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    • Targeting Signaling Pathways in Solid Tumors Part A

      • 1st Edition
      • Volume 385
      • April 23, 2024
      • English
      • Hardback
        9 7 8 0 4 4 3 2 3 5 4 6 7
      • eBook
        9 7 8 0 4 4 3 2 3 5 4 7 4
      Targeting Signaling Pathways in Solid Tumors, Part A, Volume 385 in the International Review of Cell and Molecular Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Drugging the Undruggable: Advances in Targeting KRAS Signaling in Solid Tumors, Emerging Trends in Gastrointestinal Cancers: Targeting Developmental Pathways in their Carcinogenesis and Tumor Progression, Importance of targeting various cell signaling pathways in solid cancers, Targeting signaling pathways in cancer stem cells: a potential approach for developing novel anticancer therapeutics, Factors affecting heterogeneity in breast cancer microenvironment: A narrative review, and much more.Additional sections cover Exploring TLR Signaling Pathways as Promising Targets in Cervical Cancer: The Road Less Travelled

    • Introduction to Protein Mass Spectrometry

      • 2nd Edition
      • April 22, 2024
      • Pradip K. Ghosh
      • English
      • Paperback
        9 7 8 0 4 4 3 1 4 0 1 5 0
      • eBook
        9 7 8 0 4 4 3 1 3 9 2 0 8
      Introduction to Protein Mass Spectrometry, Second Edition provides a comprehensive overview of this increasingly important, yet complex, analytical technique. This book enables readers to understand how determinations about protein identity from mass spectrometric data are made. Coverage begins with the technical basics, including preparations, instruments, and spectrometric analysis of peptides and proteins, before exploring applied use in biological applications, bioinformatics, database, and software resources. This new edition is fully updated to include the latest developments in the field and will feature new content covering recent progress in the areas where there have been the most exciting advances. These include PNNL’s multilevel-PCB-based SLIM realization, SLIM-Agilent QQQ field trials; employment of SLIM-IMS-cryo-IR combination in molecular structure determination; proximity-labelling mass spectrometry, and applications in neuroscience.

    • An Introduction to the Microbiome in Health and Diseases

      • 1st Edition
      • April 22, 2024
      • Charles Oluwaseun Adetunji + 3 more
      • English
      • Paperback
        9 7 8 0 3 2 3 9 1 1 9 0 0
      • eBook
        9 7 8 0 3 2 3 9 1 4 7 2 7
      The gut microbiome plays a very important role in your health. It controls digestion and has a beneficial impact on your immune system and other aspects of health. An Introduction to the Microbiome in Health and Diseases is a prelude to subsequent books on this topic which provides in-depth coverage on the microbiome from basic to clinical microbiology. This introductory volume offers an overview on the microbiome and explores the role of the human microbiome in health and disease outcomes. It examines the compositional structure and molecular approaches to microbiome characterization and identification. Additional coverage also includes an introduction to animal microbiomes, plant microbiomes, epigenetic programming, gut microbiota and the impact of diet and exercise, as well as the relationship between the microbiome and COVID-19.

    • The Covid-19 Response in New York City

      • 1st Edition
      • April 21, 2024
      • Syra S. Madad + 2 more
      • English
      • Paperback
        9 7 8 0 4 4 3 1 8 7 5 5 1
      • eBook
        9 7 8 0 4 4 3 1 8 7 5 6 8
      The COVID-19 Response in New York City: Crisis Management in the Largest Public Health System provides an historical accounting of the response to the COVID-19 pandemic through the eyes of the largest public health system in the United States. The book offers a roadmap to guide healthcare systems and their providers in the event of future pandemics. Readers will learn about surge staffing and level loading, as well as tips from the ED and ICUs on how to respond to an unprecedented influx of inpatients. Written by healthcare providers who were at the epicenter of the pandemic in New York City, this book provides a sound accounting of the response to the pandemic in one of the world's largest cities.

