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Academic Press

  • Plant-Based Drug Discovery

    Unveiling Molecular Targets for Metabolic Conditions
    • 1st Edition
    • Mamta Bisht + 2 more
    • English
    Plant-Based Drug Discovery: Unveiling Molecular Targets for Metabolic Conditions provides an in-depth examination of the molecular mechanisms of phytochemicals and their potential in treating metabolic diseases. This comprehensive guide begins with an introduction to the prevalence and impact of metabolic disorders, emphasizing the significant role of phytochemicals in their management. The book delves into scientific concepts and research findings, offering valuable insights for researchers and healthcare professionals in the fields of molecular biology, biochemistry, pharmacology, and biotechnology. Chapters cover various crucial topics such as oxidative stress, epigenetic mechanisms, and mitophagy.In addition, they explore the targeting of molecular chaperones and the molecular targets of plant nutraceuticals for treating obesity, cardiovascular disease, and type 2 diabetes. The book also addresses technological advances, including AI and nanotechnology, highlighting opportunities and challenges in improving the use of plant molecules for metabolic disorder treatments. It serves as an essential resource for those engaged in drug discovery and related areas.

  • Animal Models of Disease Part D

    • 1st Edition
    • Volume 197
    • English
    Animal Models of Disease, Part D, Volume 197 in the Methods in Cell Biology series presents significant advancements in understanding disease mechanisms through animal models. This volume features chapters on timely topics such as characterizing tumor-infiltrating group 1 innate lymphoid cells in PyMT breast tumors and using zebrafish to unravel the molecular mechanisms of Alzheimer’s disease. The book also covers colitis mouse models and appropriate models for studying diabetes pathophysiology, demonstrating its comprehensive approach to current research.Additional sections cover evaluating polyglutamine protein aggregation in transgenic Caenorhabditis elegans models of Huntington's disease and studying tumor responses to radioimmunotherapy in ovarian cancer models. It also highlights the antimicrobial regime for gut microbiota depletion in mice and the biodistribution of metallic nanoparticles for lymphoma studies. This book is an essential resource for researchers seeking to explore disease mechanisms and therapeutic approaches through animal models.

  • Handbook of Intervention Science

    From Design to Implementation
    • 1st Edition
    • Laura N.Gitlin + 1 more
    • English
    Handbook of Intervention Science: From Design to Implementation discusses multiple approaches for developing and advancing interventions at the individual, family, community, health system, and policy level. The book focuses on creating interventions suitable for diverse populations from racial, ethnical, geographical, and socioeconomical perspectives. Combining best practices with a practical approach, the book enables readers to advance their intervention research. It covers intervention design, data capture in trials, and evaluation. Decision trees help illustrate when to move forward with an implementation relative to the need for further work.

  • Less-Supervised Segmentation with CNNs

    Scenarios, Models and Optimization
    • 1st Edition
    • Jose Dolz + 2 more
    • English
    Less-Supervised Segmentation with CNNs: Scenarios, Models and Optimization reviews recent progress in deep learning for image segmentation under scenarios with limited supervision, with a focus on medical imaging. The book presents main approaches and state-of-the-art models and includes a broad array of applications in medical image segmentation, including healthcare, oncology, cardiology and neuroimaging. A key objective is to make this mathematical subject accessible to a broad engineering and computing audience by using a large number of intuitive graphical illustrations. The emphasis is on giving conceptual understanding of the methods to foster easier learning.This book is highly suitable for researchers and graduate students in computer vision, machine learning and medical imaging.

  • Advances in Child Development and Behavior

    • 1st Edition
    • Volume 69
    • English
    Advances in Child Development and Behavior, Volume 69, the latest release in this classic resource on the field of developmental psychology, includes a variety of timely updates, with this new volume presenting interesting chapters written by an international board of authors. Chapters in this new release include Autonomic and Attentional Pathways in the Emergence of Autism: Bridging Mechanisms and Real-World Contexts in Infancy, The Sound-of-Words model: a developmental perspective of phonolexical acquisition, The Development of Children's Beliefs about Ability, and Assessing Children’s Spatial Thinking: Insights, Challenges, and Implications,

