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Academic Press

    • Drug Resistance in Colorectal Cancer: Molecular Mechanisms and Therapeutic Strategies

      • 1st Edition
      • Volume 8
      • May 24, 2020
      • Chi Hin Cho + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 8 1 9 9 3 7 4
      • eBook
        9 7 8 0 1 2 8 1 9 9 3 8 1
      Drug Resistance in Colorectal Cancer: Molecular Mechanisms and Therapeutic Strategies, Volume Eight, summarizes the molecular mechanisms of drug resistance in colorectal cancer, along with the most up-to-date therapeutic strategies available. The book discusses reasons why colorectal tumors become refractory during the progression of the disease, but also explains how drug resistance occurs during chemotherapy. In addition, users will find the current therapeutic strategies used by clinicians in their practice in treating colorectal cancer. The combination of conventional anticancer drugs with chemotherapy-sensiti... agents plays a pivotal role in improving the outcome of colorectal cancer patients, in particular those with drug-resistant cancer cells. From a clinical point-of-view, the content of this book provides clinicians with updated therapeutic strategies for a better choice of drugs for drug-resistant colorectal cancer patients. It will be a valuable source for cancer researchers, oncologists and several members of biomedical field who are dedicated to better treat patients with colorectal cancer.

    • Digital Twin Development and Deployment on the Cloud

      • 1st Edition
      • May 24, 2020
      • Nassim Khaled + 2 more
      • English
      • Paperback
        9 7 8 0 1 2 8 2 1 6 3 1 6
      • eBook
        9 7 8 0 1 2 8 2 1 6 4 6 0
      Digital Twin Development and Deployment in the Cloud: Developing Cloud-Friendly Dynamic Models Using Simulink®/SimscapeTM and Amazon AWS promotes a physics-based approach to the field of digital twins. Through the use of multiphysics models running in the cloud, significant improvement to the diagnostics and prognostic of systems can be attained. The book draws a clear definition of digital twins, helping business leaders clearly identify the value it brings. In addition, it outlines the key elements needed for deployment, including the hardware and software tools needed. Special attention is paid to the process of developing and deploying the multi-physics models of the digital twins.

    • Aging

      • 2nd Edition
      • May 24, 2020
      • Victor R. Preedy + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 8 6 9 8 5
      • eBook
        9 7 8 0 1 2 8 1 8 8 1 1 8
      Aging: Oxidative Stress and Dietary Antioxidants, Second Edition, bridges the trans-disciplinary divide and covers the science of oxidative stress in aging and the therapeutic use of natural antioxidants in the food matrix in a single volume. The second edition covers new trials and investigations used to determine the comprehensive properties of antioxidants, food items and extracts, as well as any adverse properties they may have. It has been updated to include new clinical human trials and a new section dedicated to animal models of aging. Throughtout the book the processes within the science of oxidative stress are described in concert with other processes, such as apoptosis, cell signaling, and receptor mediated responses. This approach recognizes that diseases are often multifactorial, and oxidative stress is a single component of this. Gerontologists, geriatricians, nutritionists, and dieticians are separated by divergent skills and professional disciplines that need to be bridged to advance preventative as well as treatment strategies. While gerontologists and geriatricians may study the underlying processes of aging, they are less likely to be conversant in the science of nutrition and dietetics. On the other hand, nutritionists and dietitians are less conversant with the detailed clinical background and science of gerontology. This book addresses this gap and brings each of these disciplines to bear on the processes inherent in the oxidative stress of aging. This will aid in better research, treatment and outcome for patients.

    • Sharks in Mexico: Research and Conservation Part B

      • 1st Edition
      • Volume 85
      • May 23, 2020
      • Shawn Larson + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 8 2 2 1 9 9 0
      • eBook
        9 7 8 0 1 2 8 2 2 2 0 0 3
      Sharks in Mexico: Research and Conservation, Volume 85 in the Advances in Marine Biology series, provides in-depth and up-to-date reviews on all aspects of marine biology that will appeal to postgraduates and researchers in marine biology, fisheries science, ecology, zoology and biological oceanography.

    • The Developing Microbiome

      • 1st Edition
      • May 23, 2020
      • Erika Chiong Claud
      • English
      • Paperback
        9 7 8 0 1 2 8 2 0 6 0 2 7
      • eBook
        9 7 8 0 1 2 8 2 0 6 1 7 1
      The Developing Microbiome: Lessons from Early Life focuses on the establishment of the microbiome in early life, exposing it as a key mediator of diseases and health throughout the lifecycle. The content presents a comprehensive view of the status of the field and draws real-world correlations to health and disease states. It collates the significant research being done in the pediatric microbiome research space and bridges the knowledge gap showing the factors that impact health and disease states throughout the lifecycle. Finally, it offers knowledge on how the microbiome is and can be manipulated to promote change. This is a perfect reference for both researchers and clinical scientists who are interested in the role of the infant microbiome in health and disease, as well as gastroenterologists and pediatricians looking to affect change in their patients.

