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Academic Press

Chromatin Readers in Health and Disease
1st Edition
Volume 35
Olivier Binda
English
Chromatin Readers in Health and Disease, Volume 35, a new release in the Translational Epigenetics series, gathers and makes actionable our current understanding of how chromatin readers regulate access to genetic information, and how their aberrant regulation can contribute to human pathologies. Chromatin readers discussed include 14-3-3 Dinshaw, ADD, Ankyrin, BAH, BET, BIR, BRCT, bromodomains and Kac readers, chromodomains and chromobarrel readers, citrullination readers, macrodomains and poly-ADP-ribose readers, MBT, PHD and double PHD, PWWP, SUMO (H4K12) readers, Tudor and TTD, UDR and ubiquitin, WD40, YEATS (crotonyl reader), MBD, SRA, and Methyl-RNA readers.In the book, more than a dozen leaders in the field examine a range of protein readers, their relationship to human disease, and the early therapeutics that act as chromatin signaling factors to treat cancers and Huntington's disease, among other disorders.
Chromatin Remodeling Complexes and Transcriptional Coregulators
1st Edition
Volume 53
English
Chromatin Remodeling Complexes and Transcriptional Coregulators, Volume 53, the latest release in The Enzymes series highlights new advances in the field, with interesting new chapters that cover Perspectives on Chromatin Remodeling, The functions of ISWI-type remodelers in yeast, Conserved mechanisms of NuRD function in hematopoietic gene expression, The SIN3 complex as a metabolic epigenetic regulator, Soft repression and chromatin modification by conserved transcriptional corepressors, The NPAC-LSD2 complex in nucleosome demethylation, Role of intrinsically disordered domains in transcriptional regulation, and Regulation of the Recovery of Cancer from Therapy Exposure by Noncoding RNAs.
Hybrid Poly-generation Energy Systems
Thermal Design and Exergy Analysis
1st Edition
Mehdi Mehrpooya + 3 more
English
Hybrid Poly-generation Energy Systems: Thermal Design and Exergy Analysis provides an analysis of the latest technologies and concepts of hybrid energy systems, focusing on thermal applications. The book guides readers through an introduction to hybrid poly-generation systems and the storage options available before working through the types of hybrid systems, including solar, fuel cells, combustion, and heating and cooling. An analysis of the economic and environmental impact of each system is included, as well as methods and approaches for exergy and energy improvement analysis. This book can be used as a tool for understanding new concepts in this emerging field and as a reference for researchers and professionals working on the integrated cogeneration of power systems.
A Progressive Approach to Applied Behavior Analysis
The Autism Partnership Method
1st Edition
Justin B Leaf + 7 more
English
Approximately 1 in 36 children in the United States will be diagnosed with autism spectrum disorder (ASD) and that number is expected to rise according to the CDC. Interventions based on the science of applied behavior analysis (ABA) are one of the most common interventions for autistic individuals. One of the biggest problems facing the field of ABA-based interventions is ineffectiveness of intervention approaches due to the rigid application of ABA-based interventions. Progressive Approach to Applied Behavior Analysis provides practicing behavior analysts (e.g., BCBAs, BCaBAs, RBTs) and other clinicians with an in-depth introduction to a Progressive Approach to ABA and how it applies to common teaching methods within ABA-based interventions. This includes research and guidelines for implementing a Progressive Approach to ABA, potentially increasing the likelihood of meaningful outcomes for individuals diagnosed with ASD. This will become the guide for practitioners on how to use clinical judgment and in-the-moment assessment across various procedures.
Medical Image Analysis
1st Edition
Alejandro Frangi + 2 more
English
Medical imaging is increasingly at the base of many breakthroughs in biomedical sciences, becoming a fundamental enabling technology of biomedical scientific progress. Medical Image Analysis presents practical knowledge on medical image computing and analysis and is written by top educators and experts in the field. This text is a modern, practical, broad, and self-contained reference that conveys a mix of essential methodological concepts within different medical domains, reflecting the nature of the discipline today, making it suitable as a course text and a self-learning resource.
Advances in Quantum Chemistry
1st Edition
Volume 88
English
Advances in Quantum Chemistry, Volume 88 presents the latest ongoing research at the forefront of Electronic structure theory. Chapters in the updated release include Spin-constrained Hartree-Fock and the generator coordinate method for the 2-site Hubbard model, Analytical evaluation of Hylleraas-CI Coulomb and Hybrid two-center Integrals over Slater orbitals, Hartree-Fock-Roothaa... Theory of Molecular Compton Profiles Via Position Space Method, Analysis of Research Trend on the Molecular Integrals Over Slater Type Orbitals, An efficient approximation for accelerating convergence of numerical power series, Results for the 1D−Schroedinger equation, The aims and objectives of algebraic molecular orbital theory, and much more.
Circulating Tumor Cells, From Biotech Innovation to Clinical Utility Part A
1st Edition
Volume 381
English
"Circulating Tumor Cells, from biotech innovation to clinical utility" provides an overview of the most recent technological and clinical advances with regards to the study of circulating tumor cells (CTCs) in solid tumors. The volumes cover studies on CTCs in breast, prostate, colorectal and lung cancer, with a focus on clinical utility, and also include methodological and biological topics such as CTC culture, multi-omic characterization of CTCs, atypical CTC populations and interaction between CTCs and immunity.
Adenosine A2A Receptor Antagonists
1st Edition
Volume 170
English
Adenosine A2A Receptor Antagonists, Volume 170 in the International Review of Neurobiology series highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including A2A Adenosine Receptor Agonists, Antagonists, Inverse Agonists and Partial Agonist, Chemistry – agonists, antagonists, partial agonists, inverse agonists, Functional roles of adenosine receptors – biochemistry and neuronal plasticity, A2A and Depression, A2AR and glial function, The adenosine A2A receptor in the basal ganglia: expression in health and disease, heteromerization, functional selectivity and signaling, How and why A2a receptor become to be a therapeutic target in Parkinson’s disease therapy, and much more.
Crystallography of Protein Dynamics
1st Edition
Volume 688
English
Crystallography of Protein Dynamics, Volume 688, the latest release in this important series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.
Inoculating Cities
Case Studies of the Urban Response to the COVID-19 Pandemic
1st Edition
Rebecca Katz + 1 more
English
Inoculating Cities: Case Studies of the Urban Response of the COVID-19 Pandemic uses detailed case studies to document and describe how cities located in high, middle and low-income countries responded to the COVID-19 pandemic. City governments and municipal authorities exist and operate in extremely varied contexts (i.e., socioeconomic, demographic, legal and governance, etc.) and intentionally documenting the experiences in these different contexts provides guidance to decision-makers for future preparedness and response activities. This volume highlights the innovative solutions throughout the pandemic as described by the people who designed and implemented pandemic response efforts in their cities. In addition, it identifies successful models that can be adopted in the future by city leaders around the world.

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