4Q5]dDAVP as a Novel Anticancer Agent, Cellular Junctions and Vasopressin, Vasopressin Actions in the Kidney Renin Angiotensin System and its Role in Hypertension and Renal Disease, Oxytocin/Vasopressin... Neuropeptide Signaling in Insects, and much more.

    • International Review of Cell and Molecular Biology

      • 1st Edition
      • Volume 350
      • March 2, 2020
      • English
      • Hardback
        9 7 8 0 1 2 8 1 9 7 4 4 8
      • eBook
        9 7 8 0 1 2 8 1 9 7 4 6 2
      International Review of Cell and Molecular Biology, Volume 350, covers all aspects of endoplasmic reticulum (ER) biology. With its multiple cellular functions, including ion storage as well protein folding, trafficking and secretion, the regulation of homeostasis within the ER is crucial to organismal health. New sections in this updated volume include DAMP emission upon ER stress, Protein misfolding disordersm Type I interferon response and ER stress, ER and autophagosome biogenesis, Mitochondria-associa... membranes, ER calcium signaling in excitable cells, and ER in viral infections.

    • Mechanical Vibrations and Condition Monitoring

      • 1st Edition
      • March 1, 2020
      • Juan Carlos A. Jauregui Correa + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 9 7 9 6 7
      • eBook
        9 7 8 0 1 2 8 2 0 3 9 0 3
      Mechanical Vibrations and Condition Monitoring presents a collection of data and insights on the study of mechanical vibrations for the predictive maintenance of machinery. Seven chapters cover the foundations of mechanical vibrations, spectrum analysis, instruments, causes and effects of vibration, alignment and balancing methods, practical cases, and guidelines for the implementation of a predictive maintenance program. Readers will be able to use the book to make predictive maintenance decisions based on vibration analysis. This title will be useful to senior engineers and technicians looking for practical solutions to predictive maintenance problems. However, the book will also be useful to technicians looking to ground maintenance observations and decisions in the vibratory behavior of machine components.

    • Adolescent Addiction

      • 2nd Edition
      • March 1, 2020
      • Cecilia A. Essau + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 8 6 2 6 8
      • eBook
        9 7 8 0 1 2 8 1 9 3 0 0 6
      Adolescent Addiction, Second Edition, offers researchers and clinicians a single-volume resource on the nature, extent and treatment of addictive problems in adolescents. The book is divided into three main parts. Part one addresses the foundations of addictive problems, including developmental, social, and neurobiologicl factors. Part two addresses common addictions among adolescents. New chapters include e-cigarette, smartphone, social networking, and exercise addiction. Part three discusses challenges and recommendations for future research in adolescent addiction. All chapters in part two follow a similar format to introduction and clinical characteristics, screening and clinical assessment methods, epidemiology, cormorbidity, course and outcome, protective and risk factors, evidence-based clinical strategies for prevention and treatment, and a concise summary of key clinical points.

    • Acoustic Signals and Hearing

      • 1st Edition
      • February 29, 2020
      • Mikio Tohyama
      • English
      • Paperback
        9 7 8 0 1 2 8 1 6 3 9 1 7
      • eBook
        9 7 8 0 1 2 8 1 6 6 1 1 6
      Understanding acoustics – the science of sound -- is essential for audio and communications engineers working in media technology. It is also extremely important for engineers to understand what allows a sound to be heard in the way it is, what makes speech intelligible, and how a particular sound is recognized within a multitude of sounds. Acoustic Signals and Hearing: A Time-Envelope and Phase Spectral Approach is unique in presenting the principles of sound and sound fields from the perspective of hearing, particularly through the use of speech and musical sounds. Acoustic Signals and Hearing: A Time-Envelope and Phase Spectral Approach is an ideal resource for researchers and acoustic engineers working in today’s environment of media technology, and graduate students studying acoustics, audio engineering, and signal processing.

    • Secondary Findings in Genomic Research

      • 1st Edition
      • February 29, 2020
      • English
      • Paperback
        9 7 8 0 1 2 8 1 6 5 4 9 2
      • eBook
        9 7 8 0 1 2 8 1 6 7 4 8 9
      Secondary Findings in Genomic Research offers a single, highly accessible resource on interpreting, managing and disclosing secondary findings in genomic research. With chapters written by experts in the field, this book is the first to concisely explain the ethical and practical issues raised by secondary genomics findings for a multi and interdisciplinary audience of genomic researchers, translational scientists, clinicians, medical students, genetic counselors, ethicists, legal experts and law students, public policy specialists and regulators. Contributors from Europe, North America, and Asia effectively synthesize perspectives from a spectrum of different scientific, societal, and global contexts, and offer pragmatic approaches to a range of topics, including oversight, governance and policy surrounding secondary genomic results, criteria for identifying results for return, communication and consent, stakeholders’ attitudes and perspectives, disclosing results, and clinical, patient-centered protocols.