  • Biosensing the Future

    Wearable, Ingestible and Implantable Technologies for Health and Wellness Monitoring Part B
    • 1st Edition
    • Volume 216
    • English
    Biosensing the Future: Wearable, Ingestible and Implantable Technologies for Health and Wellness Monitoring, Part B, Volume 216 covers the rapidly evolving field of biosensors, highlighting their transformative role in modern healthcare, disease monitoring, and personalized medicine. Chapters in this new release include Technologies and emerging trends in wearable biosensing, Implantable biosensors: advancements and applications, Neural implants: restoring function and enhancing quality of life, Ingestible biosensors: monitoring health from within, Ingestible biosensors for monitoring digestive health and nutritional monitoring, Ingestible biosensors for drug delivery monitoring, Artificial intelligence in wearable biosensing: enhancing data analysis and decision-making, and much more.Additional sections cover Wearable Privacy, Ethical and regulatory landscape of wearable, ingestible, and implantable technologies, Characterization of skeletal muscle contraction using a flexible and wearable ultrasonic sensor, Wearable Biosensors for Climate Change and Health Research, and much more. The book systematically explores the integration of biosensing technologies into wearable, ingestible, and implantable devices, offering a multidimensional perspective on their applications, advancements, and future directions.

  • Methodology in Radiomics

    Step-by-step Guide in Radiomics Pipeline
    • 1st Edition
    • Salvatore Claudio Fanni + 3 more
    • English
    Methodology in Radiomics: Step-by-step Guide in Radiomics Pipeline is an essential resource for anyone interested in the rapidly evolving field of radiomics. This comprehensive guide delves into the history and fundamental principles of radiomics, providing readers with a clear understanding of how to implement each step in the radiomic pipeline. The book is designed to bridge the gap between radiomics research and clinical practice, making it an invaluable reference for imaging scientists, researchers, and medical professionals. The book not only covers the basics but also includes troubleshooting techniques to overcome common challenges.It discusses current research and future directions, offering insights into the potential of radiomics in clinical settings. This guide ensures that readers are well-equipped to navigate the complexities of radiomics, fostering a deeper understanding of its applications and advances in medical imaging.

  • Practical Stress Management

    A Comprehensive Workbook
    • 9th Edition
    • John A. Romas + 1 more
    • English
    Practical Stress Management: A Comprehensive Workbook, Ninth Edition provides an accessible and actionable guide for individuals seeking to improve their ability to cope with stress effectively. Featuring engaging activities, insightful explanations, and evidence-based strategies, this workbook equips readers with the tools to identify stressors, understand their impact, and implement techniques to maintain mental and physical well-being. Its practical orientation ensures that users not only learn about stress management but also apply these principles directly to their lives, fostering resilience and balance.Packed with user-friendly exercises, case studies, and new features tailored for contemporary needs, the book supports both personal growth and professional development. Whether for individuals navigating daily pressures or professionals assisting others in stress management, this comprehensive workbook provides a valuable resource for building healthier habits and improving overall quality of life.

  • Advances in Heterocyclic Chemistry

    • 1st Edition
    • Volume 147
    • English
    Advances in Heterocyclic Chemistry, Volume 147 in this ongoing series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. New chapters in this release include Synthesis and chemistry of pyridazin-3(2H)-ones... Denitrogenative Transformations of Polynitrogen Heterocycles, Pyridinium-phenolate Dyes: Preparation and Properties, Recent Advances in the Mechanochemical Synthesis and Derivatization of Heterocycles, Recent Advances in the Synthesis of 7- and 8- Membered Heterocycles via Domino and Multicomponent Reactions (from 20?-2024), and Total Synthesis of Natural Products with Isoflavone Skeletons and Other Heterocycles.

  • Pharmacological Targets in Metabolic Diseases

    Challenges and Opportunities
    • 1st Edition
    • Marcos Roberto de Oliveira
    • English
    Pharmacological Targets in Metabolic Diseases: Challenges and Opportunities is a complete reference on possible drug development targets to be leveraged in therapeutic developments. Covering both signaling pathways and specific proteins, the book presents ways to modulate the molecular and cellular alterations observed in metabolic diseases and disorders through the application of new or classical drugs. The comprehensive coverage starts by providing an overview of metabolic diseases and disorders, biological alterations, and pharmacological targets. This section covers targets at both molecular, and subcellular and cellular levels. The next section in the book is focused on pharmaceutical targeting of organs, including a dedicated chapter to the gut-brain axis. Next comes a thorough review of the current advances in metabolic syndrome research. Section VI is focused on inborn errors of metabolism and is followed by a section devoted to natural molecules and their pharmacological potential to treat these conditions. The Editor introduces next a whole section dedicated to the role of the microbiota in metabolic diseases therapeutics. The following sections cover the impact of aging, nanotechnology, the environment, and finally diagnostic techniques in metabolic diseases and disorders. Pharmacological Targets in Metabolic Diseases: Challenges and Opportunities meet the needs of pharmacology researchers looking for a comprehensive and authoritative source of information on possible therapeutic targets to treat these conditions. Research physicians, nutritionists, pharmacists, and biologists can benefit from the detailed information provided at the different levels of targets identified to treat metabolic diseases and conditions.

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