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    • Emery and Rimoin’s Principles and Practice of Medical Genetics and Genomics

      • 7th Edition
      • September 30, 2020
      • Reed E. Pyeritz + 2 more
      • English
      • Hardback
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      • eBook
        9 7 8 0 1 2 8 1 2 6 8 3 7
      For decades, Emery and Rimoin’s Principles and Practice of Medical Genetics and Genomics has served as the ultimate resource for clinicians integrating genetics into medical practice. With nearly 5,000 pages of detailed coverage, contributions from over 250 of the world’s most trusted authorities in medical genetics, and a series of 11 volumes available for individual sale, the Seventh Edition of this classic reference includes the latest information on seminal topics such as prenatal diagnosis, genome and exome sequencing, public health genetics, genetic counseling, and management and treatment strategies to complete its coverage of this growing field for medical students, residents, physicians, and researchers involved in the care of patients with genetic conditions. This comprehensive yet practical resource emphasizes theory and research fundamentals related to applications of medical genetics across the full spectrum of inherited disorders and applications to medicine more broadly. In Metabolic Disorders, leading physicians and researchers thoroughly examine medical genetics as applied to a range of metabolic disorders, with emphasis on understanding the genetic mechanisms underlying these disorders, diagnostic approaches, and therapeutics that make use of current genomic technologies and translational studies. Here genetic researchers, students, and health professionals will find new and fully revised chapters on the genetic basis of body mass, amino acid, carbohydrate, iron, copper, lipo protein, and lipid metabolic disorders, as well as organic acidemias, fatty acid oxidation, and peroxisome disorders among others. With regular advances in genomic technologies propelling precision medicine into the clinic, Emery and Rimoin’s Principles and Practice of Medical Genetics and Genomics: Seventh Edition bridges the gap between high-level molecular genetics and practical application and serves as an invaluable clinical tool for health professionals and researchers.

    • Gastroparesis

      • 1st Edition
      • September 30, 2020
      • Richard Mccallum + 3 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 8 5 8 6 5
      • eBook
        9 7 8 0 1 2 8 1 8 5 8 7 2
      Gastroparesis: Pathophysiology, Clinical Presentation, Diagnosis and Treatment is a reference book providing a centralized source of data on gastroparesis collected over the last decade. Contents include the pathophysiology, clinical presentation, diagnostic recommendations and treatment options for gastroparesis. The reference is split into broad subsections, with the strategy of first focusing on the key features of the disease and then turning to controversies, recent developments, patient support resources, the spectrum of treatment – including medical and surgical - and future directions. Chapters will include coverage of important topics like autonomic neuropathy, the brain-gut axis, potential pathophysiological advances at the cellular level, diagnostic and therapeutic options specifically targeted at the pylorus, and the evaluation of the female predominance in gastroparesis. This is a must-have resource for scientists looking to find the next step in their research as well as healthcare professionals ranging from Gastroenterologists to Internists, Surgeons, Nutritionists, Psychiatrists, and Psychologists, Residents and Medical Students who struggle with how to optimally take care of their gastroparetic patients.

    • iPSCs from Diverse Species

      • 1st Edition
      • September 29, 2020
      • Alexander Birbrair
      • English
      • Paperback
        9 7 8 0 1 2 8 2 2 2 2 8 7
      • eBook
        9 7 8 0 3 2 3 8 5 1 8 5 5
      The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. iPSCs from Diverse Species, Volume 2 addresses how induced pluripotent stem cells (iPSCs) can be derived from different species. The volume teaches the reader about modern state-of-the-art methodologies to derive iPSCs from distinct species. This volume will cover how to derive iPSCs from species like nonhuman primates, horses, dogs, pigs, rats, rabbits, and others. It also discusses the importance of iPSCs in species conservation. Detailed description on methods used to obtain iPSCs from humans and other species expands the knowledge and understanding of stem cell biology and provides a potent tool to model diseases. The volume is written for researchers and scientists in stem cell biology, and regenerative medicine and is contributed by world-renowned authors in the field.

    • Advances in Carbohydrate Chemistry and Biochemistry

      • 1st Edition
      • Volume 77
      • September 29, 2020
      • David C. Baker
      • English
      • Hardback
        9 7 8 0 1 2 8 2 0 9 9 3 6
      • eBook
        9 7 8 0 1 2 8 2 0 9 9 4 3
      Advances in Carbohydrate Chemistry and Biochemistry, Volume 77, the latest release in this ongoing series, highlights new advances in the field, with this new volume presenting interesting chapters on Temporary Ether Protecting Groups at the Anomeric Center in Complex Carbohydrate Synthesis and Mucopolysaccharidosi... Type II (Hunter Syndrome): Clinical and Biochemical Aspects of the Disease and Approaches to its Diagnosis and Treatment.

    • International Review Research in Developmental Disabilities

      • 1st Edition
      • Volume 58
      • September 28, 2020
      • English
      • Hardback
        9 7 8 0 1 2 8 2 0 6 9 6 6
      • eBook
        9 7 8 0 1 2 8 2 0 6 9 7 3
      International Review of Research in Developmental Disabilities, Volume 58, highlights new advances in the field, with this new volume presenting interesting chapters on topics including The Importance of Informal Supports in Meeting the Daily Needs of Adults with IDD, Forms and Functions of Special Education Advocacy: Supporting Families of Children with IDD, The Disability Training Needs of Healthcare Professionals, Health promotion and obesity risk in Intellectual and Developmental Disabilities, Community-based participatory approaches to IDD research, and Measuring behavioral problems in children with Down syndrome.