    • Chickpea: Crop Wild Relatives for Enhancing Genetic Gains

      • 1st Edition
      • February 29, 2020
      • Mohar Singh
      • English
      • Paperback
        9 7 8 0 1 2 8 1 8 2 9 9 4
      • eBook
        9 7 8 0 1 2 8 1 8 3 0 0 7
      Chickpea: Crop Wild Relatives for Enhancing Genetic Gains explores aspects related to critical analysis on factors responsible for narrow genetic base of chickpea productions including domestication bottleneck, the level of diversity present in different cultivated and wild species, the uniqueness and usefulness of potential gene sources available and maintained in production systems across the globe, the level of genetic erosion both at landrace and species level over time and space etc. Despite considerable international investment in conventional breeding, production of chickpea has not yet been significantly improved beyond that achieved through its normal single domestication event and high self-pollination rate. Total annual pulse production of ~12 million tons (FAO 2016) is far below actual potential. Susceptibility to both biotic and abiotic stresses have created a production level bottleneck whose solution possibly lies in the use of crop wild relatives and other genetic traits cultivated by tailoring novel germplasm. Presenting options for widening the genetic base of chickpea cultivars by introgression of diverse genes available in distantly related wild Cicer taxa, thus expanding the genetic base and maximize genetic gains from the selection, it is necessary to accumulate other complimentary alleles from CWRs. This review will focus on present status of gene pool and species distribution, germplasm conservation, characterization and evaluation, problems associated with crop production, sources of target traits available in wild species, status of trait introgression in synthesizing new gene pool of chickpea along with progress made in chickpea genomics. An edited book with contributions from leading scientists, this information will guide and inform chickpea breeders, PGR researchers and crop biologists across the world.

    • Giardia and Giardiasis - Part B

      • 1st Edition
      • Volume 107
      • February 28, 2020
      • English
      • Hardback
        9 7 8 0 1 2 8 2 0 4 7 5 7
      • eBook
        9 7 8 0 1 2 8 2 2 1 9 7 6
      Giardia and Giardiasis Volume 107-Part B, in the Advances in Parasitology series, is dedicated to aspects of cytoskeletal structure of this parasite with an emphasis on insights of new components and their function in trophozoites. Further, microtubule function and its critical involvement in motility, attachment, mitosis and cell division as well as in transitions between developmental stages are reviewed. Also a comprehensive revision in the progress of tools to explore and understand the functional biology of Giardia, its coding and non-coding genes, features and cellular and molecular biology is contained in this volume. Additionally, an exciting perspective on the interactions between Giardia and intestinal epithelial cell by reviewing transcriptomic and proteomic investigations is included along with a state-of-the art of the understanding pathophysiology of giardiasis and of how Giardia can cause post-infectious and extra-intestinal complications. A complete review of current knowledge including commonly prescribed drugs, causes of therapeutic fails, drug resistance mechanisms, strategies for the discovery of new agents for alternative drug therapies is covered.

    • Bioactive Materials for Bone Regeneration

      • 1st Edition
      • February 28, 2020
      • Jiang Chang + 2 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 3 5 0 3 7
      • eBook
        9 7 8 0 1 2 8 1 3 5 0 4 4
      Bioactive Materials for Bone Regeneration summarizes research advances on the topic, including sections on the characteristics of biomaterial-induced microenvironments, interactions of bioactive materials with stem cells and tissues, and the immunomodulatory microenvironment induced by biomaterials and its effects on osteogenesis. As the regeneration of large-size bone tissue defects represents a significant clinical challenge, this book demonstrates how new biomaterials with specific chemical and physical characteristics may interact with the host and create a unique micro-environment that actively facilitates stem cell differentiation along a specific lineage, thus stimulating tissue regeneration.

    • Tumor Immunology and Immunotherapy - Integrated Methods Part A

      • 1st Edition
      • Volume 635
      • February 28, 2020
      • English
      • Hardback
        9 7 8 0 1 2 8 1 8 6 7 7 0
      • eBook
        9 7 8 0 1 2 8 1 8 8 7 5 0
      Tumor Immunology and Immunotherapy Integrated Methods - Part A, Volume 635 in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Specific chapters to this release include Deconvolution of the immunological contexture of mouse tumors with multiplexed immunohistochemistry... High-dimensional multiplexed immunohistochemical characterization of immune contexture in human cancers, Multiplex assay by IHC for melanoma tumor microenvironment evaluation, Characterization of the tumor immune microenvironment by multispectral image analysis of multiplex immunofluorescence images, Phenotyping of immune cells in situ using multispectral imaging quantification, and much more.

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