    • Biomaterials Science

      • 4th Edition
      • May 23, 2020
      • William R Wagner + 3 more
      • English
      • Hardback
        9 7 8 0 1 2 8 1 6 1 3 7 1
      • eBook
        9 7 8 0 1 2 8 1 6 1 3 8 8
      The revised edition of the renowned and bestselling title is the most comprehensive single text on all aspects of biomaterials science from principles to applications. Biomaterials Science, fourth edition, provides a balanced, insightful approach to both the learning of the science and technology of biomaterials and acts as the key reference for practitioners who are involved in the applications of materials in medicine.This new edition incorporates key updates to reflect the latest relevant research in the field, particularly in the applications section, which includes the latest in topics such as nanotechnology, robotic implantation, and biomaterials utilized in cancer research detection and therapy. Other additions include regenerative engineering, 3D printing, personalized medicine and organs on a chip. Translation from the lab to commercial products is emphasized with new content dedicated to medical device development, global issues related to translation, and issues of quality assurance and reimbursement. In response to customer feedback, the new edition also features consolidation of redundant material to ensure clarity and focus. Biomaterials Science, 4th edition is an important update to the best-selling text, vital to the biomaterials’ community.

    • Stiehm's Immune Deficiencies

      • 2nd Edition
      • May 23, 2020
      • Kathleen E. Sullivan + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 8 1 6 7 6 8 7
      • eBook
        9 7 8 0 1 2 8 1 7 2 9 5 7
      Stiehm’s Immune Deficiencies: Inborn Errors in Immunity, Second Edition, is ideal for physicians and other caregivers who specialize in immunology, allergies, infectious diseases and pulmonary medicine. It provides a validated source of information for care delivery to patients, covering approaches to diagnosis that use both new genetic information and emphasize screening strategies. Management has changed dramatically over the past five years, so approaches to infection and autoimmunity are emphasized in an effort to improve outcomes and disseminate new information on the uses of targeted therapy.

    • Smart Economic Decision-Making in a Complex World

      • 1st Edition
      • May 22, 2020
      • Morris Altman
      • English
      • Paperback
        9 7 8 0 1 2 8 1 1 4 6 1 2
      • eBook
        9 7 8 0 1 2 8 1 3 1 7 8 7
      Smart Economic Decision-Making in a Complex World is a fresh and reality-based perspective on decision-making with significant implications for analysis, self-understanding and policy. The book examines the conditions under which smart people generate outcomes that improve their place of work, their household and society. Within this work, the curious reader will find interesting open questions on many fascinating areas of current economic debate, including, the role of realistic assumptions robust model building, understanding how and when non-neoclassical behavior is best practice, why the assumption of smart decision-makers is best to understand and explain our economies and societies, and under what conditions individuals can make the best possible choices for themselves and society at large. Additional sections cover when and how efficiency is achieved, why inefficiencies can persist, when and how consumer welfare is maximized, and what benchmarks should be used to determine efficiency and rationality.

    • An Evidence-Based Approach to the Management of Nasopharyngeal Cancer

      • 1st Edition
      • May 22, 2020
      • Baharudin Abdullah + 2 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 4 4 0 3 9
      • eBook
        9 7 8 0 1 2 8 1 4 4 0 4 6
      An Evidence-Based Approach to the Management of Nasopharyngeal Cancer: From Basic Science to Clinical Presentation and Treatment provides a comprehensive overview with updated management procedures for nasopharyngeal carcinoma. Written by experts on the subject, it is organized in a simple yet comprehensive manner to aid in the understanding of this complex condition. The book discusses several topics related to NPC, including epidemiology, pathophysiology, risk factors and treatment (surgical and non-surgical). Additionally, it discusses key features of clinical presentation of NPC, recent advances and promising new therapies. This will be a valuable source for clinicians, graduate students, oncologists and several members of the biomedical field who are interested in understanding nasopharyngeal cancer in a practical and applicable way.

    • OpenVX Programming Guide

      • 1st Edition
      • May 22, 2020
      • Frank Brill + 3 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 6 4 2 5 9
      • eBook
        9 7 8 0 1 2 8 1 6 6 1 9 2
      OpenVX is the computer vision API adopted by many high-performance processor vendors. It is quickly becoming the preferred way to write fast and power-efficient code on embedded systems. OpenVX Programming Guidebook presents definitive information on OpenVX 1.2 and 1.3, the Neural Network, and other extensions as well as the OpenVX Safety Critical standard. This book gives a high-level overview of the OpenVX standard, its design principles, and overall structure. It covers computer vision functions and the graph API, providing examples of usage for the majority of the functions. It is intended both for the first-time user of OpenVX and as a reference for experienced OpenVX developers.

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