    • Elephants Under Human Care

      • 1st Edition
      • September 27, 2020
      • Paul A. Rees
      • English
      • Paperback
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      • eBook
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      This book draws together, for the first time, the published research on the behaviour, ecology and welfare of elephants living in zoos, circuses, logging camps and other captive environments in a single comprehensive volume. It takes a multi-disciplinary approach, considering the work of zoo biologists, animal behaviour and welfare scientists, veterinarians, philosophers, zoo educators, tourism specialists, conservation biologists, lawyers and others with a professional interest in elephants. Elephants under Human Care: The Behaviour, Ecology, and Welfare of Elephants in Captivity is a valuable resource for zoo biology and animal welfare researchers. It is also useful for students and zoo professionals and managers looking for a comprehensive guide to current research on captive elephants. Although not intended as a husbandry manual, the book discusses some of the elephant welfare standards developed by the Association of Zoos and Aquariums (AZA) and the British and Irish Association of Zoos and Aquariums (BIAZA) and their relationship to current knowledge of captive elephants.

    • Advances in Immunology

      • 1st Edition
      • Volume 147
      • September 25, 2020
      • English
      • Hardback
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      • eBook
        9 7 8 0 1 2 8 2 0 7 4 1 3
      Advances in Immunology, Volume 147, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology. Chapters in this new release include Histone deacetylases as targets in autoimmune and autoinflammatory diseases, The advancing area of the mechanisms involved in the evolution of HIV-1 neutralizing antibodies, T cells in latent viral infections, Communications of dendritic cells with T cells and NK cells in cancerous tissues, Mechanism and Regulation of Class Switch Recombination by IgH transcriptional Control Elements, IL-2 partial agonist, Preserving Immune Homeostasis with A20, The design of vaccine strategies to elicit HIV-1 broadly neutralizing antibodies.

    • Sustainable Fuel Technologies Handbook

      • 1st Edition
      • September 25, 2020
      • Suman Dutta + 1 more
      • English
      • Paperback
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      • eBook
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      Sustainable Fuel Technologies Handbook provides a thorough thermodynamic analysis of new and current methods to give detailed insight into energy efficiency processes. This book includes the production methods, storage systems, and applications in various engines, as well as the safety related issues associated with all stages of production, storage, and utilization. With a comparison of cost implications and a techno-economic evaluation checking the feasibility of sustainable fuel use, this handbook is an invaluable reference source for researchers, professionals, and scientists working in the field of sustainability. The present power from solar, biomass, wind, hydrogen and other forms of renewable energy generated from sustainable sources can be harvested by various means and utilized in a variety of industries, supporting the need for clean fuels in modern society. However, there is still limited global availability and insufficient storage, which are required for efficient and effective harvesting of sustainable fuels.

    • Behavioral Economics for Tourism

      • 1st Edition
      • September 24, 2020
      • Milena S. Nikolova
      • English
      • Paperback
        9 7 8 0 1 2 8 1 3 8 0 8 3
      • eBook
        9 7 8 0 1 2 8 1 3 8 1 2 0
      Behavioral Economics for Tourism applies behavioral perspectives to business and policy challenges in the tourism industry. The book enables professionals and early career researchers to succeed by focusing on market and consumer trends, technological advancements, and the modern tourist. It covers the transformation of purchasing decisions, tourism hosting dynamics, digital mediation and disintermediation of tourism organizations, service design, and planning policy considerations. The volume concludes with case studies illustrating successful and unsuccessful behavioral tactics and strategies for tourism businesses and organizations.

    • Neurobiology of Alcohol and the Brain

      • 1st Edition
      • September 24, 2020
      • Ashok K. Singh
      • English
      • Paperback
        9 7 8 0 1 2 8 1 9 6 8 0 9
      • eBook
        9 7 8 0 1 2 8 1 9 8 9 1 9
      According to the 2018 National Survey on Drug Use and Health, 14.4 million adults aged 18 and older had alcohol use disorder (AUD). Mixing alcohol with other drugs such as opioids or cocaine has become an emerging trend, exacerbating public health concerns and may synergistically augment the seriousness of the adverse effects such as withdrawal symptoms, cardiovascular disorders, liver damage, reproductive abnormalities, and behavioral abnormalities. Despite the seriousness of the situation, possible mechanisms underlying the addiction and the withdrawal symptoms is not yet understood. This has been one of the key hindrances in developing effective treatment. Neurobiology of Alcohol and the Brain addresses the addiction-related problems reviewing both the mechanisms and withdrawal system with alcohol addiction. First, the book discusses the mechanisms of the rewarding and aversive effects, including addiction and the withdrawal symptoms of alcohol drinking. Next, alcohol's interaction with other drugs and ensuing adverse consequences is discussed including current and novel treatments against alcoholism. This is followed by a closer look at mental health and alcohol use disorder comorbidity. Lastly, the reader is provided with examples of an experimental study that describes possible protective effects of gold nanoparticles against alcohol addiction in rats subjected to alcohol self-administration. Neurobiology of Alcohol and the Brain will unlock the mechanistic diversities of alcoholism helping to facilitate future developments of new, personalized treatment options for patients suffering from alcohol addiction.

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