    • Neurological and Neurosurgical Emergencies

      • 1st Edition
      • April 20, 2024
      • Indu Kapoor + 2 more
      • English
      • Paperback
        9 7 8 0 4 4 3 1 9 1 3 2 9
      • eBook
        9 7 8 0 4 4 3 1 5 6 6 2 5
      Neurological and Neurosurgical Emergencies addresses emergencies in all fields of neuroscience, including disciplines like Neurology, Neurosurgery, Neuroanaesthesia, and Neuroradiology. This volume covers neurosurgical emergencies, like hydrocephalus, brain edema, intracranial bleed, intracranial hematoma, infection, and trauma, alongside neurovascular emergencies like acute ischemic stroke, non-traumatic, aneurysmal subarachnoid hemorrhage, carotid cavernous fistula, and arteriovenous malformation.In addition, the book discusses common emergencies in neurology, including status epilepticus, refractory epilepsy, super-refractory epilepsy, and neuromuscular disorders. Beginning with neurological examination of patients through to anesthetic management of various emergencies, this book features clear images that accompany each emergency with learner-friendly features such as flow-charts, figures, text boxes, and algorithms. This book provides insights into all possible aspects of emergency management and the anesthetic management of such patients.

    • Regenerative Medicine in the Genitourinary System

      • 1st Edition
      • April 19, 2024
      • Farshid Sefat + 1 more
      • English
      • Paperback
        9 7 8 0 4 4 3 1 5 8 3 4 6
      • eBook
        9 7 8 0 4 4 3 1 5 8 3 5 3
      Regenerative Medicine in the Genitourinary System gives the reader a comprehensive overview of tissue engineering used to treat genitourinary disorders and infertility, also providing a great learning platform for researchers in different fields such as cell biology, pharmaceutics, clinicians, chemists, material scientists, and more. The book covers the latest innovations on the subject, but also acts as a resource for tissue engineering applications and regenerative medicine. Over the last several decades, tissue engineering has continued to make considerable advancements in therapeutic and clinical strategies that address male/female urological or genitourinary diseases.Although several articles have been published on this topic, there are very few book chapters and no single book currently available dedicated to this topic.

    • Fluorine Metabolism, Transport and Enzymatic Chemistry

      • 1st Edition
      • Volume 696
      • April 19, 2024
      • English
      • Hardback
        9 7 8 0 4 4 3 2 3 6 4 3 3
      • eBook
        9 7 8 0 4 4 3 2 3 6 4 4 0
      Fluorine Metabolism, Transport and Enzymatic Chemistry, Volume 696 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting topics on Fluorine Metabolism, Transport, and Enzymatic Chemistry. Chapters in this new release include Determination of fluoride sensitivity and resistance in oral biofilm models, NMR methods to detect fluoride binding and transport by membrane proteins, Biotransformation of fluorinated drugs and xenobiotics by the model fungus Cunninghamella elegans, Measurement of fluoride efflux from lipid vesicles and cells, Defluorination of PFAS by Acidimicrobium sp. A6 and Potential Applications for Remediation, and more.Additional chapters cover Computational approaches to investigate F- binding, selectivity and transport in F- exporters, Defluorination as a key trait to gauge the biodegradability of fluorinated pollutants: challenges and opportunities, Patch-Clamp Electrophysiology of Fluoride Channels in Saccharomyces cerevisiae, and Synthesis of fluorophenylalanine-... proteins in HEK cells.

    • Overview of Inflammatory Breast Cancer: Updates

      • 1st Edition
      • Volume 384
      • April 18, 2024
      • English
      • Hardback
        9 7 8 0 4 4 3 1 3 3 4 8 0
      • eBook
        9 7 8 0 4 4 3 1 3 3 4 9 7
      International Review of Cell and Molecular Biology, Volume 381 highlights new advances in the field, with this new volume presenting interesting topic on Overview of Inflammatory Breast Cancer: Updates.

    • Advances in Applied Microbiology

      • 1st Edition
      • Volume 126
      • April 18, 2024
      • English
      • Hardback
        9 7 8 0 4 4 3 2 9 5 6 0 7
      • eBook
        9 7 8 0 4 4 3 2 9 5 6 1 4
      Advances in Applied Microbiology, Volume 126 continues the comprehensive reach of this widely read and authoritative review source in microbiology where users will find invaluable references and information on a variety of areas relating to the topics of microbiology.

    • An Introductory Handbook of Bayesian Thinking

      • 1st Edition
      • April 17, 2024
      • Stephen C. Loftus
      • English
      • Paperback
        9 7 8 0 3 2 3 9 5 4 5 9 4
      • eBook
        9 7 8 0 4 4 3 2 9 1 1 1 1
      An Introductory Handbook of Bayesian Thinking brings Bayesian thinking and methods to a wide audience beyond the mathematical sciences. Appropriate for students with some background in calculus and introductory statistics, particularly for nonstatisticians with a sufficient mathematical background, the text provides a gentle introduction to Bayesian ideas with a wide array of supporting examples from a variety of fields.

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